Optimization and Identification of Antioxidant Peptide from Underutilized Dunaliella salina Protein: Extraction, In Vitro Gastrointestinal Digestion, and Fractionation
Open accessAbstract
DPPH• scavenging peptides (<3kDa) from underutilized Dunaliella salina protein were obtained by the following successive treatment, i.e., ultrasound extraction, simulated in vitro gastrointestinal digestion hydrolyzation, and membrane ultrafiltration classification. The optimal condition for ultrasound-assisted extraction was an ultrasound wave with 800 W of power treating a mixture of 60 mL of 1.0 mol L−1 NaOH and 2 g algae powder for 15 min. A high correlation (r=0.8146) between DPPH• scavenging activity and yield of the intact peptides showed their antioxidant capacity. Simulated in vitro digestion assay resulted in excellent DPPH• scavenging activity of the total peptide, amounting to (86.5 ± 10.1)%, comparing with the nondigestion samples at (46.8 ± 6.5)%. After fractionation, the 500-1000 Da fraction exhibited the highest DPPH• scavenging activity (81.2 ± 4.0)%, increasing 1.5 times due to digestion. Then, the 500-1000 Da fraction was analyzed by RPLC-Q Exactive HF mass spectrometer, and 4 novel peptides, i.e., Ile-Leu-Thr-Lys-Ala-Ala-Ile-Glu-Gly-Lys, Ile-Ile-Tyr-Phe-Gln-Gly-Lys, Asn-Asp-Pro-Ser-Thr-Val-Lys, and Thr-Val-Arg-Pro-Pro-Gln-Arg, were identified. From these amino acid sequences, hydrophobic residues accounted for 56%, which indicated their high antioxidant property. The results indicated that underutilized protein of Dunaliella salina could be a potential source of antioxidative peptides through simulated in vitro gastrointestinal digestion.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Peptides from Dunaliella salina (ILTKAAIEGK, IIYFQGK) and Nannochloropsis oculata (GMNNLTP, LEQ) have demonstrated antioxidant and ACE inhibitory effects relevant to blood pressure regulation.
“Similarly, peptides from Dunaliella salina (Chlorophyta) (e.g. ILTKAAIEGK, IIYFQGK) and Nannochloropsis oculata (GMNNLTP, LEQ) have demonstrated antioxidant and ACE inhibitory effects relevant to blood pressure regulation, respectively [63,67].”
From Navigating the potential of algal peptides: health effects, market applications, and scientific challenges (2026) · cites this paper as [67]
The Abstract and Results §3.5 identify ILTKAAIEGK and IIYFQGK in a Dunaliella salina fraction that demonstrated DPPH radical-scavenging activity. The paper infers antioxidant properties for the identified peptides from their sequences, but does not report testing either peptide individually. In the citing sentence, the Nannochloropsis peptides and ACE inhibition are attributed to the other citation, not this source. (LLM, conf=0.85)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Effect of ultrasound on the technological properties and bioactivity of food: a review
Soria, A. C., & Villamiel, M. (2010) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2010.04.003 · Cited by 1,008 · see citing works
The Structure-Activity Relationship of the Antioxidant Peptides from Natural Proteins
Zou, T., He, T., Li, H., Tang, H., & Xia, E.-Q. (2016) · Molecules · doi:10.3390/molecules21010072 · Cited by 884 · see citing works
Self-citationPhysical properties of ultrasound treated soy proteins
Jambrak, A. ., Lelas, V., Mason, T. J., Krešić, G., & Badanjak, M. (2009) · Journal of Food Engineering · doi:10.1016/j.jfoodeng.2009.02.001 · Cited by 523 · see citing works
Barbarino, E., & Lourenço, S. O. (2005) · Journal of Applied Phycology · doi:10.1007/s10811-005-1641-4 · Cited by 416 · see citing works
Sheih, I., Wu, T., & Fang, T. J. (2009) · Bioresource Technology · doi:10.1016/j.biortech.2009.02.014 · Cited by 397 · see citing works
Malik, M. A., SHARMA, H. K., & Saini, C. S. (2017) · Ultrasonics Sonochemistry · doi:10.1016/j.ultsonch.2017.05.026 · Cited by 370 · see citing works
Algae based biorefinery—How to make sense?
