Bioactivity of Marine-Derived Peptides and Proteins: A Review

Inflammatory responses and inflammation-associated diseases in organs

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Collagen in Wound Healing

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Oxidative stress mitigation by antioxidants - An overview on their chemistry and influences on health status

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Marketed Marine Natural Products in the Pharmaceutical and Cosmeceutical Industries: Tips for Success

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Antioxidant peptides from marine by-products: Isolation, identification and application in food systems. A review

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Plant protein-derived antioxidant peptides: Isolation, identification, mechanism of action and application in food systems: A review

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The development of collagen based composite scaffolds for bone regeneration

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Marine Peptides: Bioactivities and Applications

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Antimicrobial Peptides from Fish

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Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A

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Marine Collagen as A Promising Biomaterial for Biomedical Applications

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Extending the “One Strain Many Compounds” (OSMAC) Principle to Marine Microorganisms

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Fish viscera protein hydrolysates: Production, potential applications and functional and bioactive properties

Villamil, O., Váquiro, H., & Solanilla, J. F. (2017) · Food Chemistry · doi:10.1016/j.foodchem.2016.12.057 · Cited by 310 · see citing works

Peptides from Fish By-product Protein Hydrolysates and Its Functional Properties: an Overview

Zamora-Sillero, J., Gharsallaoui, A., & Prentice, C. (2018) · Marine Biotechnology · doi:10.1007/s10126-018-9799-3 · Cited by 276 · see citing works

Marine Collagen Peptides from the Skin of Nile Tilapia (Oreochromis niloticus): Characterization and Wound Healing Evaluation

Hu, Z., Yang, P., Zhou, C., Li, S., & Hong, P. (2017) · Marine Drugs · doi:10.3390/md15040102 · Cited by 265 · see citing works

Bioactive peptides derived from marine sources: Biological and functional properties

Cunha, S. A., & Pintado, M. (2021) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2021.08.017 · Cited by 261 · see citing works

Marine Fish Proteins and Peptides for Cosmeceuticals: A Review

Venkatesan, J., Anil, S., Kim, S., & Shim, M. S. (2017) · Marine Drugs · doi:10.3390/md15050143 · Cited by 260 · see citing works

Innovative Green Technologies of Intensification for Valorization of Seafood and Their By-Products

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Production and processing of antioxidant bioactive peptides: A driving force for the functional food market

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Marine Collagen: A Promising Biomaterial for Wound Healing, Skin Anti-Aging, and Bone Regeneration

Geahchan, S., Baharlouei, P., & Rahman, M. A. (2022) · Marine Drugs · doi:10.3390/md20010061 · Cited by 250 · see citing works

Purification and anti-inflammatory action of tripeptide from salmon pectoral fin byproduct protein hydrolysate

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Phycobiliproteins: Structural aspects, functional characteristics, and biotechnological perspectives

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Cosmetic Potential of Marine Fish Skin Collagen

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Collagen Hydrolysates for Skin Protection: Oral Administration and Topical Formulation

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Extraction and characterization of acid soluble collagen from fish waste: Development of collagen-chitosan blend as food packaging film

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Cosmetic, Biomedical and Pharmaceutical Applications of Fish Gelatin/Hydrolysates

Al‐Nimry, S. S., Dayah, A. A., Hasan, I., & Daghmash, R. M. (2021) · Marine Drugs · doi:10.3390/md19030145 · Cited by 214 · see citing works

Purification and characterization of novel antioxidant peptides from enzymatic hydrolysates of tilapia (Oreochromis niloticus) skin gelatin

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Purification and identification of dipeptidyl peptidase (DPP) IV inhibitory peptides from the macroalga Palmaria palmata

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Selective Extraction of Collagen Peptides with High Purity from Cod Skins by Deep Eutectic Solvents

Bai, C., Wei, Q., & Ren, X. (2017) · ACS Sustainable Chemistry & Engineering · doi:10.1021/acssuschemeng.7b01439 · Cited by 193 · see citing works

Bioactive peptides in cereals and legumes: agronomical, biochemical and clinical aspects.

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Marine bioactive compounds and health promoting perspectives; innovation pathways for drug discovery

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Identification of Bioactive Peptides with α-Amylase Inhibitory Potential from Enzymatic Protein Hydrolysates of Red Seaweed (Porphyra spp)

Admassu, H., Gasmalla, M. A. A., Yang, R., & Zhao, W. (2018) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.8b00960 · Cited by 178 · see citing works

Bioactive peptides from shrimp shell processing discards: Antioxidant and biological activities

Ambigaipalan, P., & Shahidi, F. (2017) · Journal of Functional Foods · doi:10.1016/j.jff.2017.04.013 · Cited by 171 · see citing works

Fucoxanthin, a Marine-Derived Carotenoid from Brown Seaweeds and Microalgae: A Promising Bioactive Compound for Cancer Therapy

Méresse, S., Fodil, M., Fleury, F., & Chénais, B. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21239273 · Cited by 171 · see citing works

Encyclopedia of Marine Biotechnology

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A Review of Protein Hydrolysates and Bioactive Peptides Deriving from Wastes Generated by Fish Processing

Ishak, N. H., & Sarbon, N. M. (2017) · Food and Bioprocess Technology · doi:10.1007/s11947-017-1940-1 · Cited by 163 · see citing works

Antimicrobial and Immunomodulatory Properties and Applications of Marine-Derived Proteins and Peptides

Kang, H., Lee, H., Seo, C., & Park, Y. (2019) · Marine Drugs · doi:10.3390/md17060350 · Cited by 161 · see citing works

Northern Sea Cucumber (Cucumaria frondosa): A Potential Candidate for Functional Food, Nutraceutical, and Pharmaceutical Sector

Hossain, A., Dave, D., & Shahidi, F. (2020) · Marine Drugs · doi:10.3390/md18050274 · Cited by 159 · see citing works

Fish Collagen Surgical Compress Repairing Characteristics on Wound Healing Process In Vivo

Chen, J., Gao, K., Liu, S., Wang, S., Elango, J., Bao, B., Dong, J., Liu, N., & Wu, W. (2019) · Marine Drugs · doi:10.3390/md17010033 · Cited by 154 · see citing works

Basic and recent advances in marine antihypertensive peptides: Production, structure-activity relationship and bioavailability

Abdelhedi, O., & Nasri, M. (2019) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2019.04.002 · Cited by 153 · see citing works

Fractionation and identification of antioxidant peptides from an enzymatically hydrolysed Palmaria palmata protein isolate

Harnedy, P. A., O’Keeffe, M. B., & Fitzgerald, R. J. (2017) · Food Research International · doi:10.1016/j.foodres.2017.07.037 · Cited by 152 · see citing works

Peptide identification in a salmon gelatin hydrolysate with antihypertensive, dipeptidyl peptidase IV inhibitory and antioxidant activities

Neves, A. C., Harnedy, P. A., O’Keeffe, M. B., Alashi, M. A., Aluko, R. E., & Fitzgerald, R. J. (2017) · Food Research International · doi:10.1016/j.foodres.2017.06.065 · Cited by 150 · see citing works

Identification of anti-diabetes peptides from Spirulina platensis

Hu, S., Fan, X., Qi, P., & Zhang, X. (2019) · Journal of Functional Foods · doi:10.1016/j.jff.2019.03.024 · Cited by 150 · see citing works

Isolation, characterization and valorizable applications of fish scale collagen in food and agriculture industries

