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Cited by 434

The DOI matches its Crossref record; 56 of the 56 references it cites were found in a registry or an index.

Clinical Importance of Pain and Stress in Preterm Neonates

Anand, K.J.S.·1998·Neonatology

Abstract

Clinical and laboratory investigations of neonatal pain suggest that preterm neonates have an increased sensitivity to pain and that acute painful stimuli lead to the development of prolonged periods of hyperalgesia. Non-noxious stimuli during these periods of hyperalgesia may expose preterm neonates to established or chronic pain. Acute physiologic changes caused by painful or stressful stimuli can be implicated as important factors in the causation or subsequent extension of early intraventricular hemorrhage (IVH) or the ischemic changes leading to periventricular leukomalacia (PVL). Therapeutic interventions that provide comfort/analgesia in preterm neonates were correlated with a decreased incidence of severe IVH. Long-term follow-up studies of preterm neonates may substantiate the preliminary data associating repetitive painful experiences with some of the neurobehavioral and developmental sequelae resulting from neonatal intensive care.

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Metadata

Authors
Anand, K. J. S.
Venue
Neonatology
Publisher
S. Karger AG
Published
1997-12-19
Volume
73
Issue
1
Pages
1-9
ISSN
  • 1661-7800 (ISSN-L)
  • 1661-7819
OpenAlex
W2069645475
Cited by
434
References
56
FWCI
12.19
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Clinical Importance of Pain and Stress in Preterm Neonates. https://app.cochat.ai/papers/10.1159/000013953
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Anand, K. J. S. (1998). Clinical Importance of Pain and Stress in Preterm Neonates. Neonatology. https://doi.org/10.1159/000013953

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.