Cited by 103Cholesterol and Lipid MetabolismAtherosclerosis and Cardiovascular DiseasesLipoproteins and Cardiovascular Health

The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.

Arterial Permeability and Efflux of Apolipoprotein B–Containing Lipoproteins Assessed by In Situ Perfusion and Three-Dimensional Quantitative Confocal Microscopy

Open access

Proctor, Spencer D., Vine, Donna F., Mamo, John C.L.·2004·Arteriosclerosis, Thrombosis, and Vascular Biology

DOI 10.1161/01.atv.0000143859.75035.5a

Open this paper in CoChat — free account Open PDF

Abstract

Objectives— There is accumulating evidence that an increased risk of cardiovascular disease (CVD) is not simply caused by the degree of arterial exposure to plasma lipoproteins but, in addition, is determined by the affinity of the vasculature for different lipoprotein phenotypes. In this study we compare the delivery and efflux of 2 atherogenic lipoproteins to further understand the factors that regulate cholesterol accumulation in early atherogenesis. Methods and Results— Lipoproteins containing apolipoprotein (apo) B100 (a low-density lipoprotein [LDL]) and apoB48 (chylomicron remnants) were isolated and differentially conjugated with fluorophores and simultaneously perfused at equivalent concentrations in situ through rabbit carotid vessels. Perfusion systems were established to quantify and differentiate between lipoprotein arterial delivery and efflux. The total average rate of delivery for LDL particles (23 nm) compared with chylomicron remnants (50 nm) was 4427 particles/min −1 per μm 3 and 452 particles/min −1 per μm 3 , respectively. In contrast, the average rate of efflux was 3195 particles/min −1 per μm 3 and 163 particles/min −1 per μm 3 for LDL and chylomicron remnants, respectively. Conclusions— Results indicate that although LDL particles have a higher rate of delivery, they efflux more readily from arterial tissue compared with the larger chylomicron remnants. Collectively, our findings highlight that lipoproteins permeate through arterial tissue differently and may be dependent on the phenotype and potential interactions with extracellular matrix components.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1161/01.atv.0000143859.75035.5a

Cites

30 of 30 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

THE DISTRIBUTION AND CHEMICAL COMPOSITION OF ULTRACENTRIFUGALLY SEPARATED LIPOPROTEINS IN HUMAN SERUM
Havel, R. J., Eder, H. A., & Bragdon, J. H. (1955) · Journal of Clinical Investigation · doi:10.1172/jci103182 · Cited by 8,737
Atherogenesis: a postprandial phenomenon.
Zilversmit, D. B. (1979) · Circulation · doi:10.1161/01.cir.60.3.473 · Cited by 1,701
Subendothelial retention of atherogenic lipoproteins in early atherosclerosis
Skålén, K., Gustafsson, M., Rydberg, E. K., Hultén, L. M., Wiklund, O., Innerarity, T. L., & Borén, J. (2002) · Nature · doi:10.1038/nature00804 · Cited by 1,019
Initiation of atherosclerotic lesions in cholesterol-fed rabbits. II. Selective retention of LDL vs. selective increases in LDL permeability in susceptible sites of arteries.
Schwenke, D. C., & Carew, T. E. (1989) · Arteriosclerosis An Official Journal of the American Heart Association Inc · doi:10.1161/01.atv.9.6.908 · Cited by 344
Selective Retention of VLDL, IDL, and LDL in the Arterial Intima of Genetically Hyperlipidemic Rabbits In Vivo: Molecular Size as a Determinant of Fractional Loss From the Intima–Inner Media
Nordestgaard, B. G., Wootton, R., & Lewis, B. (1995) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.15.4.534 · Cited by 334
Comparison of Apolipoprotein and Proteoglycan Deposits in Human Coronary Atherosclerotic Plaques
O’Brien, K. D., Olin, K. L., Alpers, C. E., Chiu, W. S., Ferguson, M. S., Hudkins, K. L., Wight, T. N., & Chait, A. (1998) · Circulation · doi:10.1161/01.cir.98.6.519 · Cited by 271
Clinical relevance of the biochemical, metabolic, and genetic factors that influence low-density lipoprotein heterogeneity
Kwiterovich, P. O. (2002) · The American Journal of Cardiology · doi:10.1016/s0002-9149(02)02749-2 · Cited by 208
Arterial retention of apolipoprotein B48- and B100-containing lipoproteins in atherogenesis
Proctor, S. D., Vine, D. F., & Mamo, J. C. L. (2002) · Current Opinion in Lipidology · doi:10.1097/00041433-200210000-00001 · Cited by 200
Self-citation
Cellular Consequences of the Association of ApoB Lipoproteins With Proteoglycans
Hurt‐Camejo, E., Olsson, U., Wiklund, O., Bondjers, G., & Camejo, G. (1997) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.17.6.1011 · Cited by 165
Retention of fluorescent‐labelled chylomicron remnants within the intima of the arterial wall — evidence that plaque cholesterol may be derived from post‐prandial lipoproteins
Proctor, S. D., & Mamo, J. C. L. (1998) · European Journal of Clinical Investigation · doi:10.1046/j.1365-2362.1998.00317.x · Cited by 147
Self-citation