Bhagwat, P. K., & Dandge, P. B. (2016) · Biocatalysis and Agricultural Biotechnology · doi:10.1016/j.bcab.2016.06.010 · Cited by 149 · see citing works

Antioxidant peptides from protein hydrolysate of skipjack tuna milt: Purification, identification, and cytoprotection on H2O2 damaged human umbilical vein endothelial cells

Wang, Y., Li, X., Wang, J., He, Y. T., Chi, C., & Wang, B. (2022) · Process Biochemistry · doi:10.1016/j.procbio.2022.01.008 · Cited by 149 · see citing works

Bioactivities of fish protein hydrolysates from defatted salmon backbones

Šližytė, R., Rommi, K., Mozūraitytė, R., Eck, P., Five, K. K., & Rustad, T. (2016) · Biotechnology Reports · doi:10.1016/j.btre.2016.08.003 · Cited by 146 · see citing works

Gastrointestinal and cardiovascular adverse events associated with NSAIDs

Domper-Arnal, M. J., Hijos, G., & Lanas, Á. (2021) · Expert Opinion on Drug Safety · doi:10.1080/14740338.2021.1965988 · Cited by 143 · see citing works

Preparation and Identification of ACE Inhibitory Peptides from the Marine Macroalga Ulva intestinalis

Sun, S., Xu, X., Sun, X., Zhang, X., Chen, X., & Xu, N. (2019) · Marine Drugs · doi:10.3390/md17030179 · Cited by 140 · see citing works

Current knowledge on the extraction, purification, identification, and validation of bioactive peptides from seaweed

Cermeño, M., Kleekayai, T., Amigo‐Benavent, M., Harnedy‐Rothwell, P. A., & Fitzgerald, R. J. (2020) · Electrophoresis · doi:10.1002/elps.202000153 · Cited by 139 · see citing works

Microalgae, a Potential Natural Functional Food Source – a Review

Villarruel‐López, A., Ascencio, F., & Nuño, K. (2017) · Polish Journal of Food and Nutrition Sciences · doi:10.1515/pjfns-2017-0017 · Cited by 138 · see citing works

Novel Antioxidant Collagen Peptides of Siberian Sturgeon (Acipenserbaerii) Cartilages: The Preparation, Characterization, and Cytoprotection of H2O2-Damaged Human Umbilical Vein Endothelial Cells (HUVECs)

Sheng, Y., Qiu, Y., Wang, Y., Chi, C., & Wang, B. (2022) · Marine Drugs · doi:10.3390/md20050325 · Cited by 138 · see citing works

Extraction of Protein from Four Different Seaweeds Using Three Different Physical Pre-Treatment Strategies

Connor, J. O., Meaney, S., Williams, G. A., & Hayes, M. (2020) · Molecules · doi:10.3390/molecules25082005 · Cited by 136 · see citing works

Marine Organisms as a Rich Source of Biologically Active Peptides

Macedo, M. W. F. S., da Cunha, N. B., Carneiro, J. A., da Costa, R. A., de Alencar, S. A., Cardoso, M. H. E. S., Franco, O. L., & Dias, S. C. (2021) · Frontiers in Marine Science · doi:10.3389/fmars.2021.667764 · Cited by 136 · see citing works

Peptides, Peptidomimetics, and Polypeptides from Marine Sources: A Wealth of Natural Sources for Pharmaceutical Applications

Sable, R. V., Parajuli, P., & Jois, S. D. S. (2017) · Marine Drugs · doi:10.3390/md15040124 · Cited by 135 · see citing works

Generation of antioxidative peptides from Atlantic sea cucumber using alcalase versus trypsin: In vitro activity, de novo sequencing, and in silico docking for in vivo function prediction

Zhang, Y., He, S., Bonneil, É., & Simpson, B. K. (2019) · Food Chemistry · doi:10.1016/j.foodchem.2019.125581 · Cited by 135 · see citing works

Seventeen novel angiotensin converting enzyme (ACE) inhibitory peptides from the protein hydrolysate of Mytilus edulis : isolation, identification, molecular docking study, and protective function on HUVECs

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Atlantic salmon (Salmo salar) co-product-derived protein hydrolysates: A source of antidiabetic peptides

Harnedy, P. A., Parthsarathy, V., McLaughlin, C. M., O’Keeffe, M. B., Allsopp, P. J., McSorley, E. M., O'Harte, F. P. M., & Fitzgerald, R. J. (2018) · Food Research International · doi:10.1016/j.foodres.2018.01.025 · Cited by 132 · see citing works

The Neuroendocrine-Immune Regulation in Response to Environmental Stress in Marine Bivalves

Liu, Z., Li, M., Yi, Q., Wang, L., & Song, L. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.01456 · Cited by 132 · see citing works

Recent developments on production, purification and biological activity of marine peptides

Sridhar, K., Inbaraj, B. S., & Chen, B. (2021) · Food Research International · doi:10.1016/j.foodres.2021.110468 · Cited by 131 · see citing works

Seaweeds, an aquatic plant-based protein for sustainable nutrition - A review

Raja, K., Kadirvel, V., & Thiruvengadam, S. (2022) · Future Foods · doi:10.1016/j.fufo.2022.100142 · Cited by 130 · see citing works

Production of fish protein hydrolysates step by step: technological aspects, equipment used, major energy costs and methods of their minimizing

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Quality parameters of frankfurter-type sausages with partial replacement of fat by hydrolyzed collagen

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Peptide identification from a Porphyra dioica protein hydrolysate with antioxidant, angiotensin converting enzyme and dipeptidyl peptidase IV inhibitory activities

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Effect of collagen-lysozyme coating on fresh-salmon fillets preservation

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Production and identification of dipeptidyl peptidase IV (DPP-IV) inhibitory peptides from discarded Sardine pilchardus protein

Rivero‐Pino, F., Espejo-Carpio, F. J., & Guadix, E. M. (2020) · Food Chemistry · doi:10.1016/j.foodchem.2020.127096 · Cited by 116 · see citing works

Gelatins and antioxidant peptides from Skipjack tuna (Katsuwonus pelamis) skins: Purification, characterization, and cytoprotection on ultraviolet-A injured human skin fibroblasts

Zhang, S.-Y., Zhao, Y., Wang, Y., Yang, X., Chi, C., & Wang, B. (2022) · Food Bioscience · doi:10.1016/j.fbio.2022.102138 · Cited by 112 · see citing works

Angiotensin-I-Converting Enzyme (ACE)-Inhibitory Peptides from the Collagens of Monkfish (Lophius litulon) Swim Bladders: Isolation, Characterization, Molecular Docking Analysis and Activity Evaluation

Hu, Y., Xi, Q.-H., Kong, J., Zhao, Y., Chi, C., & Wang, B. (2023) · Marine Drugs · doi:10.3390/md21100516 · Cited by 110 · see citing works

Proteins and bioactive peptides from algae: insights into antioxidant, anti-hypertensive, anti-diabetic and anti-cancer activities

Leong, Y. K., & Chang, J.-S. (2024) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2024.104352 · Cited by 109 · cited 3× · see citing works

A novel anticoagulant peptide from the Nori hydrolysate

Indumathi, P., & Mehta, A. (2015) · Journal of Functional Foods · doi:10.1016/j.jff.2015.11.016 · Cited by 106 · see citing works

Ten new pentapeptides from protein hydrolysate of miiuy croaker (Miichthys miiuy) muscle: Preparation, identification, and antioxidant activity evaluation

