The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
Childhood Uric Acid Predicts Adult Blood Pressure: The Bogalusa Heart Study
Open accessAbstract
Uric acid has been proposed as an important risk factor in the development of primary hypertension in humans. However, limited information is available linking childhood uric acid levels and blood pressure levels in adulthood. This study examined 334 whites and 243 blacks enrolled in the Bogalusa Heart Study as children aged 5 to 17 years and as adults aged 18 to 35 years. The average follow-up period was 12 years. Childhood uric acid was significantly correlated with childhood and adult blood pressure, both systolic and diastolic. In a multivariate regression analysis, adjusting for age, sex, race, childhood body mass index, childhood uric acid levels, and change in levels of uric acid were significant predictors of adult diastolic blood pressure, whereas change in uric acid was a significant predictor of adult systolic blood pressures. In conclusion, elevated childhood serum uric acid levels are associated with increased blood pressure beginning in childhood and higher blood pressure levels that persist into adulthood, in males and females, whites and blacks, suggesting that early elevations in serum uric acid levels may play a key role in the development of human hypertension.
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Cites
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Serum Uric Acid and Cardiovascular Mortality: The NHANES I Epidemiologic Follow-up Study, 1971-1992
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Elevated Uric Acid Increases Blood Pressure in the Rat by a Novel Crystal-Independent Mechanism
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Hyperuricemia in Primary and Renal Hypertension
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Cited by
Flynn, J. T., Kaelber, D. C., Baker-Smith, C. M., Blowey, D., Carroll, A. E., Daniels, S. R., de Ferranti, S. D., Dionne, J. M., Falkner, B., Flinn, S. K., et al. (2017) · Pediatrics · doi:10.1542/peds.2017-1904 · Cited by 3,651
Johnson, R. J., Segal, M. S., Sautin, Y., Nakagawa, T., Feig, D. I., Kang, D.-H., Gersch, M. S., Benner, S., & Sánchez-Lozada, L. G. (2007) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/86.4.899 · Cited by 1,075
Feig, D. I., Soletsky, B., & Johnson, R. J. (2008) · JAMA · doi:10.1001/jama.300.8.924 · Cited by 914
Uric Acid Reduction Rectifies Prehypertension in Obese Adolescents
Soletsky, B., & Feig, D. I. (2012) · Hypertension · doi:10.1161/hypertensionaha.112.196980 · Cited by 334
Physiology of Hyperuricemia and Urate-Lowering Treatments
Benn, C. L., Dua, P., Gurrell, R., Loudon, P., Pike, A., Storer, R. I., & Vangjeli, C. (2018) · Frontiers in Medicine · doi:10.3389/fmed.2018.00160 · Cited by 319
Metadata
- Authors
- Alper, A. B., Chen, W., Yau, L., Srinivasan, S. R., Berenson, G. S., & Hamm, L. L.
- Venue
- Hypertension
- Published
- 2005-01
- Volume
- 45
- Issue
- 1
- Pages
- 34-38
- ISSN
- 0194-911X (ISSN-L)
- 1524-4563
- OpenAlex
- W1965503220
- Cited by
- 314
- References
- 24
- FWCI
- 8.17
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Alper, A. B., Chen, W., Yau, L., Srinivasan, S. R., Berenson, G. S., & Hamm, L. L. (2005). Childhood Uric Acid Predicts Adult Blood Pressure: The Bogalusa Heart Study. Hypertension. https://doi.org/10.1161/01.hyp.0000150783.79172.bb
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