The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
The Mystery of PCSK9
Abstract
any of the most important breakthroughs in science do not come from hypothesis-driven experiments.Apart from serendipity, genetics is perhaps our best route to discoveries that elude our intuition.Genetics establishes a relationship between a gene and a phenotype, but does not necessarily provide mechanistic information.The emerging story of PCSK9 (originally called Narc-1) provides a case in point.
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Claims the paper makes
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Each is checked against this paper’s own text: does it say what the citing paper says it does?
PCSK9 is a proprotein convertase of the subtilisin (S8) family of serine proteases.
“PCSK9 (proprotein convertase subtilisin kexin type 9), also known as neural-apoptosis-regulated convertase 1, is a prohormoneproprotein convertase of the subtilisin (S8) family of serine proteases (Attie, 2004;Maxwell & Breslow, 2005).”
From PCSK9 is required for the disposal of non-acetylated intermediates of the nascent membrane protein BACE1 (2008) · cites this paper as Attie, 2004
Citations
Cites
Michaely, P., Li, W.-P., Anderson, R. G. W., Cohen, J. C., & Hobbs, H. H. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m405242200 · Cited by 66
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Research works printed but not linked: 30
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Cited by
Sorted by citations
Jonas, M. C., Costantini, C., & Puglielli, L. (2008) · The EMBO Reports · doi:10.1038/embor.2008.132 · Cited by 119
Lalanne, F., Lambert, G., Amar, M. J. A., Chétiveaux, M., Zaïr, Y., Jarnoux, A.-L., Ouguerram, K., Friburg, J., Seidah, N. G., Brewer, H. B., et al. (2005) · Journal of Lipid Research · doi:10.1194/jlr.m400396-jlr200 · Cited by 104
Metadata
- Authors
- Attie, A. D.
- Venue
- Arteriosclerosis, Thrombosis, and Vascular Biology
- Published
- 2004-08
- Volume
- 24
- Issue
- 8
- Pages
- 1337-1339
- ISSN
- 1079-5642
- 1524-4636
- Cited by
- 16
- References
- 1
- Language
- en
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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