Trivedi, J., Aila, M., Bangwal, D. P., Kaul, S., & Garg, M. O. (2015) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2015.03.052 · Cited by 347 · see citing works
Tang, C., Wang, X., Yang, X., & Li, L. (2008) · Journal of Food Engineering · doi:10.1016/j.jfoodeng.2008.12.017 · Cited by 261 · see citing works
The scientific evidence for the role of milk protein-derived bioactive peptides in humans: A Review
Nongonierma, A. B., & Fitzgerald, R. J. (2015) · Journal of Functional Foods · doi:10.1016/j.jff.2015.06.021 · Cited by 235 · see citing works
Potential anti-inflammatory natural products from marine algae
Fernando, I. P. S., Nah, J., & Jeon, Y. (2016) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2016.09.023 · Cited by 225 · see citing works
Potential biomedical applications of marine algae
Wang, H.-M. D., Li, X.-C., Lee, D.-J., & Chang, J.-S. (2017) · Bioresource Technology · doi:10.1016/j.biortech.2017.05.198 · Cited by 217 · see citing works
Antioxidant efficacy of sesame cake extract in vegetable oil protection
Suja, K. P., Abraham, J. T., Thamizh, S. N., Jayalekshmy, A., & Arumughan, C. (2003) · Food Chemistry · doi:10.1016/s0308-8146(03)00248-6 · Cited by 201 · see citing works
Extraction and characterization of protein from Irish brown seaweed Ascophyllum nodosum
Kadam, S. U., Álvarez, C., Tiwari, B. K., & O’Donnell, C. P. (2016) · Food Research International · doi:10.1016/j.foodres.2016.07.018 · Cited by 194 · see citing works
Ko, S., Kim, D., & Jeon, Y. (2012) · Food and Chemical Toxicology · doi:10.1016/j.fct.2012.04.022 · Cited by 192 · see citing works
He, W., Su, G., Sun‐Waterhouse, D., Waterhouse, G. I. N., Zhao, M., & Yang, L. (2018) · Food Chemistry · doi:10.1016/j.foodchem.2018.08.057 · Cited by 131 · see citing works
Delgado, M. C. O., Nardo, A. E., Pavlović, M. D., Rogniaux, H., Añón, M. C., & Tironi, V. A. (2015) · Food Chemistry · doi:10.1016/j.foodchem.2015.11.092 · Cited by 126 · see citing works
Ultrasound-assisted extraction of oleanolic acid and ursolic acid from Ligustrum lucidum Ait
Xia, E.-Q., Yu, Y.-Y., Xu, X., Deng, G., Guo, Y., & Li, H. (2011) · Ultrasonics Sonochemistry · doi:10.1016/j.ultsonch.2011.11.014 · Cited by 117 · see citing works
Self-citationUltrasound-assisted extraction of phillyrin from Forsythia suspensa
Xia, E.-Q., Ai, X.-X., Zang, S.-Y., Guan, T.-T., Xu, X., & Li, H. (2010) · Ultrasonics Sonochemistry · doi:10.1016/j.ultsonch.2010.09.015 · Cited by 115 · see citing works
Self-citationOlagunju, A. I., Omoba, O. S., Enujiugha, V. N., Alashi, A. M., & Aluko, R. E. (2018) · LWT · doi:10.1016/j.lwt.2018.07.003 · Cited by 114 · see citing works
Ultrasonic Degradation of Polysaccharide from a Red Algae (Porphyra yezoensis)
Zhou, C., & Ma, H. (2006) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf052763h · Cited by 112 · see citing works
Interfacial properties and structural conformation of thermosonicated bovine serum albumin
Güzey, D., Gülseren, İ., Bruce, B. D., & WEISS, J. (2005) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2005.06.008 · Cited by 111 · see citing works
Wong, F., Xiao, J., Ong, M. G.-L., Pang, M.-J., Wong, S.-J., Teh, L. K., & Chai, T. (2018) · Food Chemistry · doi:10.1016/j.foodchem.2018.07.206 · Cited by 110 · see citing works
Chen, C.-L., Liou, S., Chen, S.-J., & Shih, M. (2011) · Regulatory Toxicology and Pharmacology · doi:10.1016/j.yrtph.2011.03.001 · Cited by 101 · see citing works
