Impact of Obesity on Plasma Natriuretic Peptide Levels

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1. β-Adrenergic and Atrial Natriuretic Peptide Interactions on Human Cardiovascular and Metabolic Regulation
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2. New Pharmacological Strategies to Increase cGMP
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3. Bone morphogenetic protein 10: a novel risk marker of ischaemic stroke in patients with atrial fibrillation
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4. The role of dietary salt in metabolism and energy balance: Insights beyond cardiovascular disease
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5. Relation of Obesity to Circulating B-Type Natriuretic Peptide Concentrations in Blacks
   Ervin Ray Fox, Solomon K. Musani, Aurelian Bidulescu, Harsha Santheshivara Nagarajarao, Tandaw E. Samdarshi, Samson Y. Gebreab, Jung Hye Sung, Michael W. Steffes, Thomas J. Wang, Herman A. Taylor et al. · 2011 · Circulation
6. Medical and Economic Long-term Effects of B-Type Natriuretic Peptide Testing in Patients with Acute Dyspnea
   Tobias Breidthardt, Kirsten Laule, Anne-Henny Strohmeyer, Christian J. A. Schindler, Sophie Meier, Michael Fischer, André Scholer, Markus Noveanu, Michael Christ, André Paul Perruchoud et al. · 2007 · Clinical Chemistry
7. The association of liver enzymes with biomarkers of subclinical myocardial damage and structural heart disease
   Mariana Lazo, Jonathan Rubin, Jeanne M. Clark, Josef Coresh, Andrea L.C. Schneider, Chiadi E. Ndumele, Ron Cornelis Hoogeveen, Christie Mitchell Ballantyne, Elizabeth Selvin · 2014 · Journal of Hepatology
8. A novel peptide adropin in cardiovascular diseases
   Liang Li, Wei Xie, Xi‐Long Zheng, Weidong Yin, Chao‐Ke Tang · 2015 · Clinica Chimica Acta
9. Effect of Testosterone on Natriuretic Peptide Levels
   Katherine N. Bachmann, Shi Huang, H Lee, Laura E. Dichtel, Deepak K. Gupta, John C. Jr Burnett, Karen Klahr Miller, Thomas J. Wang, Joel S. Finkelstein · 2019 · Journal of the American College of Cardiology
10. Reciprocal regulation of natriuretic peptide receptors by insulin in adipose cells
    Hideaki Nakatsuji, Norikazu Maeda, Toshiyuki Hibuse, Aki Hiuge, Ayumu Hirata, Yohei Kuroda, Ken Kishida, Shinji Kihara, Tohru Funahashi, Iichiro Shimomura · 2010 · Biochemical and Biophysical Research Communications
11. Relationship of B‐type natriuretic peptide and anemia in patients with and without heart failure: A substudy from the Breathing Not Properly (BNP) Multinational Study
    Alan H.B. Wu, Torbjørn Omland, Cathrine Wold Knudsen, James McCord, Richard M. Nowak, Judd E. Hollander, Philippe Duc, Alan B. Storrow, William T. Abraham, Paul Clopton et al. · 2005 · American Journal of Hematology
12. Fat Oxidation, Hormonal and Plasma Metabolite Kinetics during a Submaximal Incremental Test in Lean and Obese Adults
    Lanzi, Stefano, Codecasa, Franco, Cornacchia, Mauro, Maestrini, Sabrina, Salvadori, Alberto, Brunani, Amelia, Malatesta, Davide · 2014 · PLoS ONE
13. Left ventricular hypertrophy and myocardial fibrosis in heart failure with preserved ejection fraction: mechanisms and treatment
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14. Angiogenesis and biomarkers of cardiovascular risk in adults with metabolic syndrome
    Mario Siervo, Daniela Ruggiero, Rossella Sorice, Teresa Nutile, Mario Aversano, Blossom C. M. Stephan, Marina Ciullo · 2010 · Journal of Internal Medicine
15. Role of Obesity in Cardiomyopathy and Pulmonary Hypertension
    Charles S. Dela Cruz, Richard A. Matthay · 2009 · Clinics in Chest Medicine
16. Phosphodiesterase‐5A and neutral endopeptidase activities in human adipocytes do not control atrial natriuretic peptide‐mediated lipolysis