He, Y. T., Pan, X. Y., Chi, C., Sun, K., & Wang, B. (2019) · LWT · doi:10.1016/j.lwt.2019.01.054 · Cited by 106 · see citing works

Comparisons of protective effects between two sea cucumber hydrolysates against diet induced hyperuricemia and renal inflammation in mice

Wan, H., Han, J., Tang, S., Bao, W., Lu, C., Zhou, J., Ming, T., Li, Y., & Su, X. (2019) · Food & Function · doi:10.1039/c9fo02425e · Cited by 105 · see citing works

Identification and characterisation of peptides from a boarfish (Capros aper) protein hydrolysate displaying in vitro dipeptidyl peptidase-IV (DPP-IV) inhibitory and insulinotropic activity

Harnedy‐Rothwell, P. A., McLaughlin, C. M., O’Keeffe, M. B., Gouic, A. V. L., Allsopp, P. J., McSorley, E. M., Sharkey, S. J., Whooley, J., McGovern, B., O'Harte, F. P. M., et al. (2020) · Food Research International · doi:10.1016/j.foodres.2020.108989 · Cited by 105 · see citing works

Marine Algae Extracts

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Isolation, purification and identification of three novel antioxidative peptides from patin (Pangasius sutchi) myofibrillar protein hydrolysates

Najafian, L., & Babji, A. S. (2014) · LWT · doi:10.1016/j.lwt.2014.07.046 · Cited by 103 · see citing works

Bioactivity and bioaccessibility of protein hydrolyzates from industrial byproducts of Stripped weakfish (Cynoscion guatucupa)

Lima, K. O., de Quadros, C. D. C., da Rocha, M., Lacerda, J. T., Juliano, M. A., Dias, M., Mendes, M. A., & Prentice, C. (2019) · LWT · doi:10.1016/j.lwt.2019.05.043 · Cited by 103 · see citing works

Marine Bioactive Peptides—An Overview of Generation, Structure and Application with a Focus on Food Sources

Pavlićević, M., Maestri, E., & Marmiroli, M. (2020) · Marine Drugs · doi:10.3390/md18080424 · Cited by 102 · see citing works

Purification and identification of anti-obesity peptides derived from Spirulina platensis

Fan, X., Cui, Y., Zhang, R., & Zhang, X. (2018) · Journal of Functional Foods · doi:10.1016/j.jff.2018.05.066 · Cited by 100 · see citing works

Fish collagen peptide inhibits the adipogenic differentiation of preadipocytes and ameliorates obesity in high fat diet-fed mice.

Lee, E. J., Hur, J., Ham, S. A., Jo, Y., Lee, S., Choi, M.-J., & Seo, H. (2017) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2017.05.151 · Cited by 97 · see citing works

Therapeutic Properties and Biological Benefits of Marine-Derived Anticancer Peptides

Kang, H. K., Choi, M., Seo, C., & Park, Y. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19030919 · Cited by 97 · see citing works

Supercritical CO2 and subcritical water technologies for the production of bioactive extracts from sardine (Sardina pilchardus) waste

Melgosa, R., Trigueros, E., Sanz, M. T., Cardeira, M., Rodrigues, L. A., Fernández, N., Matias, A. A., Bronze, M. R., Marques, M., Paiva, A., et al. (2020) · The Journal of Supercritical Fluids · doi:10.1016/j.supflu.2020.104943 · Cited by 97 · see citing works

Evaluation of astaxanthin incorporated collagen film developed from the outer skin waste of squid Doryteuthis singhalensis for wound healing and tissue regenerative applications

Veeruraj, A., Liu, L., Zheng, J., Wu, J., & Arumugam, M. (2018) · Materials Science and Engineering C · doi:10.1016/j.msec.2018.10.055 · Cited by 95 · see citing works

Purification and characterization of angiotensin converting enzyme-inhibitory peptides derived from Stichopus horrens : Stability study against the ACE and inhibition kinetics

Forghani, B., Zarei, M., Ebrahimpour, A., Philip, R., Bakar, J., Hamid, A. A., & Saari, N. (2015) · Journal of Functional Foods · doi:10.1016/j.jff.2015.10.025 · Cited by 94 · see citing works

Elicited ROS Scavenging Activity, Photoprotective, and Wound-Healing Properties of Collagen-Derived Peptides from the Marine Sponge Chondrosia reniformis

Pozzolini, M., Millo, E., Oliveri, C., Mirata, S., Salis, A., Damonte, G., Arkel, M., & Scarfı̀, S. (2018) · Marine Drugs · doi:10.3390/md16120465 · Cited by 93 · see citing works

A review on marine collagen: sources, extraction methods, colloids properties, and food applications

Farooq, S., Ahmad, M. I., Zheng, S., Ali, U., Li, Y., Shixiu, C., & Zhang, H. (2024) · Collagen and Leather · doi:10.1186/s42825-024-00152-y · Cited by 93 · see citing works

Isolation and identification of anti‐proliferative peptides from Spirulina platensis using three‐step hydrolysis

Wang, Z., & Zhang, X. (2016) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.7815 · Cited by 92 · see citing works

Application of quantitative structure-activity relationship to food-derived peptides: Methods, situations, challenges and prospects

Bo, W., Chen, L., Qin, D., Geng, S., Li, J., Hu, M. Y., Li, B., & Liang, G. (2021) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2021.05.031 · Cited by 91 · see citing works

Production of Bioactive Peptides from Sea Cucumber and Its Potential Health Benefits: A Comprehensive Review

Lu, Z., Sun, N., Liu, D., Gao, Y., & Lin, S. (2022) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.2c02696 · Cited by 90 · see citing works

Identification and characterization of novel antioxidant peptides from mackerel (Scomber japonicus) muscle protein hydrolysates

Bashir, K. M. I., Sohn, J. H., Kim, J., & Choi, J. (2020) · Food Chemistry · doi:10.1016/j.foodchem.2020.126809 · Cited by 88 · see citing works

Protective effect of gelatin polypeptides from Pacific cod (Gadus macrocephalus) against UV irradiation-induced damages by inhibiting inflammation and improving transforming growth factor-β/Smad signaling pathway

Chen, T., & Hou, H. (2016) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2016.07.038 · Cited by 87 · see citing works

Preparation and Evaluation of Peptides with Potential Antioxidant Activity by Microwave Assisted Enzymatic Hydrolysis of Collagen from Sea Cucumber Acaudina Molpadioides Obtained from Zhejiang Province in China

Jin, H., Hongping, X., Li, Y., Zhang, Q.-W., & Xie, H. (2019) · Marine Drugs · doi:10.3390/md17030169 · Cited by 86 · see citing works

Spirulina platensis prevents hyperglycemia in rats by modulating gluconeogenesis and apoptosis via modification of oxidative stress and MAPK-pathways

Sadek, K. M., Lebda, M. A., Nasr, S. M., & Shoukry, M. (2017) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2017.06.023 · Cited by 84 · see citing works

Sturgeon protein-derived peptides exert anti-inflammatory effects in LPS-stimulated RAW264.7 macrophages via the MAPK pathway

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Coculture of Marine Streptomyces sp. With Bacillus sp. Produces a New Piperazic Acid-Bearing Cyclic Peptide

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From Life in the Sea to the Clinic: The Marine Drugs Approved and under Clinical Trial

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Antibacterial peptides from barbel muscle protein hydrolysates: Activity against some pathogenic bacteria

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Marine Biocompounds for Neuroprotection—A Review

