The DOI matches its Crossref record; 52 of the 52 references it cites were found in a registry or an index.
Omega-3 Polyunsaturated Fatty Acid (Fish Oil) Supplementation and the Prevention of Clinical Cardiovascular Disease: A Science Advisory From the American Heart Association
Open accessAbstract
Multiple randomized controlled trials (RCTs) have assessed the effects of supplementation with eicosapentaenoic acid plus docosahexaenoic acid (omega-3 polyunsaturated fatty acids, commonly called fish oils) on the occurrence of clinical cardiovascular diseases. Although the effects of supplementation for the primary prevention of clinical cardiovascular events in the general population have not been examined, RCTs have assessed the role of supplementation in secondary prevention among patients with diabetes mellitus and prediabetes, patients at high risk of cardiovascular disease, and those with prevalent coronary heart disease. In this scientific advisory, we take a clinical approach and focus on common indications for omega-3 polyunsaturated fatty acid supplements related to the prevention of clinical cardiovascular events. We limited the scope of our review to large RCTs of supplementation with major clinical cardiovascular disease end points; meta-analyses were considered secondarily. We discuss the features of available RCTs and provide the rationale for our recommendations. We then use existing American Heart Association criteria to assess the strength of the recommendation and the level of evidence. On the basis of our review of the cumulative evidence from RCTs designed to assess the effect of omega-3 polyunsaturated fatty acid supplementation on clinical cardiovascular events, we update prior recommendations for patients with prevalent coronary heart disease, and we offer recommendations, when data are available, for patients with other clinical indications, including patients with diabetes mellitus and prediabetes and those with high risk of cardiovascular disease, stroke, heart failure, and atrial fibrillation.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“There is a lack of evidence that OM3FA treatment reduces CV events in patients with hypertriglyceridemia of any severity, as recently reviewed by Siscovick and colleagues [8].”
From Omega-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid and their mechanisms of action on apolipoprotein B-containing lipoproteins in humans: a review (2017) · cites this paper as [8]
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“The American Heart Association scientific statements currently recommend n-3 PUFA supplements for secondary prevention of coronary heart disease 15 and in management of hypertriglyceridemia 16 .”
From Effects of n-3 Fatty Acid Supplements in Elderly Patients After Myocardial Infarction (2021) · cites this paper as [15]
In the citing paper
“However, reduction in atherosclerosis in animal models or humans by administration of OM3FAs has not been convincingly demonstrated [8, 11].”
In the citing paper
“Based on the latest meta-analysis (17) and American Heart Association Scientific Statement (18), there is modest support for their use.”
From Cardiovascular Impact of Nutritional Supplementation With Omega-3 Fatty Acids (2021) · cites this paper as [18]
In the citing paper
“Despite extensive interest and research, there is a lack of consistent support for OM-3 dietary supplements in CV risk reduction.”