Show all 30 references

Research works printed but not linked: 9

1996, Coron Artery Dis, 7, 239
10.1161/circ.60.3.222498 · DOI
10.1161/atvb.22.2.211 · DOI
2002, Life Science, 14, 30
1991, Targeted Diagn Ther, 5, 45
10.1161/atvb.15.4.534 · DOI
10.1161/atvb.17.6.1011 · DOI
10.1161/circ.98.6.519 · DOI
10.1161/atvb.21.1.129 · DOI

Sorted by citations

Dyslipidemia in obesity: Mechanisms and potential targets
Klop, B., Elte, J., & Cabezas, M. (2013) · Nutrients · doi:10.3390/nu5041218 · Cited by 1,665
“This process takes place at the liver and acts as an anti-atherogenic mechanism, but it may also take place in other tissues where cholesterol can not be removed efficiently leading to cholesterol accumulation and therefore the initiation of the atherosclerotic plaque [56,57,61,62].”
Background
Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies—a consensus statement from the European Atherosclerosis Society
Ginsberg, H. N., Packard, C. J., Chapman, M. J., Borén, J., Aguilar-Salinas, C. A., Averna, M., Ference, B. A., Gaudet, D., Hegele, R. A., Kersten, S., et al. (2021) · European Heart Journal · doi:10.1093/eurheartj/ehab551 · Cited by 979
Dyslipidemia and cardiovascular disease risk among the MASHAD study population
Hedayatnia, M., Asadi, Z., Zare‐Feyzabadi, R., Yaghooti‐Khorasani, M., Ghazizadeh, H., Zirak, R. G., Tirkani, A. N., Mohammadi‐Bajgiran, M., Rohban, M., Sadabadi, F., et al. (2020) · Lipids in Health and Disease · doi:10.1186/s12944-020-01204-y · Cited by 406
Alternate day fasting and endurance exercise combine to reduce body weight and favorably alter plasma lipids in obese humans
Bhutani, S., Klempel, M. C., Kroeger, C. M., Trepanowski, J. F., & Varady, K. A. (2013) · Obesity · doi:10.1002/oby.20353 · Cited by 349
Rationale and design of the Pemafibrate to Reduce Cardiovascular Outcomes by Reducing Triglycerides in Patients with Diabetes (PROMINENT) study
Pradhan, A. D., Paynter, N. P., Everett, B. M., Glynn, R. J., Amarenco, P., Elam, M., Ginsberg, H., Hiatt, W. R., Ishibashi, S., Koenig, W., et al. (2018) · American Heart Journal · doi:10.1016/j.ahj.2018.09.011 · Cited by 319
Small animal models of cardiovascular disease: tools for the study of the roles of metabolic syndrome, dyslipidemia, and atherosclerosis
Russell, J. C., & Proctor, S. D. (2006) · Cardiovascular Pathology · doi:10.1016/j.carpath.2006.09.001 · Cited by 317
Self-citation
Postprandial lipemia and cardiovascular disease risk: interrelationships between dietary, physiological and genetic determinants
Jackson, K. G., Poppitt, S. D., & Minihane, A. M. (2012) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2011.08.012 · Cited by 246
Exenatide suppresses postprandial elevations in lipids and lipoproteins in individuals with impaired glucose tolerance and recent onset type 2 diabetes mellitus
Schwartz, E. A., Koska, J., Mullin, M. P., Syoufi, I., Schwenke, D. C., & Reaven, P. D. (2010) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2010.05.028 · Cited by 173
Postprandial lipoproteins and the molecular regulation of vascular homeostasis
Botham, K. M., & Wheeler-Jones, C. P. D. (2013) · Progress in Lipid Research · doi:10.1016/j.plipres.2013.06.001 · Cited by 137
Role of Omega-3 Fatty Acids in Cardiovascular Disease: the Debate Continues
Sherratt, S. C. R., Libby, P., Budoff, M. J., Bhatt, D. L., & Mason, R. P. (2022) · Current Atherosclerosis Reports · doi:10.1007/s11883-022-01075-x · Cited by 156
Lipolysis of triglyceride-rich lipoproteins, vascular inflammation, and atherosclerosis
Schwartz, E. A., & Reaven, P. D. (2012) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2011.09.021 · Cited by 130
Comparison of effects of diet versus exercise weight loss regimens on LDL and HDL particle size in obese adults
Varady, K. A., Bhutani, S., Klempel, M. C., & Kroeger, C. M. (2011) · Lipids in Health and Disease · doi:10.1186/1476-511x-10-119 · Cited by 116
Postprandial hyperlipidemia, endothelial dysfunction and cardiovascular risk: focus on incretins
Ansar, S., Koška, J., & Reaven, P. D. (2011) · Cardiovascular Diabetology · doi:10.1186/1475-2840-10-61 · Cited by 115
Triglyceride-Rich Lipoprotein Remnants and Cardiovascular Disease
Duran, E. K., & Pradhan, A. D. (2020) · Clinical Chemistry · doi:10.1093/clinchem/hvaa296 · Cited by 108
Understanding Postprandial Inflammation and Its Relationship to Lifestyle Behaviour and Metabolic Diseases
Klop, B., Proctor, S. D., Mamo, J. C. L., Botham, K. M., & Cabezas, M. C. (2011) · International Journal of Vascular Medicine · doi:10.1155/2012/947417 · Cited by 96
