Cited by 1,284Iron Metabolism and DisordersAcute Myocardial Infarction ResearchCardiovascular Health and Risk Factors

The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.

High stored iron levels are associated with excess risk of myocardial infarction in eastern Finnish men

Salonen, J T, Nyyssönen, K, Korpela, H, Tuomilehto, J, Seppänen, R, Salonen, R·1992·Circulation

Open this paper in CoChat — free account

Abstract

BACKGROUND: Iron can induce lipid peroxidation in vitro and in vivo in humans and has promoted ischemic myocardial injury in experimental animals. We tested the hypothesis that high serum ferritin concentration and high dietary iron intake are associated with an excess risk of acute myocardial infarction. METHODS AND RESULTS: Randomly selected men (n = 1,931), aged 42, 48, 54, or 60 years, who had no symptomatic coronary heart disease at entry, were examined in the Kuopio Ischaemic Heart Disease Risk Factor Study (KIHD) in Eastern Finland between 1984 and 1989. Fifty-one of these men experienced an acute myocardial infarction during an average follow-up of 3 years. On the basis of a Cox proportional hazards model adjusting for age, examination year, cigarette pack-years, ischemic ECG in exercise test, maximal oxygen uptake, systolic blood pressure, blood glucose, serum copper, blood leukocyte count, and serum high density lipoprotein cholesterol, apolipoprotein B, and triglyceride concentrations, men with serum ferritin greater than or equal to 200 micrograms/l had a 2.2-fold (95% CI, 1.2-4.0; p less than 0.01) risk factor-adjusted risk of acute myocardial infarction compared with men with a lower serum ferritin. An elevated serum ferritin was a strong risk factor for acute myocardial infarction in all multivariate models. This association was stronger in men with serum low density lipoprotein cholesterol concentration of 5.0 mmol/l (193 mg/dl) or more than in others. Also, dietary iron intake had a significant association with the disease risk in a Cox model with the same covariates. CONCLUSIONS: Our data suggest that a high stored iron level, as assessed by elevated serum ferritin concentration, is a risk factor for coronary heart disease.

Integrity signals

Registry

Crossref · 10.1161/01.cir.86.3.803

Cites

38 of 38 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Free radicals in biology and medicine
Gutteridge, J. M. C. (1991) · General Pharmacology The Vascular System · doi:10.1016/0306-3623(91)90478-o · Cited by 17,178
Beyond Cholesterol
Epstein, F. H., Steinberg, D. I., Parthasarathy, S., Carew, T. E., Khoo, J. C., & Witztum, J. L. (1989) · New England Journal of Medicine · doi:10.1056/nejm198904063201407 · Cited by 6,425
[1] Role of free radicals and catalytic metal ions in human disease: An overview
Halliwell, B., & Gutteridge, J. M. C. (1990) · Methods in Enzymology · doi:10.1016/0076-6879(90)86093-b · Cited by 4,994
Cardiovascular Survey Methods.
Rose, G., & Blackburn, H. (1968) · Annals of Internal Medicine · doi:10.7326/0003-4819-69-6-1335_2 · Cited by 3,090
BMPD statistical software manual
Dixon, W. (1988) · University of California Press eBooks · Cited by 2,536
Oxygen radicals and human disease
CROSS, C. E., HALLIWELL, B., BORISH, E. T., PRYOR, W. A., AMES, B. N., SAUL, R. L., McCORD, J. M., & HARMAN, D. (1987) · Annals of Internal Medicine · doi:10.7326/0003-4819-107-4-526 · Cited by 1,856
Seven Countries: A Multivariate Analysis of Death and Coronary Heart Disease.
(1980) · Annals of Internal Medicine · doi:10.7326/0003-4819-93-5-786_2 · Cited by 1,426
Autoantibody against oxidised LDL and progression of carotid atherosclerosis
Salonen, J. T., Korpela, H., Salonen, R., Nyyssönen, K., Ylä‐Herttuala, S., Yamamoto, R., Butler, S., Palinski, W., & Witztum, J. L. (1992) · The Lancet · doi:10.1016/0140-6736(92)90926-t · Cited by 1,311
IRON AND THE SEX DIFFERENCE IN HEART DISEASE RISK
Sullivan, J. (1981) · The Lancet · doi:10.1016/s0140-6736(81)92463-6 · Cited by 969
Menopause and Coronary Heart Disease
Gordon, T., Kannel, W. B., Hjortland, M. C., & McNAMARA, P. M. (1978) · Annals of Internal Medicine · doi:10.7326/0003-4819-89-2-157 · Cited by 904