From Critical Differences Between Dietary Supplement and Prescription Omega-3 Fatty Acids: A Narrative Review (2020) · cites this paper as [23]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Fish Consumption, Fish Oil, Omega-3 Fatty Acids, and Cardiovascular Disease
Kris-Etherton, P. M., Harris, W. S., & Appel, L. J. (2002) · Circulation · doi:10.1161/01.cir.0000038493.65177.94 · Cited by 3,707
Self-citationBurr, M. L., Gilbert, J. F., Holliday, R. M., Elwood, P. C., Fehily, A. M., Rogers, S., Sweetnam, P. M., & Deadman, N. M. (1989) · The Lancet · doi:10.1016/s0140-6736(89)90828-3 · Cited by 2,610
Yokoyama, M., Origasa, H., Matsuzaki, M., Matsuzawa, Y., Saito, Y., Ishikawa, Y., Oikawa, S., Sasaki, J., Hishida, H., Itakura, H., et al. (2007) · The Lancet · doi:10.1016/s0140-6736(07)60527-3 · Cited by 2,516
(1999) · PubMed · Cited by 2,062
Fish Intake, Contaminants, and Human Health: Evaluating the Risks and the Benefits
Mozaffarian, D., & Rimm, E. B. (2006) · JAMA · doi:10.1001/jama.296.15.1885 · Cited by 1,966
Self-citationTriglycerides and Cardiovascular Disease: A Scientific Statement From the American Heart Association
Miller, M., Stone, N. J., Ballantyne, C., Bittner, V., Criqui, M. H., Ginsberg, H. N., Goldberg, A. C., Howard, W. J., Jacobson, M. S., Kris-Etherton, P. M., et al. (2011) · Circulation · doi:10.1161/cir.0b013e3182160726 · Cited by 1,871
Self-citationOmega-3 Fatty Acids and Cardiovascular Disease
Mozaffarian, D., & Wu, J. H. Y. (2011) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2011.06.063 · Cited by 1,771
Self-citationGISSI-HF investigators (2008) · The Lancet · doi:10.1016/s0140-6736(08)61239-8 · Cited by 1,350
Marchioli, R., Barzi, F., Bomba, E., Chieffo, C., Di Gregorio, D., Di Mascio, R., Franzosi, M. G., Geraci, E., Levantesi, G., Maggioni, A. P., et al. (2002) · Circulation · doi:10.1161/01.cir.0000014682.14181.f2 · Cited by 1,311
Cited by
Sorted by citations
Items 301–400 of 629
The Efficacy of Anti-inflammatory Agents in the Prevention of Atrial Fibrillation Recurrences
Nomani, H., Saei, S., Johnston, T. P., Sahebkar, A., & Mohammadpour, A. H. (2020) · Current Medicinal Chemistry · doi:10.2174/1389450121666200302095103 · Cited by 15
Noce, A., Marrone, G., Daniele, F. D., Lauro, M. D., Zaitseva, A. P., Jones, G. W., LORENZO, A. D., & Daniele, N. D. (2020) · Nutrients · doi:10.3390/nu12092519 · Cited by 17
Hu, T., Sun, Y., Li, H., Du, P., Liu, L., & An, Z. (2021) · Journal of Chromatography A · doi:10.1016/j.chroma.2021.461939 · Cited by 15
Fish consumption, fish oil supplements and risk of atherosclerosis in the Tromsø study
Johnsen, S. H., Jacobsen, B. K., Brækkan, S. K., Hansen, J., & Mathiesen, E. B. (2018) · Nutrition Journal · doi:10.1186/s12937-018-0364-8 · Cited by 15
Baum, S. J., & Scholz, K. P. (2019) · Clinical Cardiology · doi:10.1002/clc.23220 · Cited by 15
Foley, S., Miller, E., Braziel, S., & Lee, S. (2020) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2020.183365 · Cited by 15
Preventing Diabetes and Atherosclerosis in the Cardiometabolic Syndrome