Self-citation
Sphingomyelinase Induces Aggregation and Fusion of Small Very Low–Density Lipoprotein and Intermediate-Density Lipoprotein Particles and Increases Their Retention to Human Arterial Proteoglycans
Öörni, K., Posio, P., Ala‐Korpela, M., Jauhiainen, M., & Kovanen, P. T. (2005) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000168912.42941.60 · Cited by 93
Impaired postprandial apolipoprotein-B48 metabolism in the obese, insulin-resistant JCR:LA-cp rat: Increased atherogenicity for the metabolic syndrome
Vine, D. F., Takechi, R., Russell, J. C., & Proctor, S. D. (2006) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2006.03.013 · Cited by 88
Self-citation
Triglycerides and cardiovascular disease
Esan, O., & Wierzbicki, A. S. (2021) · Current Opinion in Cardiology · doi:10.1097/hco.0000000000000862 · Cited by 87
Transendothelial transport of lipoproteins
Jang, E., Robert, J., Rohrer, L., von Eckardstein, A., & Lee, W. L. (2020) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2020.09.020 · Cited by 85
Regulation of chylomicron production in humans
Xiao, C., & Lewis, G. F. (2011) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2011.09.019 · Cited by 80
Quantification of glucose diffusion in arterial tissues by using optical coherence tomography
Larin, K. V., Ghosn, M. G., Ivers, S. N., Téllez, A., & Granada, J. F. (2006) · Laser Physics Letters · doi:10.1002/lapl.200610111 · Cited by 73
Modification of lipoprotein metabolism and function driving atherogenesis in diabetes
Luciani, L., Pedrelli, M., & Parini, P. (2024) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2024.117545 · Cited by 72
Pathophysiology of hypertriglyceridemia
Hassing, H. C., Surendran, R. P., Mooij, H. L., Stroes, E. S. G., Nieuwdorp, M., & Dallinga‐Thie, G. M. (2011) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2011.11.010 · Cited by 71
Dietary supplementation of n‐3 PUFA reduces weight gain and improves postprandial lipaemia and the associated inflammatory response in the obese JCR:LA‐cp rat
Hassanali, Z., Ametaj, B. N., Field, C. J., Proctor, S. D., & Vine, D. F. (2009) · Diabetes Obesity and Metabolism · doi:10.1111/j.1463-1326.2009.01130.x · Cited by 72
Self-citation
The postprandial actions of GLP-1 receptor agonists: The missing link for cardiovascular and kidney protection in type 2 diabetes
Thomas, M. C., Coughlan, M. T., & Cooper, M. E. (2023) · Cell Metabolism · doi:10.1016/j.cmet.2023.01.004 · Cited by 63
Proteoglycan mediated lipoprotein retention: A mechanism of diabetic atherosclerosis
Tannock, L. R., & King, V. L. (2008) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-008-9078-0 · Cited by 57
Intestinal microsomal triglyceride transfer protein in type 2 diabetic and non-diabetic subjects: The relationship to triglyceride-rich postprandial lipoprotein composition
Phillips, C. M., Mullan, K., Owens, D., & TOMKIN, G. H. (2005) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2005.08.020 · Cited by 52
Remarkable increase of apolipoprotein B48 level in diabetic patients with end-stage renal disease
Hayashi, T., Hirano, T., Taira, T., Tokuno, A., Mori, Y., Koba, S., & Adachi, M. (2007) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2007.03.015 · Cited by 53
Inflammatory Links Between Hypertriglyceridemia and Atherogenesis
Peng, X., & Wu, H. (2022) · Current Atherosclerosis Reports · doi:10.1007/s11883-022-01006-w · Cited by 51
Postprandial Dyslipidemia: Pathophysiology and Cardiovascular Disease Risk Assessment.
Higgins, V., & Adeli, K. (2017) · PubMed Central · Cited by 47
Targeting the vasculature in cardiometabolic disease
Boutagy, N. E., Singh, A. K., & Sessa, W. C. (2022) · Journal of Clinical Investigation · doi:10.1172/jci148556 · Cited by 45
Chylomicron and apoB48 metabolism in the JCR:LA corpulent rat, a model for the metabolic syndrome
Mangat, R., Su, J. W., Scott, P. G., Russell, J. C., Vine, D. F., & Proctor, S. D. (2007) · Biochemical Society Transactions · doi:10.1042/bst0350477 · Cited by 39
Self-citation
Increased risk of cardiovascular disease in Type 1 diabetes: arterial exposure to remnant lipoproteins leads to enhanced deposition of cholesterol and binding to glycated extracellular matrix proteoglycans
Mangat, R., Su, J. W., Lambert, J. E., Clandinin, M. T., Wang, Y., Uwiera, R. R. E., Forbes, J. M., Vine, D. F., Cooper, M. E., Mamo, J. C. L., et al. (2010) · Diabetic Medicine · doi:10.1111/j.1464-5491.2010.03138.x · Cited by 39
