Genetic Variant of the Scavenger Receptor BI in Humans

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Cholesteryl Ester Transfer Protein

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Molecular basis of lipid transfer protein deficiency in a family with increased high-density lipoproteins

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The Role of the High-Density Lipoprotein Receptor SR-BI in the Lipid Metabolism of Endocrine and Other Tissues

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Hepatic expression of scavenger receptor class B type I (SR-BI) is a positive regulator of macrophage reverse cholesterol transport in vivo

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Familial Deficiency of Apolipoproteins A-I and C-III and Precocious Coronary-Artery Disease

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Clinical use of unbound plasma cortisol as calculated from total cortisol and corticosteroid-binding globulin

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Familial Plasma Lecithin: Cholesterol Acyltransferase Deficiency Biochemical Study of a New Inborn Error of Metabolism

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Influence of the HDL Receptor SR-BI on Lipoprotein Metabolism and Atherosclerosis

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Differential Effects of Scavenger Receptor BI Deficiency on Lipid Metabolism in Cells of the Arterial Wall and in the Liver

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Scavenger Receptor Class B Type I–Mediated Protection Against Atherosclerosis in LDL Receptor–Negative Mice Involves Its Expression in Bone Marrow–Derived Cells

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Discovery of chemical inhibitors of the selective transfer of lipids mediated by the HDL receptor SR-BI

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Association of Polymorphisms at the SR-BI Gene Locus With Plasma Lipid Levels and Body Mass Index in a White Population

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Dual Role for Scavenger Receptor Class B, Type I on Bone Marrow-Derived Cells in Atherosclerotic Lesion Development

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SR-BI protects against endotoxemia in mice through its roles in glucocorticoid production and hepatic clearance

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Is raising HDL a futile strategy for atheroprotection?

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Scavenger receptor class B type I is solely responsible for the selective uptake of cholesteryl esters from HDL by the liver and the adrenals in mice

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Demethylation, Reactivation, and Destabilization of Human Fragile X Full-Mutation Alleles in Mouse Embryocarcinoma Cells

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Familial Plasma Lecithin:Cholesterol Acyltransferase Deficiency

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Relative Contributions of ABCA1 and SR-BI to Cholesterol Efflux to Serum From Fibroblasts and Macrophages

Duong, M., Collins, H. L., Jin, W., Zanotti, I., Favari, E., & Rothblat, G. H. (2006) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000203515.25574.19 · Cited by 105 · see citing works

Absence of HDL cholesteryl ester uptake in mice via SR-BI impairs an adequate adrenal glucocorticoid-mediated stress response to fasting

Hoekstra, M., Meurs, I., Koenders, M. M. J. F., Out, R., Hildebrand, R. B., Kruijt, J. K., Eck, M. V., & van Berkel, T. J. C. (2008) · Journal of Lipid Research · doi:10.1194/jlr.m700475-jlr200 · Cited by 91 · see citing works

Increased HDL Cholesterol and ApoA-I in Humans and Mice Treated With a Novel SR-BI Inhibitor

Masson, D., Koseki, M., Ishibashi, M., Larson, C. J., Miller, S. G., King, B. D., & Tall, A. R. (2009) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.109.191320 · Cited by 82 · see citing works

Thrombocytopenia and Platelet Abnormalities in High-Density Lipoprotein Receptor–Deficient Mice

Dole, V. S., Matuskova, J., Vasile, E., Yesilaltay, A., Bergmeier, W., Bernimoulin, M. P., Wagner, D. D., & Krieger, M. (2008) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.108.162347 · Cited by 82 · see citing works

Expression of Human Scavenger Receptor B1 on and in Human Platelets

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Scavenger Receptor Class B Type I Protein as an Independent Predictor of High-Density Lipoprotein Cholesterol Levels in Subjects with Hyperalphalipoproteinemia

West, M., Greason, E., Kolmakova, A., Jahangiri, A., Asztalos, B. F., Pollin, T. I., & Rodríguez, A. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-1223 · Cited by 75 · see citing works

Association Between a Novel 11–Base Pair Deletion Mutation in the Promoter Region of the Scavenger Receptor Class B Type I Gene and Plasma HDL Cholesterol Levels in Taiwanese Chinese

Hsu, L., Ko, Y., Wu, S., Teng, M., Peng, T.-Y., Chen, C.-F., Chen, C.-F., & Lee, Y. (2003) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000082525.84814.a9 · Cited by 62 · see citing works

Adrenal cortical function in homozygous familial hypercholesterolemia

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15-Lipoxygenase-mediated modification of high-density lipoproteins impairs SR-BI- and ABCA1-dependent cholesterol efflux from macrophages

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Adrenocortical Response to Adrenocorticotropin in Heterozygous Familial Hypercholesterolemia*

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Lecithin: Cholesterol Acyltransferase and Atherosclerosis

Rader, D. J. (2009) · Circulation · doi:10.1161/circulationaha.109.881979 · Cited by 22 · see citing works

Time to rethink high-density lipoprotein?

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Cholesterol Efflux and Atheroprotection: Advancing the Concept of Reverse Cholesterol Transport

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Bile acid signaling in metabolic disease and drug therapy

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Foam cells in atherosclerosis

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Early steps in steroidogenesis: intracellular cholesterol trafficking

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Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease

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Molecular Biology of Atherosclerosis

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SR-B1: A Unique Multifunctional Receptor for Cholesterol Influx and Efflux

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High-density lipoproteins: A consensus statement from the National Lipid Association

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HDL cholesterol: reappraisal of its clinical relevance

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Platelets in atherosclerosis

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Targeting Foam Cell Formation in Atherosclerosis: Therapeutic Potential of Natural Products

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Lipoprotein receptor signalling in atherosclerosis

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Molecular mechanisms of vascular effects of High‐density lipoprotein: alterations in cardiovascular disease

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SR-BI: A Multifunctional Receptor in Cholesterol Homeostasis and Atherosclerosis

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Regulation of cholesterol homeostasis

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Metabolic and functional relevance of HDL subspecies

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Emerging role of high density lipoproteins as a player in the immune system

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High-density lipoprotein as a modulator of platelet and coagulation responses

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Lecithin:cholesterol acyltransferase: old friend or foe in atherosclerosis?

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HDL Function and Atherosclerosis: Reactive Dicarbonyls as Promising Targets of Therapy

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Thematic Review Series: Lipid Transfer Proteins Scavenger receptor B type 1: expression, molecular regulation, and cholesterol transport function

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HDL and atherosclerotic cardiovascular disease: genetic insights into complex biology

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The Role of Maternal-Fetal Cholesterol Transport in Early Fetal Life: Current Insights1

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Mouse models of atherosclerosis and their suitability for the study of myocardial infarction

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Autoimmune Addison disease: pathophysiology and genetic complexity

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HDL Biogenesis, Remodeling, and Catabolism

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High Density Lipoprotein Cholesterol Efflux Capacity and Atherosclerosis in Cardiovascular Disease: Pathophysiological Aspects and Pharmacological Perspectives

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HDL endocytosis and resecretion

Röhrl, C., & Stangl, H. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2013.07.014 · Cited by 100 · see citing works

Understanding high-density lipoprotein function in disease: Recent advances in proteomics unravel the complexity of its composition and biology

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Scavenger Receptor class B type I (SR-BI): A versatile receptor with multiple functions and actions

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Intestinal CD36 and Other Key Proteins of Lipid Utilization: Role in Absorption and Gut Homeostasis

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Endocytosis of lipoproteins

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Reverse Cholesterol Transport Revisited

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HDL Cholesterol Metabolism and the Risk of CHD: New Insights from Human Genetics

