Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 473

The DOI matches its Crossref record; 75 of the 75 references it cites were found in a registry or an index.

Premature Adrenarche - A Common Condition with Variable Presentation

Utriainen, Pauliina, Laakso, Saila, Liimatta, Jani, Jääskeläinen, Jarmo, Voutilainen, Raimo·2015·Hormone Research in Paediatrics
DOI 10.1159/000369458
Open this paper in CoChat — free account

Abstract

Adrenarche refers to a maturational increase in the secretion of adrenal androgen precursors, mainly dehydroepiandrosterone (DHEA) and its sulfate (DHEAS). In premature adrenarche (PA), clinical signs of androgen action appear before the age of 8/9 years in girls/boys, concurrently with the circulating DHEA(S) concentrations above the usually low prepubertal level. The most pronounced sign of PA is the appearance of pubic/axillary hair, but also other signs of androgen effect (adult type body odor, acne/comedones, greasy hair, accelerated statural growth) are important to recognize. PA children are often overweight and taller than their peers, and the higher prevalence of PA in girls than in boys is probably explained by higher female adiposity and peripheral DHEA(S) conversion to active androgens. PA diagnosis requires exclusion of other causes of androgen excess: congenital adrenal hyperplasia, androgen-producing tumors, precocious puberty, and exogenous source of androgens. PA has been linked with unfavorable metabolic features including hyperinsulinism, dyslipidemia, and later-appearing ovarian hyperandrogenism. Although this common condition is usually benign, PA children with additional risk factors including obesity should be followed up, with the focus on weight and lifestyle. Long-term follow-up studies are warranted to clarify if the metabolic changes detected in PA children persist until adulthood.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1159/000369458

Cites

75 of 75 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 75 references

Research works printed but not linked: 6

  1. 10.1210/jcem.83.10.5205 · doi:10.1210/jcem.83.10.5205 · Paper page
  2. 10.1210/jc.86.9.4536 · doi:10.1210/jc.86.9.4536
  3. 10.1210/jcem.74.2.1309831 · doi:10.1210/jcem.74.2.1309831 · Paper page
  4. 10.1159/000308178 · doi:10.1159/000308178
  5. 10.1210/jc.87.1.398 · doi:10.1210/jc.87.1.398
  6. 10.1210/jc.86.11.5269 · doi:10.1210/jc.86.11.5269

Cited by

See all 473

Metadata

Authors
Utriainen, P., Laakso, S., Liimatta, J., Jääskeläinen, J., & Voutilainen, R.
Venue
Hormone Research in Paediatrics
Publisher
S. Karger AG
Published
2015
Volume
83
Issue
4
Pages
221-231
ISSN
  • 1663-2818 (ISSN-L)
  • 1663-2826
DOI
10.1159/000369458
OpenAlex
W1994216334
Cited by
473
References
75
FWCI
32.40
Type
journal article
Language
en
Open access
closed
Licence

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Premature Adrenarche - A Common Condition with Variable Presentation. https://app.cochat.ai/papers/10.1159/000369458
The paper
Utriainen, P., Laakso, S., Liimatta, J., Jääskeläinen, J., & Voutilainen, R. (2015). Premature Adrenarche - A Common Condition with Variable Presentation. Hormone Research in Paediatrics. https://doi.org/10.1159/000369458

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.