Flagged first, then by citations

Show all 38 references

Sorted by citations

Items 701–800 of 1,001

Association of Exercise-Induced, Silent ST-Segment Depression With the Risk of Stroke and Cardiovascular Diseases in Men
Kurl, S., Laukkanen, J. A., Tuomainen, T., Rauramaa, R., Lakka, T. A., Salonen, R. M., Eränen, J., Sivenius, J., & Salonen, J. T. (2003) · Stroke · doi:10.1161/01.str.0000078564.46376.0a · Cited by 18
Iron treatment: Impact of safety issues
Fishbane, S. (1998) · American Journal of Kidney Diseases · doi:10.1016/s0272-6386(98)70179-9 · Cited by 18
Opposite Associations of Carbohydrate-Deficient Transferrin and γ-Glutamyltransferase With Prevalent Coronary Heart Disease
Jousilahti, P., Vartiainen, E. A., Alho, H., Poikolainen, K., & Sillanaukee, P. (2002) · Archives of Internal Medicine · doi:10.1001/archinte.162.7.817 · Cited by 17
Iron Metabolism and Development of Atherosclerosis
Auer, J., Berent, R., Weber, T., & Eber, B. (2002) · Circulation · doi:10.1161/01.cir.0000019984.69119.4f · Cited by 18
Serum Iron, Transferrin Saturation, Ferritin, and Dietary Data in Age-Related Macular Degeneration
Richer, S., Rudy, D., Statkute, L., Karofty, K., & Frankowski, J. (2002) · American Journal of Therapeutics · doi:10.1097/00045391-200201000-00006 · Cited by 17
Variables associated with subclinical atherosclerosis among rheumatoid arthritis patients of Gulf Cooperative Council countries
Hannawi, S., Hannawi, H., Alokaily, F., & Salmi, I. A. (2020) · Saudi Medical Journal · doi:10.15537/smj.2020.2.24900 · Cited by 17
The Integrated Use of Heavy-Metal Pollution Indices and the Assessment of Metallic Health Risks in the Phreatic Groundwater Aquifer—The Case of the Oued Souf Valley in Algeria
Barkat, A., Bouaicha, F., Ziad, S., Mester, T., Sajtos, Z., Balla, D., Makhloufi, I., & Szabó, G. (2023) · Hydrology · doi:10.3390/hydrology10100201 · Cited by 17
Decoding ferroptosis: Revealing the hidden assassin behind cardiovascular diseases
Zhang, Z., Yang, Z., Wang, S., Wang, X., & Mao, J. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.116761 · Cited by 18
Iron stores in regular blood donors in Lagos, Nigeria
Akinbami, A., Adediran, Uche, Damulak, D., Adeyemo, & Akanmu (2013) · Journal of Blood Medicine · doi:10.2147/jbm.s42210 · Cited by 17
Serum ferritin and glucose homeostasis: change in the association by glycaemic state
Aregbesola, A., Virtanen, J. K., Voutilainen, S., Mursu, J., Lagundoye, A., Kauhanen, J., & Tuomainen, T. (2014) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.2628 · Cited by 17
Plasma ferritin levels, genetic variations in HFE gene, and coronary heart disease in Chinese: A case–control study
Shi, Y., Zhou, L., Huang, L., Lian, Y. T., Zhang, X. M., Guo, H., Wu, T., Cheng, L., & He, M. (2011) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2011.05.040 · Cited by 16
Understanding the Reactivity of CO3·– and NO2· Radicals toward S-Containing and Aromatic Amino Acids
Karmakar, S., & Datta, A. (2017) · The Journal of Physical Chemistry B · doi:10.1021/acs.jpcb.7b05186 · Cited by 17
Relation between the serum ferritin level and the risk for acute myocardial infarction.
Moradi, M., Fariba, F., & Mohasseli, A. S. (2015) · PubMed · Cited by 17
Serum homocysteine, cholesterol, retinol, alpha-tocopherol, glycosylated hemoglobin and inflammatory response during therapy with bevacizumab, oxaliplatin, 5-fluorouracil and leucovorin.
Melichar, B., Kalábová, H., Krčmová, L. K., Kašparová, M., Malířová, E., Melicharová, K., Pecka, M., Hyšpler, R., & Solichová, D. (2009) · PubMed · Cited by 17
Serum ferritin levels are associated with carotid atherosclerosis in Chinese postmenopausal women: the Shanghai Changfeng Study
Ma, H., Lin, H., Hu, Y., Li, X., He, W., Jin, X., Gao, J., Zhao, N., Song, B., Pan, B., et al. (2015) · British Journal Of Nutrition · doi:10.1017/s0007114515001944 · Cited by 17