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Collagen from Cartilaginous Fish By-Products for a Potential Application in Bioactive Film Composite

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Isolation of marine crab (Charybdis natator) leg muscle peptide and its anti-inflammatory effects on macrophage cells

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Release of antidiabetic peptides from Stichopus japonicas by simulated gastrointestinal digestion

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Marine Health-Promoting Compounds: Recent Trends for Their Characterization and Human Applications

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High Fischer ratio oligopeptides from hard-shelled mussel: Preparation and hepatoprotective effect against acetaminophen-induced liver injury in mice

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Neuroprotective Function of a Novel Hexapeptide QMDDQ from Shrimp via Activation of the PKA/CREB/BNDF Signaling Pathway and Its Structure–Activity Relationship

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Purification, Identification, Activity Evaluation, and Stability of Antioxidant Peptides from Alcalase Hydrolysate of Antarctic Krill (Euphausia superba) Proteins

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Anti-aging effect of sea cucumber (Cucumaria frondosa) hydrolysate on fruit flies and d-galactose-induced aging mice

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Immunomodulatory activity of low molecular-weight peptides from Nibea japonica skin in cyclophosphamide-induced immunosuppressed mice

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Preparation of Antioxidant Peptide by Microwave- Assisted Hydrolysis of Collagen and Its Protective Effect Against H2O2-Induced Damage of RAW264.7 Cells

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Collagen/zein electrospun films incorporated with gallic acid for tilapia (Oreochromis niloticus) muscle preservation

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Novel bioactive peptides from enzymatic hydrolysate of Sardinelle ( Sardinella aurita ) muscle proteins hydrolysed by Bacillus subtilis A26 proteases

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Marine proteins and peptides: Production, biological activities, and potential applications

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Identification and Antithrombotic Activity of Peptides from Blue Mussel (Mytilus edulis) Protein

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Screening for metabolic syndrome application of a herring by-product hydrolysate after its separation by electrodialysis with ultrafiltration membrane and identification of novel anti-inflammatory peptides

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Mechanism Analysis of a Novel Angiotensin-I-Converting Enzyme Inhibitory Peptide from Isochrysis zhanjiangensis Microalgae for Suppressing Vascular Injury in Human Umbilical Vein Endothelial Cells

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European chondroitin sulfate and glucosamine food supplements: A systematic quality and quantity assessment compared to pharmaceuticals

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Myticusin-beta, antimicrobial peptide from the marine bivalve, Mytilus coruscus

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Natural ACE inhibitory peptides discovery from Spirulina (Arthrospira platensis) strain C1

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Anticancer potential of natural peptides from terrestrial and marine environments: A review

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A Review on Purification and Characterization of Anti-proliferative Peptides Derived from Fish Protein Hydrolysate

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Antioxidant and Antimicrobial Enhancement by Reaction of Protein Hydrolysates Derived from Shrimp By-Products with Glucosamine

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High-degree hydrolysis sea cucumber peptides improve exercise performance and exert antifatigue effect via activating the NRF2 and AMPK signaling pathways in mice

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Identification and molecular mechanism of angiotensin-converting enzyme inhibitory peptides from Larimichthys crocea titin

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Investigation of Chlorella pyrenoidosa Protein as a Source of Novel Angiotensin I-Converting Enzyme (ACE) and Dipeptidyl Peptidase-IV (DPP-IV) Inhibitory Peptides

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Anticancer activities of natural antimicrobial peptides from animals

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Purification and antioxidant activities of peptides from sea squirt (Halocynthia roretzi) protein hydrolysates using pepsin hydrolysis

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Purification and Identification of Angiotensin I-Converting Enzyme Inhibitory Peptides and the Antihypertensive Effect of Chlorella sorokiniana Protein Hydrolysates

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Isolation and characterization of anti-inflammatory peptides derived from trypsin hydrolysis of microalgae protein ( Synechococcus sp. VDW)

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In Vitro Bioactivity of Astaxanthin and Peptides from Hydrolisates of Shrimp (Parapenaeus longirostris) By-Products: From the Extraction Process to Biological Effect Evaluation, as Pilot Actions for the Strategy “From Waste to Profit”

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Sea cucumber (Codonopsis pilosula) oligopeptides: immunomodulatory effects based on stimulating Th cells, cytokine secretion and antibody production

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Phycocyanin ameliorates alloxan-induced diabetes mellitus in mice: Involved in insulin signaling pathway and GK expression

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Bioactive Peptides from Marine Ascidians and Future Drug Development–A Review

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Identification and in silico study of a novel dipeptidyl peptidase IV inhibitory peptide derived from green seaweed Ulva spp. hydrolysates

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Antithrombotic properties of Spirulina extracts against platelet-activating factor and thrombin

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Cm-p5: an antifungal hydrophilic peptide derived from the coastal mollusk Cenchritis muricatus (Gastropoda: Littorinidae)

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Identification and inhibitory activity against α-thrombin of a novel anticoagulant peptide derived from oyster ( Crassostrea gigas ) protein

Cheng, S., Tu, M., Chen, H., Xu, Z., Wang, Z., Liu, H., Zhao, G., Zhu, B., & Du, M. (2018) · Food & Function · doi:10.1039/c8fo01635f · Cited by 51 · see citing works

Purification and identification of anti-allergic peptide from Atlantic Salmon (Salmo salar) byproduct enzymatic hydrolysates

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Valorisation of tuna processing waste biomass: isolation, purification and characterisation of four novel antioxidant peptides from tuna by-product hydrolysate

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Novel Fibrinolytic Protease Producing Streptomyces radiopugnans VITSD8 from Marine Sponges

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Production of enzymatic hydrolysates with in vitro antioxidant, antihypertensive, and antidiabetic properties from proteins derived from Arthrospira platensis

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A defensin from clam Venerupis philippinarum: Molecular characterization, localization, antibacterial activity, and mechanism of action

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Effect of Spirulina platensis ingestion on the abnormal biochemical and oxidative stress parameters in the pancreas and liver of alloxan-induced diabetic rats

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Bioinformatics Study of Sea Cucumber Peptides as Antibreast Cancer Through Inhibiting the Activity of Overexpressed Protein (EGFR, PI3K, AKT1, and CDK4)

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Anti-inflammatory action of two novel peptides derived from peanut worms ( Sipunculus nudus ) in lipopolysaccharide-induced RAW264.7 macrophages

Sangtanoo, P., Srimongkol, P., Saisavoey, T., Reamtong, O., & Karnchanatat, A. (2019) · Food & Function · doi:10.1039/c9fo02178g · Cited by 48 · see citing works

Purification, characterization and molecular docking study of angiotensin-I converting enzyme (ACE) inhibitory peptide from shortfin scad (Decapterus macrosoma) protein hydrolysate

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In vitro thrombolytic activity of a purified fibrinolytic enzyme from Chlorella vulgaris

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Preparation and Identification of Novel Antihypertensive Peptides from the In Vitro Gastrointestinal Digestion of Marine Cobia Skin Hydrolysates

Lin, Y.-H., Chen, C., Tsai, J., & Chen, G. (2019) · Nutrients · doi:10.3390/nu11061351 · Cited by 47 · see citing works

Octominin: A Novel Synthetic Anticandidal Peptide Derived from Defense Protein of Octopus minor

Nikapitiya, C., Dananjaya, S. H. S., Chandrarathna, H. P. S. U., Zoysa, M. D., & Whang, I. (2020) · Marine Drugs · doi:10.3390/md18010056 · Cited by 47 · see citing works