Ahmad, M. I., & Shapiro, M. D. (2021) · Current Atherosclerosis Reports · doi:10.1007/s11883-021-00913-8 · Cited by 14
DHA Supplementation Attenuates MI-Induced LV Matrix Remodeling and Dysfunction in Mice
Habicht, I., Mohsen, G., Eichhorn, L., Frede, S., Weisheit, C. K., Hilbert, T., Treede, H., Güresir, E., Dewald, O., Duerr, G. D., et al. (2020) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2020/7606938 · Cited by 14
Serum Oxylipin Profiles Identify Potential Biomarkers in Patients with Acute Aortic Dissection
Jiang, Y., Tang, X., Wang, Y., Chen, W., Xue, Y., Cao, H., Zhang, B., Pan, J., Zhou, Q., Wang, D., et al. (2022) · Metabolites · doi:10.3390/metabo12070587 · Cited by 14
Ma, T., He, L., Luo, Y., Zhang, G., Cheng, X., & Bai, Y. (2022) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2022.09.016 · Cited by 14
Hande, L. N., Thunhaug, H., Enebakk, T., Ludviksen, J. K., Pettersen, K., Hovland, A., & Lappegård, K. T. (2019) · Journal of clinical lipidology · doi:10.1016/j.jacl.2019.08.004 · Cited by 15
Florentin, M., Kostapanos, M. S., Anagnostis, P. G., & Liamis, G. L. (2019) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2019.1691523 · Cited by 14
Solarczyk, P., Gołębiewski, M., Slósarz, J., Łukasiewicz, M., Przysucha, T., & Puppel, K. (2020) · Animals · doi:10.3390/ani10101822 · Cited by 14
Gaspar, L., Ricardo, F., Melo, T., Domingues, P. M., Domingues, M. R., Calado, R., & Rey, F. (2022) · Journal of Food Composition and Analysis · doi:10.1016/j.jfca.2022.104871 · Cited by 13
Zhong, R., Zhu, Y., Zhang, H., Huo, Y., Huang, Y., Cheng, W., & Liang, P. (2022) · Food & Function · doi:10.1039/d2fo02736d · Cited by 13
Zhao, M., Xiao, M., Tan, Q., Ji, J., & Lu, F. Y. (2023) · PLoS ONE · doi:10.1371/journal.pone.0294861 · Cited by 13
Exploring bekasam, an indigenous fermented fish product of Indonesia: original South Sumatra region
Setiarto, R. H. B., & Herlina, V. T. (2024) · Journal of Ethnic Foods · doi:10.1186/s42779-024-00230-w · Cited by 13
Lu, X., Yang, S., He, Y., Zhao, W., Nie, M., & Sun, H. (2024) · Marine Drugs · doi:10.3390/md22090386 · Cited by 14
Capece, U., Gugliandolo, S., Morciano, C., Avolio, A., Splendore, A., Giuseppe, G. D., Ciccarelli, G., Soldovieri, L., Brunetti, M., Mezza, T., et al. (2024) · Nutrients · doi:10.3390/nu16244318 · Cited by 16
Dietary fat, salt, and sugar: a clinical perspective of the social catastrophe
Mukhopadhyay, S., Goswami, S., Mondal, S. A., & Dutta, D. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-816918-6.00003-2 · Cited by 14
Nutrition and atherosclerotic cardiovascular disease
Sapp, P. A., Riley, T. M., Tindall, A. M., Sullivan, V. K., Johnston, E. A., Petersen, K. S., & Kris‐Etherton, P. M. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-818460-8.00022-8 · Cited by 14
Self-citationSalmonids as Natural Functional Food Rich in Omega-3 PUFA
Kolanowski, W. (2021) · Applied Sciences · doi:10.3390/app11052409 · Cited by 16
Lima, R. A. M., Ferraz, S. M. M., Cardoso, V. G. K., Teixeira, C. A., & Hantao, L. W. (2022) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-022-04428-2 · Cited by 13