Self-citation
The iterative lipid impact on inflammation in atherosclerosis
Kraaijenhof, J. M., Hovingh, G. K., Stroes, E. S. G., & Kroon, J. (2021) · Current Opinion in Lipidology · doi:10.1097/mol.0000000000000779 · Cited by 39
Elevated levels of platelet microparticles in carotid atherosclerosis and during the postprandial state
Michelsen, A. E., Notø, A. W., Brodin, E. E., Mathiesen, E. B., Brosstad, F. R., & Hansen, J. (2008) · Thrombosis Research · doi:10.1016/j.thromres.2008.10.016 · Cited by 41
Omega-3-fatty acids: Do they prevent cardiovascular disease?
Mason, R. P., Sherratt, S. C. R., & Eckel, R. H. (2022) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2022.101681 · Cited by 39
Atherogenic Lipoproteins for the Statin Residual Cardiovascular Disease Risk
Yanai, H., Adachi, H., Hakoshima, M., & Katsuyama, H. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232113499 · Cited by 40
Effect of metformin and flutamide on insulin, lipogenic and androgen-estrogen signaling, and cardiometabolic risk in a PCOS-prone metabolic syndrome rodent model
Kupreeva, M., Diané, A., Lehner, R. S., Watts, R., Ghosh, M., Proctor, S. D., & Vine, D. F. (2018) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00018.2018 · Cited by 34
Self-citation
Intestinal lipid transport and chylomicron production: Possible links to exacerbated atherogenesis in a rodent model of the metabolic syndrome
Vine, D. F., Glimm, D. R., & Proctor, S. D. (2008) · Atherosclerosis Supplements · doi:10.1016/j.atherosclerosissup.2008.05.004 · Cited by 34
Self-citation
Spatial Distributions of Lipids in Atherosclerosis of Human Coronary Arteries Studied by Time-of-Flight Secondary Ion Mass Spectrometry
Lehti, S., Sjövall, P., Käkelä, R., Mäyränpää, M. I., Kovanen, P. T., & Öörni, K. (2015) · American Journal Of Pathology · doi:10.1016/j.ajpath.2015.01.026 · Cited by 30
Degradation of the endothelial glycocalyx is associated with chylomicron leakage in mouse cremaster muscle microcirculation
Constantinescu, A. A., Spaan, J. A. E., Arkenbout, E. K., Vink, H., & VanTeeffelen, J. W. G. E. (2010) · Thrombosis and Haemostasis · doi:10.1160/th10-08-0560 · Cited by 29
Atherosclerosis: from lipid-lowering and anti-inflammatory therapies to targeting arterial retention of ApoB-containing lipoproteins
Araujo, G., Valencia, L. M., Martin-Ozimek, A., Soto, Y., & Proctor, S. D. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1485801 · Cited by 29
Self-citation
Triglyceride-Rich Lipoproteins as a Source of Proinflammatory Lipids in the Arterial Wall
Öörni, K., Lehti, S., Sjövall, P., & Kovanen, P. T. (2018) · Current Medicinal Chemistry · doi:10.2174/0929867325666180530094819 · Cited by 28
Arterial Retention of Remnant Lipoproteins Ex Vivo Is Increased in Insulin Resistance Because of Increased Arterial Biglycan and Production of Cholesterol‐Rich Atherogenic Particles That Can Be Improved by Ezetimibe in the JCR:LA‐ cp Rat
Mangat, R., Warnakula, S., Borthwick, F., Hassanali, Z., Uwiera, R. R. E., Russell, J. C., Cheeseman, C. I., Vine, D. F., & Proctor, S. D. (2012) · Journal of the American Heart Association · doi:10.1161/jaha.112.003434 · Cited by 26
Self-citation
Remnant cholesterol is more positively related to diabetes, prediabetes, and insulin resistance than conventional lipid parameters and lipid ratios: A multicenter, large sample survey
Li, B., Liu, Y., Zhou, X. J., Chen, L., Yan, L., Tang, X., Gao, Z., Wan, Q., Luo, Z., Qin, G., et al. (2024) · Journal of Diabetes · doi:10.1111/1753-0407.13592 · Cited by 27
Molecular Biological and Clinical Understanding of the Statin Residual Cardiovascular Disease Risk and Peroxisome Proliferator-Activated Receptor Alpha Agonists and Ezetimibe for Its Treatment
Yanai, H., Adachi, H., Hakoshima, M., & Katsuyama, H. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23073418 · Cited by 25
ApoA-1 infusion reduces arterial cholesterol and myocardial lesions in a rat model of cardiac dysfunction and insulin resistance
Borthwick, F., Warnakula, S., Mangat, R., Uwiera, R. R. E., Russell, J. C., Kelly, S. E., Lee, C. Y. W., Hryshko, L. V., Mamo, J. C. L., Rye, K., et al. (2012) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2012.03.006 · Cited by 24
Self-citation
The intestine as a regulator of cholesterol homeostasis in diabetes
TOMKIN, G. H. (2008) · Atherosclerosis Supplements · doi:10.1016/j.atherosclerosissup.2008.05.012 · Cited by 23
In vivo evidence for chylomicrons as mediators of postprandial inflammation