The association between serum 25-hydroxyvitamin D3 concentration and risk of disease death in men: modification by magnesium intake
Mursu, J., Nurmi, T., Voutilainen, S., Tuomainen, T., & Virtanen, J. K. (2015) · European Journal of Epidemiology · doi:10.1007/s10654-015-0006-9 · Cited by 17
Meal-based intake assessment tool: relative validity when determining dietary intake of Fe and Zn and selected absorption modifiers in UK men
Heath, A. M., Roe, M. A., Oyston, S. L., & Fairweather‐Tait, S. J. (2005) · British Journal Of Nutrition · doi:10.1079/bjn20041324 · Cited by 17
Chapter 7 Biomarkers in Long‐Term Vegetarian Diets
Benzie, I. F. F., & Wachtel-Galor, S. (2009) · Advances in clinical chemistry · doi:10.1016/s0065-2423(09)47007-0 · Cited by 21
Treatment of Anemia in Heart Failure
Jelani, Q., & Katz, S. D. (2010) · Cardiology in Review · doi:10.1097/crd.0b013e3181e71150 · Cited by 17
Time-course of changes in plasma levels of trace elements after thrombolysis during the acute phase of myocardial infarction in humans
Pucheu, S., Coudray, C., Vanzetto, G., Favier, A. E., Machecourt, J., & de Leiris, J. (1995) · Biological Trace Element Research · doi:10.1007/bf02790115 · Cited by 17
Trace Element and Mineral Nutrition in Ischemic Heart Disease
Klevay, L. M. (2000) · Humana Press eBooks · doi:10.1007/978-1-59259-040-7_15 · Cited by 17
No sex differences in immunisation rates of British south Asian children: the effect of migration?: Table 1
Martineau, A. R., White, M. J., & Bhopal, R. S. (1997) · BMJ · doi:10.1136/bmj.314.7081.642 · Cited by 18
The Potential Role of Antioxidants in the Prevention of Atherosclerosis
Illingworth, D. R. (1993) · Journal of Nutritional Science and Vitaminology · doi:10.3177/jnsv.39.supplement_s43 · Cited by 17
Atherosclerosis, thrombosis and inflammation: a problem of linkage
Tracy, R. P. (1997) · Fibrinolysis and Proteolysis · doi:10.1016/s0268-9499(97)80040-9 · Cited by 17
A Brief Review: The Implications of Iron Supplementation for Marathon Runners on Health and Performance
Zourdos, M. C., Sanchez-Gonzalez, M. A., & Mahoney, S. E. (2015) · Journal of Strength and Conditioning Research · doi:10.1519/jsc.0000000000000636 · Cited by 16
Natural products and ferroptosis: A novel approach for heart failure management
Zhang, Z., Yang, Z., Wang, S., Wang, X., & Mao, J. (2025) · Phytomedicine · doi:10.1016/j.phymed.2025.156783 · Cited by 17
Antioxidants into Nopal (Opuntia ficus-indica), Important Inhibitors of Free Radicals’ Formation
Castañeda‐Arriaga, R., Pérez‐González, A., Marino, T., Russo, N., & Galano, A. (2021) · Antioxidants · doi:10.3390/antiox10122006 · Cited by 16
Serum n-6 polyunsaturated fatty acids and risk of atrial fibrillation: the Kuopio Ischaemic Heart Disease Risk Factor Study
Tajik, B., Tuomainen, T., Isanejad, M., Salonen, J. T., & Virtanen, J. K. (2021) · European Journal of Nutrition · doi:10.1007/s00394-021-02780-0 · Cited by 17
Iron, Human Growth, and the Global Epidemic of Obesity
Sangani, R. G., & Ghio, A. J. (2013) · Nutrients · doi:10.3390/nu5104231 · Cited by 15
Association between serum ferritin and acute coronary heart disease: A population-based cohort study
Reyes, C., Pons, N. A., Rey‐Reñones, C., Basora, J., Arija, V., Tebé, C., & Flores‐Mateo, G. (2019) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2019.12.011 · Cited by 16
Serum ferritin and acute coronary syndrome: A strong prognostic factor?
Rodrı́guez, S., Tome, M. C.-P., Hernández-García, C., Arroyo, E., Juárez-Prera, R. A., Blanco-Palacios, G., & Abreu-González, P. (2011) · International Journal of Cardiology · doi:10.1016/j.ijcard.2011.07.052 · Cited by 16
Oxyphytosterol formation in humans: Identification of high vs. low oxidizers
Baumgartner, S., Mensink, R. P., den Hartog, G. J. M., Bast, A., Bekers, O., Husche, C., Lütjohann, D., & Plat, J. (2013) · Biochemical Pharmacology · doi:10.1016/j.bcp.2013.02.035 · Cited by 16
Association of Low Serum Iron Levels with Low-grade Inflammation and Hyperadiponectinemia in Community-living Elderly Women