Ward, R. E., Cho, K., Nguyen, X. T., Vassy, J. L., Ho, Y.-L. A., Quaden, R. M., GAGNON, D. R., Wilson, P. W. F., Gaziano, J. M., & Djoussé, L. (2019) · Clinical Nutrition · doi:10.1016/j.clnu.2019.03.005 · Cited by 14
Xue, M., Liu, L., Wang, S., Su, Y., Lv, K., Zhang, M., & Yao, H. (2020) · PLoS ONE · doi:10.1371/journal.pone.0236957 · Cited by 12
Dietary fatty acids and CHD: from specific recommendations to dietary patterns
Delarue, J. (2021) · Nutrition Research Reviews · doi:10.1017/s0954422420000293 · Cited by 13
Nayda, N. C., Thomas, J. M., Delaney, C. L., & Miller, M. (2023) · Nutrition Reviews · doi:10.1093/nutrit/nuad020 · Cited by 13
Xie, Q., Liu, F., Zhang, X., & Wu, Y. (2023) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2023.165725 · Cited by 12
Encapsulation of fish oil and essential fatty acids by spray drying
Sultana, A., Adachi, S., & Yoshii, H. (2023) · Sustainable Food Technology · doi:10.1039/d3fb00099k · Cited by 12
Lee, S. Y., Jang, S. I., Cho, J. H., Do, M. Y., Lee, S., Choi, A., Lee, H. S., Yang, J., & Lee, D. K. (2024) · Gut and Liver · doi:10.5009/gnl230494 · Cited by 12
Nutritional quality of fish oil extracted from selected freshwater fish species
Ayeloja, A. A., Jimoh, W. A., & GARUBA, A.-O. (2024) · Food Chemistry Advances · doi:10.1016/j.focha.2024.100720 · Cited by 12
Liu, R., Li, P. C., Li, S., Zhuang, Y., Chen, S., Huang, Y., Zheng, Y., Xiong, Y., Wang, D. Y., He, M., et al. (2024) · LWT · doi:10.1016/j.lwt.2024.116598 · Cited by 12
Duttaroy, A. K. (2024) · Nutrients · doi:10.3390/nu16213717 · Cited by 14
Lazaridis, D. G., Ανδρίτσος, Ν. Δ., Giannakas, A. E., & Karabagias, I. K. (2025) · Sustainability · doi:10.3390/su17020720 · Cited by 12
Meta-analysis Comparing Combined Use of Eicosapentaenoic Acid and Statin to Statin Alone
Doshi, R. P., Kumar, A., Thakkar, S. J., Shariff, M., Adalja, D., Doshi, A., Taha, M., Gupta, R., Desai, R., Shah, J., et al. (2019) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2019.10.009 · Cited by 12
Exercise alleviates cardiac remodelling in diabetic cardiomyopathy via the miR-486a-5p-Mst1 pathway.
Sun, D., Wang, H., Su, Y., Lin, J. M., Zhang, M., Man, W., Song, X., Zhang, L., Guo, B., Hao, K., et al. (2021) · PubMed Central · doi:10.22038/ijbms.2020.50808.11564 · Cited by 12
Holt, P. R., Alemán, J. O., Walker, J. M., Jiang, C. S., Liang, Y., de Rosa, J. C., Giri, D. D., Iyengar, N. M., Milne, G. L., Hudis, C. A., et al. (2017) · International Journal Of Nutrition · doi:10.14302/issn.2379-7835.ijn-17-1636 · Cited by 11
Oxygenated lipid signaling in tumor-associated macrophages—focus on colon cancer
Colby, J. K., Jaoude, J. C., Liu, F., & Shureiqi, I. (2018) · Cancer and Metastasis Reviews · doi:10.1007/s10555-018-9743-z · Cited by 12
New and traditional foods in a modernized Mediterranean diet model
de Lorgeril, M., Salen, P., & Rabaeus, M. (2018) · European Journal of Clinical Nutrition · doi:10.1038/s41430-018-0308-6 · Cited by 12
Dietary Manipulations for Nonalcoholic Fatty Liver Disease (NAFLD)