Green Tea Polyphenols Inhibit Oxidant-Induced DNA Strand Breakage in Cultured Lung Cells
Leanderson, P., Faresjö, Å., & Tagesson, C. (1997) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(96)00590-4 · Cited by 98 · see citing works
Hsu, C., & Tain, Y. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20030681 · Cited by 98 · see citing works
Zou, T.-B., Xia, E.-Q., He, T.-P., Huang, M.-Y., Jia, Q., & Li, H.-W. (2014) · Molecules · doi:10.3390/molecules19021411 · Cited by 92 · see citing works
Self-citationCorrochano, A. R., Sariçay, Y., Arranz, E., Kelly, P. M., Buckin, V. A., & Giblin, L. M. (2018) · Journal of Dairy Science · doi:10.3168/jds.2018-14581 · Cited by 92 · see citing works
Lee, S. H., Kang, H. J., Lee, H., Kang, M., & Park, Y. K. (2009) · Nutrition · doi:10.1016/j.nut.2009.03.010 · Cited by 87 · see citing works
Evaluation of the antioxidant activity of extracellular polysaccharides from Morchella esculenta
Fu, L., Wang, Y., Wang, J., Yang, Y., & Hao, L. (2013) · Food & Function · doi:10.1039/c3fo60033e · Cited by 80 · see citing works
Sui, Y., Muys, M., Vermeir, P., D’Adamo, S., & Vlaeminck, S. E. (2018) · Bioresource Technology · doi:10.1016/j.biortech.2018.12.046 · Cited by 79 · see citing works
Guo, X., Shang, X., Xuzheng, Z., Zhao, B., & Zhang, J. (2017) · Ultrasonics Sonochemistry · doi:10.1016/j.ultsonch.2017.03.021 · Cited by 70 · see citing works
He, M., Zeng, J., Zhai, L., Liu, Y., Wu, H., Zhang, R., Li, Z., & Xia, E.-Q. (2017) · Food Research International · doi:10.1016/j.foodres.2017.10.001 · Cited by 68 · see citing works
Self-citationSannasimuthu, A., Kumaresan, V., Pasupuleti, M., Paray, B. A., Al‐Sadoon, M. K., & Arockiaraj, J. (2018) · Algal Research · doi:10.1016/j.algal.2018.09.028 · Cited by 64 · see citing works
Lin, Y., Wu, P., Tsai, Y., Hsu, Y., Wang, H. Y., Kuo, M., Kuo, P., & Hwang, S. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8020191 · Cited by 56 · see citing works
Narváez-Rivas, M., Vu, N., Chen, G., & Zhang, Q. (2016) · Analytica Chimica Acta · doi:10.1016/j.aca.2016.12.003 · Cited by 45 · see citing works
Kim, E., Hwang, J.-W., Kim, Y.-S., Ahn, C., Jeon, Y., Kweon, H.-J., Bahk, Y. Y., Moon, S.-H., Jeon, B.-T., & Park, P. (2012) · Process Biochemistry · doi:10.1016/j.procbio.2012.10.016 · Cited by 35 · see citing works
Leeb, E., Holder, A., Letzel, T., Cheison, S. C., Kulozik, U., & Hinrichs, J. (2014) · International Dairy Journal · doi:10.1016/j.idairyj.2013.12.006 · Cited by 26 · see citing works
Shan, J., Qian, W., An, K., Peng, L., Xie, T., Lin, L., Di, L., Xiao, P., & Zhou, W. (2018) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2018.09.037 · Cited by 20 · see citing works
Arun, N., & Singh, D. P. (2013) · Journal of the Marine Biological Association of India · doi:10.6024/jmbai.2013.55.1.01758-11 · Cited by 15 · see citing works
Ren, G., Hao, Y., Zhu, Y., Shi, Z., & Zhao, G. (2018) · Molecules · doi:10.3390/molecules23092373 · Cited by 14 · see citing works
Zou, Z., Cai, J., Zhong, A., Zhou, Y., Wang, Z., Wu, Z., Yang, Y. J., Li, X., Cheng, X., Tan, J., et al. (2018) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2018.11.014 · Cited by 12 · see citing works
Yuan, H., Meng, X., Gao, Q., Qu, W., Xu, T., Xu, Z., & Song, R. (2011) · Plant Cell Reports · doi:10.1007/s00299-011-1060-8 · Cited by 10 · see citing works
Mishra, A., & Jha, B. (2011) · Botanica Marina · doi:10.1515/bot.2011.011 · Cited by 7 · see citing works