Tsuboi, A., Watanabe, M., Kazumi, T., & Fukuo, K. (2013) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.16071 · Cited by 16
Siderophore‐Mimetic hydrogel for iron chelation therapy
Mohammadi, Z., Xie, S., Golub, A. L., Gehrke, S. H., & Berkland, C. J. (2011) · Journal of Applied Polymer Science · doi:10.1002/app.33562 · Cited by 16
Alterations in sympathetic nerve traffic in genetic haemochromatosis before and after iron depletion therapy: a microneurographic study
Seravalle, G., Piperno, A., Mariani, R., Pelloni, I., Facchetti, R., Dell’Oro, R., Cuspidi, C., Mancia, G., & Grassi, G. M. (2015) · European Heart Journal · doi:10.1093/eurheartj/ehv696 · Cited by 16
Spaceflight Metabolism and Nutritional Support
Smith, S. M., Lane, H. W., & Zwart, S. R. (2019) · Springer eBooks · doi:10.1007/978-1-4939-9889-0_13 · Cited by 19
Dietary Iron as a Risk Factor for Myocardial Infarction
Malaviarachchi, D., Veugelers, P. J., Yip, A. M., & MacLean, D. R. (2002) · Canadian Journal of Public Health · doi:10.1007/bf03405014 · Cited by 16
The role of (E)-4-hydroxy-2-nonenal in platelet activation by low density lipoprotein and iron
Selley, M. L., Bartlett, M., Czeti, A. L., & Ardlie, N. G. (1998) · Atherosclerosis · doi:10.1016/s0021-9150(98)00123-3 · Cited by 16
Improved Iron Status Parameters May Be a Benefit of Hormone Replacement Therapy
Penckofer, S. M., & Schwertz, D. W. (2000) · Journal of Women s Health & Gender-Based Medicine · doi:10.1089/152460900318632 · Cited by 16
The Cholesterol Controversy
Geurian, K. (1996) · The Annals of Pharmacotherapy · doi:10.1177/106002809603000512 · Cited by 9
Role of trace elements in coronary heart disease
Fields, M. (1999) · British Journal Of Nutrition · doi:10.1017/s0007114599000203 · Cited by 16
Twice the recommended daily allowance of iron is associated with an increase in plasma α-1 antichymotrypsin concentrations in Guatemalan school-aged children
Rosales, F. J., Kang, Y., Pfeiffer, B., Rau, A., Romero-Abal, M.-E., Erhardt, J. G., Solomons, N. W., & Biesalski, H. K. (2004) · Nutrition Research · doi:10.1016/j.nutres.2004.06.008 · Cited by 15
On the hydroperoxyl radical scavenging activity of two Edaravone derivatives: mechanism and kinetics
Pérez‐González, A., & Galano, A. (2013) · Journal of Physical Organic Chemistry · doi:10.1002/poc.3082 · Cited by 15
Iron Overload and Lipid Peroxidation in Biological Systems
Paula, M., Natacha, E., & Puntarulo, S. (2012) · InTech eBooks · doi:10.5772/46181 · Cited by 16
Iron Status Biomarkers and Cardiovascular Risk
Vaquero, M. P., García-Quismondo, Á., Cañizo, F. J., & Sánchez-Muniz, F. J. (2017) · InTech eBooks · doi:10.5772/intechopen.69040 · Cited by 15
Does resistance training have an effect on levels of ferritin and atherogenic lipids in postmenopausal women? – A pilot trial
Ward, L. J., Hammar, M. L., Lindh‐Åstrand, L., Berin, E., Lindblom, H., Rubèr, M., Holm, A. S., & Li, W. (2020) · Scientific Reports · doi:10.1038/s41598-020-60759-z · Cited by 17
Role of the Sulfur Atom on the Reactivity of Methionine toward OH Radicals: Comparison with Norleucine
Francisco‐Márquez, M., & Galano, A. (2009) · The Journal of Physical Chemistry B · doi:10.1021/jp900118f · Cited by 15
Serum iron, infection and inflammation; effects on coronary risk
Kervinen, H., Tenkanen, L., Palosuo, T., Roivainen, M., Manninen, V., & Mänttäri, M. (2004) · Scandinavian Cardiovascular Journal · doi:10.1080/14017430410011003 · Cited by 15
Association of serum ferritin levels with metabolic syndrome and subclinical coronary atherosclerosis in postmenopausal Korean women
Seo, S. K., Yun, B. H., Chon, S. J., Lee, Y. J., Han, E.-J., Park, J. H., Cho, S., Choi, Y. S., & Lee, B. S. (2014) · Clinica Chimica Acta · doi:10.1016/j.cca.2014.07.042 · Cited by 15
The evaluation of carotid intima-media thickness in children with beta-thalassaemia major
Doğan, M., & Çıtak, E. Ç. (2011) · Cardiology in the Young · doi:10.1017/s1047951111001053 · Cited by 15
Hyperlipoproteinemia impairs endothelium-dependent vasodilation.
Kraml, P. J., Syrovátka, P., Štípek, S., Fialová, L., Kopřivová, H., Potočková, J., & Anděl, M. (2004) · PubMed · Cited by 15
Toxicity Considerations When Revising the Nordic Nutrition Recommendations
Sandström, B. (1998) · Journal of Nutrition · doi:10.1093/jn/128.2.372s · Cited by 15
Increased Iron Content of Some Indian Foods Due to Cookware
Kollipara, U. K., & Brittin, H. C. (1996) · Journal of the American Dietetic Association · doi:10.1016/s0002-8223(96)00140-x · Cited by 15
Dietary iron intake and serum ferritin in relation to 7.5 years structure and function of large arteries in the SUVIMAX cohort
Vergnaud, A., Bertrais, S., Zureik, M., Galan, P., Blacher, J., Herçberg, S., & Czernichow, S. (2007) · Diabetes & Metabolism · doi:10.1016/j.diabet.2007.04.004 · Cited by 15
Dietary iron intake and risk of non-fatal acute myocardial infarction
Tavani, A., Gallus, S., Bosetti, C., Parpinel, M. T., Negri, E., & Vecchia, C. L. (2006) · Public Health Nutrition · doi:10.1079/phn2005869 · Cited by 15
Iron and cardiac ischemia: a natural, quasi‐random experiment comparing eligible with disqualified blood donors (CME)
Germain, M., Delage, G., Blais, C., Maunsell, E., Décary, F., & Grégoire, Y. (2013) · Transfusion · doi:10.1111/trf.12081 · Cited by 16
Aspirin reduces blood cholesterol in copper-deficient rats: A potential antioxidant agent?
Fields, M., Lewis, C. G., & Bureau, I. (2001) · Metabolism · doi:10.1053/meta.2001.22513 · Cited by 15
Available iron and zinc in major lean meat cuts and their contribution to the recommended trace element supply in Switzerland
Leonhardt, M., Kreuzer, M., & Wenk, C. (1997) · Food / Nahrung · doi:10.1002/food.19970410508 · Cited by 15
Chlamydia Pneumoniae Seropositivity and Cardiovascular Risk Factors: The InCHIANTI Study
Blanc, P., Corsi, A. M., Gabbuti, A., Peduzzi, C., Meacci, F., Olivieri, F., Lauretani, F., Francesco, M., & Ferrucci, L. (2004) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2004.52453.x · Cited by 15
Ascorbate promotes low density lipoprotein oxidation in the presence of ferritin
Dai, L., Winyard, P. G., Zhang, Z., Blake, D. R., & Morris, C. J. (1996) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/s0005-2760(96)00121-x · Cited by 15
Human macrophage metabolism of low density lipoprotein oxidized by stimulated neutrophils and ferritin
Abdalla, D. S. P., Costa-Rosa, L. F. B. P., Monteiro, H. P., Čampa, A., & Curi, R. (1994) · Atherosclerosis · doi:10.1016/0021-9150(94)90017-5 · Cited by 15
Vitamin E and the Risk of Coronary Disease
O’Keefe, J. H., & Lavie, C. J. (1993) · New England Journal of Medicine · doi:10.1056/nejm199311043291914 · Cited by 15
Life's Simple 7 and the risk of stroke in Finnish men: A prospective cohort study
Isiozor, N. M., Kunutsor, S. K., Voutilainen, A., Kauhanen, J., & Laukkanen, J. A. (2021) · Preventive Medicine · doi:10.1016/j.ypmed.2021.106858 · Cited by 15
Serum copper-to-zinc ratio and risk of incident pneumonia in caucasian men: a prospective cohort study
Kunutsor, S. K., Voutilainen, A., & Laukkanen, J. A. (2022) · BioMetals · doi:10.1007/s10534-022-00414-4 · Cited by 14
Iron in Drinking Water and its Impact on Human Health –A Study in Selected Units of Jalalabad Cantonment
Rahman, I., Wahab, M. A., Akter, M., & Mahanta, T. R. (2024) · Bangladesh Armed Forces medical journal. · doi:10.3329/bafmj.v56i2.73013 · Cited by 14
Associations Between Genetically Predicted Iron Status and Cardiovascular Disease Risk: A Mendelian Randomization Study
Barad, A., Clark, A. G., O'Brien, K. O., & Pressman, E. K. (2024) · Journal of the American Heart Association · doi:10.1161/jaha.124.034991 · Cited by 17
Cross‐country skiing is associated with lower all‐cause mortality: A population‐based follow‐up study
Laukkanen, J. A., Laukkanen, T., & Kunutsor, S. K. (2017) · Scandinavian Journal of Medicine and Science in Sports · doi:10.1111/sms.12980 · Cited by 15
Association of serum ferritin with coronary artery disease
Zhou, Y., Liu, T., Tian, C., Kang, P., & Jia, C. (2012) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2012.06.013 · Cited by 14
Iron metabolism in solid‑organ transplantation: how far are we from solving the mystery?
Małyszko, J., Levin-Iaina, N., Myśliwiec, M., Przybyłowski, P., & Durlik, M. (2012) · Polskie Archiwum Medycyny Wewnętrznej · doi:10.20452/pamw.1423 · Cited by 14
Associations of estimated Δ-5-desaturase and Δ-6-desaturase activities with stroke risk factors and risk of stroke: the Kuopio Ischaemic Heart Disease Risk Factor Study
Daneshmand, R., Kurl, S., Tuomainen, T., & Virtanen, J. K. (2017) · British Journal Of Nutrition · doi:10.1017/s000711451700054x · Cited by 15
Kinetics and mechanism of the β-alanine + OH gas phase reaction: A quantum mechanical approach
Cruz‐Torres, A., Galano, A., & Alvarez-Idaboy, J. R. (2005) · Physical Chemistry Chemical Physics · doi:10.1039/b507101a · Cited by 14
Poor Iron Status Is More Prevalent in Hispanic Than in Non-Hispanic White Older Adults in Massachusetts
Seaverson, E. L. D., Buell, J. S., Fleming, D. J., Bermúdez, O. I., Potischman, N. A., Wood, R. J., Chasan‐Taber, L., & Tucker, K. L. (2007) · Journal of Nutrition · doi:10.1093/jn/137.2.414 · Cited by 13
Influence of disease on iron status
Worwood, M. (1997) · Proceedings of The Nutrition Society · doi:10.1079/pns19970042 · Cited by 14
Iron stores and coronary artery disease
Pilote, L., Joseph, L., Bélisle, P., Robinson, K., Lente, F., & Tager, I. B. (2000) · Journal of Clinical Epidemiology · doi:10.1016/s0895-4356(99)00234-6 · Cited by 14
Can excess iron increase the risk for coronary heart disease and cancer?
Kelly, C. N. M. (2002) · Nutrition Bulletin · doi:10.1046/j.1467-3010.2002.00253.x · Cited by 14
Hypotransferrinemia of Chronically Hemodialyzed Patients
Kirschbaum, B. B. (1999) · Artificial Organs · doi:10.1046/j.1525-1594.1999.06328.x · Cited by 14
Parenteral Iron: Pharmacology and Clinical Use
Ifudu, O. (1998) · The Nephron journals/Nephron journals · doi:10.1159/000045183 · Cited by 14
Patient-Directed, Nonprescription Approaches to Cardiovascular Disease
Simon, H. B. (1994) · Archives of Internal Medicine · doi:10.1001/archinte.154.20.2283 · Cited by 15
Mechanisms of Metal Ion-Dependent Oxidation of Human Low Density Lipoprotein
Lynch, S. M., & Frei, B. B. (1996) · Journal of Nutrition · doi:10.1093/jn/126.suppl_4.1063s · Cited by 14
Epidemiological Studies on Antioxidants, Lipid Peroxidation and Atherosclerosis
Salonen, J. T. (1998) · Archives of toxicology. Supplement · doi:10.1007/978-3-642-46856-8_22 · Cited by 14
Effects of body iron stores and haemochromatosis genotypes on coronary heart disease outcomes in the Busselton health study
Fox, C., Cullen, D. J., Knuiman, M. W., Cumpston, G. N., Divitini, M., Rossi, E., Gochee, P., Powell, L. W., & Olynyk, J. K. (2002) · Journal of Cardiovascular Risk · doi:10.1097/00043798-200210000-00010 · Cited by 14
The 2015 Dietary Guidelines Advisory Committee Report Concerning Dietary Cholesterol
Williams, K. A., Sr., Krause, A. J., Shearer, S., & Devries, S. R. (2015) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2015.07.077 · Cited by 14
Iron metabolism in hemodialyzed patients – a story half told?
Małyszko, J., Koc‐Żórawska, E., Levin-Iaina, N., Slotki, I. N., Matuszkiewicz‐Rowińska, J., Głowińska, I., & Małyszko, J. S. (2014) · Archives of Medical Science · doi:10.5114/aoms.2014.47823 · Cited by 13
Association between iron status and incident coronary artery disease: a population based-cohort study
Guo, S., Mao, X., Li, X., & Ouyang, H. (2022) · Scientific Reports · doi:10.1038/s41598-022-22275-0 · Cited by 13
The Labile Iron Pool in Monocytes Reflects the Activity of the Atherosclerotic Process in Men With Chronic Cardiovascular Disease
Riško, P., Plátenı́k, J., Buchal, R., Potočková, J., & Kraml, P. J. (2017) · Physiological Research · doi:10.33549/physiolres.933368 · Cited by 13
High Consumption of Red Meat Is Associated with Excess Mortality Among African-American Women
Li, S., Palmer, J. R., & Rosenberg, L. A. (2020) · Journal of Nutrition · doi:10.1093/jn/nxaa282 · Cited by 13
Increased Iron Content of Food Due to Stainless Steel Cookware
PARK, J., & Brittin, H. C. (1997) · Journal of the American Dietetic Association · doi:10.1016/s0002-8223(97)00166-1 · Cited by 13
Relation of Iron Status to Prognosis After Acute Coronary Syndrome
Gürgöze, M. T., Kardys, I., Akkerhuis, K. M., Oemrawsingh, R. M., Groot, H. E., van der Harst, P., Umans, V. A. W. M., Kietselaer, B., Ronner, E., Lenderink, T., et al. (2022) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2021.12.022 · Cited by 13
Iron, Oxygen Radicals, and Disease
Nelson, S. K., & McCord, J. M. (1998) · Advances in molecular and cell biology · doi:10.1016/s1569-2558(08)60036-3 · Cited by 13
Association of dietary iron restriction with left ventricular remodeling after myocardial infarction in mice
Eguchi, A., Naito, Y., Iwasaku, T., Okuhara, Y., Morisawa, D., Sawada, H., Nishimura, K., Oboshi, M., Fujii, K., Mano, T., et al. (2015) · Heart and Vessels · doi:10.1007/s00380-014-0621-5 · Cited by 13
Free Radicals and Antioxidants in Atherosclerosis
Rice-Evans, C. A. (1995) · Elsevier eBooks · doi:10.1016/b978-012103520-4/50005-2 · Cited by 13
Iron and Heart Disease
Sempos, C. T., Gillum, R. F., & Looker, A. C. (2005) · Humana Press eBooks · doi:10.1007/978-1-59259-880-9_7 · Cited by 13
Iron deficiency anemia
Brigden, M. L. (1993) · Postgraduate Medicine · doi:10.1080/00325481.1993.11701645 · Cited by 14
Iron and oxidative injury A commentary on “Fatty acid-mediated iron translocation: A synergistic mechanism of oxidative injury” by D. Yao et al.
Kallianpur, A. R. (2005) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2005.07.014 · Cited by 13
Serum polyunsaturated fatty acids are not associated with the risk of severe depression in middle-aged Finnish men: Kuopio Ischaemic Heart Disease Risk Factor (KIHD) Study
Ruusunen, A. A., Virtanen, J. K., Lehto, S. M., Tolmunen, T., Kauhanen, J., & Voutilainen, S. (2010) · European Journal of Nutrition · doi:10.1007/s00394-010-0118-7 · Cited by 12
Serum long-chain omega-3 polyunsaturated fatty acids and future blood pressure in an ageing population
Nyantika, A. N., Tuomainen, T.-P., Kauhanen, J., Voutilainen, S., & Virtanen, J. K. (2015) · The journal of nutrition health & aging · doi:10.1007/s12603-015-0463-6 · Cited by 12
Cardiorespiratory Fitness, Inflammation, and Risk of Chronic Obstructive Pulmonary Disease in Middle-Aged Men
Kunutsor, S. K., Jae, S. Y., Mäkikallio, T. H., & Laukkanen, J. A. (2022) · Journal of Cardiopulmonary Rehabilitation and Prevention · doi:10.1097/hcr.0000000000000674 · Cited by 12
Percentage of Age-Predicted Cardiorespiratory Fitness May Be a Stronger Risk Indicator for Incident Type 2 Diabetes Than Absolute Levels of Cardiorespiratory Fitness
Kunutsor, S. K., Khan, H., Seidu, S., & Laukkanen, J. A. (2022) · Journal of Cardiopulmonary Rehabilitation and Prevention · doi:10.1097/hcr.0000000000000720 · Cited by 12
Associations of Milk Consumption and Vitamin B2 and Β12 Derived from Milk with Fitness, Anthropometric and Biochemical Indices in Children. The Healthy Growth Study
Moschonis, G., van den Heuvel, E. G. H. M., Mavrogianni, C., Singh‐Povel, C. M., Leotsinidis, M., & Μanios, Y. (2016) · Nutrients · doi:10.3390/nu8100634 · Cited by 12
Association of metabolic syndrome and level of hs-CRP, Lp(a), and serum ferritin in young Asian patients (≤45 years) with acute myocardial infarction
Ramesh, G., Sai, N. V. B., Pramod, G., Bhupal, R., & Patel, N. (2018) · Interventional Medicine and Applied Science · doi:10.1556/1646.10.2018.14 · Cited by 12

