Kaiso Contributes to DNA Methylation-Dependent Silencing of Tumor Suppressor Genes in Colon Cancer Cell Lines

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Loss of IGF2 Imprinting: A Potential Marker of Colorectal Cancer Risk

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Tumor Suppressor HIC1 Directly Regulates SIRT1 to Modulate p53-Dependent DNA-Damage Responses

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The p120 catenin partner Kaiso is a DNA methylation-dependent transcriptional repressor

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DNA methylation and its basic function

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Transcription factors as readers and effectors of DNA methylation

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Mechanisms of Motility in Metastasizing Cells

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Colorectal Cancer Epigenetics: Complex Simplicity

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p120-catenin is essential for maintenance of barrier function and intestinal homeostasis in mice

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Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso

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DNA Methylation Readers and Cancer: Mechanistic and Therapeutic Applications

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The Roles of the Methyl-CpG Binding Proteins in Cancer

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Sequence-specific recognition of methylated DNA by human zinc-finger proteins

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Epigenetic modifications in colorectal cancer: Molecular insights and therapeutic challenges

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A Structural Perspective on Readout of Epigenetic Histone and DNA Methylation MarksPreprint

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Nanopore-Based Assay for Detection of Methylation in Double-Stranded DNA Fragments

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ZBTB33 binds unmethylated regions of the genome associated with actively expressed genes

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Gestational exposure to the AhR agonist 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin induces BRCA‐1 promoter hypermethylation and reduces BRCA‐1 expression in mammary tissue of rat offspring: Preventive effects of resveratrol

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The Molecular Evolution of the p120-Catenin Subfamily and Its Functional Associations

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Distinct contributions of DNA methylation and histone acetylation to the genomic occupancy of transcription factorsPreprint

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Nuclear Kaiso Indicates Aggressive Prostate Cancers and Promotes Migration and Invasiveness of Prostate Cancer Cells

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Zinc Finger Readers of Methylated DNA

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Mammary Tumor-Associated RNAs Impact Tumor Cell Proliferation, Invasion, and Migration

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Kaiso Represses the Cell Cycle Gene cyclin D1 via Sequence-Specific and Methyl-CpG-Dependent Mechanisms

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Nuclear Kaiso Expression Is Associated with High Grade and Triple-Negative Invasive Breast Cancer

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Cell-specific Kaiso (ZBTB33) Regulation of Cell Cycle through Cyclin D1 and Cyclin E1

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Modifiers and Readers of DNA Modifications and Their Impact on Genome Structure, Expression, and Stability in Disease

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The non-methylated DNA-binding function of Kaiso is not required in earlyXenopus laevisdevelopment

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Dancing from bottoms up – Roles of the POZ-ZF transcription factor Kaiso in Cancer

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Wnt controls the transcriptional activity of Kaiso through CK1ε-dependent phosphorylation of p120-catenin

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KAISO, a critical regulator of p53-mediated transcription of CDKN1A and apoptotic genes

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Kaiso, a transcriptional repressor, promotes cell migration and invasion of prostate cancer cells through regulation of miR-31 expression

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Small-molecular modulators of cancer-associated epigenetic mechanisms

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Large intestine embryogenesis: Molecular pathways and related disorders (Review)

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Nuclear localization of Kaiso promotes the poorly differentiated phenotype and EMT in infiltrating ductal carcinomas

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Cytoplasmic Kaiso is associated with poor prognosis in non-small cell lung cancer

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Insights into the role of DNA methylation in disease through the use of mouse models

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Kaiso depletion attenuates transforming growth factor-β signaling and metastatic activity of triple-negative breast cancer cells

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Inhibition of the H3K27 demethylase UTX enhances the epigenetic silencing of HIV proviruses and induces HIV-1 DNA hypermethylation but fails to permanently block HIV reactivation

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Kaiso depletion attenuates the growth and survival of triple negative breast cancer cells

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Kaiso overexpression promotes intestinal inflammation and potentiates intestinal tumorigenesis in ApcMin/+ mice

