Virtual house calls for Parkinson disease (Connect.Parkinson): study protocol for a randomized, controlled trial
Open accessAbstract
BACKGROUND: Interest in improving care for the growing number of individuals with chronic conditions is rising. However, access to care is limited by distance, disability, and distribution of doctors. Small-scale studies in Parkinson disease, a prototypical chronic condition, have suggested that delivering care using video house calls is feasible, offers similar clinical outcomes to in-person care, and reduces travel burden. METHODS/DESIGN: We are conducting a randomized comparative effectiveness study (Connect.Parkinson) comparing usual care in the community to usual care augmented by virtual house calls with a Parkinson disease specialist. Recruitment is completed centrally using online advertisements and emails and by contacting physicians, support groups, and allied health professionals. Efforts target areas with a high proportion of individuals not receiving care from neurologists. Approximately 200 individuals with Parkinson disease and their care partners will be enrolled at 20 centers throughout the United States and followed for one year. Participants receive educational materials, then are randomized in a 1:1 ratio to continue their usual care (control arm) or usual care and specialty care delivered virtually (intervention arm). Care partners are surveyed about their time and travel burden and their perceived caregiver burden. Participants are evaluated via electronic survey forms and videoconferencing with a blinded independent rater at baseline and at 12 months. All study activities are completed remotely.The primary outcomes are: (1) feasibility, as measured by the proportion of visits completed, and (2) quality of life, as measured by the 39-item Parkinson's Disease Questionnaire. Secondary outcomes include measures of clinical benefit, quality of care, time and travel burden, and caregiver burden. DISCUSSION: Connect.Parkinson will evaluate the feasibility and effectiveness of using technology to deliver care into the homes of individuals with Parkinson disease. The trial may serve as a model for increasing access and delivering patient-centered care at home for individuals with chronic conditions. TRIAL REGISTRATION: This trial was registered on clinicaltrials.gov on January 8, 2014 [NCT02038959].
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Large randomized-controlled trials of virtual house calls for PD are underway.
“large randomized-controlled trials (RCT) are underway (Achey et al., 2014”
From Remote delivery of psychological interventions for Parkinson's disease. (2018) · cites this paper as Achey et al., 2014
The Methods (Sample size; page unavailable) specify a randomized trial of 200 Parkinson disease patients, and Trial status says it was recruiting participants. This supports a substantial virtual-house-call trial underway, but the paper documents one such trial, not the plural 'trials' claimed. (LLM, conf=0.86)
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Comparison of office‐based versus home web‐based clinical assessments for Parkinson's disease
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The Multidimensional Caregiver Strain Index (MCSI): Its measurement and structure.
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Clinical Outcomes in a Prison Telepsychiatry Clinic
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A Telemedicine Model for Emergency Care in a Short-Term Correctional Facility
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A randomized trial of virtual visits in a general medicine practice
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Use of Videoconferencing for Depression Research: Enrollment, Retention, and Patient Satisfaction
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A Surgical Telemedicine Clinic in a Correctional Setting
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Depression in Parkinson’s disease: diagnosis and management
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PARKSERVICE: Home support and walking aid for people with Parkinson's disease.
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Reform Chronic Illness Care? Yes, We Can
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Delivering HIV subspecialty care in prisons utilizing telemedicine
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Web‐based clinical assessments for Parkinson's disease: Reliable and feasible
Grana, M. J., Bull, M. T., Venkataraman, V., Dorsey, E. R., & Biglan, K. (2012) · Movement Disorders · doi:10.1002/mds.25121 · Cited by 2 · see citing works
Self-citation
Flagged first, then by citations
2 of the 123 references couldn’t be matched to a known paper.
Research works printed but not linked: 2
- [116]State Coverage for Telehealth Services: National Conference of State Legislatures. [ http://www.ncsl.org/research/health/state-coverage-for-telehealth-services.aspx]
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National randomized controlled trial of virtual house calls for Parkinson disease
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Self-citationThe promise of telemedicine for chronic neurological disorders: the example of Parkinson's disease
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Self-citationPatient and Physician Perceptions of Virtual Visits for Parkinson's Disease: A Qualitative Study
Mammen, J. R., Elson, M. J., Java, J., Beck, C. A., Beran, D. B., Biglan, K., Boyd, C. M., Schmidt, P. N., Simone, R. B., Willis, A. W., et al. (2017) · Telemedicine Journal and e-Health · doi:10.1089/tmj.2017.0119 · Cited by 83 · see citing works
Self-citationDorsey, E. R., Achey, M. A., Beck, C. A., Beran, D. B., Biglan, K., Boyd, C. M., Schmidt, P. N., Simone, R. B., Willis, A. W., Galifianakis, N. B., et al. (2016) · Telemedicine Journal and e-Health · doi:10.1089/tmj.2015.0191 · Cited by 60 · see citing works