Cheah, M. C. C., McCullough, A. J., & Goh, G. B. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813822-9.00005-9 · Cited by 13
Blood indices of omega-3 and omega-6 polyunsaturated fatty acids are altered in hyperglycemia
Alfhili, M. A., Alsughayyir, J., Basudan, A., Alfaifi, M. A., Awan, Z. A., Algethami, M. R., & Al‐Sheikh, Y. A. (2023) · Saudi Journal of Biological Sciences · doi:10.1016/j.sjbs.2023.103577 · Cited by 13
Rahbari, S., Salehi, A., Sharifi, S. D., & Honarbakhsh, S. (2024) · Poultry Science · doi:10.1016/j.psj.2024.104468 · Cited by 11
Mao, Q., Tian, X., Wang, X., Xu, H., Zhang, Y., & Kong, Y. (2025) · PLoS ONE · doi:10.1371/journal.pone.0316767 · Cited by 11
Zhang, Y., Min, J., & Zhang, L. (2019) · Journal of Ocean University of China · doi:10.1007/s11802-019-3620-4 · Cited by 12
Rincón‐Cervera, M. Á., Bravo, R., Freitas, R. A. M. S., López‐Arana, S., & de Camargo, A. C. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-823569-0.00005-9 · Cited by 11
Oils as a source of bioactive lipids (olive oil, palm oil, fish oil)
Rey, F., Alves, E., Gaspar, L., Conceição, M., & Domingues, M. R. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-824043-4.00013-0 · Cited by 14
Ly, R., MacIntyre, B. C., Philips, S. M., McGlory, C., Mutch, D. M., & Britz‐McKibbin, P. (2023) · Journal of Lipid Research · doi:10.1016/j.jlr.2023.100445 · Cited by 14
Oleson, S., Eagan, D. E., Kaur, S., Hertzing, W. J., Alkatan, M., Davis, J. N., Tanaka, H., & Haley, A. P. (2018) · Nutritional Neuroscience · doi:10.1080/1028415x.2018.1547857 · Cited by 11
Role of Omega-3-Fatty Acids in the Management of Diabetes and Associated Complications
Behl, T., Grover, M., Shah, K., Makkar, R., Kaur, L., Sharma, S., & Gupta, J. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813822-9.00012-6 · Cited by 11
Verwirrung um die Wirkung von Omega-3-Fettsäuren
von Schacky, C. (2019) · Der Internist · doi:10.1007/s00108-019-00687-x · Cited by 13
Bazarbashi, N., & Miller, M. J. (2020) · Expert Review of Cardiovascular Therapy · doi:10.1080/14779072.2020.1749596 · Cited by 11
Bork, C. S., Tram, L., Hjelmgaard, K., & Schmidt, E. B. (2020) · Proceedings of The Nutrition Society · doi:10.1017/s0029665120006886 · Cited by 11
Combination therapy is it in the future for successfully treating peripheral diabetic neuropathy?
Yorek, M. A. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1357859 · Cited by 12
Eicosapentaenoic acid induces macrophage Mox polarization to prevent diabetic cardiomyopathy
Li, J., Nan, W., Huang, X., Meng, H., Wang, S., Zheng, Y., Li, Y., Li, H., Zhang, Z., Du, L., et al. (2024) · EMBO Reports · doi:10.1038/s44319-024-00271-x · Cited by 10
Huang, S., Jiang, J., & Gong, H. (2024) · Scientific Reports · doi:10.1038/s41598-024-78486-0 · Cited by 11
Kelly, M. S., Beavers, C. J., Bucheit, J. D., Sisson, E. M., & Dixon, D. L. (2017) · Journal of clinical lipidology · doi:10.1016/j.jacl.2017.05.014 · Cited by 10
Terova, G., Moroni, F., Antonini, M., Bertacchi, S., Pesciaroli, C., Branduardi, P., Labra, M., Porro, D., Ceccotti, C., & Rimoldi, S. (2021) · Frontiers in Marine Science · doi:10.3389/fmars.2021.715078 · Cited by 11
