The DOI matches its Crossref record; 49 of the 49 references it cites were found in a registry or an index.
Abdominal Obesity and Risk of Ischemic Stroke: The Northern Manhattan Stroke Study
Abstract
Background and Purpose— Obesity is well recognized as a risk factor for coronary heart disease and mortality. The relationship between abdominal obesity and ischemic stroke remains less clear. Our aim was to evaluate abdominal obesity as an independent risk factor for ischemic stroke in a multiethnic community. Methods— A population-based, incident case-control study was conducted July 1993 through June 1997 in northern Manhattan, New York, NY. Cases (n=576) of first ischemic stroke (66% ≥65 years of age; 56% women; 17% whites; 26% blacks; 55% Hispanics) were enrolled and matched by age, sex, and race-ethnicity to stroke-free community controls (n=1142). All subjects were interviewed and examined and had measurements of waist-to-hip ratio (WHR). Odds ratios (ORs) of ischemic stroke were calculated with gender-specific quartiles (GQs) and gender-specific medians of WHR adjusted for stroke risk factors and body mass index (BMI). Results— Compared with the first quartile, the third and fourth quartiles of WHR had an increased risk of stroke (GQ3: OR, 2.4; 95% CI, 1.5 to 3.9; GQ4: OR, 3.0; 95% CI, 1.8 to 4.8) adjusted for other risk factors and BMI. Those with WHR equal to or greater than the median had an overall OR of 3.0 (95% CI, 2.1 to 4.2) for ischemic stroke even after adjustment for other risk factors and BMI. Increased WHR was associated with a greater risk of stroke in men and women and in all race-ethnic groups. The effect of WHR was stronger among younger persons (test for heterogeneity, P <0.0002) (<65 years of age: OR, 4.4; 95%CI, 2.2 to 9.0; ≥65 years of age: OR, 2.2; 95% CI, 1.4 to 3.2). WHR was associated with an increased risk among those with and without large-artery atherosclerotic stroke. Conclusions— Abdominal obesity is an independent, potent risk factor for ischemic stroke in all race-ethnic groups. It is a stronger risk factor than BMI and has a greater effect among younger persons. Prevention of obesity and weight reduction need greater emphasis in stroke prevention programs.
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“The pattern of obesity also may influence stroke risk.”
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“Several studies highlight the relationship between obesity and risk of stroke.”
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“Individuals with a waist-to-hip ratio equal to or greater than the median had an overall odds ratio (OR) of 3.0 (95% CI, 2.1 to 4.2) for ischemic stroke even after adjustment for other risk factors and BMI.”
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Citations
Cites
(1998) · PsycEXTRA Dataset · doi:10.1037/e565682010-001 · Cited by 9,453
The Disease Burden Associated With Overweight and Obesity
Must, A. (1999) · JAMA · doi:10.1001/jama.282.16.1523 · Cited by 4,827
Hubert, H. B., Feinleib, M., McNamara, P. M., & Castelli, W. P. (1983) · Circulation · doi:10.1161/01.cir.67.5.968 · Cited by 4,241
Body-Mass Index and Mortality in a Prospective Cohort of U.S. Adults
Calle, E. E., Thun, M. J., Petrelli, J. M., Rodriguez, C., & Heath, C. W. (1999) · New England Journal of Medicine · doi:10.1056/nejm199910073411501 · Cited by 3,643
Overweight and obesity in the United States: prevalence and trends, 1960–1994
Flegal, K., Carroll, M., Kuczmarski, R., & Johnson, C. (1998) · International Journal of Obesity · doi:10.1038/sj.ijo.0800541 · Cited by 3,045
The Spread of the Obesity Epidemic in the United States, 1991-1998
Mokdad, A. H. (1999) · JAMA · doi:10.1001/jama.282.16.1519 · Cited by 2,384
Larsson, B., Svärdsudd, K., Welin, L., Wilhelmsen, L., Björntorp, P. A., & Tibblin, G. (1984) · BMJ · doi:10.1136/bmj.288.6428.1401 · Cited by 1,931
Lapidus, L., Bengtsson, C., Larsson, B., Pennert, K. M., Rybo, E., & Sjöström, L. (1984) · BMJ · doi:10.1136/bmj.289.6454.1257 · Cited by 1,657
The Degree of Masculine Differentiation of Obesities
Vague, J. (1956) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/4.1.20 · Cited by 1,393
The spread of the obesity epidemic in the United States
Mokdad, A. H., Serdula, M. K., & Dietz, W. H. (1999) · Cited by 985
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Items 401–419 of 419
Xu, Y., Li, Z., Wu, S.-Y., & Zhu, X.-M. (2026) · BMC Cardiovascular Disorders · doi:10.1186/s12872-026-05711-1
Deng, T., Wu, G., Liang, X., Peng, Y., Dong, Z., Shen, Y. C., & Qin, Y. (2026) · Reviews in Cardiovascular Medicine · doi:10.31083/rcm45989
“In terms of gender differences, the global stroke incidence is 33% greater in males than in females, and abdominal obesity is more common in males, significantly increasing stroke risk even among individuals with a normal weight [49,50].”