de Vries, M. A., Klop, B., Alipour, A., van de Geijn, G. M., Prinzen, L., Liem, A. H., Valdivielso, P., Rioja, J., Ramírez‐Bollero, J., & Cabezas, M. C. (2015) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2015.10.025 · Cited by 24
The Apolipoprotein C-I Content of Very-Low-Density Lipoproteins Is Associated with Fasting Triglycerides, Postprandial Lipemia, and Carotid Atherosclerosis
Hansen, J., Fernández, J. A., Notø, A. W., Deguchi, H., Björkegren, J., & Mathiesen, E. B. (2011) · Journal of Lipids · doi:10.1155/2011/271062 · Cited by 25
Postprandial Lipid Metabolism: The Missing Link Between Life-Style Habits and the Increasing Incidence of Metabolic Diseases in Western Countries?~!2009-09-30~!2010-01-26~!2010-03-30~!
Bravo, E., Napolitano, M., & Botham, K. M. (2010) · The Open Translational Medicine Journal · doi:10.2174/1876399501002010001 · Cited by 25
New Therapeutic Approaches to the Treatment of Dyslipidemia 1: ApoC-III and ANGPTL3
Kim, J. Y., & Kim, N. H. (2023) · Journal of Lipid and Atherosclerosis · doi:10.12997/jla.2023.12.1.23 · Cited by 23
Pair feeding-mediated changes in metabolism: stress response and pathophysiology in insulin-resistant, atherosclerosis-prone JCR:LA-cp rats
Russell, J. C., Proctor, S. D., Kelly, S. E., & Brindley, D. N. (2008) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.90257.2008 · Cited by 22
Self-citation
Acidity and lipolysis by group V secreted phospholipase A2 strongly increase the binding of apoB-100-containing lipoproteins to human aortic proteoglycans
Lähdesmäki, K., Öörni, K., Alanne-Kinnunen, M., Jauhiainen, M., Hurt‐Camejo, E., & Kovanen, P. T. (2011) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2011.10.014 · Cited by 22
Postprandial dyslipidemia in insulin resistant states in adolescent populations
Higgins, V., & Adeli, K. (2020) · Journal of Biomedical Research · doi:10.7555/jbr.34.20190094 · Cited by 20
The role of triglycerides in the origin and progression of atherosclerosis
Padró, T., Muñoz‐García, N., & Badimón, L. (2021) · Clínica e Investigación en Arteriosclerosis · doi:10.1016/j.arteri.2021.02.007 · Cited by 25
New Insights Into How the Intestine Can Regulate Lipid Homeostasis and Impact Vascular Disease: Frontiers for New Pharmaceutical Therapies to Lower Cardiovascular Disease Risk
Warnakula, S., Hsieh, J., Adeli, K., Hussain, M. M., Tso, P., & Proctor, S. D. (2011) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2010.12.020 · Cited by 19
Self-citation
Increased Apolipoprotein Deposits in Early Atherosclerotic Lesions Distinguish Symptomatic From Asymptomatic Patients
von Ballmoos, M. C. W., Dubler, D., Mirlacher, M., Cathomas, G., Muser, J., & Biedermann, B. C. (2005) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000198250.91406.6d · Cited by 19
Delayed clearance of triglyceride‐rich lipoproteins in young, healthy obese subjects
Larsen, M. A., Goll, R., Lekahl, S., Moen, O. S., & Florholmen, J. R. (2015) · Clinical Obesity · doi:10.1111/cob.12118 · Cited by 18
Rimonabant-mediated changes in intestinal lipid metabolism and improved renal vascular dysfunction in the JCR:LA-cprat model of prediabetic metabolic syndrome
Russell, J. C., Kelly, S. E., Diané, A., Wang, Y., Mangat, R., Novak, S., Vine, D. F., & Proctor, S. D. (2010) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00173.2010 · Cited by 17
Self-citation
SPPARM alpha: the Lazarus effect
Fruchart, J., & Santos, R. D. (2019) · Current Opinion in Lipidology · doi:10.1097/mol.0000000000000640 · Cited by 17
Irbesartan‐mediated reduction of renal and cardiac damage in insulin resistant JCR : LA‐cprats
Russell, J., Kelly, S., Vine, D. F., & Proctor, S. D. (2009) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2009.00417.x · Cited by 14
Self-citation
Role of Altered Metabolism of Triglyceride-Rich Lipoprotein Particles in the Development of Vascular Dysfunction in Systemic Lupus Erythematosus
Diószegi, Á., Lőrincz, H., Kaáli, E., Soltész, P., Perge, B., Varga, É., Harangi, M., & Tarr, T. (2023) · Biomolecules · doi:10.3390/biom13030401 · Cited by 13
Significant Increase of Apolipoprotein B48 Levels by a Standard Test Meal in Type 2 Diabetic Patients with Nephropathy
Yamamoto, T., Hirano, T., Mori, Y., Tokuno, A., Nagashima, M., Takada, M., Morita, R., Lee, S., Hayashi, T., & Adachi, M. (2008) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.e558 · Cited by 13
Lowering triglycerides to modify cardiovascular risk: will icosapent deliver?