Choi, J. Y., Park, H., Park, J. J., & Cho, I. H. (2022) · Food Science and Biotechnology · doi:10.1007/s10068-022-01223-8 · Cited by 10
Liu, W., Xie, X., Liu, M., Zhang, J., Liang, W., & Chen, X. (2018) · Scientific Reports · doi:10.1038/s41598-018-19193-5 · Cited by 10
Mei, Z., Chen, G., Hu, J., Lin, C., Sun, Z., Liu, C., Geng, X., Yuan, C., Qi, Q., & Zheng, Y. (2021) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqab157 · Cited by 10
Biagetti, C., Correani, A., D’Ascenzo, R., Bellagamba, M. P., Marchionni, P., Antognoli, L., Pompilio, A., Cogo, P. E., & Carnielli, V. P. (2018) · Clinical Nutrition · doi:10.1016/j.clnu.2018.10.009 · Cited by 10
Zhang, W. (2021) · Nutrition Reviews · doi:10.1093/nutrit/nuab009 · Cited by 11
Gutstein, A. S., & COPPLE, T. M. (2017) · Journal of the American Association of Nurse Practitioners · doi:10.1002/2327-6924.12535 · Cited by 10
Editorial: The role of dietary fatty acids in metabolic health
Bordoni, L., Zec, M. M., Naumovski, N., & Sergi, D. (2023) · Frontiers in Physiology · doi:10.3389/fphys.2023.1211151 · Cited by 12
Wang, X., Ruan, H., Zong, Z., Mao, F., Wang, Y., Jiao, Y., Xu, L., Yang, T., Li, W., & Liu, X. (2021) · Journal of Chromatography B · doi:10.1016/j.jchromb.2021.122895 · Cited by 9
Xue, Q., Zhu, H., Ya, R., & Huang, H. (2023) · Reviews in Cardiovascular Medicine · doi:10.31083/j.rcm2401024 · Cited by 13
Arrom, L. M., Mora, I., & Garrote, L. (2025) · Journal of Cosmetic Dermatology · doi:10.1111/jocd.70341 · Cited by 11
Liu, J., Meng, Q., Zheng, L., Yu, P., Hu, H., Zhuang, R., Ge, X., Liu, Z., Liang, X., & Zhou, X. (2022) · British Journal Of Nutrition · doi:10.1017/s0007114521004979 · Cited by 10
Bioactive lipids: Chemistry, biochemistry, and biological properties
Salsinha, A. S., Machado, M., Rodríguez-Alcalá, L. M., Gomes, A., & Pintado, M. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-824043-4.00014-2 · Cited by 12
Reprint of: Marine OMEGA-3 fatty acids in the prevention of cardiovascular disease
Mori, T. A. (2018) · Fitoterapia · doi:10.1016/j.fitote.2018.04.003 · Cited by 9
Yong, K., Mori, T. A., Chew, G. T., Beilin, L. J., Puddey, I. B., Watts, G. F., Irish, A. B., Dogra, G. K., Boudville, N. C., & Lim, W. H. (2019) · Journal of Renal Nutrition · doi:10.1053/j.jrn.2019.01.001 · Cited by 11
Ximenynic Acid Regulation of n-3 PUFA Content in Liver and Brain
Cai, F., Liu, Y. D., Hettiarachichi, D. S., Wang, F., Li, J., Sunderland, B., & Li, D. (2020) · Lifestyle Genomics · doi:10.1159/000502773 · Cited by 9
Kim, J., Hoang, T., Kim, J., Bu, S. Y., Choi, J., Park, E., Lee, S.-M., Park, E., Min, J. Y., Lee, I. S., et al. (2020) · Nutrients · doi:10.3390/nu12103203 · Cited by 10
Noflatscher, M., Schreinlechner, M., Sommer, P., Deutinger, P., Theurl, M., Kirchmair, R., Bauer, A., & Marschang, P. (2020) · Nutrients · doi:10.3390/nu12123711 · Cited by 9
Dietary PUFAs drive diverse system-level changes in lipid metabolism
Furse, S., Virtue, S., Snowden, S. G., Vidal‐Puig, A., Stevenson, P. C., Chiarugi, D., & Koulman, A. (2022) · Molecular Metabolism · doi:10.1016/j.molmet.2022.101457 · Cited by 9
