Chromium Supplementation and the Effects on Metabolic Status in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial

Insulin Resistance and the Polycystic Ovary Syndrome Revisited: An Update on Mechanisms and Implications

Diamanti-Kandarakis, E., & Dunaif, A. (2012) · Endocrine Reviews · doi:10.1210/er.2011-1034 · Cited by 1,947 · see citing works

Elevated Intakes of Supplemental Chromium Improve Glucose and Insulin Variables in Individuals With Type 2 Diabetes

Anderson, R. A., Cheng, N., Bryden, N. A., Polansky, M. M., Cheng, N., Chi, J., & Feng, J. (1997) · Diabetes · doi:10.2337/diab.46.11.1786 · Cited by 609 · see citing works

Polycystic ovary syndrome and cardiovascular disease: a premature association?

Legro, R. S. (2003) · Endocrine Reviews · doi:10.1210/er.2003-0004 · Cited by 466 · see citing works

Limitations in the Use of Indices Using Glucose and Insulin Levels to Predict Insulin Sensitivity

Pisprasert, V., Ingram, K. H., Lopez-Davila, M. F., Munoz, A. J., & Garvey, W. T. (2013) · Diabetes Care · doi:10.2337/dc12-0840 · Cited by 302 · see citing works

Oral Chromium Picolinate Improves Carbohydrate and Lipid Metabolism and Enhances Skeletal Muscle Glut-4 Translocation in Obese, Hyperinsulinemic (JCR-LA Corpulent) Rats

Cefalu, W. T., Wang, Z. Q., Zhang, X. H., Baldor, L. C., & Russell, J. C. (2002) · Journal of Nutrition · doi:10.1093/jn/132.6.1107 · Cited by 227 · see citing works

Chromium Picolinate Supplementation Attenuates Body Weight Gain and Increases Insulin Sensitivity in Subjects With Type 2 Diabetes

Martin, J., Wang, Z. Q., Zhang, X. H., Wachtel, D., Vólaufová, J., Matthews, D. E., & Cefalu, W. T. (2006) · Diabetes Care · doi:10.2337/dc06-0254 · Cited by 207 · see citing works

Supplemental-chromium effects on glucose, insulin, glucagon, and urinary chromium losses in subjects consuming controlled low-chromium diets

Anderson, R., Polansky, M. M., Bryden, N., & Canary, J. (1991) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/54.5.909 · Cited by 198 · see citing works

Effect of chromium niacinate and chromium picolinate supplementation on lipid peroxidation, TNF-α, IL-6, CRP, glycated hemoglobin, triglycerides, and cholesterol levels in blood of streptozotocin-treated diabetic rats

Jain, S. K., Rains, J., & Croad, J. L. (2007) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.05.019 · Cited by 161 · see citing works

Role of chromium supplementation in Indians with type 2 diabetes mellitus

Ghosh, D., Bhattacharya, B., Mukherjee, B., Manna, B., Sinha, M., Chowdhury, J., & Chowdhury, S. (2002) · The Journal of Nutritional Biochemistry · doi:10.1016/s0955-2863(02)00220-6 · Cited by 140 · see citing works

DASH Diet, Insulin Resistance, and Serum hs-CRP in Polycystic Ovary Syndrome: A Randomized Controlled Clinical Trial

Asemi, Z., & Esmaillzadeh, A. (2015) · Hormone and Metabolic Research · doi:10.1055/s-0034-1376990 · Cited by 134 · see citing works

Assessment of insulin sensitivity from measurements in the fasting state and during an oral glucose tolerance test in polycystic ovary syndrome and menopausal patients.

