NAD(P)H Oxidase 4 Mediates Transforming Growth Factor-β1–Induced Differentiation of Cardiac Fibroblasts Into Myofibroblasts

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Wound Healing Promoting Activity of Tonsil-Derived Stem Cells on 5-Fluorouracil-Induced Oral Mucositis Model

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Effect of melatonin on oxidative stress indicators in animal models of fibrosis: A systematic review and meta-analysis

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A Synthetic Peptide from Transforming Growth Factor-β 1 Type III Receptor Inhibits NADPH Oxidase and Prevents Oxidative Stress in the Kidney of Spontaneously Hypertensive Rats

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Can heart function lost to disease be regenerated by therapeutic targeting of cardiac scar tissue?

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Dysregulation of Alveolar Macrophage PPARγ, NADPH Oxidases, and TGFβ 1 in Otherwise Healthy HIV-Infected Individuals

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Endothelial NADPH Oxidase 4 Protects Against Angiotensin II-Induced Cardiac Fibrosis and Inflammation

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Cardiac pathologies in relation to Smad-dependent pathways

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Immune response gene 1 deficiency impairs Nrf2 activation and aggravates liver fibrosis in mice

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Cellular heterogeneity and plasticity during NAFLD progression

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The role of fibrosis in the pathophysiology of muscular dystrophy

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ROS directly activates transforming growth factor β type 1 receptor signalling in human vascular smooth muscle cells

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Temporal expression of hypoxia-regulated genes is associated with early changes in redox status in irradiated lung

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NOX4 Mediates Epithelial Cell Death in Hyperoxic Acute Lung Injury Through Mitochondrial Reactive Oxygen Species

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Molecular mechanisms and potential interventions during aging-associated sarcopenia

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Preventive and chronic mineralocorticoid receptor antagonism is highly beneficial in obese SHHF rats

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Young Bone Marrow Sca-1 Cells Rejuvenate the Aged Heart by Promoting Epithelial-to-Mesenchymal Transition

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The miRNA-184 drives renal fibrosis by targeting HIF1AN in vitro and in vivo

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An essential role of NAD(P)H oxidase 2 in UVA-induced calcium oscillations in mast cells

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Administration of apo A-I (Milano) nanoparticles reverses pathological remodelling, cardiac dysfunction, and heart failure in a murine model of HFpEF associated with hypertension

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NOX4 regulates macrophage apoptosis resistance to induce fibrotic progression

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Fulvene-5 inhibition of Nadph oxidases attenuates activation of epithelial sodium channels in A6 distal nephron cells

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Nox 4 Regulation of Vascular Smooth Muscle Cell Differentiation Marker Gene Expression

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Strategies Aimed at Nox4 Oxidase Inhibition Employing Peptides from Nox4 B‐Loop and C‐Terminus and p22 phox N‐Terminus: An Elusive Target

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NADPH oxidase 4 attenuates cerebral artery changes during the progression of Marfan syndrome

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Flavonoid-rich Scabiosa comosa inflorescence extract attenuates CCl4-induced hepatic fibrosis by modulating TGF-β-induced Smad3 phosphorylation

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The myofibroblast in connective tissue repair and regeneration

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A porcine placental extract prevents steatohepatitis by suppressing activation of macrophages and stellate cells in mice

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Effects of the (Pro)renin Receptor on Cardiac Remodeling and Function in a Rat Alcoholic Cardiomyopathy Model via the PRR-ERK1/2-NOX4 Pathway

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Renal Carcinogenesis, Tumor Heterogeneity, and Reactive Oxygen Species: Tactics Evolved

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Characterisation of Nox4 Inhibitors from Edible Plants

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SGK1 is necessary to FoxO3a negative regulation, oxidative stress and cardiac fibroblast activation induced by TGF-β1

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Pentaerythritol Tetranitrate Targeting Myocardial Reactive Oxygen Species Production Improves Left Ventricular Remodeling and Function in Rats With Ischemic Heart Failure

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Isolation and culture of adult murine cardiac atrial and ventricular fibroblasts and myofibroblasts

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High-Mobility Group A1 Promotes Cardiac Fibrosis by Upregulating FOXO1 in Fibroblasts

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Resveratrol-Mediated Expression of KLF15 in the Ischemic Myocardium is Associated with an Improved Cardiac Phenotype

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Inducible Knockdown of Endothelial Protein Tyrosine Phosphatase-1B Promotes Neointima Formation in Obese Mice by Enhancing Endothelial Senescence

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mRNA therapy for myocardial infarction: A review of targets and delivery vehicles

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Beyond TGFβ – Novel ways to target airway and parenchymal fibrosis