Clinical, nutritional, and quality assessment of flaxseeds and their supplemented muffins
Rabail, R., Sultan, M. T., Khalid, A. R., Manzoor, M. F., Anwar, M. I., Muzammil, H. S., Shabbir, M. A., Siddeeg, A., & Aadil, R. M. (2023) · CyTA - Journal of Food · doi:10.1080/19476337.2023.2188908 · Cited by 9
Benes, L. B., Bassi, N. S., Kalot, M. A., & Davidson, M. H. (2018) · Cardiology Clinics · doi:10.1016/j.ccl.2017.12.009 · Cited by 9
Bugiardini, R., Rahaman, T., Manfrini, O., Maas, A. H. E. M., Bergami, M., Badimón, L., Mendieta, G., Vavlukis, M., Merkely, B. P., Vasiljević, Z., et al. (2025) · Cardiovascular Research · doi:10.1093/cvr/cvaf176 · Cited by 8
Mahrus, H., Zulkifli, L., Rasmi, D. A. C., & Sedijani, P. (2020) · Journal of Food Science and Technology · doi:10.1007/s13197-020-04445-y · Cited by 8
Zhang, J., Cai, A., Chen, G., Wang, X., Cai, M., Li, H., Nissen, S. E., Lip, G. Y. H., & Lin, H. (2022) · European Journal of Preventive Cardiology · doi:10.1093/eurjpc/zwac192 · Cited by 10
Dong, S., Wang, Y., Bian, J., Chen, H., Dong, J., Zhu, J., Zhang, T., Du, Q., & Zhao, R. (2024) · Nutrition Journal · doi:10.1186/s12937-024-01051-y · Cited by 9
Colussi, G., Catena, C., Fagotto, V., Darsiè, D., Brosolo, G., Bertin, N., & Sechi, L. A. (2018) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2018.1434126 · Cited by 8
Croft, D. P., Block, R., Cameron, S. J., Evans, K. A., Lowenstein, C. J., Ling, F. S. K., Zaręba, W., Hopke, P. K., Utell, M. J., Thurston, S. W., et al. (2018) · Air Quality Atmosphere & Health · doi:10.1007/s11869-018-0586-0 · Cited by 8
Evaluation of Omega-3 Status in Professional Basketball Players
Davis, J.-K., Freese, E. C., Wolfe, A. S., Basham, S. A., & Stein, K. W. (2021) · The Journal of Strength and Conditioning Research · doi:10.1519/jsc.0000000000004023 · Cited by 9
Betageri, O., Al-Turk, B., Freeman, A. M., & Aggarwal, M. (2021) · Current Cardiology Reports · doi:10.1007/s11886-021-01577-1 · Cited by 9
Zhang, C., Xie, Y., Zhou, J., Zhang, C., Xiang, Q., Zhong, Y., Xiao, J., Feng, J., Liao, B., Chen, X., et al. (2025) · Food Science & Nutrition · doi:10.1002/fsn3.70372 · Cited by 8
Zhou, L., Jiang, Y., Lin, Z., Chen, R., Niu, Y., & Kan, H. (2022) · Environmental Health · doi:10.1186/s12940-022-00908-1 · Cited by 7
Lyu, Y., Jiang, H., Sun, H., Yang, Y., Chao, Y., Huang, L., & Dong, X. (2023) · Tree Physiology · doi:10.1093/treephys/tpad061 · Cited by 7
Chao, T., Sun, J., Ge, Y., & Wang, C. (2023) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2023.10.035 · Cited by 8
Xu, B., Yuan, H., Li, X., Yu, Q., Dai, C., & Dong, Z. (2024) · Pediatric Discovery · doi:10.1002/pdi3.91 · Cited by 7
The EPA oxylipin, 12-HEPE, directly regulates human platelet activity
Goerger, K., Stanger, L., Rickenberg, A., Nguyễn, A., Lee, T., Holman, T. R., & Holinstat, M. A. (2025) · Journal of Lipid Research · doi:10.1016/j.jlr.2025.100807 · Cited by 7
Comhaire, F. H., & Decleer, W. A. E. (2020) · The Aging Male · doi:10.1080/13685538.2020.1713080 · Cited by 7
