The DOI matches its Crossref record; 62 of the 62 references it cites were found in a registry or an index.
Activation of the Hypothalamic-Pituitary-Gonadal Axis in Infancy: Minipuberty
Abstract
The hypothalamic-pituitary-gonadal (HPG) axis is active in the midgestational foetus but silenced towards term because of the negative feedback effects mediated by the placental hormones. This restraint is removed at birth, leading to reactivation of the axis and an increase in gonadotrophin levels. Gonadotrophin levels are high during the first 3 months of life but decrease towards the age of 6 months except for FSH levels in girls that remain elevated until 3-4 years of age. After this, the HPG axis remains quiescent until puberty. The postnatal gonadotrophin surge results in gonadal activation in both sexes. In boys, testosterone levels rise to a peak at 1-3 months of age and then decline following LH levels. Postnatal HPG axis activation is associated with penile and testicular growth and therefore considered important for the development of male genitalia. In girls, elevated gonadotrophin levels result in the maturation of ovarian follicles and in an increase in oestradiol levels. Biological significance and possible long-term consequences of this minipuberty remain elusive, as do the mechanisms that silence the HPG axis until puberty. However, the first months of life provide a 'window of opportunity' for functional studies of the HPG axis prior to pubertal development.
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In the citing paper
“These concentrations then gradually decrease towards age 6 months, with the exception of FSH concentration in girls, which remains raised until age 3–4 years.”
From Pubertal development and regulation (2016) · cites this paper as [2]
In the citing paper
“This restraint is removed at birth, leading to reactivation of the axis and an increase in gonadotropin concentrations.2”
From Pubertal development and regulation (2016) · cites this paper as [2]
In the citing paper
“In boys, testosterone concentration rises to a peak at age 1–3 months, but then falls in conjunction with the falling LH concentration.2”
From Pubertal development and regulation (2016) · cites this paper as [2]
In the citing paper
“In human beings, the hypothalamic-pituitary-gonadal axis is active in the mid-gestational fetus, but silenced towards the end of gestation.”
From Pubertal development and regulation (2016) · cites this paper as [2]
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Cites
Andersson, A., Toppari, J., Haavisto, A., Petersen, J. H., Simell, T. T., Simell, O., & Skakkebæk, N. E. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.2.4603 · Cited by 411
Reyes, F. I., Boroditsky, R. S., Winter, J. S. D., & Faiman, C. (1974) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-38-4-612 · Cited by 385
Hagen, C. P., Aksglaede, L., Sørensen, K., Main, K. M., Boas, M., Cleemann, L., Holm, K., Gravholt, C. H., Andersson, A.-M., Pedersen, A. T., et al. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2010-0930 · Cited by 383
Winter, J. S. D., Hughes, I. A., Reyes, F. I., & Faiman, C. (1976) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-42-4-679 · Cited by 367
Winter, J. S. D., Faiman, C., Hobson, W. C., PRASAD, A. V., & Reyes, F. I. (1975) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-40-4-545 · Cited by 326
Aksglæde, L., Sørensen, K., Boas, M., Mouritsen, A., Hagen, C. P., Jensen, R. B., Petersen, J. H., Linneberg, A. R., Andersson, A., Main, K. M., et al. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2010-1207 · Cited by 278
Cortes, D., Müller, J., & Skakkebæk, N. E. (1987) · International Journal of Andrology · doi:10.1111/j.1365-2605.1987.tb00358.x · Cited by 267
CLEMENTS, J. A., Reyes, F. I., Winter, J. S. D., & Faiman, C. (1976) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-42-1-9 · Cited by 267
Boas, M., Boisen, K. A., Virtanen, H., Kaleva, M., Suomi, A.-M., Schmidt, I. M., Damgaard, I., Kai, C. M., Chellakooty, M., Skakkebaek, N., et al. (2006) · European Journal of Endocrinology · doi:10.1530/eje.1.02066 · Cited by 226
Bergadá, I., Milani, C., Bedecarrás, P., Andreone, L., Ropelato, M. G., Gottlieb, S., Bergadá, C., Campo, S., & Rey, R. A. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-1079 · Cited by 219
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Souza, G. S., Freitas, I., de Souza, J. C., Miraglia, S. M., & Paccola, C. C. (2023) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2023.116525 · Cited by 3