Thrombin inhibitory peptides derived from Mytilus edulis proteins: identification, molecular docking and in silico prediction of toxicity

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Effects of oral administration of peptides with low molecular weight from Alaska Pollock (Theragra chalcogramma) on cutaneous wound healing

Yang, T., Zhang, K., Li, B., & Hou, H. (2018) · Journal of Functional Foods · doi:10.1016/j.jff.2018.08.006 · Cited by 46 · see citing works

Characterizations and the Mechanism Underlying Osteogenic Activity of Peptides from Enzymatic Hydrolysates of Stichopus japonicus

Yang, M., Xu, Z., Wu, D., Dong, Y., Wang, Z., & Du, M. (2021) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.1c06028 · Cited by 46 · see citing works

An ACE inhibitory peptide from Isochrysis zhanjiangensis exhibits antihypertensive effect via anti-inflammation and anti-apoptosis in HUVEC and hypertensive rats

Pei, Y., Cai, S., Ryu, B., Zhou, C., Hong, P., & Qian, Z. (2022) · Journal of Functional Foods · doi:10.1016/j.jff.2022.105061 · Cited by 45 · see citing works

Optimization and Identification of Antioxidant Peptide from Underutilized<i> Dunaliella salina Protein</i>: Extraction,<i> In Vitro</i> Gastrointestinal Digestion, and Fractionation

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Isolation and Characterization of Antimicrobial Peptides with Unusual Disulfide Connectivity from the Colonial Ascidian Synoicum turgens

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Peptides Derived from Rhopilema esculentum Hydrolysate Exhibit Angiotensin Converting Enzyme (ACE) Inhibitory and Antioxidant Abilities

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Purification and characterization of two novel angiotensin I-converting enzyme inhibitory peptides derived from R-phycoerythrin of red algae (Bangia fusco-purpurea)

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Angiotensin Converting Enzyme and Dipeptidyl Peptidase-IV Inhibitory, and Antioxidant Activities of a Blue Mussel (Mytilus edulis) Meat Protein Extract and Its Hydrolysates

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Effect of angiotensin I-converting enzyme (ACE) inhibition and nitric oxide (NO) production of 6,6′-bieckol, a marine algal polyphenol and its anti-hypertensive effect in spontaneously hypertensive rats

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Isolation and identification of an angiotensin I-converting enzyme inhibitory peptide from pearl oyster (Pinctada fucata) shell protein hydrolysate

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Sea Cucumber-Derived Peptide Attenuates Scopolamine-Induced Cognitive Impairment by Preventing Hippocampal Cholinergic Dysfunction and Neuronal Cell Death

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Characterisation of Bioactive Peptides from Red Alga Gracilariopsis chorda

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A review on anti-inflammatory and antioxidant peptides derived from marine organisms: Mechanism of action and therapeutic applications

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Potential Antioxidant Properties of Enzymatic Hydrolysates from Stichopus japonicus against Hydrogen Peroxide-Induced Oxidative Stress

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An assessment of serum oxidative stress and antioxidant parameters in patients undergoing treatment for cervical cancer

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I dentification and molecular docking of novel ACE inhibitory peptides from protein hydrolysates of shrimp waste

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Effects of collagen peptides from skate ( Raja kenojei ) skin on improvements of the insulin signaling pathway via attenuation of oxidative stress and inflammation

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Preparation of sea cucumber (Stichopus variegates) peptide fraction with desired organoleptic property and its anti-aging activity in fruit flies and D-galactose-induced aging mice

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Antioxidant potential and physicochemical properties of protein hydrolysates from body parts of North Atlantic sea cucumber (Cucumaria frondosa)

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Marine bioactive peptides with anticancer potential, a narrative review

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The effects of jaspamide on human cardiomyocyte function and cardiac ion channel activity

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Identification of ACE inhibitory peptides from red alga Mazzaella japonica

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Structural Evidence for Antihypertensive Effect of an Antioxidant Peptide Purified from the Edible Marine Animal Styela clava

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Marine-Derived Bioactive Proteins and Peptides: A Review of Current Knowledge on Anticancer Potentials, Clinical Trials, and Future Prospects

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Cytotoxic Potential of the Novel Horseshoe Crab Peptide Polyphemusin III

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A novel angiotensin I-converting enzyme inhibitory peptide derived from the trypsin hydrolysates of salmon bone proteins

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OctoPartenopin: Identification and Preliminary Characterization of a Novel Antimicrobial Peptide from the Suckers of Octopus vulgaris

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Purification and identification of anti-inflammatory peptides from sturgeon (Acipenser schrenckii) cartilage

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Nile Tilapia Derived TP4 Shows Broad Cytotoxicity toward to Non-Small-Cell Lung Cancer Cells

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Evaluation of sea cucumber peptides-assisted memory activity and acetylation modification in hippocampus of test mice based on scopolamine-induced experimental animal model of memory disorder

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Characterization and identification of novel anti-inflammatory peptides from Baijiao sea bass (Lateolabrax maculatus)

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A Prototype Skin Substitute, Made of Recycled Marine Collagen, Improves the Skin Regeneration of Sheep

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Commercial Potential of the Cyanobacterium Arthrospira maxima: Physiological and Biochemical Traits and the Purification of Phycocyanin

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Antioxidant and Anti-Inflammatory Effects of NCW Peptide from Clam Worm ( Marphysa sanguinea )

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Valorisation of fish scales and bones: a sustainable source of bioactive proteins and collagen for nutraceuticals

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Marine nutraceuticals as a source of SIRT1 and NRF2 activators for diabetes and aging-related metabolic disorders

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Marine Bioactive Peptides in the Regulation of Inflammatory Responses: Current Trends and Future Directions

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Marine Antimicrobial Peptides: Emerging Strategies Against Multidrug-Resistant and Biofilm-Forming Bacteria

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Separation, characterization, AI screening, and bioactivities of marine bioactive peptides: A review

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Polysaccharides from echinoderms: unlocking health benefits and food applications – a review

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Anti‐Inflammatory Potential of Fish‐Derived Bioactive Peptides: Molecular Mechanisms, Delivery Strategies, and Clinical Perspectives

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From Ocean to Market: Technical Applications of Fish Protein Hydrolysates in Human Functional Food, Pet Wellness, Aquaculture and Agricultural Bio-Stimulant Product Sectors

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Enzymatic valorization of fishery by-products: harnessing cold-adapted marine proteases for sustainable production of bioactive peptides

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Recent advances in antidiabetic marine-derived bioactive peptides: production, therapeutic targets, structure–function relationship, and bioavailability

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Blue food proteins-derived immunomodulatory peptides: sources, preparation, identification techniques, mechanisms, and critical challenges of commercial application

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A novel angiotensin-converting enzyme (ACE) inhibitory peptide from Alaska pollock (Gadus chalcogrammus) Skin: Preparation, screening, in vitro activity evaluation, and network pharmacology analysis

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Walnut (Juglans regia L.) glutelin-derived peptides as novel candidates for cognitive enhancement: targeting oxidative stress and neuroinflammation

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Marine Bioactive Compounds from Functional Seafoods: Pharmacological Mechanisms and Health Applications

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Crustacean and Mollusc Shell Proteins: Origin, Structure, and Functionality

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Navigating the potential of algal peptides: health effects, market applications, and scientific challenges