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NADPH Oxidase 4 Mediates TGFβ1-induced CCN2 in Gingival Fibroblasts

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Redox State in Atrial Fibrillation Pathogenesis and Relevant Therapeutic Approaches

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A novel caffeic acid derivative prevents angiotensin II-induced cardiac remodeling

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Implications of TGFβ on Transcriptome and Cellular Biofunctions of Palatal Mesenchyme

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Non-Invasive Local Acoustic Therapy Ameliorates Diabetic Heart Fibrosis by Suppressing ACE-Mediated Oxidative Stress and Inflammation in Cardiac Fibroblasts

Weng, L., Lu, L., Zhao, K., Xu, T., Mao, Y., Shu, H., Chen, X., Chen, J., Wu, J. H., Guo, X., et al. (2022) · Cardiovascular Drugs and Therapy · doi:10.1007/s10557-021-07297-6 · Cited by 14

Targeting Wnt Signaling to Improve Wound Healing After Myocardial Infarction

Daskalopoulos, E. P., Janssen, B. J., & Blankesteijn, W. M. (2013) · Methods in molecular biology · doi:10.1007/978-1-62703-505-7_21 · Cited by 15

Ganoderma Lucidum Polysaccharide Peptide attenuates post myocardial infarction fibrosis via down-regulating TGF-β1/SMAD and relieving oxidative stress

Meng, J., Ma, A., Zhang, S., Lin, D., Lin, S., Li, M., Zhou, H. Y., & Yang, B. (2022) · Pharmacological Research - Modern Chinese Medicine · doi:10.1016/j.prmcm.2022.100152 · Cited by 16

Tacrolimus Increases Nox4 Expression in Human Renal Fibroblasts and Induces Fibrosis-Related Genes by Aberrant TGF-Beta Receptor Signalling

Kern, G., Mair, S., Noppert, S.-J., Jennings, P., Schramek, H., Rudnicki, M., Muller, G. A., Mayer, G. J., & Koppelstaetter, C. (2014) · PLoS ONE · doi:10.1371/journal.pone.0096377 · Cited by 14

Redox-sensitive mechanisms underlying vascular dysfunction in heart failure

Konradi, J., Mollenhauer, M., Baldus, S. E., & Klinke, A. (2015) · Free Radical Research · doi:10.3109/10715762.2015.1027200 · Cited by 14

Relationships Between Vascular Oxygen Sensing Mechanisms and Hypertensive Disease Processes

Gupte, S. A., & Wolin, M. S. (2012) · Hypertension · doi:10.1161/hypertensionaha.112.190702 · Cited by 14

Left Ventricular SGLT1 Protein Expression Correlates with the Extent of Myocardial Nitro-Oxidative Stress in Rats with Pressure and Volume Overload-Induced Heart Failure

Sayour, A. A., Ruppert, M., Oláh, A., Benke, K., Barta, B. A., Zsáry, E., Ke, H., Horvath, E. M., Merkely, B. P., & Radovits, T. (2021) · Antioxidants · doi:10.3390/antiox10081190 · Cited by 14

Combination release of chemokines from coated coils to target aneurysm healing

Laurent, D., Lucke-Wold, B. P., Dodd, W., Martinez, M., Chowdhury, M. A. B., Hosaka, K., Motwani, K., & Hoh, B. L. (2022) · Journal of NeuroInterventional Surgery · doi:10.1136/neurintsurg-2022-018710 · Cited by 13

Androgen modulates cardiac fibrosis contributing to gender differences on heart failure

Chung, C., Kao, Y., Chen, Y., & Chen, Y.-J. (2013) · The Aging Male · doi:10.3109/13685538.2012.754008 · Cited by 13

TGFβ1 suppresses vascular smooth muscle cell motility by expression of N-cadherin

Nüßle, J. M., Giehl, K., Herzog, R., Stracke, S., & Menke, A. (2011) · Biological Chemistry · doi:10.1515/bc.2011.053 · Cited by 13

Reducing Cardiac Fibrosis: Na/K-ATPase Signaling Complex as a Novel Target

Fan, X., Xie, J., & Tian, J. (2017) · Cardiovascular Pharmacology Open Access · doi:10.4172/2329-6607.1000204 · Cited by 12

Sodium tanshinone IIA sulfonate attenuates the transforming growth factor-β1-induced differentiation of atrial fibroblasts into myofibroblasts in vitro

Yang, L., Hu, J., Hao, H.-Z., YIN, Z., Liu, G., & Zou, X. (2015) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2015.2087 · Cited by 13

Extracellular superoxide dismutase inhibits hepatocyte growth factor-mediated breast cancer-fibroblast interactions

