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The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.

Heart Rate, Life Expectancy and the Cardiovascular System: Therapeutic Considerations

Open access
Boudoulas, Konstantinos Dean, Borer, Jeffrey S., Boudoulas, Harisios·2015·Cardiology

Abstract

It has long been known that life span is inversely related to resting heart rate in most organisms. This association between heart rate and survival has been attributed to the metabolic rate, which is greater in smaller animals and is directly associated with heart rate. Studies have shown that heart rate is related to survival in apparently healthy individuals and in patients with different underlying cardiovascular diseases. A decrease in heart rate due to therapeutic interventions may result in an increase in survival. However, there are many factors regulating heart rate, and it is quite plausible that these may independently affect life expectancy. Nonetheless, a fast heart rate itself affects the cardiovascular system in multiple ways (it increases ventricular work, myocardial oxygen consumption, endothelial stress, aortic/arterial stiffness, decreases myocardial oxygen supply, other) which, in turn, may affect survival. In this brief review, the effects of heart rate on the heart, arterial system and survival will be discussed.

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Metadata

Authors
Boudoulas, K. D., Borer, J. S., & Boudoulas, H.
Venue
Cardiology
Publisher
S. Karger AG
Published
2015
Volume
132
Issue
4
Pages
199-212
ISSN
  • 0008-6312 (ISSN-L)
  • 1421-9751
OpenAlex
W1811184201
Cited by
1,938
References
11
FWCI
114.43
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Heart Rate, Life Expectancy and the Cardiovascular System: Therapeutic Considerations. https://app.cochat.ai/papers/10.1159/000435947
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Boudoulas, K. D., Borer, J. S., & Boudoulas, H. (2015). Heart Rate, Life Expectancy and the Cardiovascular System: Therapeutic Considerations. Cardiology. https://doi.org/10.1159/000435947

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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