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Cited by 571

The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.

The Incidence of Parkinson's Disease: A Systematic Review and Meta-Analysis

Hirsch, Lauren, Jette, Nathalie, Frolkis, Alexandra, Steeves, Thomas, Pringsheim, Tamara·2016·Neuroepidemiology

Abstract

Background: Parkinson's disease (PD) is a common neurodegenerative disorder. Epidemiological studies on the incidence of PD are important to better understand the risk factors for PD and determine the condition's natural history. Objective: This systematic review and meta-analysis examine the incidence of PD and its variation by age and gender. Methods: We searched MEDLINE and EMBASE for epidemiologic studies of PD from 2001 to 2014, as a previously published systematic review included studies published until 2001. Data were analyzed separately for age group and gender, and meta-regression was used to determine whether a significant difference was present between groups. Results: Twenty-seven studies were included in the analysis. Meta-analysis of international studies showed rising incidence with age in both men and women. Significant heterogeneity was observed in the 80+ group, which may be explained by methodological differences between studies. While males had a higher incidence of PD in all age groups, this difference was only statistically significant for those in the age range 60-69 and 70-79 (p < 0.05). Conclusion: PD incidence generally increases with age, although it may stabilize in those who are 80+.

Overview

Integrity signals

Registry

Crossref · 10.1159/000445751

Cites

39 of 39 references verified0 citation errors · 0 not checkable

Statistics

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Verification

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Citations

Cites

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Metadata

Authors
Hirsch, L., Jette, N., Frolkis, A., Steeves, T., & Pringsheim, T.
Venue
Neuroepidemiology
Publisher
S. Karger AG
Published
2016
Volume
46
Issue
4
Pages
292-300
ISSN
  • 0251-5350
  • 1423-0208
Cited by
571
References
39
Language
en
Licence

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This page
CoChat. (2026). Citation check: The Incidence of Parkinson's Disease: A Systematic Review and Meta-Analysis. https://app.cochat.ai/papers/10.1159/000445751
The paper
Hirsch, L., Jette, N., Frolkis, A., Steeves, T., & Pringsheim, T. (2016). The Incidence of Parkinson's Disease: A Systematic Review and Meta-Analysis. Neuroepidemiology. https://doi.org/10.1159/000445751

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.