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The DOI matches its Crossref record; 68 of the 68 references it cites were found in a registry or an index.

Peripheral Arterial Disease in the Elderly: The Rotterdam Study

Open access
Meijer, Wouter T., Hoes, Arno W., Rutgers, Dominique, Bots, Michiel L., Hofman, Albert, Grobbee, Diederick E.·1998·Arteriosclerosis, Thrombosis, and Vascular Biology

Abstract

Abstract —To assess the age- and sex-specific prevalence of peripheral arterial disease (PAD) and intermittent claudication (IC) in an elderly population, we performed a population-based study in 7715 subjects (40% men, 60% women) aged 55 years and over. The presence of PAD and IC was determined by measuring the ankle-arm systolic blood pressure index (AAI) and by means of the World Health Organization/Rose questionnaire, respectively. PAD was considered present when the AAI was <0.90 in either leg. The prevalence of PAD was 19.1% (95% confidence interval, 18.1% to 20.0%): 16.9% in men and 20.5% in women. Symptoms of IC were reported by 1.6% (95% confidence interval, 1.3% to 1.9%) of the study population (2.2% in men, 1.2% in women). Of those with PAD, 6.3% reported symptoms of IC (8.7% in men, 4.9% in women), whereas in 68.9% of those with IC an AAI below 0.90 was found. Subjects with an AAI <0.90 were more likely to be smokers, to have hypertension, and to have symptomatic or asymptomatic cardiovascular disease compared with subjects with an AAI of 0.90 or higher. The authors conclude that the prevalence of PAD in the elderly is high whereas the prevalence of IC is rather low, although both prevalences clearly increase with advancing age. The vast majority of PAD patients reports no symptoms of IC.

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Metadata

Authors
Meijer, W. T., Hoes, A. W., Rutgers, D., Bots, M. L., Hofman, A., & Grobbee, D. E.
Venue
Arteriosclerosis, Thrombosis, and Vascular Biology
Published
1998-02
Volume
18
Issue
2
Pages
185-192
ISSN
  • 1079-5642 (ISSN-L)
  • 1524-4636
OpenAlex
W1989769687
Cited by
770
References
68
FWCI
11.47
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Peripheral Arterial Disease in the Elderly: The Rotterdam Study. https://app.cochat.ai/papers/10.1161/01.atv.18.2.185
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Meijer, W. T., Hoes, A. W., Rutgers, D., Bots, M. L., Hofman, A., & Grobbee, D. E. (1998). Peripheral Arterial Disease in the Elderly: The Rotterdam Study. Arteriosclerosis, Thrombosis, and Vascular Biology. https://doi.org/10.1161/01.atv.18.2.185

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