Ciampelli, M., Leoni, F., Cucinelli, F., Mancuso, S., Panunzi, S., Gaetano, A. D., & Lanzone, A. (2005) · Journal of Clinical Endocrinology and Metabolism · doi:10.1210/jc.2004-0410 · Cited by 127 · see citing works

Beneficial effect of chromium supplementation on glucose, HbA1C and lipid variables in individuals with newly onset type-2 diabetes

Sharma, S., Agrawal, R. P., Choudhary, M., Jain, S., Goyal, S., & Agarwal, V. (2011) · Journal of Trace Elements in Medicine and Biology · doi:10.1016/j.jtemb.2011.03.003 · Cited by 120 · see citing works

The effects of old, new and emerging medicines on metabolic aberrations in PCOS

Bargiota, Α., & Diamanti‐Kandarakis, E. (2012) · Therapeutic Advances in Endocrinology and Metabolism · doi:10.1177/2042018812437355 · Cited by 118 · see citing works

Metabolic response to selenium supplementation in women with polycystic ovary syndrome: a randomized, double‐blind, placebo‐controlled trial

Jamilian, M., Razavi, M., Fakhrieh-Kashan, Z., Ghandi, Y., Bagherian, T., & Asemi, Z. (2014) · Clinical Endocrinology · doi:10.1111/cen.12699 · Cited by 103 · see citing works

Altered Trace Mineral Milieu Might Play An Aetiological Role in the Pathogenesis of Polycystic Ovary Syndrome

Chakraborty, P., Ghosh, S., Goswami, S. K., Kabir, S. N., Chakravarty, B., & Jana, K. (2013) · Biological Trace Element Research · doi:10.1007/s12011-012-9592-5 · Cited by 99 · see citing works

Effect of Chromium Supplementation on Blood Glucose and Lipid Levels in Type 2 Diabetes Mellitus Elderly Patients

Rabinovitz, Friedensohn, Leibovitz, Gabay, Rocas, & Habot (2004) · International Journal for Vitamin and Nutrition Research · doi:10.1024/0300-9831.74.3.178 · Cited by 90 · see citing works

Chromium Supplementation Does Not Improve Glucose Tolerance, Insulin Sensitivity, or Lipid Profile

Gunton, J. E., Cheung, N. W., Hitchman, R., Hams, G., O’Sullivan, C., Foster‐Powell, K., & McElduff, A. (2005) · Diabetes Care · doi:10.2337/diacare.28.3.712 · Cited by 73 · see citing works

Updates on the myo-inositol plus D-chiro-inositol combined therapy in polycystic ovary syndrome

Unfer, V., & Porcaro, G. (2014) · Expert Review of Clinical Pharmacology · doi:10.1586/17512433.2014.925795 · Cited by 67 · see citing works

Effect of Chromium on Glucose and Lipid Profiles in Patients with Type 2 Diabetes; A Meta-analysis Review of Randomized Trials

Abdollahi, M. R., Farshchi, A., Nikfar, S., & Seyedifar, M. (2013) · Journal of Pharmacy & Pharmaceutical Sciences · doi:10.18433/j3g022 · Cited by 67 · see citing works

Biomarkers and insulin sensitivity in women with P olycystic Ovary Syndrome: Characteristics and predictive capacity

Cassar, S., Teede, H. J., Harrison, C. L., Joham, A. E., Moran, L., & Stepto, N. K. (2014) · Clinical Endocrinology · doi:10.1111/cen.12619 · Cited by 60 · see citing works

Definition of insulin resistance using the homeostasis model assessment (HOMA-IR) in IVF patients diagnosed with polycystic ovary syndrome (PCOS) according to the Rotterdam criteria

Alebić, M. Š., Bulum, T., Stojanović, N., & Duvnjak, L. S. (2014) · Endocrine · doi:10.1007/s12020-014-0182-5 · Cited by 56 · see citing works

Cardiovascular Risk and Subclinical Cardiovascular Disease in Polycystic Ovary Syndrome

Studen, K. B., Sever, M. J., & Pfeifer, M. (2012) · Frontiers of hormone research · doi:10.1159/000341838 · Cited by 51 · see citing works

Chromium Nicotinate Has No Effect on Insulin Sensitivity, Glycemic Control, and Lipid Profile in Subjects with Type 2 Diabetes

Guimarães, M. M., Carvalho, A. C. M. S., & Silva, M. S. (2013) · Journal of the American College of Nutrition · doi:10.1080/07315724.2013.816598 · Cited by 33 · see citing works

Effect of Chromium-Enriched Yeast on Fasting Plasma Glucose, Glycated Haemoglobin and Serum Lipid Levels in Patients with Type 2 Diabetes Mellitus Treated with Insulin

Ráček, J., Sindberg, C., Moesgaard, S., Mainz, J., Fábry, J., Müller, L., & Rácová, K. (2013) · Biological Trace Element Research · doi:10.1007/s12011-013-9758-9 · Cited by 28 · see citing works

Metformin versus chromium picolinate in clomiphene citrate-resistant patients with PCOs: A double-blind randomized clinical trial.