Nicholls, S. J., & Scherer, D. J. (2015) · Vascular Health and Risk Management · doi:10.2147/vhrm.s40134 · Cited by 12
Elastic Fiber Fragmentation Increases Transmural Hydraulic Conductance and Solute Transport in Mouse Arteries
Cocciolone, A. J., Johnson, E. O., Shao, J., & Wagenseil, J. E. (2018) · Journal of Biomechanical Engineering · doi:10.1115/1.4042173 · Cited by 12
Increased Postprandial Triglyceride‐Rich Lipoprotein Levels in Elderly Survivors of Myocardial Infarction
Lekhal, S., Børvik, T., Nordøy, A., & Hansen, J. (2008) · Lipids · doi:10.1007/s11745-008-3165-6 · Cited by 12
Association between Intermediate-Density Lipoprotein Particles and the Progression of Carotid Atherosclerosis: A Community-Based Cohort Study
Liu, T., Zhao, D., Wang, M., Sun, J., Liu, J., Li, J., Duan, Y., Hu, P., Sun, Z., Liu, J., et al. (2023) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.63937 · Cited by 11
Model of intestinal chylomicron over-production and Ezetimibe treatment: Impact on the retention of cholesterol in arterial vessels
Mangat, R., Warnakula, S., Wang, Y., Russell, J. C., Uwiera, R. R. E., Vine, D. F., & Proctor, S. D. (2010) · Atherosclerosis Supplements · doi:10.1016/j.atherosclerosissup.2010.04.043 · Cited by 11
Self-citation
Dietary fat and physiological determinants of plasma chylomicron remnant homoeostasis in normolipidaemic subjects: insight into atherogenic risk
Irawati, D., Mamo, J. C. L., Clark, K., Soares, M. J., & James, A. P. (2017) · British Journal Of Nutrition · doi:10.1017/s0007114517000150 · Cited by 10
Self-citation
Atherogenic ApoB-dyslipidemia, atherosclerotic cardiovascular disease, cardiac dysfunction and remodeling in high-risk young women with and without polycystic ovary syndrome: A pilot study
Wu, X., Wilke, M., Batara, J., Proctor, S. D., Cree‐Green, M., Ghosh, M., Raggi, P., Windram, J. D., Becher, H. H., & Vine, D. F. (2025) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1520922 · Cited by 10
Self-citation
Delayed Metabolism of Postprandial Triglyceride‐Rich Lipoproteins in Subjects with Echolucent Carotid Plaques
Notø, A. W., Mathiesen, E. B., Brox, J. H., Björkegren, J., & Hansen, J. (2008) · Lipids · doi:10.1007/s11745-008-3159-4 · Cited by 9
Triglicéridos, colesterol HDL y dislipidemia aterogénica en la guía europea para el control de las dislipidemias 2019
Pedro‐Botet, J., Ascaso, J. F., Blasco, M., Brea, Á., Rodríguez, Á. D., Hernández‐Mijares, A., Pintó, X., & Millán, J. (2020) · Clínica e Investigación en Arteriosclerosis · doi:10.1016/j.arteri.2019.12.003 · Cited by 14
Predictive utility of remnant cholesterol in atherosclerotic cardiovascular disease
Proctor, S. D., Wang, M., Vine, D. F., & Raggi, P. (2024) · Current Opinion in Cardiology · doi:10.1097/hco.0000000000001140 · Cited by 9
Self-citation
Associations of intra‐pancreatic fat deposition with triglyceride‐rich lipoproteins and lipoprotein lipase
Liu, Y., Skudder‐Hill, L., Kimita, W., Shamaitijiang, X., Sequeira, I. R., & Petrov, M. S. (2025) · Diabetes Obesity and Metabolism · doi:10.1111/dom.16338 · Cited by 6
Thyroid Function Influences Serum Apolipoprotein B-48 Levels in Patients with Thyroid Disease
Mugii, S., Hanada, H., Okubo, M., Masuda, D., Takeoka, K., Hidaka, Y., Ohama, T., Matsuyama, A., Nakagawa-Toyama, Y., Nishida, M., et al. (2012) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.12757 · Cited by 6
Phospholipase A2 Mediates Apolipoprotein-Independent Uptake of Chylomicron Remnant-Like Particles by Human Macrophages
Napolitano, M., Kruth, H. S., & Bravo, E. (2011) · International Journal of Vascular Medicine · doi:10.1155/2012/501954 · Cited by 6
Transport across the thoracic aortic wall: implications for aneurysm pathobiology, diagnosis, and treatment
Kailash, K. A., Akanda, S. R., Davis, A. L., Crandall, C. L., Zaghloul, M. S., Setton, L. A., Halabi, C. M., Zayed, M. A., & Wagenseil, J. E. (2025) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00886.2024 · Cited by 5
Monoclonal Antibody chP3R99 Reduces Subendothelial Retention of Atherogenic Lipoproteins in Insulin‐Resistant Rats: Acute Treatment Versus Long‐Term Protection as an Idiotypic Vaccine for Atherosclerosis
Soto, Y., Hernández, A., Sarduy, R., Navarro, V. B., Marleau, S., Vine, D. F., Vázquez, A. M., & Proctor, S. D. (2024) · Journal of the American Heart Association · doi:10.1161/jaha.123.032419 · Cited by 5
Self-citation
Functional foods and coronary heart disease (CHD)
Lovegrove, J. A., & Jackson, K. G. (2011) · Elsevier eBooks · doi:10.1533/9780857092557.2.153 · Cited by 5
