The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Coevolution of Prostate Cancer and Bone Stroma in Three-Dimensional Coculture: Implications for Cancer Growth and Metastasis
Open accessAbstract
Human bone stromal cells, after three-dimensional coculture with human prostate cancer (PCa) cells in vitro, underwent permanent cytogenetic and gene expression changes with reactive oxygen species serving as mediators. The evolved stromal cells are highly inductive of human PCa growth in mice, and expressed increased levels of extracellular matrix (versican and tenascin) and chemokine (BDFN, CCL5, CXCL5, and CXCL16) genes. These genes were validated in clinical tissue and/or serum specimens and could be the predictors for invasive and bone metastatic PCa. These results, combined with our previous observations, support the concept of permanent genetic and behavioral changes of PCa epithelial cells after being either cocultured with prostate or bone stromal cells as three-dimensional prostate organoids or grown as tumor xenografts in mice. These observations collectively suggest coevolution of cancer and stromal cells occurred under three-dimensional growth condition, which ultimately accelerates cancer growth and metastasis. [Cancer Res 2008;68(23):9996–10003]
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TGF-ß Signaling in Fibroblasts Modulates the Oncogenic Potential of Adjacent Epithelia
Bhowmick, N. A., Chytil, A., Plieth, D., Gorska, A. E., Dumont, N., Shappell, S., Washington, M. K., Neilson, E. G., & Moses, H. L. (2004) · Science · doi:10.1126/science.1090922 · Cited by 1,401
The use of 3-d cultures for high-throughput screening: the multicellular spheroid model.
Kunz-Schughart, L. A., Freyer, J. P., Hofstaedter, F., & Ebner, R. (2004) · SLAS DISCOVERY · doi:10.1177/1087057104265040 · Cited by 797
Selective Evolution of Stromal Mesenchyme with p53 Loss in Response to Epithelial Tumorigenesis
Hill, R., Song, Y., Cardiff, R. D., & Van Dyke, T. (2005) · Cell · doi:10.1016/j.cell.2005.09.030 · Cited by 324
Cited by
Oxidative stress, inflammation, and cancer: How are they linked?
Reuter, S., Gupta, S. C., Chaturvedi, M. M., & Aggarwal, B. B. (2010) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2010.09.006 · Cited by 5,441
Mesenchymal stem cells: key players in cancer progression
Ridge, S. M., Sullivan, F. J., & Glynn, S. A. (2017) · Molecular Cancer · doi:10.1186/s12943-017-0597-8 · Cited by 526
Activation of fibroblasts in cancer stroma
Räsänen, K., & Vaheri, A. (2010) · Experimental Cell Research · doi:10.1016/j.yexcr.2010.04.032 · Cited by 499
Design of spherically structured 3D in vitro tumor models -Advances and prospects
Ferreira, L. P., Gaspar, V. M., & Mano, J. F. (2018) · Acta Biomaterialia · doi:10.1016/j.actbio.2018.05.034 · Cited by 249
Darash-Yahana, M., Gillespie, J. W., Hewitt, S. M., Chen, Y.-Y. K., Maeda, S., Stein, I., Singh, S. P., Bedolla, R. B., Peled, A., Troyer, D. A., et al. (2009) · PLoS ONE · doi:10.1371/journal.pone.0006695 · Cited by 143
Metadata
- Authors
- Sung, S.-Y., Hsieh, C.-L., Law, A., Zhau, H. E., Pathak, S., Multani, A. S., Lim, S., Coleman, I. M., Wu, L.-C., Figg, W. D., Dahut, W. L., Nelson, P., Lee, J. K., Amin, M. B., Lyles, R., Johnstone, P. A. J., Marshall, F. F., & Chung, L. W. K.
- Venue
- Cancer Research
- Published
- 2008-12-01
- Volume
- 68
- Issue
- 23
- Pages
- 9996-10003
- ISSN
- 0008-5472 (ISSN-L)
- 1538-7445
- OpenAlex
- W2166159531
- Cited by
- 160
- References
- 3
- FWCI
- 11.69
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Sung, S.-Y., Hsieh, C.-L., Law, A., Zhau, H. E., Pathak, S., Multani, A. S., Lim, S., Coleman, I. M., Wu, L.-C., Figg, W. D., Dahut, W. L., Nelson, P., Lee, J. K., Amin, M. B., Lyles, R., Johnstone, P. A. J., Marshall, F. F., & Chung, L. W. K. (2008). Coevolution of Prostate Cancer and Bone Stroma in Three-Dimensional Coculture: Implications for Cancer Growth and Metastasis. Cancer Research. https://doi.org/10.1158/0008-5472.can-08-2492
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
