CoChat
Sign Up
Cited by 259Cardiovascular Function and Risk FactorsBlood Pressure and Hypertension StudiesCardiovascular Effects of Exercise

The DOI matches its Crossref record; 34 of the 36 references it cites were found in a registry or an index.

Effect of Body Size, Ponderosity, and Blood Pressure on Left Ventricular Growth in Children and Young Adults in the Bogalusa Heart Study

Urbina, Elaine M., Gidding, Samuel S., Bao, Weihang, Pickoff, Arthur S., Berdusis, Kaliope, Berenson, Gerald S.·1995·Circulation
DOI 10.1161/01.cir.91.9.2400
Open this paper in CoChat — free account

Abstract

Background The measurement of left ventricular mass (LVM) is important because individuals with increased LVM are at increased risk for cardiovascular diseases, including myocardial infarction and congestive heart failure. There are limited longitudinal data on the acquisition of LVM in children and young adults and the relative importance of sex, growth, excess body weight, and blood pressure (BP) on change in LVM. Methods and Results The study cohort consisted of a cross section of 160 healthy children and young adults 9 to 22 years of age at first exam in the biracial community of Bogalusa, La. All had stable BP levels recorded over a 2- to 3-year period. Repeated examinations were performed 4 to 5 years apart. At each exam, 6 BPs were obtained with a mercury sphygmomanometer by trained examiners. The mean of the observations was used, with the fourth Korotkoff phase serving as the measure of diastolic BP. Anthropometric data, including height (HT), weight (WT), and triceps skin fold thickness (TSF), were also obtained, and M-mode echocardiograms were performed. Ponderal index (PI=WT/HT 3 ) was used as a measure of weight-for-height. Tracking of HT ( r =.68 to .76), WT ( r =.73 to .82), PI ( r =.77 to .89), TSF ( r =.70 to .80), BP ( r =.47 to .60), and LVM ( r =.40 to .70) was strong in both sexes ( P <.0001). LVM indexed for linear growth (LVM/HT 2.7 ) tracked in females ( r =.56, P <.0001) but not in males. In univariate cross-sectional analyses, LVM/HT 2.7 correlated with WT, PI, and TSF in both sexes ( r =.21 to .60, P <.05) and with systolic BP (SBP) in females ( r =.23, P <.05). WT was the only independent correlate of LVM/HT 2.7 in both sexes in multivariate cross-sectional analysis in a model containing age, SBP, WT, and TSF as independent variables ( r 2 =.08 to .28, P <.02). In longitudinal univariate analyses, initial measurements of WT, PI, and TSF predicted final LVM/HT 2.7 in both sexes ( r =.28 to .56, P <.01), and SBP was significant for females ( r =.27, P <.05). In multivariate analyses, initial WT was associated with final LVM and LVM/HT 2.7 in both sexes ( r 2 =.27 to .54, P <.01). Finally, baseline LVM correlated with final SBP in both sexes ( r =.21 to .27, P <.05), and initial LVM/HT 2.7 correlated with final SBP in females ( r =.26, P <.05) with a trend for males ( r =.17). Conclusions These data indicate that linear growth is the major determinant of cardiac growth in children and that excess weight may lead to the acquisition of LVM beyond that expected from normal growth. Increased mass may also precede the development of increased BP. The development of obesity may therefore be a significant, and possibly modifiable, risk factor for developing left ventricular hypertrophy and hypertension, risk factors for cardiovascular morbidity and mortality.

Overview

Integrity signals

Registry

Crossref · 10.1161/01.cir.91.9.2400

Cites

34 of 34 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Show all 36 references

Research works printed but not linked: 6

  1. 10.1161/circ.59.4.154367 · DOI
  2. 10.1161/circ.62.5.7418156 · DOI
  3. Morales MC, Gleim GW, Marino ND, Stachenfeld NS, Coplan NL. Left ventricular mass in adolescent basketball players. Cardiovasc Rev Reports. 1992;13:60-62.
  4. 10.1161/circ.75.1.2947739 · DOI
  5. 10.1161/circ.85.5.1572024 · DOI
  6. 10.1161/circ.67.5.6219830 · DOI

Cited by

Sorted by citations

See all 259

Related

Metadata

Authors
Urbina, E. M., Gidding, S. S., Bao, W., Pickoff, A. S., Berdusis, K., & Berenson, G. S.
Affiliations
Tulane University (US)
ORCID
Venue
Circulation
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
1995-05
Volume
91
Issue
9
Pages
2400-2406
ISSN
  • 0009-7322 (ISSN-L)
  • 1524-4539
DOI
10.1161/01.cir.91.9.2400
OpenAlex
W2159829699
Cited by
259
References
36
Citations by year
2025: 3 · 2024: 2 · 2023: 3 · 2022: 7 · 2021: 6 · 2020: 13 · 2019: 5 · 2018: 14 · 2017: 12 · 2016: 6 · 2015: 8 · 2014: 11 · 2013: 19 · 2012: 8
FWCI
7.80
Type
journal article
Language
en
Open access
closed
Locations
  • Circulation (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Health (2r01hl038844-06)
  • National Heart, Lung, and Blood Institute (5R01-HL38844)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Effects of Exercise
Keywords
left ventricular mass, left ventricular hypertrophy, body size, ponderal index, blood pressure, childhood obesity, weight gain, triceps skinfold thickness, sex differences, linear growth, children and young adults, Bogalusa Heart Study, cardiovascular risk, echocardiography, systolic blood pressure, diastolic blood pressure, anthropometry
MeSH terms
Adolescent, Adult, Blood Pressure, Body Constitution, Body Weight, Child, Female, Follow-Up Studies, Heart Diseases, Heart Ventricles, Humans, Louisiana, Male, Risk Factors, Cohort Studies

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review