Authors: Salonen, J. T., Nyyssönen, K., Korpela, H., Tuomilehto, J., Seppänen, R., & Salonen, R.
Affiliations: University of Eastern Finland (FI)
ORCID: Korpela, H
Tuomilehto, J
Venue: Circulation
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 1992-09
Volume: 86
Issue: 3
Pages: 803-811
ISSN: 0009-7322 (ISSN-L)
1524-4539
DOI: 10.1161/01.cir.86.3.803
OpenAlex: W2065303599
Cited by: 1,284
References: 38
Citations by year: 2026: 8 · 2025: 15 · 2024: 16 · 2023: 17 · 2022: 43 · 2021: 32 · 2020: 27 · 2019: 33 · 2018: 36 · 2017: 42 · 2016: 47 · 2015: 35 · 2014: 38 · 2013: 40 · 2012: 48
FWCI: 34.96
Type: journal article
Language: en
Open access: closed
Locations: Circulation (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Hematology › Iron Metabolism and Disorders
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Acute Myocardial Infarction Research
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
Keywords: serum ferritin, stored iron, acute myocardial infarction, coronary heart disease risk, iron intake, lipid peroxidation, LDL cholesterol, men, Eastern Finland
MeSH terms: Adult, Aging, Diet, Dose-Response Relationship, Drug, Ferritins, Finland, Hemoglobins, Humans, Iron, Cholesterol, LDL, Male, Middle Aged, Myocardial Infarction, Risk Factors, Smoking, Proportional Hazards Models

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

High stored iron levels are associated with excess risk of myocardial infarction in eastern Finnish men

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks