The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Geographic and Ethnic Variation in Parkinson Disease: A Population-Based Study of US Medicare Beneficiaries
Open accessAbstract
Background: Parkinson disease is a common neurodegenerative disease. The racial, sex, age, and geographic distributions of Parkinson disease in the US are unknown. Methods: We performed a serial cross-sectional study of US Medicare beneficiaries aged 65 and older from the years 1995, and 2000–2005. Using over 450,000 Parkinson disease cases per year, we calculated Parkinson disease prevalence and annual incidence by race, age, sex, and county. Spatial analysis investigated the geographic distribution of Parkinson disease. Results: Age-standardized Parkinson disease prevalence (per 100,000) was 2,168.18 (±95.64) in White men, but 1,036.41 (±86.01) in Blacks, and 1,138.56 (±46.47) in Asians. The incidence ratio in Blacks as compared to Whites (0.74; 95% CI = 0.732–0.748) was higher than the prevalence ratio (0.58; 95% CI = 0.575–0.581), whereas the incidence ratio for Asians (0.69; 95% CI = 0.657–0.723) was similar to the prevalence ratio (0.62; 95% CI = 0.617–0.631). Bayesian mapping of Parkinson disease revealed a concentration in the Midwest and Northeast regions. Mean county incidence by quartile ranged from 279 to 3,111, and prevalence from 1,175 to 13,800 (per 100,000). Prevalence and incidence in urban counties were greater than in rural ones (p < 0.01). Cluster analysis supported a nonrandom distribution of both incident and prevalent Parkinson disease cases (p < 0.001). Conclusions: Parkinson disease is substantially more common in Whites, and is nonrandomly distributed in the Midwest and Northeastern US.
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de Rijk, M. C., Tzourio, C., Breteler, M. M., Dartigues, J. F., Amaducci, L., Lopez-Pousa, S., Manubens-Bertran, J. M., Alperovitch, A., & Rocca, W. A. (1997) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.62.1.10 · Cited by 833
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Rietdijk, C. D., Perez-Pardo, P., Garssen, J., van Wezel, R. J. A., & Kraneveld, A. D. (2017) · Frontiers in Neurology · doi:10.3389/fneur.2017.00037 · Cited by 395
Incidence of Parkinson disease in North America
Willis, A. W., Roberts, E., Beck, J. C., Fiske, B., Ross, W., Savica, R., Van Den Eeden, S. K., Tanner, C. M., Marras, C., on behalf of the Parkinson’s Foundation P4 Group, et al. (2022) · npj Parkinson's Disease · doi:10.1038/s41531-022-00410-y · Cited by 341
Self-citationNøhr, C., Sørensen, E. M., Gudes, O., Geraghty, E. M., Shaw, N. T., Bivona-Tellez, C., Lyseen, A. K., & the IMIA Health GIS Working Group (2014) · Yearbook of Medical Informatics · doi:10.15265/iy-2014-0008 · Cited by 120
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New hope for Parkinson’s disease treatment: Targeting gut microbiota
Fan, H., Sheng, S., & Zhang, F. (2022) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.13916 · Cited by 66
Achey, M. A., Beck, C. A., Beran, D. B., Boyd, C. M., Schmidt, P. N., Willis, A. W., Riggare, S. S., Simone, R. B., Biglan, K. M., & Dorsey, E. R. (2014) · Trials · doi:10.1186/1745-6215-15-465 · Cited by 27
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Metadata
- Authors
- Wright Willis, A., Evanoff, B. A., Lian, M., Criswell, S. R., & Racette, B. A.
- Venue
- Neuroepidemiology
- Publisher
- S. Karger AG
- Published
- 2010
- Volume
- 34
- Issue
- 3
- Pages
- 143-151
- ISSN
- 0251-5350 (ISSN-L)
- 1423-0208
- OpenAlex
- W2046690778
- Cited by
- 436
- References
- 1
- FWCI
- 9.38
- Type
- journal article
- Language
- en
- Open access
- green
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