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Are treatment preferences relevant in response to serotonergic antidepressants and cognitive-behavioral therapy in depressed primary care patients? Results from a randomized controlled trial including a patients' choice arm
Open accessAbstract
BACKGROUND: Little is known about the influence of depressed patients' preferences and expectations about treatments upon treatment outcome. We investigated whether better clinical outcome in depressed primary care patients is associated with receiving their preferred treatment. METHODS: Within a randomized placebo-controlled single-centre 10-week trial with 5 arms (sertraline; placebo; cognitive-behavioral group therapy, CBT-G; moderated self-help group control; treatment with sertraline or CBT-G according to patients' choice), outcomes for 145 primary care patients with mild-to-moderate depressive disorders according to DSM-IV criteria were investigated. Preference for medication versus psychotherapy was assessed at screening using a single item. Post-baseline difference scores for the Hamilton Depression Rating Scale (HAMD-17) were used to assess treatment outcome (mixed-model repeated-measures regression analysis). RESULTS: Depressed patients receiving their preferred treatment (n = 63), whether sertraline or CBT-G, responded significantly better than those who did not receive their preferred therapy (n = 54; p = 0.001). The difference in outcome between both groups was 8.0 points on the HAMD-17 for psychotherapy and 2.9 points on the HAMD-17 for treatment with antidepressants. Results were not explained by differences in depression severity or dropout rates. CONCLUSIONS: Patients' relative preference for medication versus psychotherapy should be considered when offering a treatment because receiving the preferred treatment conveys an additional and clinically relevant benefit (HAMD-17: +2.9 points for drugs; +8.0 points for CBT-G) in outcome.
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“Other studies have shown that accommodating patient treatment can influence treatment outcomes (Adamson et al., 2008; Mergl et al., 2011; Williams et al., 2016).”
From Effects of patient-driven iCBT for anxiety in routine primary care and the relation between increased experience of empowerment and outcome: A randomized controlled trial (2021) · cites this paper as Mergl et al., 2011
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Cites
Hamilton, M. (1960) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.23.1.56 · Cited by 32,817
GPOWER: A general power analysis program
Erdfelder, E., Faul, F., & Buchner, A. (1996) · Behavior Research Methods, Instruments, & Computers · doi:10.3758/bf03203630 · Cited by 4,864
Gueorguieva, R., & Krystal, J. H. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.3.310 · Cited by 1,529
Applied Longitudinal Data Analysis for Epidemiology: A Practical Guide
Twisk, J. W. R. (2003) · Cited by 1,244
Cognitive Therapy vs Medications in the Treatment of Moderate to Severe Depression
DeRubeis, R. J., Hollon, S. D., Amsterdam, J. D., Shelton, R. C., Young, P. R., Salomon, R. M., O’Reardon, J. P., Lovett, M. L., Gladis, M. M., Brown, L. L., et al. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.4.409 · Cited by 989
Treatment preferences among depressed primary care patients
Dwight-Johnson, M., Sherbourne, C. D., Liao, D., & Wells, K. B. (2000) · Journal of General Internal Medicine · doi:10.1046/j.1525-1497.2000.08035.x · Cited by 478
Loh, A., Simon, D., Wills, C. E., Kriston, L., Niebling, W., & Härter, M. (2007) · Patient Education and Counseling · doi:10.1016/j.pec.2007.03.023 · Cited by 382
Bower, P., Byford, S., Sibbald, B., Ward, E. S., King, M., Lloyd, M., & Gabbay, M. (2000) · BMJ · doi:10.1136/bmj.321.7273.1389 · Cited by 350
Raue, P. J., Schulberg, H. C., Heo, M., Klimstra, S., & BRUCE, M. L. (2009) · Psychiatric Services · doi:10.1176/appi.ps.60.3.337 · Cited by 225
Assessing effectiveness of treatment of depression in primary care
Bedi, N., Chilvers, C. E. D., Churchill, D., Dewey, M. E., Duggan, C. F., Fielding, K., Gretton, V., Miller, P., Harrison, G., Lee, A., et al. (2000) · The British Journal of Psychiatry · doi:10.1192/bjp.177.4.312 · Cited by 188
Kocsis, J. H., Leon, A. C., Markowitz, J. C., Manber, R., Arnow, B. A., Klein, D. N., & Thase, M. E. (2009) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.08m04371 · Cited by 172
Hegerl, U., Hautzinger, M., Mergl, R., Kohnen, R., Schütze, M., Scheunemann, W., Allgaier, A., Coyne, J., & Henkel, V. (2010) · International Journal of Neuropsychopharmacology · doi:10.1017/s1461145709000224 · Cited by 120
Self-citationJorm, A. F., Christensen, H., Medway, J., Korten, A. E., Jacomb, P. A., & Rodgers, B. (2000) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s001270050230 · Cited by 110
