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Cited by 608

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Innovative Interventional and Imaging Registries: Precision Medicine in Cerebrovascular Disorders

Open access
Liebeskind, David S.·2015·Interventional Neurology

Abstract

Background: Precision medicine in cerebrovascular disorders may be greatly advanced by the use of innovative interventional and imaging-intensive registries. Registries have remained subsidiary to randomized controlled trials, yet vast opportunities exist to leverage big data in stroke. Summary: This overview builds upon the rationale for innovative, imaging-intensive interventional registries as a pivotal step in realizing precision medicine for several cerebrovascular disorders. Such enhanced registries may serve as a model for expansion of our translational research pipeline to fully leverage the role of phase IV investigations. The scope and role of registries in precision medicine are considered, followed by a review on the history of stroke and interventional registries, data considerations, critiques or barriers to such initiatives, and the potential modernization of registry methods into efficient, searchable, imaging-intensive resources that simultaneously offer clinical, research and educational added value. Key Messages: Recent advances in technology, informatics and endovascular stroke therapies converge to provide an exceptional opportunity for registries to catapult further progress. There is now a tremendous opportunity to deploy registries in acute stroke, intracranial atherosclerotic disease and carotid disease where other clinical trials leave questions unanswered. Unlike prior registries, imaging-intensive and modernized methods may leverage current technological capabilities around the world to efficiently address key objectives and provide added clinical, research and educational value.

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Metadata

Authors
Liebeskind, D. S.
Venue
Interventional Neurology
Publisher
S. Karger AG
Published
2015
Volume
4
Issue
1-2
Pages
5-17
ISSN
  • 1664-5545 (ISSN-L)
  • 1664-9737
OpenAlex
W2239752862
Cited by
608
References
24
FWCI
48.16
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Innovative Interventional and Imaging Registries: Precision Medicine in Cerebrovascular Disorders. https://app.cochat.ai/papers/10.1159/000438773
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Liebeskind, D. S. (2015). Innovative Interventional and Imaging Registries: Precision Medicine in Cerebrovascular Disorders. Interventional Neurology. https://doi.org/10.1159/000438773

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.