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Antioxidant activity and anti-melanogenic of the exopolysaccharide EPS-HuA40 from Mesonia sp. HuA40

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Oral Collagen Oligopeptides as a Modulator of Skin Health: A Comprehensive Evaluation of Clinical and Molecular Effects

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Proteomics and bioinformatics guided discovery of microalgal multifunctional peptides for novel nutraceutical applications

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Improvement Effect and Regulation Mechanism of Oyster Peptide on Dexamethasone-Induced Osteoporotic Rats

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Novel peptides from the edible bivalve Ruditapes decussatus target apoptosis, autophagy, and FGF19-FGFR4 signaling in human cancer cell lines

Hussein, A. A. A., Salem, M. B., Elzallat, M., Ghoname, S. I., Habib, M. R., Hammam, O. A., El-Dabaa, E., & Okasha, H. (2025) · Scientific Reports · doi:10.1038/s41598-025-20094-7 · Cited by 3 · see citing works

Enhancement of antioxidant properties and gastrointestinal stability of instant soup powder through marine collagen peptide fortification

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Marine-derived Peptides As Anti-biofilm and Anti-virulence Agents: Mechanistic Insights and Applications Against Microbial Pathogens

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Collagen peptides from marine by-products: From waste to functional ingredients

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Cold-water versus warm-water fish collagen (Type I): Comparative functional properties and implications for food industry applications

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Antimicrobial Peptides in Fish: Mechanisms of Action and Applications in Aquaculture

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Mechanism of tilapia skin antioxidant pentapeptide on atherosclerosis: Inhibition of angiogenesis and oxidative stress

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Maximizing the utilization of seafood resources

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A Stable Delivery System for Meretrix meretrix Derived Immunomodulatory Peptide (QLNWD): Fabrication and Characterization of Glycosylated Protein Nanoparticle

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Oyster Peptides Prepared by Lactobacillus casei Fermentation Enhance Immune Activity in RAW264.7 Cells via Activation of the MAPK Pathway

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Selective release of antioxidant peptides and minerals from fermented SC-CO2-defatted Spirulina

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Integrating Computational and Experimental Approaches for the Discovery of Multifunctional Peptides from the Marine Gastropod Pisania pusio with Antimicrobial and Anticancer Properties

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Natural sources and bioactive mechanisms of anti-inflammatory peptides: from digestive metabolism to bioavailability enhancement strategies

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Fractionation, characterization, and gastrointestinal stability of anticancer and antioxidant peptides from sea cucumber (Holothuria scabra) hydrolysates

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Collagenase from Marine Sediment Bacillus subtilis dfs3 Using Fish Waste Substrate: Purification and Characterization

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Marine bioactive compounds in the management of zoonotic parasitic diseases: public health ramifications, mechanisms, and translational prospects

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Fabrication and characterization of electrospun polycaprolactone/ Urechis unicinctus derived-ECM composite scaffolds for small-diameter vascular grafts

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Peptides with antioxidant and antibacterial potential in anion‐exchange fractions of pepsin‐hydrolyzed IPB ‐ D1 chicken egg white

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Synergistic Effects of Chitosan Nanoparticles and Seaweed Extract in Accelerating Burn Wound Healing and Combating Microbial Infections

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Ultrafiltration Fractions of Hydrolysates of Cooked Shrimp ( Litopenaeus vannamei ) Byproducts Obtained by Different Enzymatic Treatments: Comparison of Amino Acid Composition and Antioxidant Capacity

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Comparison of Pretreatment Methods for Obtaining Collagen Hydrolysates from the Swim Bladder of Totoaba macdonaldi and Their Negative Impact on Cancer Cells

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Advances in marine bioactive compounds for cell-cultured fish: from cellular regulation to application strategies

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Fish protein hydrolysates from mackerel (Scomberomorus commerson) muscle and skin by-products fermented by Pediococcus pentosaceus IL13: Antioxidant, anti-inflammatory activities, and bioactive peptide identification

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Bioactive peptides in aquaculture: a peptidomics approach to food security

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Marine Bioactive Peptides for Colorectal Cancer Therapy: Mechanisms, Therapeutic Potential, and Translational Challenges

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From Bioactivity to Functionality: Bridging Marine Chemical Diversity and Performance in Food Systems

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Marine-Derived Proteins: Emerging Nutritional Strategies for Optimizing Athletic Performance

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Molecular Regulation of Virulence and Dental Biofilm Formation in Streptococcus mutans : Unravelling the Crosstalk Between the VicRK and LiaSR Two‐Component Systems

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From In Silico De Novo Generation to In Vitro Functional Validation: Discovery of Multifunctional Antithrombotic Peptides from Food-Derived Proteins via a Hybrid LSTM-GCN and Molecular Simulation Pipeline

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Natural antihypertensive agents: innovative extraction techniques: Bioactive profiling and mechanistic pathways for therapeutic development

Ramachandran, R., Alwi, R. S., Mazaya, M., Prem, P., Kamaraj, C., Maytasyaa, S., & Soleha, M. (2025) · South African Journal of Botany · doi:10.1016/j.sajb.2025.11.039

Fermentation-Driven Generation of α-Glucosidase Inhibitory Whey Peptides by Marine-Derived Probiotic Lacticaseibacillus casei DS31: Activity Enrichment and Peptidomics

Zhang, H., Tang, X., Yang, L., Yang, S., & Wu, P. (2026) · Fermentation · doi:10.3390/fermentation12020074

Marine-derived polysaccharides and peptides as next-generation immunomodulators: Molecular mechanisms, therapeutic potential, and translational challenges

Chandrasekaran, K., Desai, D., Singh, S. K., Manoharan, J., & Selvaraj, C. (2026) · Advances in protein chemistry and structural biology · doi:10.1016/bs.apcsb.2026.01.003

Deamidation of Fish Skin Collagen using Protein-GlutaminasePreprint

Yagonia, C. F. J., Leonard, A. R., Hall, B., & Cumming, M. H. (2026) · SSRN Electronic Journal · doi:10.2139/ssrn.6250997

Utilization of Pterygoplichthys pardalis as an alternative protein source in Nile tilapia feed: Effects on growth performance and health indicators

Darwis, Ridwanudin, A., Samsudin, R., & Suryaningrum, L. H. (2026) · The Egyptian Journal of Aquatic Research · doi:10.1016/j.ejar.2026.01.001

Deamidation of fish skin collagen using protein-glutaminase

Yagonia, C. F. J., Leonard, A. R., Hall, B., & Cumming, M. H. (2026) · Food Bioscience · doi:10.1016/j.fbio.2026.108663

Marine bacterial metabolites in anticancer drug discovery: Ecological insights, mechanisms of action, and clinical translation

Theivendren, P., Panneerselvam, S., Swaminathan, J., Murugesan, V., Pradeep, K., Bhat, M. J., Zarfishan, A., Chidambaram, K., & Kiruthiga, N. (2026) · Regional Studies in Marine Science · doi:10.1016/j.rsma.2026.104935

Mitochondrial rescue in Alzheimer’s disease: Exploring marine-derived compounds for brain metabolism regulation

Vijayalakshmi, P., Alex, A. M., Muthupandian, S., Desai, D., Jayaprakashvel, M., Singh, S. K., & Selvaraj, C. (2026) · International review of neurobiology · doi:10.1016/bs.irn.2026.02.003

Marine-Derived Anticancer Compounds and their Clinical Status

Kumar, D., Goyal, K., & Sharma, P. K. (2026) · Anti-Cancer Agents in Medicinal Chemistry · doi:10.2174/0118715206450961260106111347