Public Attitudes Towards Treatment of Depression: Effects of an Information Campaign
Hegerl, U., Althaus, D., & Stefanek, J. (2003) · Pharmacopsychiatry · doi:10.1055/s-2003-45115 · Cited by 94
Self-citationBower, P., King, M., Nazareth, I., Lampe, F. C., & Sibbald, B. (2005) · Social Science & Medicine · doi:10.1016/j.socscimed.2004.12.010 · Cited by 88
The Relation of Patients’ Treatment Preferences to Outcome in a Randomized Clinical Trial
Leykin, Y., DeRubeis, R. J., Gallop, R., Amsterdam, J. D., Shelton, R. C., & Hollon, S. D. (2007) · Behavior Therapy · doi:10.1016/j.beth.2006.08.002 · Cited by 87
Frequent Attenders in Primary Care: Impact of Medical, Psychiatric and Psychosomatic Diagnoses
Ferrari, S., Galeazzi, G. M., Mackinnon, A. J., & Rigatelli, M. (2008) · Psychotherapy and Psychosomatics · doi:10.1159/000142523 · Cited by 77
Fifty Years with the Hamilton Scales for Anxiety and Depression
Bech, P. (2009) · Psychotherapy and Psychosomatics · doi:10.1159/000214441 · Cited by 71
Pyne, J. M., ROST, K. M., Farahati, F., Tripathi, S. P., Smith, J. L., Williams, D. K., Fortney, J. C., & Coyne, J. C. (2004) · Psychological Medicine · doi:10.1017/s0033291704003332 · Cited by 70
Self-citationClinical Features and Functioning of Patients with Minor Depression
Howland, R. H., Schettler, P. J., Rapaport, M. H., Mischoulon, D., Schneider, T., Fasiczka, A. L., Delrahiem, K., Maddux, R. E., Lightfoot, M., & Nierenberg, A. A. (2008) · Psychotherapy and Psychosomatics · doi:10.1159/000151519 · Cited by 61
Dimensionen der Hamilton-Depressionsskala (HAMD)
Maier, W., Philipp, M., & Gerken, A. (1985) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/bf00386061 · Cited by 55
Hegerl, U., & Mergl, R. (2009) · Journal of Psychopharmacology · doi:10.1177/0269881109106930 · Cited by 54
Self-citationZum Einfluß der Psychotherapiemotivation auf den Psychotherapieverlauf
Schneider, W., Klauer, T., Janssen, P., & Tetzlaff, M. (1999) · Der Nervenarzt · doi:10.1007/s001150050428 · Cited by 29
Identifying Risk for Attrition during Treatment for Depression
Warden, D., Trivedi, M. H., Wisniewski, S. R., Lesser, I. M., Mitchell, J. R., Balasubramani, G. K., D, M. F. M., Shores‐Wilson, K., Stegman, D., & Rush, A. J. (2009) · Psychotherapy and Psychosomatics · doi:10.1159/000235977 · Cited by 26
Thornett, A. M. (2002) · PubMed · Cited by 17
Cited by
Sorted by citations
McHugh, R. K., Whitton, S. W., Peckham, A. D., Welge, J. A., & Otto, M. W. (2013) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.12r07757 · Cited by 800
Cleare, A., Pariante, C., Young, A., Anderson, I., Christmas, D., Cowen, P., Dickens, C., Ferrier, I., Geddes, J., Gilbody, S., et al. (2015) · Journal of Psychopharmacology · doi:10.1177/0269881115581093 · Cited by 759
Malhi, G. S., Bell, E., Bassett, D., Boyce, P., Bryant, R., Hazell, P., Hopwood, M., Lyndon, B., Mulder, R., Porter, R., et al. (2021) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/0004867420979353 · Cited by 614
Treatment selection in depression.
Cohen, Z. D., & DeRubeis, R. J. (2018) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-050817-084746 · Cited by 435
Client preferences affect treatment satisfaction, completion, and clinical outcome: a meta-analysis
Lindhiem, O., Bennett, C. B., Trentacosta, C. J., & McLear, C. (2014) · Clinical Psychology Review · doi:10.1016/j.cpr.2014.06.002 · Cited by 315
Metadata
- Authors
- Mergl, R., Henkel, V., Allgaier, A.-K., Kramer, D., Hautzinger, M., Kohnen, R., Coyne, J., & Hegerl, U.
- Affiliations
- Leipzig University (DE)
- Ludwig-Maximilians-Universität München (DE)
- University of Tübingen (DE)
- University of Pennsylvania Health System (US)
- Venue
- Psychotherapy and Psychosomatics
- Publisher
- S. Karger AG
- Published
- 2010-10-23
- Volume
- 80
- Issue
- 1
- Pages
- 39-47
- ISSN
- 0033-3190 (ISSN-L)
- 1423-0348
- OpenAlex
- W1966837287
- Cited by
- 126
- References
- 27
- Citations by year
- 2026: 3 · 2025: 4 · 2024: 1 · 2023: 5 · 2022: 2 · 2021: 10 · 2020: 8 · 2019: 9 · 2018: 12 · 2017: 7 · 2016: 6 · 2015: 16 · 2014: 9 · 2013: 10 · 2012: 16
- FWCI
- 11.98
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Psychotherapy and Psychosomatics (publishedVersion)
- PubMed (publishedVersion)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion, other-oa)
- Open access LMU (Ludwid Maxmilian's Universitat Munchen) (submittedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Keywords
- treatment preferences, patient choice, sertraline, cognitive behavioral therapy, group therapy, depression, primary care, antidepressants, psychotherapy, treatment outcomes, patient expectations
- MeSH terms
- Adult, Depressive Disorder, Female, Germany, Humans, Male, Middle Aged, Primary Health Care, Regression Analysis, Cognitive Behavioral Therapy, Treatment Outcome, Selective Serotonin Reuptake Inhibitors, Sertraline, Patient Preference
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