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HDL functionality in reverse cholesterol transport — Challenges in translating data emerging from mouse models to human disease

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The Postbinding Activity of Scavenger Receptor Class B Type I Mediates Initiation of Hepatitis C Virus Infection and Viral Dissemination

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Atheroprotective Reverse Cholesterol Transport Pathway Is Defective in Familial Hypercholesterolemia

Bellanger, N., Orsoni, A., Julia, Z., Fournier, N., Frisdal, É., Duchêne, E., Bruckert, É., Carrié, A., Bonnefont‐Rousselot, D., Pirault, J., et al. (2011) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.111.227181 · Cited by 84 · see citing works

The HDL receptor SR-BI is associated with human prostate cancer progression and plays a possible role in establishing androgen independence

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Hunting human disease genes: lessons from the past, challenges for the future

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Proteomic Plasma Membrane Profiling Reveals an Essential Role for gp96 in the Cell Surface Expression of LDLR Family Members, Including the LDL Receptor and LRP6

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HDL, Atherosclerosis, and Emerging Therapies

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Anti-citrullinated protein antibodies contribute to platelet activation in rheumatoid arthritis

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High-Density Lipoproteins and the Immune System

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A New Frontier in Immunometabolism. Cholesterol in Lung Health and Disease

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Association of Serum Cholesterol Efflux Capacity With Mortality in Patients With ST-Segment Elevation Myocardial Infarction

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Novel mutations in scavenger receptor BI associated with high HDL cholesterol in humans

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Deficiency of Scavenger Receptor BI Leads to Impaired Lymphocyte Homeostasis and Autoimmune Disorders in Mice

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Macrophage SR-BI modulates autophagy via VPS34 complex and PPARα transcription of Tfeb in atherosclerosis

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Novel Pathways of Apolipoprotein A-I Metabolism in High-Density Lipoprotein of Different Sizes in Humans

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Rare SCARB1 mutations associate with high-density lipoprotein cholesterol but not with coronary artery disease

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Functions of scavenger receptor class B, type I in atherosclerosis

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Lipidomic Profiling of Liver Tissue from Obesity-Prone and Obesity-Resistant Mice Fed a High Fat Diet

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Platelet Function in Health and Disease: from Molecular Mechanisms, Redox Considerations to Novel Therapeutic Opportunities

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Emerging therapies for raising high-density lipoprotein cholesterol (HDL-C) and augmenting HDL particle functionality

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Mechanisms regulating hepatic SR-BI expression and their impact on HDL metabolism

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SR-BI as target in atherosclerosis and cardiovascular disease - A comprehensive appraisal of the cellular functions of SR-BI in physiology and disease

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HDL cholesterol concentrations and risk of atherosclerotic cardiovascular disease – Insights from randomized clinical trials and human genetics

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Glycine Dimerization Motif in the N-terminal Transmembrane Domain of the High Density Lipoprotein Receptor SR-BI Required for Normal Receptor Oligomerization and Lipid Transport

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Regulation of High-Density Lipoprotein on Hematopoietic Stem/Progenitor Cells in Atherosclerosis Requires Scavenger Receptor Type BI Expression

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Evidence of a Polygenic Origin of Extreme High-Density Lipoprotein Cholesterol Levels

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Multiple Sclerosis is Not a Disease of the Immune System

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Exoplasmic cysteine Cys384 of the HDL receptor SR-BI is critical for its sensitivity to a small-molecule inhibitor and normal lipid transport activity

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The effect of hepatic lipase on coronary artery disease in humans is influenced by the underlying lipoprotein phenotype

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Relationship between serum cholesterol and indices of erythrocytes and platelets in the US population

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High density lipoprotein as a source of cholesterol for adrenal steroidogenesis: a study in individuals with low plasma HDL-C

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Human genetics of HDL: Insight into particle metabolism and function