Self-citationvan Munster, M., Stümpel, J., Thieken, F., Pedrosa, D. J., Antonini, A., Côté, D., Fabbri, M., Ferreira, J. J., Růžička, E., Grimes, D., et al. (2021) · Journal of Personalized Medicine · doi:10.3390/jpm11070623 · Cited by 33 · see citing works
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Remote Assessment of Cognitive Function in Juvenile Neuronal Ceroid Lipofuscinosis (Batten disease)
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Telerehabilitation in Parkinson's disease: Influence of cognitive status
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Elson, M. J., Stevenson, E. A., Feldman, B., Lim, J., Beck, C. A., Beran, D. B., Schmidt, P. N., Biglan, K., Simone, R. B., Willis, A. W., et al. (2018) · Telemedicine Journal and e-Health · doi:10.1089/tmj.2017.0210 · Cited by 21 · see citing works
Self-citationNarrative review of telemedicine applications in decentralized research
Cummins, M. R., Soni, H., Ivanova, J., Ong, T., Barrera, J. F., Wilczewski, H., Welch, B. M., & Bunnell, B. E. (2024) · Journal of Clinical and Translational Science · doi:10.1017/cts.2024.3 · Cited by 14 · see citing works
Telehealth for Parkinson disease patients during the COVID-19 pandemic: the TeleParkinson study
Lima, D. P., Gomes, V. C., Júnior, A. B. V., de Assis, F. M. C., Oliveira, P. H. A., Cunha, L. C. V., Braga, I. C., Marques, M. L. S., Assunção, J. D. S., Damasceno, A. L. L., et al. (2022) · Arquivos de Neuro-Psiquiatria · doi:10.1055/s-0042-1758751 · Cited by 13 · see citing works
Acceptance of technology-based tools in a sample of Parkinson’s patients
Duroseau, N. H., Abramson, T. A., Pergament, K. M., Chan, V., Govindavari, J. P., Ciraco, C., Tegay, D. H., & Krishnamachari, B. (2016) · Chronic Illness · doi:10.1177/1742395316653453 · Cited by 13 · see citing works
Belastungen in der Betreuung von Parkinson-Patientinnen und - Patienten
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Advances in clinical trials for movement disorders
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A Novel Home-Based Telerehabilitation Program Targeting Fall Prevention in Parkinson Disease
Afshari, M., Hernandez, A. V., Joyce, J. M., Hauptschein, A. W., Trenkle, K., Stebbins, G. T., & Goetz, C. G. (2024) · Neurology Clinical Practice · doi:10.1212/cpj.0000000000200246 · Cited by 11 · see citing works
An equation to calculate UPDRS motor severity for online and rural assessments of Parkinson's
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Effect of Telerehabilitation in Parkinson Disease: A Systematic Review and Meta-Analysis
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Achey, M. A., Beck, C. A., Beran, D. B., Boyd, C. M., Schmidt, P. N., Willis, A. W., Riggare, S. S., Simone, R. B., Biglan, K., & Dorsey, E. R. (2016) · Trials · doi:10.1186/s13063-015-0984-7 · Cited by 4 · see citing works
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- Authors
- Achey, M. A., Beck, C. A., Beran, D. B., Boyd, C. M., Schmidt, P. N., Willis, A. W., Riggare, S. S., Simone, R. B., Biglan, K. M., & Dorsey, E. R.
- Affiliations
- University of Rochester Medicine (US)
- National Parkinson's Foundation (US)
- Johns Hopkins University (US)
- University of Pennsylvania (US)
- Karolinska Institutet (SE)
- Corresponding author
- Boyd, Cynthia M
- ORCID
- Venue
- Trials
- Published
- 2014-11-27
- Volume
- 15
- Issue
- 1
- Pages
- 465-465
- ISSN
- 1745-6215 (ISSN-L)
- PMC
- PMC4289172
- OpenAlex
- W2156371951
- Cited by
- 27
- References
- 123
- Citations by year
- 2026: 3 · 2025: 1 · 2024: 2 · 2023: 1 · 2022: 1 · 2021: 5 · 2020: 1 · 2019: 1 · 2018: 2 · 2017: 3 · 2016: 4 · 2015: 3
- FWCI
- 3.32
- Type
- journal article
- Language
- en
- Update notices
- correction (2016-01-05)
- Open access
- gold
- doi.org
- Licence
- Locations
- Trials (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, other-oa)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Funders
- Michael J. Fox Foundation for Parkinson's Research
- Robert Wood Johnson Foundation
- John A. Hartford Foundation
- Hartford Foundation for Public Giving
- National Parkinson Foundation
- Center for Health Care Strategies
- Amgen
- Commonwealth Foundation
- Biogen
- Patient-Centered Outcomes Research Institute (AD‐12‐11‐4701)
- Teva Pharmaceutical Industries
- University of Rochester (UL1TR000042)
- Boston Scientific Corporation
- Starr Foundation
- Davis Phinney Foundation
- Amarin Corporation
- Georgia Clinical and Translational Science Alliance
- Verizon Foundation
- H. Lundbeck A/S
- National Institutes of Health (UL1TR000042, TR000042)
- Agency for Healthcare Research and Quality
- Parkinsonfonden
- Avid Radiopharmaceuticals
- National Institute of Neurological Disorders and Stroke (K23NS081087)
- National Center for Advancing Translational Sciences
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Telemedicine and Telehealth Implementation
- Health Sciences › Medicine › Neurology › Parkinson's Disease Mechanisms and Treatments
- Social Sciences › Business, Management and Accounting › Organizational Behavior and Human Resource Management › Healthcare Systems and Technology
- Keywords
- Parkinson's disease, telemedicine, videoconferencing, health care access, care partners, caregiver burden, travel burden, quality of life, Parkinson's Disease Questionnaire, chronic disease, home care
- MeSH terms
- Clinical Protocols, Delivery of Health Care, Feasibility Studies, Health Services Accessibility, House Calls, Humans, Parkinson Disease, Quality of Life, Surveys and Questionnaires, Research Design, Time Factors, Transportation, United States, Treatment Outcome, Caregivers, Cost of Illness, Remote Consultation, Videoconferencing, Comparative Effectiveness Research
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