Isolation and characterization of peroxiredoxin 1 gene of Dunaliella salina
Gong, F., Wang, J., & Li, J. (2017) · Gene · doi:10.1016/j.gene.2017.09.018 · Cited by 4 · see citing works
Yokthongwattana, K., Sriariyanun, M., Ekaratcharoenchai, P., & Svasti, J. (2009) · Journal of Applied Phycology · doi:10.1007/s10811-009-9434-9 · Cited by 1 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Bioactive peptides derived from marine sources: Biological and functional properties
Cunha, S. A., & Pintado, M. (2021) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2021.08.017 · Cited by 261 · see citing works
Recent developments on production, purification and biological activity of marine peptides
Sridhar, K., Inbaraj, B. S., & Chen, B. (2021) · Food Research International · doi:10.1016/j.foodres.2021.110468 · Cited by 131 · see citing works
Bioactivity of Marine-Derived Peptides and Proteins: A Review
Shahidi, F., & Saeid, A. (2025) · Marine Drugs · doi:10.3390/md23040157 · Cited by 112 · see citing works
Aondona, M. M., Ikya, J. K., Ukeyima, M. T., Gborigo, T. J. A., Aluko, R. E., & Girgih, A. T. (2020) · Journal of Food Biochemistry · doi:10.1111/jfbc.13587 · Cited by 89 · see citing works
Insights into Bioactive Peptides in Cosmetics
Ngoc, L. T. N., Moon, J., & Lee, Y. (2023) · Cosmetics · doi:10.3390/cosmetics10040111 · Cited by 91 · see citing works
Identification of antioxidant peptides from cheddar cheese made with Lactobacillus helveticus
Yang, W., Hao, X., Zhang, X., Zhang, G., Li, X., Liu, L., Sun, Y., & Pan, Y. (2021) · LWT · doi:10.1016/j.lwt.2021.110866 · Cited by 64 · see citing works
Derbel, H., Elleuch, J., Mahfoudh, W., Michaud, P., Fendri, I., & Abdelkafi, S. (2023) · Applied Sciences · doi:10.3390/app13053202 · Cited by 66 · see citing works
Beltrán, J. M. G., Arizcún, M., & Chaves-Pozo, E. (2023) · Marine Drugs · doi:10.3390/md21050290 · Cited by 56 · see citing works
Xing, L., Wang, Z., Hao, Y., & Zhang, W. (2022) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.1c07868 · Cited by 56 · see citing works
A Systemic Review on Microalgal Peptides: Bioprocess and Sustainable Applications
Sathya, R., MubarakAli, D., MohamedSaalis, J., & Kim, J.-W. (2021) · Sustainability · doi:10.3390/su13063262 · Cited by 48 · see citing works
Guzmán-Lorite, M., Marina, M. L., & García, M. C. (2022) · Innovative Food Science & Emerging Technologies · doi:10.1016/j.ifset.2022.102958 · Cited by 47 · see citing works
Castro, V., Oliveira, R., & Dias, A. C. P. (2023) · Algal Research · doi:10.1016/j.algal.2023.103287 · Cited by 40 · see citing works
Microalgae-Derived Peptides: Exploring Bioactivities and Functional Food Innovations
Ashraf, A., Guo, Y., Yang, T., ud Din, A. S., Ahmad, K., Li, W., & Hou, H. (2025) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.4c06800 · Cited by 32 · see citing works
Self-citationRai, A., Khan, M. J., Ahirwar, A., Deka, R., Singh, N. K., Schoefs, B., Marchand, J., Varjani, S., & Vinayak, V. (2022) · International Journal of Hydrogen Energy · doi:10.1016/j.ijhydene.2022.01.057 · Cited by 31 · see citing works
Zhou, J., Wei, M., & You, L. (2023) · Antioxidants · doi:10.3390/antiox12020535 · Cited by 29 · see citing works
Terriente-Palacios, C., Rubiño, S., Hortos, M., Peteiro, C., & Castellari, M. (2022) · Scientific Reports · doi:10.1038/s41598-022-25130-4 · Cited by 29 · see citing works