Amooee, S., Parsanezhad, M. E., Shirazi, M. R., Alborzi, S., & Samsami, A. (2013) · Europe PMC (PubMed Central) · Cited by 27 · see citing works

Chromium supplementation in non-obese non-diabetic subjects is associated with a decline in insulin sensitivity

Masharani, U. B., Gjerde, C., McCoy, S., Maddux, B. A., Hessler, D., Goldfine, I. D., & YOUNGREN, J. F. (2012) · BMC Endocrine Disorders · doi:10.1186/1472-6823-12-31 · Cited by 26 · see citing works

Validation of a simplified method to assess hirsutism in the Iranian population

Tehrani, F. R., Minooee, S., & Azizi, F. (2013) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2013.12.008 · Cited by 24 · see citing works

Chromium Status and Glucose Tolerance in Saudi Men With and Without Coronary Artery Disease

Alissa, E. M., Bahijri, S., Ahmed, W. H., Alama, N., & Ferns, G. A. (2009) · Biological Trace Element Research · doi:10.1007/s12011-009-8365-2 · Cited by 21 · see citing works

Chromium Therapy for Insulin Resistance Associated with HIV-Disease

Nurlan, S. A. S. M. M. (2013) · Journal of AIDS & Clinical Research · doi:10.4172/2155-6113.1000239 · Cited by 9 · see citing works

Nutritional Supplements and Complementary Therapies in Polycystic Ovary Syndrome

Alesi, S., Ee, C., Moran, L., Rao, V. S., & Mousa, A. (2021) · Advances in Nutrition · doi:10.1093/advances/nmab141 · Cited by 180 · see citing works

Nutrition in Gynecological Diseases: Current Perspectives

Ciebiera, M., Esfandyari, S., Siblini, H., Prince, L., Elkafas, H., Wojtyła, C., Al-Hendy, A. A., & Ali, M. K. (2021) · Nutrients · doi:10.3390/nu13041178 · Cited by 136 · see citing works

The Effect of Nutrient Supplementation in Management of Polycystic Ovary Syndrome Associated Metabolic Dysfunctions: A Critical Review

Günalan, E., Yaba, A., & Yılmaz, B. (2018) · Journal of the Turkish-German Gynecological Association · doi:10.4274/jtgga.2018.0077 · Cited by 74 · see citing works

Chromium supplementation and polycystic ovary syndrome: A systematic review and meta-analysis

Fazelian, S., Rouhani, M. H., Saraf‐Bank, S., & Amani, R. (2017) · Journal of Trace Elements in Medicine and Biology · doi:10.1016/j.jtemb.2017.04.008 · Cited by 67 · see citing works

The Effects of Chromium Supplementation on Endocrine Profiles, Biomarkers of Inflammation, and Oxidative Stress in Women with Polycystic Ovary Syndrome: a Randomized, Double-Blind, Placebo-Controlled Trial

Jamilian, M., Bahmani, F., Siavashani, M. A., Mazloomi, M., Asemi, Z., & Esmaillzadeh, A. (2015) · Biological Trace Element Research · doi:10.1007/s12011-015-0570-6 · Cited by 57 · see citing works

The Influences of Chromium Supplementation on Metabolic Status in Patients with Type 2 Diabetes Mellitus and Coronary Heart Disease

Farrokhian, A., Mahmoodian, M., Bahmani, F., Amirani, E., Shafabakhsh, R., & Asemi, Z. (2019) · Biological Trace Element Research · doi:10.1007/s12011-019-01783-7 · Cited by 55 · see citing works

The Influences of Chromium Supplementation on Glycemic Control, Markers of Cardio-Metabolic Risk, and Oxidative Stress in Infertile Polycystic ovary Syndrome Women Candidate for In vitro Fertilization: a Randomized, Double-Blind, Placebo-Controlled Trial

Jamilian, M., Modarres, S. Z., Siavashani, M. A., Karimi, M., Mafi, A., Ostadmohammadi, V., & Asemi, Z. (2018) · Biological Trace Element Research · doi:10.1007/s12011-017-1236-3 · Cited by 42 · see citing works

The Effects of Supplementation with Chromium on Insulin Resistance Indices in Women with Polycystic Ovarian Syndrome: A Systematic Review and Meta-Analysis of Randomized Clinical Trials

Heshmati, J., Samani, R. O., Vesali, S., Maroufizadeh, S., Rezaeinejad, M., Razavi, M., & Sepidarkish, M. (2018) · Hormone and Metabolic Research · doi:10.1055/s-0044-101835 · Cited by 38 · see citing works

Effects of Chromium and Carnitine Co-supplementation on Body Weight and Metabolic Profiles in Overweight and Obese Women with Polycystic Ovary Syndrome: a Randomized, Double-Blind, Placebo-Controlled Trial

Jamilian, M., Foroozanfard, F., Kavossian, E., Kia, M., Aghadavod, E., Amirani, E., & Asemi, Z. (2019) · Biological Trace Element Research · doi:10.1007/s12011-019-01720-8 · Cited by 36 · see citing works

Heavy Metals and Essential Elements in Association with Oxidative Stress in Women with Polycystic Ovary Syndrome—A Systematic Review

Srnovršnik, T., Virant‐Klun, I., & Pinter, B. (2023) · Antioxidants · doi:10.3390/antiox12071398 · Cited by 34 · see citing works

Changes in serum heavy metals in polycystic ovary syndrome and their association with endocrine, lipid-metabolism, inflammatory characteristics and pregnancy outcomes

Zhang, C., Xu, L., Zhao, Y., & Wang, Y. (2022) · Reproductive Toxicology · doi:10.1016/j.reprotox.2022.05.002 · Cited by 30 · see citing works

Chromium supplementation in women with polycystic ovary syndrome: Systematic review and meta‐analysis

Tang, X., Sun, Z., & Gong, L. (2017) · Journal of obstetrics and gynaecology research · doi:10.1111/jog.13462 · Cited by 27 · see citing works

Nutritional and herbal interventions for polycystic ovary syndrome (PCOS): a comprehensive review of dietary approaches, macronutrient impact, and herbal medicine in management

Muhammed Saeed, A. A., Noreen, S., Awlqadr, F. H., Farooq, M. I., Qadeer, M., Rai, N., Farag, H. A., & Saeed, M. N. (2025) · Journal of Health, Population and Nutrition · doi:10.1186/s41043-025-00899-y · Cited by 29 · see citing works

The effects of chromium supplementation on lipidprofile in humans: A systematic review and meta-analysis ofrandomized controlled trials

Tarrahi, M. J., Tarrahi, M.-A., Rafiee, M., & Mansourian, M. (2020) · Pharmacological Research · doi:10.1016/j.phrs.2020.105308 · Cited by 23 · see citing works

Chromium supplementation does not improve weight loss or metabolic and hormonal variables in patients with polycystic ovary syndrome: A systematic review

Maleki, V., Izadi, A., Farsad-Naeimi, A., & Alizadeh, M. (2018) · Nutrition Research · doi:10.1016/j.nutres.2018.04.003 · Cited by 20 · see citing works

Efficacy of antioxidant supplementation in improving endocrine, hormonal, inflammatory, and metabolic statuses of PCOS: a meta-analysis and systematic review

He, J., Deng, R., Wei, Y., Zhang, S., Su, M., Tang, M., Wang, J., Nong, W., & Lei, X. (2024) · Food & Function · doi:10.1039/d3fo02824k · Cited by 19 · see citing works

Chromium supplements in health and disease

Costello, R. B., Dwyer, J. T., & Merkel, J. M. (2019) · Elsevier eBooks · doi:10.1016/b978-0-444-64121-2.00007-6 · Cited by 19 · see citing works

Nutritional support and dietary interventions for women with polycystic ovary syndrome

Papavasiliou, K., & Papakonstantinou, E. (2017) · Nutrition and Dietary Supplements · doi:10.2147/nds.s119738 · Cited by 17 · see citing works

Comparison of nutritional supplements in improving glycolipid metabolism and endocrine function in polycystic ovary syndrome: a systematic review and network meta-analysis

Hu, X., Wang, W., Su, X., Peng, H., Tan, Z., Li, Y.-Q., & Huang, Y. (2023) · PeerJ · doi:10.7717/peerj.16410 · Cited by 18 · see citing works

The effect of maternal chromium status on lipid metabolism in female elderly mice offspring and involved molecular mechanism

Zhang, Q., Sun, X., Xiao, X., Zheng, J., Li, M., Yu, M., Ping, F., Wang, Z., Qi, C., Wang, T., et al. (2017) · Bioscience Reports · doi:10.1042/bsr20160362 · Cited by 13 · see citing works

The effectiveness of nutritional supplements in improving polycystic ovary syndrome in women: a systematic review and network meta-analysis

Zhao, G., Fan, Y., Li, R., Huang, Y. S., Li, W., Zhao, Y., Zhou, M., & He, J. (2025) · Reproductive Biology and Endocrinology · doi:10.1186/s12958-025-01409-9 · Cited by 12 · see citing works

The Linkage “Body Mass Index-Insomnia Levels-Eating Disorder Flexibility” in Italian Nurses During the Covid-19 Outbreak: A Psychoendocrinological Employment Disease

Vitale, E., Galatola, V., Mea, R., Dio, F. D., & Canonico, A. (2021) · Endocrine Metabolic & Immune Disorders - Drug Targets · doi:10.2174/1871530321666210715125939 · Cited by 11 · see citing works

The Possibilities of Using Chromium Salts as an Agent Supporting Treatment of Polycystic Ovary Syndrome

Piotrowska, A., Pilch, W., Czerwińska‐Ledwig, O., Zuziak, R., Siwek, A., Wolak, M., & Nowak, G. (2019) · Biological Trace Element Research · doi:10.1007/s12011-019-1654-5 · Cited by 9 · see citing works

An overview on effects of micronutrients and macronutrients interventions in management of polycystic ovary syndrome

Naz, M. S. G., Jahanfar, S., & Tehrani, F. R. (2022) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2022.11.007 · Cited by 7 · see citing works

A Chronic Inflammatory Inductive Condition in the Nursing Profession: A Scoping Review

Vitale, E. (2022) · Endocrine Metabolic & Immune Disorders - Drug Targets · doi:10.2174/1871530322666220516163936 · Cited by 4 · see citing works

How important are elements in polycystic ovary syndrome? Should they be supplemented? A systematic review

Pokorska‐Niewiada, K., Ziętek, M., Świątkowska-Freund, M., & Szczuko, M. (2023) · Ginekologia Polska · doi:10.5603/gpl.96864 · Cited by 4 · see citing works

Therapeutic effects of chromium supplementation on women with polycystic ovarian syndrome: A systematic review and meta-analysis

Hamsho, M., Ranneh, Y., & Fadel, A. (2025) · Endocrinología Diabetes y Nutrición (English ed ) · doi:10.1016/j.endien.2025.501578 · Cited by 2 · see citing works

The effect of nutrients on metabolic disorders associated with polycystic ovary syndrome

Овчаренко, Д. В., Popov, A. A., Коваль, А. А., Tyurina, S. S., & Fedorov, А. А. (2020) · Russian Bulletin of Obstetrician-Gynecologist · doi:10.17116/rosakush20202004127 · Cited by 2 · see citing works

Evidence-Based Nutritional Supplementation in Polycystic Ovary Syndrome: A Comprehensive Review of Clinical Outcomes, Mechanisms, and Recommendations

Andres-Montenegro, N., Molina-Gutierrez, S., & Murillo, O. I. N. (2025) · Bionatura journal : · doi:10.70099/bj/2025.02.02.13 · Cited by 1 · see citing works

Dietary Supplements, Phytotherapy and Chinese Herbal Medicine in PCOS

Wu, X., & Ng, E. H. Y. (2018) · Springer eBooks · doi:10.1007/978-3-319-45534-1_14

Efeito da suplementação de cromo na resistência insulínica, na dislipidemia, na inflamação e no estresse oxidativo de pessoas HIV-positivo com lipodistrofia

Pansani, M. C. (2018) · doi:10.11606/t.17.2018.tde-24042018-174804

Polikistik Over Sendromu ve Ağırlık Yönetimi Arasındaki İlişkinin İncelenmesi

Sarıyer, E. T., & Burcu Merve, A. K. S. U. (2021) · Süleyman Demirel Üniversitesi Sağlık Bilimleri Dergisi · doi:10.22312/sdusbed.854552 · Cited by 4 · see citing works

MICRONUTRIENT DEFICIENCY IN THE PATHOGENESIS OF INSULIN RESISTANCE AND WAYS TO CORRECT IT

Mykytyuk, M. (2021) · PROBLEMS OF ENDOCRINE PATHOLOGY · doi:10.21856/j-pep.2021.4.18

Therapeutic effects of chromium supplementation on women with polycystic ovarian syndrome: A systematic review and meta-analysis

Hamsho, M., Ranneh, Y., & Fadel, A. (2025) · Endocrinología Diabetes y Nutrición · doi:10.1016/j.endinu.2025.501578

¿Son efectivos los compuestos bioactivos destinados a la pérdida de peso?: una revisión sistemática

Betancur-Quintero, J. A., & Aristizábal, A. (2025) · Revista Universidad Católica de Oriente · doi:10.47286/01211463.620

The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis

Yang, L., Gao, Y., Zhao, W., Qi, Y., Duo, X., & Wang, H. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1683556

Effectiveness of mineral supplements (magnesium, chromium, zinc, selenium, chromium picolinate) in reducing insulin resistance in polycystic ovary syndrome: a meta-analysis of randomized controlled trials

Ye, J., Cen, S., Qi, Q., Wang, C., Wang, J., Wang, J., Yaping, G., & Wang, J. (2026) · BMC Endocrine Disorders · doi:10.1186/s12902-025-02158-x

Micronutrients in polycystic ovary syndrome: molecular pathways, deficiencies, and therapeutic potential

Natarajan, M., Shweatha, H. E., & Nataraj, R. (2026) · Frontiers in Endocrinology · doi:10.3389/fendo.2026.1766838

Therapeutic effects of chromium supplementation on women with polycystic ovarian syndrome: A systematic review and meta-analysis

Hamsho, M., Ranneh, Y., & Fadel, A. (2025) · Endocrinología Diabetes y Nutrición · doi:10.1016/j.endinu.2025.501578

Chromium supplementation in women with polycystic ovary syndrome: Systematic review and meta‐analysis

Tang, X., Sun, Z., & Gong, L. (2017) · Journal of obstetrics and gynaecology research · doi:10.1111/jog.13462 · Cited by 27 · see citing works

The Effects of Supplementation with Chromium on Insulin Resistance Indices in Women with Polycystic Ovarian Syndrome: A Systematic Review and Meta-Analysis of Randomized Clinical Trials

Heshmati, J., Samani, R. O., Vesali, S., Maroufizadeh, S., Rezaeinejad, M., Razavi, M., & Sepidarkish, M. (2018) · Hormone and Metabolic Research · doi:10.1055/s-0044-101835 · Cited by 38 · see citing works

The Effect of Chromium Supplementation on Insulin Resistance and Ovarian/Menstrual Cyclicity in Women With Polycystic Ovary Syndrome

Lucidi, R. S., Thyer, A. C., Siler‐Khodr, T. M., Holden, A. E., Rs, S., & Brzyski, R. G. (2005) · Fertility and Sterility · doi:10.1016/j.fertnstert.2005.07.1117

Effects of chromium supplementation on insulin sensitivity and reproductive function in polycystic ovarian syndrome: A pilot study

Lydic, M. L., McNurlan, M. A., Komaroff, E., Mitchell, L., Bembo, S. A., & Gelato, M. C. (2003) · Fertility and Sterility · doi:10.1016/s0015-0282(03)01923-x · Cited by 4 · see citing works