The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Influence of the HDL Receptor SR-BI on Lipoprotein Metabolism and Atherosclerosis
Open accessAbstract
The scavenger receptor class B type I (SR-BI) was the first molecularly well-defined cell-surface HDL receptor to be described. SR-BI mediates selective HDL cholesterol uptake by formation of a productive lipoprotein/receptor complex, which requires specific structural domains and conformation states of apolipoprotein A-I present in HDL particles. SR-BI is abundantly expressed in several tissues, including the liver, where its expression is regulated by various mechanisms, including the transcriptional activity of nuclear receptors. The importance of SR-BI in overall HDL cholesterol metabolism and its antiatherogenic activity in vivo has been definitively established by SR-BI gene manipulation in mice. Remarkably, SR-BI/apolipoprotein E double-knockout mice develop complex coronary artery disease, myocardial infarction, and heart failure. Additional studies should help to define the importance of SR-BI in human health and disease.
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Cites
Wang, L., Connelly, M. A., Ostermeyer, A. G., Chen, H.-H., Williams, D. L., & Brown, D. A. (2003) · Journal of Lipid Research · doi:10.1194/jlr.m200449-jlr200 · Cited by 59
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Bile acid signaling in metabolic disease and drug therapy
Li, T., & Chiang, J. Y. L. (2014) · Pharmacological Reviews · doi:10.1124/pr.113.008201 · Cited by 935
HDL, ABC transporters, and cholesterol efflux: implications for the treatment of atherosclerosis
Tall, A. R., Yvan-Charvet, L., Terasaka, N., Pagler, T., & Wang, N. (2008) · Cell Metabolism · doi:10.1016/j.cmet.2008.03.001 · Cited by 540
Atherosclerosis in the Apolipoprotein E–Deficient Mouse: A Decade of Progress
Meir, K. S., & Leitersdorf, E. (2004) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.0000128849.12617.f4 · Cited by 498
van der Steeg, W. A., Holme, I., Boekholdt, S. M., Larsen, M. L., Lindahl, C., Stroes, E. S. G., Tikkanen, M. J., Wareham, N. J., Faergeman, O., Olsson, A. G., et al. (2008) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2007.09.060 · Cited by 374
Genetic Variant of the Scavenger Receptor BI in Humans
Vergeer, M., Korporaal, S. J. A., Franssen, R., Meurs, I., Out, R., Hovingh, G. K., Hoekstra, M., Sierts, J. A., Dallinga-Thie, G. M., Motazacker, M. M., et al. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa0907687 · Cited by 317
Metadata
- Authors
- Trigatti, B. L., Krieger, M., & Rigotti, A.
- Venue
- Arteriosclerosis, Thrombosis, and Vascular Biology
- Published
- 2003-10
- Volume
- 23
- Issue
- 10
- Pages
- 1732-1738
- ISSN
- 1079-5642 (ISSN-L)
- 1524-4636
- OpenAlex
- W2121139264
- Cited by
- 257
- References
- 1
- FWCI
- 16.92
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Trigatti, B. L., Krieger, M., & Rigotti, A. (2003). Influence of the HDL Receptor SR-BI on Lipoprotein Metabolism and Atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. https://doi.org/10.1161/01.atv.0000091363.28501.84
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