New perspectives on fabrication of peptide-based nanomaterials in food industry: A review
Chen, H., Chen, X., Chen, X., Lin, S. H., Cheng, J., You, L., Xiong, C., Cai, X., & Wang, S. (2022) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2022.09.004 · Cited by 26 · see citing works
Wasunan, P., Maneewong, C., Daengprok, W., & Thirabunyanon, M. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.892945 · Cited by 24 · see citing works
Bai, R., Nguyen, T. T., Zhou, Y., Diao, Y., & Zhang, W. (2023) · Marine Drugs · doi:10.3390/md21030146 · Cited by 22 · see citing works
Antiaging Potential of Peptides from Underused Marine Bioresources
Xia, E.-Q., Zhu, X., Gao, X., Ni, J., & Guo, H. (2021) · Marine Drugs · doi:10.3390/md19090513 · Cited by 22 · see citing works
Self-citationAbdo, A. A. A., Al‐Dalali, S., Hou, Y., Aleryani, H., Shehzad, Q., Asawmahi, O., AL-Farga, A. M., Mohammed, B. M., Liu, X., & Sang, Y. (2023) · Food and Bioprocess Technology · doi:10.1007/s11947-023-03142-w · Cited by 22 · see citing works
Ejike, C. E. C. C., Ezeorba, T. P. C., Ajah, O., & Udenigwe, C. C. (2023) · Global Challenges · doi:10.1002/gch2.202200162 · Cited by 20 · see citing works
MubarakAli, D., Akshaya, T., Raghunathan, S., & Navabshan, I. (2021) · Applied Biochemistry and Biotechnology · doi:10.1007/s12010-021-03716-4 · Cited by 21 · see citing works
Wang, L., Wang, L., Liu, X., Lin, X., Tao, F., & Zhang, W. (2025) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2025.2449596 · Cited by 18 · see citing works
Şahingil, D., Gokce, Y., & Hayaloğlu, A. A. (2023) · Journal of Food Science and Technology · doi:10.1007/s13197-023-05846-5 · Cited by 16 · see citing works
González-Osuna, M. F., Torres‐Arreola, W., Márquez‐Ríos, E., Wong‐Corral, F. J., Lugo‐Cervantes, E., Rodríguez-Figueroa, J. C., García‐Sánchez, G., Ezquerra‐Brauer, J. M., Soto‐Valdez, H., Castillo, A., et al. (2023) · Horticulturae · doi:10.3390/horticulturae9040415 · Cited by 11 · see citing works
Yin, X., Yang, Z., Shi, W., Fan, S., Guan, X., Ren, Y., Zhao, H., Fan, J., Wang, M., & Li, J. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.138573 · Cited by 10 · see citing works
Mousaie, M., Khodadadi, M., & Tadayoni, M. (2022) · Journal of Food Processing and Preservation · doi:10.1111/jfpp.17020 · Cited by 10 · see citing works
Carrillo, M., & Anchundia, M. (2024) · CABI Agriculture and Bioscience · doi:10.1186/s43170-024-00316-0 · Cited by 10 · see citing works
Defatted Nannochloropsis oculata biomass – Waste or resource?
Sousa, S. C., Machado, M., Coscueta, E. R., Ferreira, A. S., Nunes, C., Coimbra, M. A., Freitas, A. C., CARVALHO, A. P. F. D., & Gomes, A. (2024) · Algal Research · doi:10.1016/j.algal.2024.103695 · Cited by 6 · see citing works
Al-Khayri, J. M., Asghar, W., Khan, S., Akhtar, A., Ayub, H., Khalid, N., Alessa, F. M., Al-Mssallem, M. Q., Adel Abdel-Sabour, R. E. Z. K., & Shehata, W. F. (2022) · Marine Drugs · doi:10.3390/md20080477 · Cited by 6 · see citing works
Khaliq, M., Noor, Z., Moazzam, M., Saeed, F., Tul-Zohra, K., Tariq, E., Muhammad Shahbaz, H., & Khaliq, K. (2026) · Annals of Medicine · doi:10.1080/07853890.2026.2637282 · Cited by 4 · see citing works
“Similarly, peptides from Dunaliella salina (Chlorophyta) (e.g. ILTKAAIEGK, IIYFQGK) and Nannochloropsis oculata (GMNNLTP, LEQ) have demonstrated antioxidant and ACE inhibitory effects relevant to blood pressure regulation, respectively [63,67].”
Sbeghen, A. L., Lira, A. L., Fernandes, I. A., Steffens, C., Brião, V. B., Zeni, J., & Steffens, J. (2022) · Journal of Food Process Engineering · doi:10.1111/jfpe.14151 · Cited by 4 · see citing works
Krobthong, S., Jaroenchuensiri, T., Yingchutrakul, Y., Sukmak, P., Visessanguan, W., Pongkorpsakol, P., Tulyananda, T., & Aonbangkhen, C. (2024) · Foods · doi:10.3390/foods13152467 · Cited by 3 · see citing works
Marine antioxidants from microalgae
Khavari, F., Asadi, F., Nouri, F., Taheri, M., Mohammadi, F., Mohammadi, M., Habibi, P., & Asghari, B. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-95086-2.00009-6 · Cited by 3 · see citing works
Chua, L. S., Abdullah, F. I., Lim, T. K., & Lin, Q. (2023) · Food Chemistry · doi:10.1016/j.foodchem.2023.137261 · Cited by 3 · see citing works
Osama, H. M., Awady, M. E. E., Khalil, R., Farrag, A. A., Hamed, A. A., & Nasr-Eldin, M. A. (2025) · Scientific Reports · doi:10.1038/s41598-025-31348-9 · Cited by 2 · see citing works
Culețu, A., Kreische, M., Schweikert, T., Henze, A., & Sagu, S. T. (2026) · Food Chemistry · doi:10.1016/j.foodchem.2026.148081 · Cited by 3 · see citing works
Sahadevan, S., Liow, M. Y., Mahendra, C. K., Ng, W. Z., Chan, E., Borhan, N., Yahya, L., Bakri, F. A. M., Japar, A. S., Chan, W., et al. (2026) · Phytochemistry Reviews · doi:10.1007/s11101-026-10247-5 · Cited by 2 · see citing works
Akbari, P., Gholamhosseini, A., Ali, M., Aminikhoei, Z., Tavabe, K. R., & Kuchaksaraei, B. S. (2022) · Iranian Journal of Science · doi:10.1007/s40995-022-01396-1 · Cited by 2 · see citing works
Marine algal carbohydrate and peptide antioxidants
Mishra, P. K., Chatterjee, S., Gautam, R. K., Kakatkar, A. S., & Kumar, V. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-95086-2.00008-4 · Cited by 2 · see citing works
Goh, P. K., Liow, M. Y., Ng, W. Z., Chan, E., Borhan, N., Yahya, L., Bakri, F. A. M., Japar, A. S., Chan, W., Shukor, M. S. M., et al. (2026) · Separation and Purification Technology · doi:10.1016/j.seppur.2026.138743 · Cited by 1 · see citing works
Zhang, R., Yin, L., Chen, J., & Zhang, X. (2020) · Food Technology and Biotechnology · doi:10.17113/ftb.58.04.20.6657
Szewczyk, R. (2025) · Engineering Sciences And Technologies · doi:10.15611/nit.2025.41.04
- Authors
- Xia, E., Zhai, L., Huang, Z., Liang, H., Yang, H., Song, G., Li, W., & Tang, H.
- Affiliations
- Dongguan Key Laboratory of Environmental Medicine, School of Public Health, Guangdong Medical University, Dongguan 523808, China
- Guangdong Medical College (CN)
- Corresponding author
- Tang, Huanwen
- Venue
- BioMed Research International
- Publisher
- Wiley
- Published
- 2019-08-20
- Volume
- 2019
- Pages
- 1-9
- ISSN
- 1110-7243 (ISSN-L)
- 2314-6133
- 2314-6141
- PMC
- PMC6720044
- OpenAlex
- W2969964596
- Cited by
- 44
- References
- 45
- Citations by year
- 2026: 4 · 2025: 5 · 2024: 4 · 2023: 13 · 2022: 10 · 2021: 6 · 2020: 2
- FWCI
- 1.49
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Locations
- BioMed Research International (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Key Laboratories Project of Universities in Guangdong Province (2015KTSCX052, 4SG18102G, 4SG18004G, 4SG18056G, 4SG17043, 2KY17018)
- Provincial-Municipal Co-construction Projects of Guangdong Province (2015KTSCX052, 4SG18102G, 4SG18004G, 4SG18056G, 4SG17043, 2KY17018)
- Innovative Experimental Project for College Students of Guangdong Medical University (2015KTSCX052, 4SG18102G, 4SG18004G, 4SG18056G, 4SG17043, 2KY17018)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Hydrolysis and Bioactive Peptides
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Life Sciences › Agricultural and Biological Sciences › Food Science › Proteins in Food Systems
- Keywords
- antioxidant peptides, Dunaliella salina, algae proteins, DPPH radical scavenging, ultrasound-assisted extraction, in vitro digestion, peptide fractionation, membrane ultrafiltration, hydrophobic residues
- MeSH terms
- Chlorophyceae, Antioxidants, Biphenyl Compounds, Gastric Juice, Peptides, Picrates, Proteins, Microalgae
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