Trevisani, V., Palandri, L., Righi, B., Maione, D., Pasquale, L. D., Tagliafico, E., Grisolia, C., Tagliazucchi, M., Predieri, B., Iughetti, L., et al. (2024) · Journal of Endocrinological Investigation · doi:10.1007/s40618-024-02493-1 · Cited by 2
McCarthy, M. M. (2017) · Principles of Gender-Specific Medicine · doi:10.1016/b978-0-12-803506-1.00033-4 · Cited by 3
Davoodi, M. A., Ghobadi, F., Mahmoudi, G., & Almasi‐Hashiani, A. (2022) · Archives of Iranian Medicine · doi:10.34172/aim.2022.09 · Cited by 3
Exaggerated mini-puberty in a preterm girl: a case report and review of literature
Lattuada, M., Molinari, S., Nicolosi, M. L., Doni, D., Lui, C., Passoni, P., Polizzi, S., Ocello, L., Evasi, V., Calia, M., et al. (2022) · Journal of Pediatric Endocrinology and Metabolism · doi:10.1515/jpem-2022-0179 · Cited by 3
Sex differences in the brain: Focus on developmental mechanisms
McCarthy, M. M. (2023) · Principles of Gender-Specific Medicine · doi:10.1016/b978-0-323-88534-8.00007-9 · Cited by 4
Imaizumi, J., Kamada, S., Taniguchi, M., Sugimoto, T., Maeda, T., Arakaki, R., Yamamoto, S., Shirakawa, A., Mineda, A., Yoshida, A., et al. (2023) · Nutrients · doi:10.3390/nu15122768 · Cited by 3
Boncompagni, A., Pietrella, E., Passini, E., Grisolia, C., Tagliazucchi, M., Tagliafico, E., Lugli, L., Berardi, A., Iughetti, L., & Lucaccioni, L. (2023) · Journal of Clinical Research in Pediatric Endocrinology · doi:10.4274/jcrpe.galenos.2023.2023-4-9 · Cited by 3
Gacemer, H., Tosun, B. G., Helvacıoğlu, D., Yaman, A., Abalı, Z., Haliloglu, B., Turan, S., Haklar, G., Bereket, A., & Guran, T. (2023) · European Journal of Pediatrics · doi:10.1007/s00431-023-05393-3 · Cited by 3
Kulle, A. E., Caliebe, A., Lamprecht, T., Reinehr, T., Ŝimić-Schleicher, G., Schulz, E., Kleber, M., Rothermel, J., Heger, S., Hiort, O., et al. (2024) · European Journal of Endocrinology · doi:10.1093/ejendo/lvae046 · Cited by 3
Postnatal Dysregulation of Androgens in Extremely Preterm Male Infants
Nilsson, A., Sjöbom, U., Landin, A., Andersson, M. X., Ryberg, H., Pivodic, A., Löfqvist, C., Sävman, K., POUTANEN, M. H., Ohlsson, C., et al. (2024) · Journal of the Endocrine Society · doi:10.1210/jendso/bvae179 · Cited by 3
Österbrand, M., Fors, H., & Norjavaara, E. (2019) · Hormone Research in Paediatrics · doi:10.1159/000500356 · Cited by 3
Österbrand, M., Fors, H., Allvin, K., & Norjavaara, E. (2017) · Hormone Research in Paediatrics · doi:10.1159/000470841 · Cited by 3
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Beylerli, O., Фанилевич, Г. И., & Beilerli, A. (2019) · Creative Surgery and Oncology · doi:10.24060/2076-3093-2019-9-2-138-143 · Cited by 3
Personalized Health Care for Orofacial Cleft Patients
van der Horst, C. M. A. M. (2021) · Springer eBooks · doi:10.1007/978-3-030-63746-0_6 · Cited by 3
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Barbieri, F., Inzaghi, E., Nicoletti, M. C., Cassio, A., Grandone, A., SANCTIS, L. D., & Bizzarri, C. (2021) · Minerva Pediatrics · doi:10.23736/s2724-5276.21.06511-3 · Cited by 3
Kharazi, U., Keyhanmanesh, ., Hamidian, G., Ghaderpour, S., & Ghiasi, R. (2021) · PubMed Central · doi:10.22038/ijbms.2021.58740.13048 · Cited by 3
The Origins of Gender, not Sex: Evolution and the Reproductive AxisPreprint
Woodhill, B. M., Samuels, C. A., & Jamieson, G. A. (2024) · doi:10.33774/coe-2020-k7gt1-v10 · Cited by 2
Metadata
- Authors
- Kuiri-Hänninen, T., Sankilampi, U., & Dunkel, L.
- Affiliations
- University of Eastern Finland (FI)
- Queen Mary University of London (GB)
- Venue
- Hormone Research in Paediatrics
- Publisher
- S. Karger AG
- Published
- 2014
- Volume
- 82
- Issue
- 2
- Pages
- 73-80
- ISSN
- 1663-2818 (ISSN-L)
- 1663-2826
- OpenAlex
- W2096395933
- Cited by
- 470
- References
- 62
- Citations by year
- 2026: 35 · 2025: 32 · 2024: 46 · 2023: 42 · 2022: 50 · 2021: 54 · 2020: 54 · 2019: 45 · 2018: 33 · 2017: 39 · 2016: 28 · 2015: 9 · 2014: 3
- FWCI
- 4.12
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Hormone Research in Paediatrics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Sexual Differentiation and Disorders
- Health Sciences › Medicine › Reproductive Medicine › Reproductive Biology and Fertility
- Keywords
- hypothalamic-pituitary-gonadal axis, minipuberty, infancy, gonadotropins, follicle-stimulating hormone, luteinizing hormone, testosterone, estradiol, placental hormones, negative feedback, male genital development, ovarian follicle maturation, puberty
- MeSH terms
- Child Development, Estradiol, Female, Genitalia, Male, Gonadotropins, Ovarian Follicle, Humans, Hypothalamo-Hypophyseal System, Infant, Newborn, Male, Testosterone
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