The DOI matches its Crossref record; 135 of the 135 references it cites were found in a registry or an index.
Rodent models of cerebral ischemia.
Open accessAbstract
The use of physiologically regulated, reproducible animal models is crucial to the study of ischemic brain injury--both the mechanisms governing its occurrence and potential therapeutic strategies. Several laboratory rodent species (notably rats and gerbils), which are readily available at relatively low cost, are highly suitable for the investigation of cerebral ischemia and have been widely employed for this purpose. We critically examine and summarize several rodent models of transient global ischemia, resulting in selective neuronal injury within vulnerable brain regions, and focal ischemia, typically giving rise to localized brain infarction. We explore the utility of individual models and emphasize the necessity for meticulous experimental control of those variables that modulate the severity of ischemic brain injury.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Delayed neuronal death in the gerbil hippocampus following ischemia
Kirino, T. (1982) · Brain Research · doi:10.1016/0006-8993(82)90833-2 · Cited by 2,833
Bederson, J. B., Pitts, L. H., Tsuji, M., Nishimura, M. C., Davis, R. L., & Bartkowski, H. (1986) · Stroke · doi:10.1161/01.str.17.3.472 · Cited by 2,681
Temporal profile of neuronal damage in a model of transient forebrain ischemia
Pulsinelli, W. A., Brierley, J. B., & Plum, F. (1982) · Annals of Neurology · doi:10.1002/ana.410110509 · Cited by 2,675
Glutamate and the pathophysiology of hypoxic–ischemic brain damage
Rothman, S. M., & Olney, J. W. (1986) · Annals of Neurology · doi:10.1002/ana.410190202 · Cited by 2,428
The influence of immaturity on hypoxic‐ischemic brain damage in the rat
Rice, J. E., Vannucci, R. C., & Brierley, J. B. (1981) · Annals of Neurology · doi:10.1002/ana.410090206 · Cited by 2,134
A new model of bilateral hemispheric ischemia in the unanesthetized rat.
Pulsinelli, W. A., & Brierley, J. B. (1979) · Stroke · doi:10.1161/01.str.10.3.267 · Cited by 1,934
Busto, R., Dietrich, W. D., Globus, M. Y.-T., Valdés, I., Scheinberg, P., & Ginsberg, M. D. (1987) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.1987.127 · Cited by 1,787
Self-citationTamura, A., Graham, D. I., McCulloch, J., & Teasdale, G. M. (1981) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.1981.6 · Cited by 1,425
Induction of reproducible brain infarction by photochemically initiated thrombosis
Watson, B. D., Dietrich, W. D., Busto, R., Wachtel, M. S., & Ginsberg, M. D. (1985) · Annals of Neurology · doi:10.1002/ana.410170513 · Cited by 1,135
Self-citationBusto, R., Globus, M. Y., Dietrich, W. D., Martinez, E., Valdés, I., & Ginsberg, M. D. (1989) · Stroke · doi:10.1161/01.str.20.7.904 · Cited by 1,089
Self-citation
Cited by
Ischemic Cell Death in Brain Neurons
Lipton, P. (1999) · Physiological Reviews · doi:10.1152/physrev.1999.79.4.1431 · Cited by 3,043
Calcium in Ischemic Cell Death
Kristián, T., & Siesjö, B. K. (1998) · Stroke · doi:10.1161/01.str.29.3.705 · Cited by 825
Inflammation in stroke and focal cerebral ischemia
Huang, J., Upadhyay, U. M., & Tamargo, R. J. (2006) · Surgical Neurology · doi:10.1016/j.surneu.2005.12.028 · Cited by 649
Animal models of focal and global cerebral ischemia
Traystman, R. J. (2003) · ILAR Journal · doi:10.1093/ilar.44.2.85 · Cited by 413
Middle Cerebral Artery Occlusion in Rats
Menzies, S. A., Hoff, J. T., & Betz, A. L. (1992) · Neurosurgery · doi:10.1097/00006123-199207000-00014 · Cited by 325
Metadata
- Authors
- Ginsberg, M. D., & Busto, R.
- Venue
- Stroke
- Published
- 1989-12
- Volume
- 20
- Issue
- 12
- Pages
- 1627-1642
- ISSN
- 0039-2499 (ISSN-L)
- 1524-4628
- OpenAlex
- W2125283476
- Cited by
- 659
- References
- 135
- FWCI
- 15.46
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Rodent models of cerebral ischemia. https://app.cochat.ai/papers/10.1161/01.str.20.12.1627
- The paper
- Ginsberg, M. D., & Busto, R. (1989). Rodent models of cerebral ischemia. Stroke. https://doi.org/10.1161/01.str.20.12.1627
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