do Vale, F. M., Diógenes, M. J., & Atalaia-Barbacena, H. (2020) · Pharmacological Research · doi:10.1016/j.phrs.2020.105368 · Cited by 8
Kartikasari, L. R., Geier, M. S., Hughes, R., Bastian, S. E. P., & Gibson, R. A. (2021) · Food Research · doi:10.26656/fr.2017.5(s2).010 · Cited by 7
Effects of polyunsaturated fatty acid–rich diets and risk of non-communicable diseases
Singh, R. B., Watanabe, S., Li, D., Nakamura, T., Juneja, L. R., Takahashi, T., Wichansawakun, S., Wilczyńska, A., Jantan, I., Sulaeman, A., et al. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-819815-5.00011-2 · Cited by 7
Self-Nanoemulsification of Healthy Oils to Enhance the Solubility of Lipophilic Drugs
Rehman, M., Khan, M. Z., Tayyab, M., Madni, A., & Khalid, Q. (2022) · Journal of Visualized Experiments · doi:10.3791/63995 · Cited by 7
Li, Z., Song, W.-Q., Shen, D., Zhang, P., Zhou, J., Zhang, X., Zhang, Y., Ren, J.-J., Chen, Y., Liu, D., et al. (2022) · Clinical Nutrition · doi:10.1016/j.clnu.2022.10.002 · Cited by 7
Bork, C. S., Lundbye‐Christensen, S., Venø, S. K., Lasota, A. N., Tjønneland, A. M., Schmidt, E. B., & Overvad, K. (2023) · European Journal of Nutrition · doi:10.1007/s00394-022-03081-w · Cited by 7
Liu, X., Li, Y., Wan, X., Zhuang, P., Wu, Y., Zhang, L., Yang, A., Yao, J., Zhang, Y., & Jiao, J. (2023) · Nutrients · doi:10.3390/nu15143176 · Cited by 7
Du, C., Ying, D., Guo, Y., Cheng, Y., Han, M., Zhang, W., & Qian, H. (2018) · Biochemistry and Cell Biology · doi:10.1139/bcb-2017-0332 · Cited by 7
Metadata
- Authors
- Siscovick, D. S., Barringer, T. A., Fretts, A. M., Wu, J. H. Y., Lichtenstein, A. H., Costello, R. B., Kris-Etherton, P. M., Jacobson, T. A., Engler, M. B., Alger, H. M., Appel, L. J., & Mozaffarian, D.
- ORCID
- Venue
- Circulation
- Published
- 2017-04-11
- Volume
- 135
- Issue
- 15
- Pages
- e867-e884
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- PMC
- PMC6903779
- OpenAlex
- W2597054569
- Cited by
- 629
- References
- 52
- Citations by year
- 2026: 21 · 2025: 42 · 2024: 57 · 2023: 57 · 2022: 64 · 2021: 66 · 2020: 90 · 2019: 90 · 2018: 100 · 2017: 40
- FWCI
- 9.00
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Circulation (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Heart, Lung, and Blood Institute (R01HL101236, R01HL085710)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Physical Sciences › Chemistry › Organic Chemistry › Edible Oils Quality and Analysis
- Keywords
- omega-3 polyunsaturated fatty acids, fish oil supplementation, eicosapentaenoic acid, docosahexaenoic acid, cardiovascular disease prevention, secondary prevention, coronary artery disease, diabetes mellitus, prediabetes, high cardiovascular risk, stroke, heart failure, atrial fibrillation
- MeSH terms
- Atrial Fibrillation, Cardiovascular Diseases, Diabetes Mellitus, Fish Oils, Heart Failure, Cardiac Surgical Procedures, Humans, Primary Prevention, Risk, Fatty Acids, Omega-3, Dietary Supplements, Stroke, Diabetes Complications, Secondary Prevention
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