    Cédric Moro, Eva Klimčáková, Max Lafontan, M Berlan, Jean Galitzky · 2007 · British Journal of Pharmacology
17. Targeting cardiac natriuretic peptides in the therapy of diabetes and obesity
    Cédric Moro · 2016 · Expert Opinion on Therapeutic Targets
18. Treatment with atrial natriuretic peptide induces adipose tissue browning and exerts thermogenic actions in vivo
    Haruka Kimura, Tomohisa Nagoshi, Yuhei Oi, Akira Yoshii, Yoshiro Tanaka, H Takahashi, Yusuke Kashiwagi, Toshikazu D. Tanaka, Michihiro Yoshimura · 2021 · Scientific Reports
19. Natriuretic Peptides
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20. Sex Differences in Lipolysis‐Regulating Mechanisms in Overweight Subjects: Effect of Exercise Intensity
    Moro, Cédric, Pillard, Fabien, de Glisezinski, Isabelle, Crampes, François, Thalamas, Claire, Harant, Isabelle, Marques, Marie‐Adeline, Lafontan, Max, Berlan, Michel · 2007 · Obesity
21. Association of N-Terminal Pro–Brain Natriuretic Peptide Concentration in Early Pregnancy With Development of Hypertensive Disorders of Pregnancy and Future Hypertension
    Alisse K. Hauspurg, Derek J. Marsh, Rebecca B. McNeil, C. Noel Bairey Merz, Philip Greenland, Adam C. Straub, Caroline E. Rouse, William A. Grobman, Victoria L. Pemberton, Robert M. Silver et al. · 2022 · JAMA Cardiology
22. JCS/JHFS 2025 Guideline on Diagnosis and Treatment of Heart Failure
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23. Conversion formula from B-type natriuretic peptide to N-terminal proBNP values in patients with cardiovascular diseases
    Shintaro Kasahara, Yasuhiko Sakata, Kotaro Nochioka, Masanobu Miura, Ruri Abe, Masayuki Sato, Hajime Aoyanagi, Takahide Fujihashi, Shinsuke Yamanaka, Takashi Shiroto et al. · 2019 · International Journal of Cardiology
24. Impact of Increased Body Mass Index on Accuracy of B-Type Natriuretic Peptide (BNP) and N-Terminal proBNP for Diagnosis of Decompensated Heart Failure and Prediction of All-Cause Mortality
    Robert H. Christenson, Hassan Mohamed El-Said Azzazy, Show‐Hong Duh, Susan M. Maynard, Stephen L. Seliger, Christopher R. deFilippi · 2010 · Clinical Chemistry
25. New Conversion Formula Between B-Type Natriuretic Peptide and N-Terminal-Pro-B-Type Natriuretic Peptide ― Analysis From a Multicenter Study ―
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26. Impact of age, phenotype and cardio‐renal function on plasma C ‐type and B ‐type natriuretic peptide forms in an adult population
    Timothy C. R. Prickett, Robert C. Olney, Vicky A. Cameron, M. J. Ellis, Mark Richards, Eric Arnold Espiner · 2012 · Clinical Endocrinology
27. Overweight is associated with improved survival and outcomes in patients with atrial fibrillation
    Juan Wang, Yanmin Yang, Jun Zhu, Han Zhang, Xing‐hui Shao, Li Tian, Bi Huang, Litian Yu, Xin Gao, Man Wang · 2014 · Clinical Research in Cardiology
28. Growth-Differentiation Factor-15 Improves Reclassification for the Diagnosis of Heart Failure with Normal Ejection Fraction in Morbid Obesity
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29. Obstructive Sleep Apnea and Plasma Natriuretic Peptide Levels in a Community-Based Sample
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30. Second messenger signaling mechanisms of the brown adipocyte thermogenic program: an integrative perspective
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31. Troponin, B‐type natriuretic peptides and outcomes in severe heart failure: Differences between ischemic and dilated cardiomyopathies
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32. Natriuretic peptides BNP and NT-pro-BNP: established laboratory markers in clinical practice or just perspectives?
    Rudolf Pfister, C. A. Schneider · 2004 · Clinica Chimica Acta
33. NT‐proBNP and All‐Cause and Cardiovascular Mortality in US Adults: A Prospective Cohort Study
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34. Observational Study of Obstructive Sleep Apnea in Wake-Up Stroke: The SLEEP TIGHT Study
    Brian B. Koo, Daawn M. Bravata, Lauren A. Tobias, Jason S. Mackey, Edward J. Miech, Marianne Sassi Matthias, Stephanie M. Stahl, Jason Jonathon Sico, Carlos A. Vaz Fragoso, Linda S. Williams et al. · 2016 · Cerebrovascular Diseases
35. Biomarkers for Prediction of Cardiovascular Events
    Kiran Musunuru, Roger S Blumenthal · 2007 · New England Journal of Medicine
36. LXRα improves myocardial glucose tolerance and reduces cardiac hypertrophy in a mouse model of obesity-induced type 2 diabetes
    Megan V. Cannon, Herman H.W. Silljé, Jürgen W. A. Sijbesma, Mohsin A.F. Khan, Knut Rune Steffensen, Wiek H. van Gilst, Rudolf A. de Boer · 2015 · Diabetologia
37. Molecular and genetic aspects of guanylyl cyclase natriuretic peptide receptor-A in regulation of blood pressure and renal function
    Kailash N. Pandey · 2018 · Physiological Genomics
38. Clinical Applications of Natriuretic Peptides in Heart Failure and Atrial Fibrillation
    Masako Baba, Kentaro Yoshida, Masaki Ieda · 2019 · International Journal of Molecular Sciences
39. The search for a pathophysiological link between gender, cardiac endocrine function, body mass regulation and cardiac mortality: Proposal for a working hypothesis
    Aldo Clerico, Marianna Fontana, Simona Vittorini, Michele Emdin · 2009 · Clinica Chimica Acta
40. Relation of N-terminal pro-brain natriuretic peptide levels and their prognostic power in chronic stable heart failure to obesity status
    Lutz Frankenstein, Andrew Remppis, Manfred Nelles, B. Schaelling, Dieter Schellberg, Hugo Albert Katus, Christian Zugck · 2008 · European Heart Journal
41. Natriuretic peptides as markers of preclinical cardiac disease in obesity
    Grandi, A. M., Laurita, E., Selva, E., Piantanida, E., Imperiale, D., Giovanella, L., Guasti, L., Venco, A. · 2004 · European Journal of Clinical Investigation
42. Acute Metabolic Influences on the Natriuretic Peptide System in Humans
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43. Obesity
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44. Regulation of metabolism by cGMP
    Alexander Pfeifer, Ana Kilić, Linda Sarah Hoffmann · 2013 · Pharmacology & Therapeutics
45. Obesity: The Perfect Storm for Heart Failure
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46. B-type natriuretic peptide increases after gastric bypass surgery and correlates with weight loss
    Eric M. Changchien, Shushmita M. Ahmed, Francesca Betti, Jennifer T. Higa, Kate Kiely, Tina Hernandez‐Boussard, John M. Morton · 2011 · Surgical Endoscopy
47. The Atrial Natriuretic Peptide and Guanylyl Cyclase-A System Modulates Pancreatic β-Cell Function
    Ana Belén Ropero, Sergi Soriano, Eva Tudurí, Laura Marroquí, Noèlia Téllez, Birgit Gaßner, Pablo Juan-Picó, Eduard Montanya, Iván Quesada, Michaela Kühn et al. · 2010 · Endocrinology
48. Weight Loss, Saline Loading, and the Natriuretic Peptide System
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49. Body Mass Index and Adverse Outcomes in Elderly Patients With Atrial Fibrillation
    Keitaro Senoo, Gregory Y.H. Lip · 2015 · Stroke
50. Blood pressure-independent renoprotection in diabetic rats treated with AT1 receptor–neprilysin inhibition compared with AT1 receptor blockade alone
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51. Natriuretic peptides in the control of lipid metabolism and insulin sensitivity
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52. Racial/Ethnic Differences in B-Type Natriuretic Peptide Levels and Their Association With Care and Outcomes Among Patients Hospitalized With Heart Failure
    Selim R. Krim, Rey Percival Vivo, Nassim Rostane Krim, Feng Qian, Margueritte Cox, Héctor O. Ventura, Adrian F. Hernandez, Deepak L. Bhatt, Gregg C. Fonarow · 2013 · JACC Heart Failure
53. Endocrine functions of the heart: from bench to bedside
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54. Differential response of the natriuretic peptide system to weight loss and exercise in overweight or obese patients
    Haufe, Sven, Kaminski, Jana, Utz, Wolfgang, Haas, Verena, Mähler, Anja, Daniels, Martin A., Birkenfeld, Andreas L., Lichtinghagen, Ralf, Luft, Friedrich C., Schulz-Menger, Jeanette et al. · 2015 · Journal of Hypertension
55. Inflamed adipose tissue: A culprit underlying obesity and heart failure with preserved ejection fraction
    Chenyu Li, Donglu Qin, Jiarui Hu, Yang Yang, Die Hu, Bilian Yu · 2022 · Frontiers in Immunology
56. Serial ST2 Testing in Hospitalized Patients With Acute Heart Failure
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57. Predictive value of plasma B-type natriuretic peptide for ischemic stroke: A community-based longitudinal study
    Tomohiro Takahashi, Motoyuki Nakamura, Toshiyuki Onoda, Masaki Ohsawa, Kozo Tanno, Kazuyoshi Itai, Kiyomi Sakata, Masafumi Sakuma, Fumitaka Tanaka, Shinji Makita et al. · 2009 · Atherosclerosis
58. Modulation of natriuretic peptide receptors in human adipose tissue: molecular mechanisms behind the “natriuretic handicap” in morbidly obese patients
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59. Linkage disequilibrium analyses of natriuretic peptide precursor B locus reveal risk haplotype conferring high plasma BNP levels
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60. B-type natriuretic peptide-guided versus symptom-guided therapy in outpatients with chronic heart failure
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61. INTERACTING DISCIPLINES: Cardiac natriuretic peptides and obesity: perspectives from an endocrinologist and a cardiologist
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62. Diagnostic and prognostic considerations for use of natriuretic peptides in obese patients with heart failure
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63. Natriuretic peptides – physiology, pathophysiology and clinical use in heart failure
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64. Blood haemoglobin is an independent predictor of B-type natriuretic peptide (BNP)
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65. Natriuretic peptides: linking heart and adipose tissue in obesity and related conditions – a systematic review
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66. N-Terminal Pro-Brain Natriuretic Peptide (NT-proBNP) and Risk of Hypertension in the Atherosclerosis Risk in Communities (ARIC) Study
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67. Genome-Wide Association Study Implicates Atrial Natriuretic Peptide Rather Than B-Type Natriuretic Peptide in the Regulation of Blood Pressure in the General Population
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68. Biomarkers for cardiovascular disease: challenges and future directions
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69. Effect of liraglutide on atrial natriuretic peptide, adrenomedullin, and copeptin in PCOS
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70. Relation of B-Type Natriuretic Peptide Levels to Body Mass Index After Comprehensive Lifestyle Changes
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71. B-type natriuretic peptide, a marker of asymptomatic left ventricular dysfunction in type 2 diabetic patients
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72. Do estrogens enhance activation of brown and beiging of adipose tissues?
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73. The use of B‐type natriuretic peptide in the management of elderly patients with acute dyspnoea
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74. N-terminal pro-brain-type natriuretic peptide (NT-pro-BNP) and mortality risk in early inflammatory polyarthritis: results from the Norfolk Arthritis Registry (NOAR)
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75. Amino-Terminal Pro–B-Type Natriuretic Peptides: Testing in General Populations
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76. ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult—Summary Article A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2001 Guidelines for the Evaluation and Management of Heart Failure) Developed in Collaboration With the American College of Chest Physicians and the International Society for Heart and Lung Transplantation
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77. A gut-heart connection in cardiometabolic regulation
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78. Use of B-type natriuretic peptide outside of the emergency department
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79. The Impacts of Obesity on the Cardiovascular and Renal Systems: Cascade of Events and Therapeutic Approaches
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80. Determination of the B-type Natriuretic Peptide Level as a Criterion for Abnormalities in Japanese Individuals in Routine Clinical Practice: The J-ABS Multi-center Study (Japan Abnormal BNP Standard)
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81. Reduced levels of N-terminal-proatrial natriuretic peptide in hypertensive patients with metabolic syndrome and their relationship with left ventricular mass
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82. Factors influencing brain natriuretic peptide levels in healthy pregnant women
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83. Effect of bariatric surgery on heart failure
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84. Oxidative Stress and Heart Failure
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85. The T-381C SNP in BNP gene may be modestly associated with type 2 diabetes: an updated meta-analysis in 49 279 subjects
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86. Natriuretic peptides and cardiovascular damage in the metabolic syndrome: molecular mechanisms and clinical implications
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87. Cardiac natriuretic peptide deficiency sensitizes the heart to stress-induced ventricular arrhythmias via impaired CREB signalling
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88. Noninvasive determinants of pulmonary hypertension in interstitial lung disease
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89. Predialysis NTproBNP Predicts Magnitude of Extracellular Volume Overload in Haemodialysis Patients
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90. Cardiokines as Modulators of Stress-Induced Cardiac Disorders
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91. Atrial natriuretic peptide regulates lipid mobilization and oxygen consumption in human adipocytes by activating AMPK
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92. Perception of symptoms is out of proportion to cardiac pathology in patients with “diastolic heart failure”
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93. Impact of the look AHEAD intervention on NT-pro brain natriuretic peptide in overweight and obese adults with diabetes
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94. NT-proBNP is not elevated in patients with obstructive sleep apnoea
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95. Cardiovascular Biomarkers of Obesity and Overlap With Cardiometabolic Dysfunction
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96. Angiotensin II Receptor Antagonist Attenuates Expression of Aging Markers in Diabetic Mouse Heart
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97. Association of a Polymorphism in the Lipin 1 Gene With Systolic Blood Pressure in Men
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98. Impairment of the Natriuretic Peptide System in Follitropin Receptor Knockout Mice and Reversal by Estradiol: Implications for Obesity-Associated Hypertension in Menopause
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99. Neuroendocrine changes in sleep apnea
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100. Gastric Bypass Surgery Elevates NT-ProBNP Levels
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