Raujol, J. (2016) · theses.fr (ABES) · doi:10.70675/c3edfb95z0530z4ed1zbe1cz85eb4ecfda4d
Han, Z., Li, Y., & Zou, H. (2026) · Life · doi:10.3390/life16040666
“By 2030, the number of ischaemic stroke-related deaths is projected to increase to 4.9 million [10–13].”
InfluentialBidirectional relationship between metabolic and thrombotic disease mechanisms
Jameson, A. T., & Hur, W. S. (2026) · Current Opinion in Hematology · doi:10.1097/moh.0000000000000929
Huang, L., Ping, C., Ming, Y., Lei, X., & Li, L. (2026) · Neuroepidemiology · doi:10.1159/000553092
Guo, H., Xiao, F., Cheng, Z., Wang, L., & Rao, Q. (2026) · Experimental Gerontology · doi:10.1016/j.exger.2026.113317
Heart and Brain: Linking Obesity-Related Inflammation, Cardiovascular Disease and Cognitive Function
Reiss, A. B., Gulkarov, S., Syed, U., Ben-Dor, G. A., Srivastava, A., Singh, M., & Leon, J. D. (2026) · Journal of Cardiovascular Development and Disease · doi:10.3390/jcdd13100477
“The link between obesity and elevated stroke risk is driven by comorbidities such as hypercholesterolemia, hypertension, and diabetes mellitus [117–119].”
Chemokine CXCL10 and Incident Stroke Risk in the Northern Manhattan Study
Shahrestani, M. N., Agudelo, C., Gardener, H. E., Veledar, E., Santiago, J. A., Tullio, M. R. D., Della‐Morte, D., Aimagambetova, B., Gutierrez, J., Hornig, M., et al. (2026) · Translational Stroke Research · doi:10.1007/s12975-026-01498-7
“At the phlebotomy visit, waist and hip circumferences were measured at the umbilicus and the greater trochanters to calculate the waist-to-hip ratio [24].”
Self-citationEffects of Metabolic Risk Factors and Type 1 Diabetes on Brain Glucose and Brain Metabolites
Heikkilä, O. (2010) · Työväentutkimus Vuosikirja
Secondary prevention of stroke following Transient Ischaemic Attack : a mixed methods study
Lager, K. E. (2013) · Leicester Research Archive (University of Leicester)
Metadata
- Authors
- Suk, S.-H., Sacco, R. L., Boden-Albala, B., Cheun, J. F., Pittman, J. G., Elkind, M. S., & Paik, M. C.
- Affiliations
- Wonkwang University (KR)
- Venue
- Stroke
- Published
- 2003-07
- Volume
- 34
- Issue
- 7
- Pages
- 1586-1592
- ISSN
- 0039-2499 (ISSN-L)
- 1524-4628
- OpenAlex
- W1972527308
- Cited by
- 420
- References
- 49
- Citations by year
- 2026: 11 · 2025: 17 · 2024: 11 · 2023: 5 · 2022: 12 · 2021: 21 · 2020: 13 · 2019: 14 · 2018: 11 · 2017: 17 · 2016: 21 · 2015: 22 · 2014: 27 · 2013: 18 · 2012: 18
- FWCI
- 13.39
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Stroke (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Wonkwang University
- National Institute of Neurological Disorders and Stroke (R01NS029993, R01-NS 29993)
- Topics
- Health Sciences › Medicine › Clinical Neurology › Acute Ischemic Stroke Management
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
- Keywords
- abdominal obesity, ischemic stroke, waist-to-hip ratio, stroke risk factors, body mass index, large artery atherosclerotic stroke, racial and ethnic differences, age differences, multi-ethnic communities, Northern Manhattan, young adults, sex differences, community control, body fat distribution, cardiovascular risk stratification, stroke prevention, stroke rehabilitation
- MeSH terms
- Abdomen, Aged, Black or African American, Body Constitution, Brain Ischemia, Demography, Female, Hispanic or Latino, Humans, Male, New York City, Obesity, Risk Factors, Comorbidity, Body Mass Index, Incidence, Odds Ratio, Case-Control Studies, Age Distribution, Sex Distribution, Stroke, Black People, White People
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