Roles of Achieved Levels of Low-Density Lipoprotein Cholesterol and High-Sensitivity C-Reactive Protein on Cardiovascular Outcome in Statin Therapy
Hyun, M. H., Lee, Y.-C., Choi, B. G., Na, J. O., Choi, C. U., Kim, J. W., Kim, E. J., Rha, S., Park, C. G., Lee, E. M., et al. (2019) · Cardiovascular Therapeutics · doi:10.1155/2019/3824823 · Cited by 6
Decreased lipoprotein lipase activity and increased postprandial concentrations of triglyceride-rich lipoproteins in offspring of elderly survivors of myocardial infarction
Lekhal, S., Børvik, T., Nordøy, A., & Hansen, J. (2008) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2007.10.001 · Cited by 5
Triglycerides, HDL cholesterol and atherogenic dyslipidaemia in the 2019 European guidelines for the management of dyslipidaemias
Pedro‐Botet, J., Ascaso, J. F., Blasco, M., Brea, Á., Díaz, Á., Hernández‐Mijares, A., Pintó, X., & Millán, J. (2020) · Clínica e Investigación en Arteriosclerosis (English Edition) · doi:10.1016/j.artere.2019.12.001 · Cited by 4
Postprandial lipemia and the relationship to health
Huggins, C. E., James, A. P., Bonham, M. P., Clark, K., & Lee, S. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-823914-8.00019-7 · Cited by 3
Postprandial implications in cardiovascular disease and potential markers to develop new therapies
Tudorache, I. F., Barbarossa, D., Daraban, B. S., Rizzo, R., Esposito, F. M., Coronelli, M. M., & Catapano, A. L. (2025) · European Atherosclerosis Journal · doi:10.56095/eaj.v4i2.104 · Cited by 2
Vascular Biology of the Metabolic Syndrome
Lee, J., & Choudhury, R. P. (2006) · CRC Press eBooks · doi:10.3109/9781420020601-5 · Cited by 2
Stochastic Models for Prodrug Targeting. 1. Diffusion of the Efflux Drug
Qi, X. (2006) · Molecular Pharmaceutics · doi:10.1021/mp050089l · Cited by 1
Macro- and Microvascular Disease in an Insulin-Resistant Pre-Diabetic Animal Model
Russell, J. C., & Proctor, S. D. (2008) · Humana Press eBooks · doi:10.1007/978-1-60327-116-5_8 · Cited by 1
Self-citation
Role of angiopoietin-like 3 and 4 in triacylglycerol metabolism : from population studies to molecular mechanisms of action
Robciuc, M. R. (2012) · Työväentutkimus Vuosikirja
Experimental and computational studies on lipoprotein lipolysis at acidic pH
Lähdesmäki, K. (2010) · Työväentutkimus Vuosikirja
Efeitos da dieta vegetariana no metabolismo de quilomícrons e aspectos qualitativos da lipoproteína de alta densidade (HDL)
Vinagre, J. C. (2010) · doi:10.11606/t.5.2010.tde-21122010-120737
Avaliação do metabolismo de quilomícrons artificiais em pacientes obesas e não obesas, portadoras da síndrome dos ovários policísticos
Rocha, M. P. (2007) · doi:10.11606/t.5.2007.tde-11032008-161037
Intestinal postprandial chylomicrons: state of the union between liver, gut and dyslipidemia?
Proctor, S. D., Vine, D. F., Botham, K. M., Mamo, J. C. L., & Cabezas, M. C. (2008) · Future Lipidology · doi:10.2217/17460875.3.5.473
Self-citation
Cholesterol metabolism and noncholesterol sterol distribution in lipoproteins of Type 1 diabetes
Suryadevara, R. S. (2008) · Future Lipidology · doi:10.2217/17460875.3.1.17
Multigene Assays: The Changing Paradigm of Personalized Medicine in Breast Cancer
Gaur, G. (2017) · MOJ Cell Science & Report · doi:10.15406/mojcsr.2017.04.00097
The role of novel red yeast rice formulation to modulate lipid metabolism and reduce dyslipidemia and vascular disease in the JCR:LA-cp rat
Wu, S. (2013) · ERA: Education and Research Archive (University of Alberta) · doi:10.7939/r3xk84x3b
2型糖尿病におけるエゼチミブの小型高密度低比重リポ蛋白低下作用トリグリセリド-リッチリポ蛋白との関係
賀子, 原., & Hara, N. (2014) · 糖尿病 · doi:10.11213/tonyobyo.57.1
Nutritional Factors Impacting Intestinal Lipid Metabolism Using a Model of Low Birth Weight Swine
Fontaine, M. A. (2018) · ERA: Education and Research Archive (University of Alberta) · doi:10.7939/r3dr2pq51
Differentiation of submicron particles in blood plasma of farm poultry by optical method and multivariate regression method
Lovtsova, L. G., Zabelina, M. V., Lovtsov, I. V., & Uskov, K. Y. (2023) · AIP conference proceedings · doi:10.1063/5.0148365
Monoclonal antibody chP3R99 reduces subendothelial retention of atherogenic lipoproteins in Insulin-Resistant rats: Acute treatment versus long-term protection as an idiotypic vaccine for atherosclerosisPreprint
Soto, Y., Hernández, A., Sarduy, R., Brito, V., Marleau, S., Vine, D. F., Vázquez, A. M., & Proctor, S. D. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.08.30.555546
Self-citation

Authors: Proctor, S. D., Vine, D. F., & Mamo, J. C. L.
Affiliations: Curtin University (AU)
ORCID: Proctor, Spencer D.
Vine, Donna F.
Mamo, John C.L.
Venue: Arteriosclerosis, Thrombosis, and Vascular Biology
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2004-11
Volume: 24
Issue: 11
Pages: 2162-2167
ISSN: 1079-5642 (ISSN-L)
1524-4636
DOI: 10.1161/01.atv.0000143859.75035.5a
OpenAlex: W1966788643
Cited by: 103
References: 30
Citations by year: 2025: 5 · 2024: 4 · 2023: 7 · 2022: 7 · 2021: 5 · 2020: 6 · 2019: 2 · 2018: 6 · 2017: 3 · 2015: 4 · 2014: 1 · 2013: 4 · 2012: 4
FWCI: 3.47
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Arteriosclerosis Thrombosis and Vascular Biology (publishedVersion)
PubMed (publishedVersion)
Funders: National Heart Foundation of Australia
Medical Research Council
National Health and Medical Research Council (229030)
National Medical Research Council
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Cholesterol and Lipid Metabolism
Life Sciences › Immunology and Microbiology › Immunology › Atherosclerosis and Cardiovascular Diseases
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
Keywords: arterial permeability, apolipoprotein B-100, apolipoprotein B-48, chylomicron remnants, low-density lipoprotein, atherogenesis, cholesterol accumulation, carotid artery, in situ perfusion, extracellular matrix, lipoprotein phenotype
MeSH terms: Animals, Apolipoproteins B, Capillary Permeability, Humans, Infusions, Intra-Arterial, Lipoproteins, LDL, Particle Size, Rabbits, Microscopy, Confocal, Imaging, Three-Dimensional

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Arterial Permeability and Efflux of Apolipoprotein B–Containing Lipoproteins Assessed by In Situ Perfusion and Three-Dimensional Quantitative Confocal Microscopy

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks