Severe Obesity in Children and Adolescents: Identification, Associated Health Risks, and Treatment Approaches: A Scientific Statement From the American Heart Association
Abstract
Severe obesity afflicts between 4% and 6% of all youth in the United States, and the prevalence is increasing. Despite the serious immediate and long-term cardiovascular, metabolic, and other health consequences of severe pediatric obesity, current treatments are limited in effectiveness and lack widespread availability. Lifestyle modification/behavior-based treatment interventions in youth with severe obesity have demonstrated modest improvement in body mass index status, but participants have generally remained severely obese and often regained weight after the conclusion of the treatment programs. The role of medical management is minimal, because only 1 medication is currently approved for the treatment of obesity in adolescents. Bariatric surgery has generally been effective in reducing body mass index and improving cardiovascular and metabolic risk factors; however, reports of long-term outcomes are few, many youth with severe obesity do not qualify for surgery, and access is limited by lack of insurance coverage. To begin to address these challenges, the purposes of this scientific statement are to (1) provide justification for and recommend a standardized definition of severe obesity in children and adolescents; (2) raise awareness of this serious and growing problem by summarizing the current literature in this area in terms of the epidemiology and trends, associated health risks (immediate and long-term), and challenges and shortcomings of currently available treatment options; and (3) highlight areas in need of future research. Innovative behavior-based treatment, minimally invasive procedures, and medications currently under development all need to be evaluated for their efficacy and safety in this group of patients with high medical and psychosocial risks.
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NHANES is representative of the US civilian, noninstitutionalized population.
“A nationally representative survey of the civilian, noninstitutionalized population, the National Health and Nutrition Examination Survey (NHANES) contains both interviews and examinations.14”
From Differences in Obesity Prevalence by Demographics and Urbanization in US Children and Adolescents, 2013-2016 (2018) · cites this paper as [14]
School-aged children and adolescents who have high BMIs and excessive body weights are known to be at high risk of developing cardiovascular, metabolic and musculoskeletal diseases.
“school-aged children and adolescents who have high BMIs and excessive body weights are known to be at high risk of developing other health problems, including cardiovascular, metabolic and musculoskeletal diseases,25”
From Physical activity and health in Chinese children and adolescents: expert consensus statement (2020) (2020) · cites this paper as [25]
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Viner, R., Hsia, Y., Tomsic, T., & Wong, I. C. K. (2009) · Obesity Reviews · doi:10.1111/j.1467-789x.2009.00651.x · Cited by 107 · see citing works
Bariatric Surgery in Adolescence. Is this the Best Age to Operate?
Capella, J. F., & Capella, R. F. (2003) · Obesity Surgery · doi:10.1381/096089203322618597 · Cited by 104 · see citing works
Two-year trends in psychosocial functioning after adolescent Roux-en-Y gastric bypass
Zeller, M. H., Reiter‐Purtill, J., Ratcliff, M. B., Inge, T. H., & Noll, J. G. (2011) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2011.01.034 · Cited by 104 · see citing works
Self-citationLawlor, D. A., Martin, R. M., Gunnell, D., Galobardes, B., Ebrahim, S. B. J., Sandhu, J., Ben‐Shlomo, Y., McCarron, P., & Smith, G. D. (2006) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/83.4.767 · Cited by 103 · see citing works
Rademacher, E. R., Jacobs, D. R., Moran, A., Steinberger, J., Prineas, R. J., & Sinaiko, A. (2009) · Journal of Hypertension · doi:10.1097/hjh.0b013e32832e8cfa · Cited by 101 · see citing works
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Nutritional consequences of bariatric surgery
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Obesity in youth is not an independent predictor of carotid IMT in adulthood
Juonala, M., Raitakari, M., Viikari, J. S. A., & Raitakari, O. T. (2005) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2005.06.016 · Cited by 97 · see citing works
Gidding, S. S., Nehgme, R., Heise, C. T., et al. (2004) · The Journal of Pediatrics · doi:10.1016/s0022-3476(04)00243-4 · Cited by 97 · see citing works
Kohler, M. J., Thormaehlen, S., Kennedy, J. D., Pamula, Y., van den Heuvel, C. J., Lushington, K., & Martin, A. (2009) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.27649 · Cited by 96 · see citing works
Schlaud, M., Urschitz, M. S., Urschitz‐Duprat, P. M., & Poets, C. F. (2004) · Paediatric and Perinatal Epidemiology · doi:10.1111/j.1365-3016.2004.00589.x · Cited by 96 · see citing works
Daniels, S. R., Witt, S. A., Glascock, B. J., Khoury, P. R., & Kimball, T. R. (2002) · The Journal of Pediatrics · doi:10.1067/mpd.2002.125851 · Cited by 95 · see citing works
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PRATT, C. A., Stevens, J., & Daniels, S. R. (2008) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2008.05.025 · Cited by 94 · see citing works
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Crowley, D. I., Khoury, P. R., Urbina, E. M., Ippisch, H. M., & Kimball, T. R. (2011) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2010.10.016 · Cited by 92 · see citing works
Self-citationPredicting Heart Growth During Puberty: The Muscatine Study
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Burgert, T. S., Duran, E. J., Goldberg-Gell, R., Dziura, J. D., Yeckel, C. W., Katz, S. D., Tamborlane, W. V., & Caprio, S. (2008) · Pediatric Diabetes · doi:10.1111/j.1399-5448.2008.00434.x · Cited by 90 · see citing works
Till, H., Blüher, S., Hirsch, W., et al. (2008) · Obesity Surgery · doi:10.1007/s11695-008-9543-6 · Cited by 89 · see citing works
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Ogden, C. L., Carroll, M. D., Lawman, H. G., Fryar, C. D., Kruszon-Moran, D., Kit, B. K., & Flegal, K. M. (2016) · JAMA · doi:10.1001/jama.2016.6361 · Cited by 2,178 · see citing works
Hampl, S. E., Hassink, S. G., Skinner, A. C., Armstrong, S. C., Barlow, S. E., Bolling, C. F., Avila Edwards, K. C., Eneli, I., Hamre, R., Joseph, M. M., et al. (2023) · Pediatrics · doi:10.1542/peds.2022-060640 · Cited by 1,389 · see citing works
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Weight loss and health status 3 years after bariatric surgery in adolescents
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“…taken, will raise serious public health concerns because school-aged children and adolescents who have high BMIs and excessive body weights are known to be at high risk of developing other health problems, including cardiovascular, metabolic and musculoskeletal diseases, 25 as well as depression.”
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Varman, S. D., Cliff, D. P., Jones, R. A., Hammersley, M. L., Zhang, Z., Charlton, K., & Kelly, B. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph182010824 · Cited by 71 · see citing works
Nathan, B. M., Rudser, K. D., Abuzzahab, M. J., Fox, C. K., Coombes, B. J., Bomberg, E. M., & Kelly, A. S. (2016) · Clinical Obesity · doi:10.1111/cob.12128 · Cited by 39 · see citing works
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- Authors
- Kelly, A. S., Barlow, S. E., Rao, G., Inge, T. H., Hayman, L. L., Steinberger, J., Urbina, E. M., Ewing, L. J., & Daniels, S. R.
- ORCID
- Venue
- Circulation
- Published
- 2013-10-08
- Volume
- 128
- Issue
- 15
- Pages
- 1689-1712
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2111740150
- Cited by
- 980
- References
- 273
- Citations by year
- 2026: 32 · 2025: 38 · 2024: 55 · 2023: 72 · 2022: 83 · 2021: 92 · 2020: 105 · 2019: 93 · 2018: 98 · 2017: 100 · 2016: 86 · 2015: 71 · 2014: 49 · 2013: 4 · 2012: 1
- FWCI
- 71.40
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Circulation (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (UL1TR000077)
- National Center for Advancing Translational Sciences
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
- Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
- Health Sciences › Health Professions › Pharmacy › Obesity and Health Practices
- Keywords
- childhood obesity, adolescent obesity, obesity prevalence trends, cardiovascular risk, metabolic risk, obesity treatment, bariatric surgery, anti-obesity drugs, lifestyle modification, weight regain, minimally invasive procedures, psychosocial risks
- MeSH terms
- Adolescent, American Heart Association, Child, Humans, Obesity, Morbid, Risk Factors, United States
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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