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The Roles of Zinc Finger Proteins in Colorectal Cancer

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Methylation-dependent regulation of hypoxia inducible factor-1 alpha gene expression by the transcription factor Kaiso

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The Transcriptional Repressor Kaiso Localizes at the Mitotic Spindle and Is a Constituent of the Pericentriolar Material

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Kaiso Directs the Transcriptional Corepressor MTG16 to the Kaiso Binding Site in Target Promoters

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DNA methylation and the core pluripotency network

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DNA methylation profiling using HpaII tiny fragment enrichment by ligation-mediated PCR (HELP)

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The POZ-ZF Transcription Factor Kaiso (ZBTB33) Induces Inflammation and Progenitor Cell Differentiation in the Murine Intestine

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Kaiso uses all three zinc fingers and adjacent sequence motifs for high affinity binding to sequence‐specific and methyl‐CpG DNA targets

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Kaiso is highly expressed in TNBC tissues of women of African ancestry compared to Caucasian women

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The C-Terminal Zinc Fingers of ZBTB38 are Novel Selective Readers of DNA Methylation

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Aberrant DNA Methylation Mediates the Transgenerational Risk of Metabolic and Chronic Disease Due to Maternal Obesity and Overnutrition

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Knock-down of Kaiso induces proliferation and blocks granulocytic differentiation in blast crisis of chronic myeloid leukemia

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Cys2His2 Zinc Finger Methyl-CpG Binding Proteins: Getting a Handle on Methylated DNA

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Mammalian methyl‐binding proteins: What might they do?

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African Americans with pancreatic ductal adenocarcinoma exhibit gender differences in Kaiso expression

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Advanced Computational Biology Methods Identify Molecular Switches for Malignancy in an EGF Mouse Model of Liver Cancer

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Novel DNA Binding Domain-Based Assays For Detection of Methylated And Nonmethylated DNA

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Kaiso-induced intestinal inflammation is preceded by diminished E-cadherin expression and intestinal integrity

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Diabetic kidney disease: A systematic review on the role of epigenetics as diagnostic and prognostic marker

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Kaiso mainly locates in the nucleus in vivo and binds to methylated, but not hydroxymethylated DNA.

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Solid-state nanopore fabrication in LiCl by controlled dielectric breakdown

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KAISO inhibition: an atomic insight

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Kaiso protects human umbilical vein endothelial cells against apoptosis by differentially regulating the expression of B-cell CLL/lymphoma 2 family members

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Leukocyte DNA methylation and colorectal cancer among male smokers

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Kaiso is required for MTG16-dependent effects on colitis-associated carcinoma

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Genome-wide DNA methylation sequencing identifies epigenetic perturbations in the upper airways under long-term exposure to moderate levels of ambient air pollution

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Gene insulation. Part II: natural strategies in vertebrates

Amouyal, M. (2010) · Biochemistry and Cell Biology · doi:10.1139/o10-111 · Cited by 10

Kaiso represses the expression of glucocorticoid receptor via a methylation-dependent mechanism and attenuates the anti-apoptotic activity of glucocorticoids in breast cancer cells

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Expression of P120 catenin, Kaiso, and metastasis tumor antigen-2 in thymomas

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Distribution of Kaiso protein in mouse tissues

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The POZ-ZF transcription factor Znf131 is implicated as a regulator of Kaiso-mediated biological processes

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Cancer as an Embryological Phenomenon and Its Developmental Pathways: A Hypothesis regarding the Contribution of the Noncanonical Wnt Pathway

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Epigenetic Targets in Human Neoplasms

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A 5′-Flanking C/G Pair at the Core Region Enhances the Recognition and Binding of Kaiso to Methylated DNA

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Temporal and differential regulation of KAISO-controlled transcription by phosphorylated and acetylated p53 highlights a crucial regulatory role of apoptosis

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Spinal cord dorsal horn sensory gate in preclinical models of chemotherapy-induced painful neuropathy and contact dermatitis chronic itch becomes less leaky with Kcc2 gene expression-enhancing treatments

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Epigenetic Regulation of Dlg1 , via Kaiso , Alters Mitotic Spindle Polarity and Promotes Intestinal Tumorigenesis

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ZBTB33 (Kaiso) methylated binding sites are associated with primed heterochromatinPreprint

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DNA Methylation Identifies Loci Distinguishing Hereditary Nonpolyposis Colorectal Cancer Without Germ-Line MLH1/MSH2 Mutation from Sporadic Colorectal Cancer

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Long March Toward Safe and Effective Analgesia by Enhancing Gene Expression of Kcc2: First Steps Taken

Liedtke, W. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.865600 · Cited by 6

Bifunctional role of the zinc finger domains of the methyl-DNA-binding protein Kaiso

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Kaiso Protein Expression Correlates with Overall Survival in TNBC Patients

Bocian, A., Kędzierawski, P., Kopczyński, J., Wabik, O., Wawruszak, A., Kiełbus, M., Miziak, P. A., & Stepulak, A. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12010370 · Cited by 4

Imprinted DNA methylation of the H19 ICR is established and maintained in vivo in the absence of Kaiso

Matsuzaki, H., Kimura, M., Morihashi, M., & Tanimoto, K. (2024) · Epigenetics & Chromatin · doi:10.1186/s13072-024-00544-8 · Cited by 4

From aging to cancer: a DNA methylation journey

Martínez, N. P., & Agrelo, R. (2012) · Ageing Research · doi:10.4081/ar.2012.e4 · Cited by 3

Kaiso overexpression promotes an interferon immune response in murine intestines

Lessey, L. R., Adan, H., Robinson, S. C., Chaudhary, R., Sivakumar, S., Fairbairn, S. A., Mohammadi, D., Kim, K., Alleyne, D., Houlahan, K. E., et al. (2026) · BMC Genomics · doi:10.1186/s12864-026-13047-5 · Cited by 2

Kaiso mediates transcription and RNA splicing in colorectal carcinoma: role of BRCA1 in the Kaiso enhanceosome

Luo, W., Tripathi, M. K., Liu, Q., Chen, L., Cowan, R. W., Daniel, J. M., Yan, C. W., Richmond, A. J., & Reynolds, A. B. (2025) · Open Biology · doi:10.1098/rsob.240329 · Cited by 2

Kaiso phosphorylation at threonine 606 leads to its accumulation in the cytoplasm, reducing its transcriptional repression of the tumour suppressor CDH1

Tian, W., Yuan, H., Qin, S., Liu, W., Zhang, B., Gu, L., Zhou, J., & Deng, D. (2022) · Molecular Oncology · doi:10.1002/1878-0261.13292 · Cited by 2

DNA Methylation in Mammalian and Non-Mammalian Organisms

Moffat, M., James, P., Pennings, S., & Richard, R. (2012) · InTech eBooks · doi:10.5772/38181 · Cited by 2

Sensitive Detection of Transcription Factor Kaiso via Self‐Assembly of DNA on an Electrode Surface

Li, X., Yang, N., Zhang, Y., Li, H., Yin, T., Sun, L., & Li, G. (2014) · Electroanalysis · doi:10.1002/elan.201400380 · Cited by 2

Behavioral phenotyping of Kaiso-deficient mice

Korostina, V. S., & Kulikov, A. V. (2015) · Vavilov Journal of Genetics and Breeding · doi:10.18699/vj15.051 · Cited by 2

Behavioral phenotyping of mice with the Kaiso knockout gene

Korostina, V. S., & Kulikov, A. V. (2016) · Russian Journal of Genetics Applied Research · doi:10.1134/s2079059716040110 · Cited by 2

Epigenetics in infectious disease

Kanyal, A., Nahata, S., & Karmodiya, K. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-814259-2.00008-x · Cited by 2

Association of Kaiso and partner proteins in oral squamous cell carcinoma

Salam, H., Ahmed, S., Bari, M. F., Bukhari, U., Haider, G., Najeeb, S., & Mughal, N. (2022) · Journal of Taibah University Medical Sciences · doi:10.1016/j.jtumed.2022.12.013 · Cited by 2

Role of the Kaiso gene in the development of inflammation in Mucin-2 defcient mice

Litvinova, E. A., Achasova, K. M., Borisova, M. A., Zhenilo, S. V., Prokhortchouk, E., & Kozhevnikova, E. N. (2019) · Vavilov Journal of Genetics and Breeding · doi:10.18699/vj18.453 · Cited by 2

MADS specificity : Unravelling the dual function of the MADS domain protein FRUITFULL

van Mourik, H. (2017) · doi:10.18174/421563 · Cited by 2

Kaiso and Prognosis of Cancer in the Current Epigenetic Paradigm

Cofré, J. (2012) · InTech eBooks · doi:10.5772/33958 · Cited by 1

A proposed novel genetic and epigenetic effects of Betulinic acid against breast cancer cells: in silico and in vitro study.

Fadel, H. H., El-Wakeel, E., Donia, H. M., El-Rahman, M. A., EL-Esseily, H. A., & El-Sewedy, T. (2023) · Egyptian Journal of Chemistry · doi:10.21608/ejchem.2023.178370.7259 · Cited by 1

Epigenetic processes–driven disorders and therapeutics

Mohan, V., Thumoju, S., & Mohiuddin, M. K. (2023) · Elsevier eBooks · doi:10.1016/b978-0-443-21863-7.00001-9 · Cited by 1

Institutional Profile: The Einstein Center for Epigenomics: Studying the Role of Epigenomic Dysregulation in Human Disease

McLellan, A. S., Dubin, R. A., Jing, Q., Maqbool, S. B., Olea, R., Westby, G., Broin, P. Ó., Fazzari, M. J., Zheng, D., Suzuki, M., et al. (2009) · Epigenomics · doi:10.2217/epi.09.9 · Cited by 1

The Chromatin Interaction System

Kreuz, S., David, S.-S., Cortés-Medina, L. V., & Fischle, W. (2022) · Wiley eBooks · doi:10.1002/9783527830503.ch11 · Cited by 1

[The Roles of P120-catenin and the Ttranscriptional Factor Kaiso for the Tumor.].

Sun, C., Li, Y., & Zhang, P. (2009) · PubMed · doi:10.3779/j.issn.1009-3419.2009.08.19

The p120 catenin partner Kaiso is a DNA methylation-dependent transcriptional repressor

Prokhortchouk, A., Hendrich, B., Jørgensen, H., Ruzov, A., Wilm, M., Georgiev, G., Bird, A., & Prokhortchouk, E. (2001) · Genes & Development · doi:10.1101/gad.198501 · Cited by 533

Discovery of Epigenetically Silenced Genes by Methylated DNA Immunoprecipitation in Colon Cancer Cells

Jacinto, F. V., Ballestar, E., Ropero, S., & Esteller, M. (2007) · Cancer Research · doi:10.1158/0008-5472.can-07-2687 · Cited by 93

Genetic unmasking of epigenetically silenced tumor suppressor genes in colon cancer cells deficient in DNA methyltransferases

Paz, M. F. (2003) · Human Molecular Genetics · doi:10.1093/hmg/ddg226 · Cited by 127

Klotho, an anti-senescence related gene, is frequently inactivated through promoter hypermethylation in colorectal cancer

Pan, J., Zhong, J., Gan, L., Chen, S. J., Jin, H., Wang, X., & Wang, L. J. (2011) · Tumor Biology · doi:10.1007/s13277-011-0174-5 · Cited by 86

Kaiso Represses the Cell Cycle Gene cyclin D1 via Sequence-Specific and Methyl-CpG-Dependent Mechanisms

Donaldson, N. S., Pierre, C. C., Anstey, M. I., Robinson, S. C., Weerawardane, S., & Daniel, J. M. (2012) · PLoS ONE · doi:10.1371/journal.pone.0050398 · Cited by 58