Ormsbee, B. D., Griess, B., Mir, S. U. R., Fitzgerald, M. P., Kuperwasser, C., Domann, F. E., & Teoh-Fitzgerald, M. L. T. (2017) · Oncotarget · doi:10.18632/oncotarget.22379 · Cited by 13

The TβR II-targeted aptamer S58 prevents fibrosis after glaucoma filtration surgery

Li, X., Leng, Y., Li, X., Wang, Y., Luo, P., Zhang, C., Wang, Z., Yue, X., Shen, C., Chen, L., et al. (2020) · Aging · doi:10.18632/aging.102997 · Cited by 12

Polarization of human gingival fibroblasts by Th1‐, Th2‐, Th17‐, and Treg‐derived cytokines

Ha, D., Jung, J., Choi, G. H., & Ji, S. (2022) · Journal of Periodontal Research · doi:10.1111/jre.12978 · Cited by 12

NADPH oxidase 4 expression in the normal endometrium and in endometrial cancer

Degasper, C., Brunner, A., Sampson, N., Tsibulak, I., Wieser, V. E., Welponer, H., Marth, C., Fiegl, H., & Zeimet, A. G. (2019) · Tumor Biology · doi:10.1177/1010428319830002 · Cited by 12

The hydrogen-peroxide producing NADPH oxidase 4 does not limit neointima development after vascular injury in mice

Buchmann, G., Schürmann, C., Spaeth, M., Abplanalp, W. T., Tombor, L. S., John, D., Warwick, T., Rezende, F., Weigert, A., Shah, A. M., et al. (2021) · Redox Biology · doi:10.1016/j.redox.2021.102050 · Cited by 12

Pathophysiologie und Therapie der benignen Prostata-Hyperplasie

Sampson, N., Stephan Madersbacher, A., & Berger, P. (2008) · Wiener klinische Wochenschrift · doi:10.1007/s00508-008-0986-5 · Cited by 12

Redox Mechanisms Driving Skin Fibroblast-to-Myofibroblast Differentiation

Aminzadehanboohi, M., Makridakis, M., Rasti, D., Cambet, Y., Krause, K., Vlahou, A., & Jaquet, V. (2025) · Antioxidants · doi:10.3390/antiox14040486 · Cited by 11

Nanocatalytic antioxidation synergizes cardioprotection and antifibrosis in cardiac injury

He, R., Yang, B., & Shi, J. (2025) · Nano Today · doi:10.1016/j.nantod.2025.102820 · Cited by 10

Hopes and Hurdles of Employing Mesenchymal Stromal Cells in the Treatment of Cardiac Fibrosis

Neuber, S., Emmert, M. Y., & Nazari‐Shafti, T. Z. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222313000 · Cited by 11

Polysulfide nanoparticles inhibit fibroblast-to-myofibroblast transition via extracellular ROS scavenging and have potential anti-fibrotic properties

Siani, A., Infante-Teixeira, L., d’Arcy, R., Roberts, I. V., Mohtadi, F. E., Donno, R., & Tirelli, N. (2023) · Biomaterials Advances · doi:10.1016/j.bioadv.2023.213537 · Cited by 12

Transforming growth factor-β1 mediates NADPH oxidase 4: A significant contributor to the pathogenesis of myocardial fibrosis

Yu, Q.-G., & Zhang, Y. (2016) · International Journal of Cardiology · doi:10.1016/j.ijcard.2016.10.118 · Cited by 4

Effect of NOX4 on the differentiation of mice cardiac fibroblasts to myofibroblasts

Wang, Y. (2010) · Journal of Clinical Cardiology

NAD(P)H Oxidase Mediates TGF-β1–Induced Activation of Kidney Myofibroblasts

Bondi, C. D., Manickam, N., Lee, D. Y., Block, K., Gorin, Y., Abboud, H. E., & Barnes, J. L. (2010) · Journal of the American Society of Nephrology · doi:10.1681/asn.2009020146 · Cited by 297

TGF-β1 stimulates HDAC4 nucleus-to-cytoplasm translocation and NADPH oxidase 4-derived reactive oxygen species in normal human lung fibroblasts

Guo, W., Saito, S., Sánchez, C. G., Zhuang, Y., Rosero, R. E. G., Shan, B., Luo, F., & Lasky, J. A. (2017) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00256.2016 · Cited by 32

Abstract 4143958: NADPH oxidase-4 is an early driver of cardiac myofibroblast differentiation and cellular senescence in dilated cardiomyopathy

Berhanu, S., Antolic, A. T., Shin, Y. J., Kato, K., Kleinhenz, J., Jiao, Z., Hecker, L., & Burke, M. A. (2024) · Circulation · doi:10.1161/circ.150.suppl_1.4143958