Characterization and bioactivities of a novel copper–zinc superoxide dismutase from the marine snail Rapana venosa: antioxidant, antimicrobial, and anticancer effects

Saleh, M. A., Habib, M. R., AbdElGhany, S. R., Abouel-Nour, M. F., & Masoud, H. M. M. (2026) · Beni-Suef University Journal of Basic and Applied Sciences · doi:10.1186/s43088-026-00759-6

Valorization of the invasive blue crab in the mediterranean: life cycle assessment within a circular economy framework

Yemmen, C., Baizig, M., & Gargouri, M. (2026) · Euro-Mediterranean Journal for Environmental Integration · doi:10.1007/s41207-026-01105-z

Jellyfish bioactive compounds fueling marine biotechnology in blue economy and biomedicine

Spina, E. L., Barbagallo, I. A., Giallongo, C., Longhitano, L., Leotta, P., Conti, G., Giallongo, S., Lombardo, S. P., Felici, A., Bellia, F., et al. (2026) · Frontiers in Marine Science · doi:10.3389/fmars.2026.1760658

Screening and characterization of a novel cupin-like polypeptide from Oyster (Ostrea gigas) and its anti-inflammatory effect via TAK1 mediated NF-κB pathway

Li, C., Xiang, Y., Jiang, T., Zhang, J., Xia, X., & Liu, A. (2026) · Food Chemistry X · doi:10.1016/j.fochx.2026.103884

A Comprehensive Review on the Anticancer Activity of Plant Peptides and Their Mechanisms of Action

Hou, T., Wang, Y. F., Yao, Y., Hu, Y., Netala, V. R., & Li, H. (2026) · Foods · doi:10.3390/foods15091532

Isolation, Structures, and Mechanisms of Anti-Tumor Peptides from Marine Organisms: A Review

Xu, X., Peng, J., & Shi, H. (2026) · Protein and Peptide Letters · doi:10.2174/0109298665451278260413074905

Peptidomic characterization and evaluation of in vitro and in vivo anticoagulant activities of proteinase K hydrolysates from the deep-sea cold seep clam Archivesica marissinica

Ouyang, Y., Yang, Y., Chen, H., Wang, J., Wu, N., Geng, L., & Zhang, Q. (2026) · Food Bioscience · doi:10.1016/j.fbio.2026.109007

AI-driven discovery of an allosteric thrombin-targeting anticoagulant peptide from traditional Chinese medicine Dilong (Pheretima aspergillum)

Xie, X., Ding, J., Tang, H., Deng, J., Liu, J., Zhang, M., 余伯阳, & Liu, X. (2026) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2026.121855

Isolation and Characterization of St-CRPs: Cysteine-Rich Peptides from the Arctic Marine Ascidian Synoicum turgens

Hansen, I. K. Ø., Rainsford, P., Isaksson, J., Hansen, K. Ø., Stensvåg, K., Albert, A., Vasskog, T., & Haug, T. (2026) · Marine Drugs · doi:10.3390/md24050168

Marine-derived PUFAs and peptides for aging-related memory deficits: processing methods, pharmacokinetics, mechanistic insights, and clinical application

Yang, Z., Deng, W., Lu, Q., Zhou, Z., Song, C., & Naqvi, S. N.-U.-A. (2026) · Frontiers in Nutrition · doi:10.3389/fnut.2026.1844290

Antioxidant, Anti-Inflammatory and Anticancer Peptides from Extreme Marine Environments

Zakariya, M., Montuori, E., Kopp, G., Coppola, A., Giordano, D., Bruno, S., & Lauritano, C. (2026) · Antioxidants · doi:10.3390/antiox15050615

Immunomodulatory effect of rice bran peptides on RAW264.7 cells

Lin, W., Sui, X., Liu, X., & Zheng, X. (2026) · Food & Function · doi:10.1039/d6fo01738j

Characterization of bioactive compounds in mussel protein hydrolysates

Pertiwi, R. T. A., Pringgenies, D., Dewi, E., & Sabdaningsih, A. (2026) · IOP Conference Series Earth and Environmental Science · doi:10.1088/1755-1315/1618/1/012023

Editorial for Special Issue “Recombinant Proteins for Molecular Biology Research: Technologies and Applications”

Arakawa, T. (2026) · Current Issues in Molecular Biology · doi:10.3390/cimb48060604

Low molecular weight marine protein hydrolysates as fish meal substitutes enhance growth, nutrient digestibility, innate immunity and gut health in red seabream (Pagrus major)Preprint

Lee, K., Song, S., Levallois, T., & Lee, K. (2026) · SSRN Electronic Journal · doi:10.2139/ssrn.6926153

Preparation, identification, and active sites of antioxidant peptides from Hakka Huangjiu lees protein hydrolysates: from virtual analysis to experimental validation

Wang, W., Qiu, Z., Fang, X., Qian, M., Zeng, L., Zhang, M., & Xin, X. (2026) · Food Bioscience · doi:10.1016/j.fbio.2026.109307

Integrated structural and molecular characterization reveals multifunctional bioactivities of abalone-derived peptides

Jiang, X., Liu, H., Jiang, M., Wen, H., Zheng, J., Jiang, Q., Lan, C., Qin, Z., Wang, X., & Jiang, M. (2026) · International Journal of Food Properties · doi:10.1080/10942912.2026.2687907

In Vitro Gastrointestinal Digestion of Calanus finmarchicus Products: Amino Acid Composition, Degree of Hydrolysis, Antioxidant Capacity, and Antidiabetic Activity

Wang, Y., Eilertsen, K., Elvevoll, E. O., Li, C., & Jensen, I. (2026) · Marine Drugs · doi:10.3390/md24070240

Simulated Gastrointestinal Digestion of Tilapia (Oreochromisniloticus) Scale Hydrolysates Enhances ACE-Inhibitory Activity and Reveals Antioxidant Effects in STC-1 Cells

Sisa, A., Mosquera, M. E., Martín-Brieva, P., Moreno-Ortega, P., & Martínez‐Álvarez, Ó. (2026) · Foods · doi:10.3390/foods15142422

Marine-derived natural products as adaptogens: Enhancing fish resilience to climate and environmental stressors

Azemi, A. K., Zakaria, N. H., Segaran, T. C., Sung, Y. Y., Ghaffar, M. A., Lian, W. L., Nordin, M. L., & Muhammad, T. S. T. (2026) · Regional Studies in Marine Science · doi:10.1016/j.rsma.2026.105212

Investigation of Antidiabetic Properties and Mechanisms of Hake (Merluccius merluccius) By-Products Hydrolysates using Molecular Docking

Belkhodja, H., Argoub, K., REMIL, A., Belkhadem, F., Bouhadi, D., & Goutni, M. E. A. E. (2026) · Thalassas An International Journal of Marine Sciences · doi:10.1007/s41208-026-01192-3

Modulation of platelet activation and aggregation by intra-articular chondroprotectants as a factor enhancing the therapeutic potential of platelet-rich plasma

Burka, I. S., Сиротенко, В. С., Malanin, D. A., Demeshchenko, M. V., Zaslavskaya, K. Y., & Lepshokov, M. R. (2026) · Bulletin of the Russian Military Medical Academy · doi:10.17816/brmma707220

Targeted discovery of linear lipopeptides from the marine-derived fungus Myrothecium inundatum by a building blocks-based molecular networking strategy