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Quercetin induces the selective uptake of HDL-cholesterol via promoting SR-BI expression and the activation of the PPARγ/LXRα pathway

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High-density lipoprotein subfractions: current views and clinical practice applications

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High-density lipoproteins (HDL): Novel function and therapeutic applications

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Hepatic Scavenger Receptor BI Protects Against Polymicrobial-induced Sepsis through Promoting LPS Clearance in Mice

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Functional Characterization of Newly-Discovered Mutations in Human SR-BI

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Cholesteryl Ester Transfer Protein Expression Partially Attenuates the Adverse Effects of SR-BI Receptor Deficiency on Cholesterol Metabolism and Atherosclerosis

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Apolipoprotein A-II is a key regulatory factor of HDL metabolism as appears from studies with transgenic animals and clinical outcomes

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Mendelian Disorders of High-Density Lipoprotein Metabolism

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A new role for the P2X7 receptor: a scavenger receptor for bacteria and apoptotic cells in the absence of serum and extracellular ATP

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Hypocholesterolemia, foam cell accumulation, but no atherosclerosis in mice lacking ABC-transporter A1 and scavenger receptor BI

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Adrenal-Specific Scavenger Receptor BI Deficiency Induces Glucocorticoid Insufficiency and Lowers Plasma Very-Low-Density and Low-Density Lipoprotein Levels in Mice

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The hepatic WASH complex is required for efficient plasma LDL and HDL cholesterol clearance

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Functionality of postprandial larger HDL2 particles is enhanced following CETP inhibition therapy

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SCARB1 Gene Variants Are Associated With the Phenotype of Combined High High-Density Lipoprotein Cholesterol and High Lipoprotein (a)

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Lysosome-Independent Intracellular Drug/Gene Codelivery by Lipoprotein-Derived Nanovector for Synergistic Apoptosis-Inducing Cancer-Targeted Therapy

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SR-B1’s Next Top Model: Structural Perspectives on the Functions of the HDL Receptor

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Cardiac and skeletal muscles show molecularly distinct responses to cancer cachexia

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Adrenocortical Scavenger Receptor Class B Type I Deficiency Exacerbates Endotoxic Shock and Precipitates Sepsis-Induced Mortality in Mice

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Implications of reverse cholesterol transport: Recent studies

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Cholesteryl ester transfer protein: An enigmatic pharmacology – Antagonists and agonists

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Familial hypercholesterolaemia: cholesterol efflux and coronary disease

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Functional validation of new pathways in lipoprotein metabolism identified by human genetics

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New developments in selective cholesteryl ester uptake

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An In-Silico Model of Lipoprotein Metabolism and Kinetics for the Evaluation of Targets and Biomarkers in the Reverse Cholesterol Transport Pathway

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Novel concepts in HDL pharmacology.

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Aerobic exercise training enhances the in vivo cholesterol trafficking from macrophages to the liver independently of changes in the expression of genes involved in lipid flux in macrophages and aorta

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Shotgun proteomic analysis reveals proteome alterations in HDL of patients with cholesteryl ester transfer protein deficiency

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Genomic Variants and Multilevel Regulation of ABCA1, ABCG1, and SCARB1 Expression in Atherogenesis

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Developmental abnormalities in mouse embryos lacking the HDL receptor SR-BI

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Functional genomics of the human high-density lipoprotein receptor scavenger receptor BI

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Novel mutations in scavenger receptor BI associated with high HDL cholesterol in humans

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Abstract 126: Identification of an Individual With Extremely High HDL-C Who is Homozygous for a Loss-of-function Mutation in Scavenger Receptor BI (SR-BI) and Functional Characterization of the Mutation

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Genetic studies in mice and humans reveal new physiological roles for the high-density lipoprotein receptor scavenger receptor class B type I

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Genetic variants of the scavenger receptor class B type I and influences on human HDL metabolism

Winter, K. S. (2013) · University of Vienna · doi:10.25365/thesis.26236