Hu, B., Hu, J., Seo, E., Sun, Y., Wang, B., Ma, K., & Lin, W. (2026) · Phytochemistry Letters · doi:10.1016/j.phytol.2026.104233

Chemical Profiling and In Vitro Bioactivities of Extracts from the Red Alga Jania rubens Collected from the Lebanese Coast

Kassir, R., EL-Mched, F., Radwan, Z., Dassouki, Z., & Mawlawi, H. (2026) · Marine Drugs · doi:10.3390/md24090295

Blue proteins: Marine-derived alternatives for sustainable nutrition and climate-resilient food systems

Likson, A., Brindha, K., Desai, D., Ramanathan, S., Bhuvaneshwari, S., & Selvaraj, C. (2026) · Advances in protein chemistry and structural biology · doi:10.1016/bs.apcsb.2026.08.002

Circular Valorization of Yellowfin Tuna (Thunnus albacares) Bone By-Products into Bioactive Hydrolysates Using Endogenous Visceral Proteases Compared with Commercial Trypsin

Encalada, A. B., Sisa, A., Garcés, K., Donoso, C., Peñaherrera, E., Martínez‐Álvarez, Ó., Ruales, J., & Mosquera, M. E. (2026) · Molecules · doi:10.3390/molecules31172996

Whey: A source of bioactive peptides

Vieira, C. P., Vieira, Í. R. S., Júnior, A. A. M., Gutiérrez-Álzate, K., Nascimento, J. C. N., Almeida, A. C. D. O., de Souza, H. C. A., dos Santos, A. M. P., Álvares, T. S., & Junior, C. A. C. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-27648-4.00006-2

Mollusks

Τσούπρας, Α., Traga, T.-E., & Anastasiadou, C. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-27500-5.00018-6

Effects of Protease-Hydrolyzed and Cordyceps militaris-Fermented Sea Cucumber Viscera Hydrolysates on Cellular Function and Energy Metabolism in HCT116 Cells

Chen, B., Li, Y., Chen, X., Jia, X., Li, Y., Mi, R., & Zhou, Z. (2026) · Foods · doi:10.3390/foods15173065

Antitumor Effects of Collagen Peptide Nanoemulsion and Nanoliposome Prepared from Taiwan Tilapia Skin in a Mouse Model

Inbaraj, B. S., Hsu, K., & Chen, B. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27177835

Food-derived bioactive peptides for anxiety alleviation: mechanistic insights from gut–brain axis modulation, advanced evaluation, and AI-assisted discovery

Wang, P., Ma, C., Yang, Y., Zhang, G., Xu, X., Wang, J., Li, L., Xu, Y., & Zhang, N. (2026) · Food Bioscience · doi:10.1016/j.fbio.2026.109856

Toxicological Assessment of the Marine-Derived Cyclic Dipeptide Cyclo(Pro-Tyr) Using In Vitro, Zebrafish Embryo, and BALB/c Mouse Models

Balachandran, S., Arumugam, M. K., & Kandy, R. R. K. (2026) · Journal of Xenobiotics · doi:10.3390/jox16050170

Mollusk-Derived Peptides at the Food-Pharma Interface: Bioactivities, Preclinical Evidence, and Development Prospects

Imran, M., Li, Y., Asif, M., Azam, M., Aleem, K., Jiang, Z., Adil, M., & Yi, Y. (2026) · Molecules · doi:10.3390/molecules31183186

Marine‐Derived Proteins: Individual Variability in Health Effects Across Protein Structure, Host Genetics, and Gut Microbiota

Song, J., Huang, J., Lan, Y., Miao, R., Tang, Z., Wu, J., Yu, M., Bliki, K., Skirtach, A. G., Zhu, S., et al. (2026) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.70649

Marine Collagen-Based Wound Dressings: Design Strategies and Therapeutic Potential

Chen, B., Bian, C., Wang, C., Liang, X., Li, N., Yana, Q., AHSAN, J., Elango, J., & Wu, W. (2026) · MarineMedicine · doi:10.64187/mm.2026.v2.i2.006

Pacific oyster-derived peptides: extraction optimization, structural characterization, and functional evaluation

Liu, H., Jiang, X., Jiang, M., Wen, H., Zheng, J., Lan, C., Jiang, M., Qin, Z., & Chen, L. (2026) · 3 Biotech · doi:10.1007/s13205-026-05049-7

Effects of moisture content on the co-oxidation behavior of sturgeon myofibrillar protein and sturgeon oil

Fang, Y., Yin, Z., Yu, J., Huang, G., & Li, J. (2026) · Food Chemistry X · doi:10.1016/j.fochx.2026.104481

Bioactive peptides in cancer and inflammation: Mechanisms, model systems and clinical translation

Doha, N., Gill, R., Crovella, S., Abou-Saleh, H., & Da'as, S. I. (2026) · Clinical and Translational Discovery · doi:10.1002/ctd2.70209

Regulatory Effects of Marine-Derived Peptides on Digestive and Metabolic Enzymes via Ionic Chelation: A Review

Xu, Z., Sun, J., Qin, Z., Zhao, S., Zhou, S., Wang, F., Guan, S., & Li, T. (2026) · Food Reviews International · doi:10.1080/87559129.2026.2734290

Marine Fish-Derived ACE-Inhibitory Peptides: Preparation via Enzymatic Hydrolysis and Their In Vitro Activity

Zhao, Y., Su, Y., Cai, S., Chen, B., Qiao, K., & Liu, Z. (2026) · Marine Drugs · doi:10.3390/md24100333

Treasures from the Ocean: Deciphering the Therapeutic Utility of Marine-Derived ACE-Inhibitory Peptides in Cardiovascular Drug Discovery

Sathsarani, N. A. S. N., Yim, M., Wijerathne, H. D. T. U., Herath, K. H. I. N. M., Lee, J. M., Sanjeewa, K. K. A., & Kim, H.-S. (2026) · Pharmaceuticals · doi:10.3390/ph19101533

Marine-Derived Bioactive Peptides for Biomedical Sectors: A Review

Ruiz‐Ruiz, F., Mancera-Andrade, E. I., & Iqbal, H. M. N. (2016) · Protein and Peptide Letters · doi:10.2174/0929866523666160802155347 · Cited by 48 · see citing works

Proteins and Peptides

Hofmann, A., Atamaniuk, I., & Kuchta, K. (2025) · Royal Society of Chemistry eBooks · doi:10.1039/9781837678198-00186

The Production, Properties, and Potential Food Applications of Proteins and Peptides from Marine Sources and their Structure-Function Relationship

Mirzakhani, E., Lee, C. C., Ashaolu, T. J., Abass, K. S., Ansari, F., & Pourjafar, H. (2026) · Current Protein and Peptide Science · doi:10.2174/0113892037441673260131191900 · Cited by 1 · see citing works

Bioactive Peptides from Marine Organisms

Wang, P., Zhang, Y., Hu, J., & Tan, B. K. (2024) · Protein and Peptide Letters · doi:10.2174/0109298665329840240816062134 · Cited by 18 · see citing works

Marine-derived products as pharmaceutical treasure troves: a focus on recent research techniques and potential bioactive activities of marine peptides

Cheng, X., Tang, Z., Li, Z., Hu, S., Qin, K., Zhao, Y., Hao, B., & Hu, Q. (2026) · Chinese Journal of Natural Medicines · doi:10.1016/s1875-5364(26)61178-8 · Cited by 2 · see citing works