The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.
Tailored Atrial Substrate Modification Based on Low-Voltage Areas in Catheter Ablation of Atrial Fibrillation
Abstract
Background—: Reduced electrogram amplitude has been shown to correlate with diseased myocardium. We describe a novel individualized approach for catheter ablation of atrial fibrillation (AF) based on low-voltage areas (LVAs) in the left atrium (LA). We sought to assess (1) the incidence of LVAs in patients undergoing AF catheter ablation, (2) the distribution of LVAs within the LA, and (3) the effect of an individualized ablation strategy on long-term rhythm outcomes. Methods and Results—: In 178 patients with paroxysmal or persistent AF, LA voltage maps were created during sinus rhythm after circumferential pulmonary vein isolation. Subsequent substrate modification was confined to the presence of LVA (<0.5 mV) and inducible regular atrial tachycardias. LVAs were identified in 35% and 10% of patients with persistent and paroxysmal AF, respectively. The LA roof and the anterior, septal, and posterior wall LA were most often affected. The 12-month atrial tachycardias/AF-free survival was 62% for patients without LVAs and 70% for patients with LVAs and tailored substrate modification ( P =0.3). Success rate in a comparison group of 26 LVA patients without further substrate modification was 27%. Conclusions—: LVAs can be found at preferred sites in 10% of patients with paroxysmal AF and in 35% of patients with persistent AF. This is the first clinical report describing a consistent voltage-based approach for substrate modification in addition to circumferential pulmonary vein isolation irrespective of AF type. Application of this limited individualized approach may have the potential to compensate for the impaired 12-month outcome of patients with endocardial structural defects.
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Atrial Fibrillation Pathophysiology: Implications for Management
Iwasaki, Y.-K., Nishida, K., Kato, T., & Nattel, S. (2011) · Circulation · doi:10.1161/circulationaha.111.019893 · Cited by 852
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Pre-existent left atrial scarring in patients undergoing pulmonary vein antrum isolation
Verma, A., Wazni, O. M., Marrouche, N. F., Martin, D. O., Kilicaslan, F., Minor, S., Schweikert, R. A., Saliba, W., Cummings, J., Burkhardt, J. D., et al. (2005) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2004.10.035 · Cited by 595
Electrophysiologic and electroanatomic changes in the human atrium associated with age
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Effects of Experimental Heart Failure on Atrial Cellular and Ionic Electrophysiology
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Mahnkopf, C., Badger, T. J., Burgon, N. S., Daccarett, M., Haslam, T. S., Badger, C. T., McGann, C. J., Akoum, N., Kholmovski, E., Macleod, R. S., et al. (2010) · Heart Rhythm · doi:10.1016/j.hrthm.2010.06.030 · Cited by 334
Catheter-induced linear lesions in theleft atrium in patients with atrial fibrillation
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Cited by
2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
Kirchhof, P., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., Castella, M., Diener, H.-C., Heidbuchel, H., Hendriks, J., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehw210 · Cited by 6,418
Self-citationCalkins, H., Hindricks, G., Cappato, R., Kim, Y.-H., Saad, E. B., Aguinaga, L., Akar, J. G., Badhwar, V., Brugada, J., Camm, J., et al. (2017) · Heart Rhythm · doi:10.1016/j.hrthm.2017.05.012 · Cited by 2,755
Self-citation2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
Kirchhof, P., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., Castella, M., Diener, H.-C., Heidbuchel, H., Hendriks, J., et al. (2016) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezw313 · Cited by 1,403
Self-citationKawai, S., Mukai, Y., Inoue, S., Yakabe, D., Nagaoka, K., Sakamoto, K., Takase, S., Chishaki, A., & Tsutsui, H. (2019) · Scientific Reports · doi:10.1038/s41598-019-48669-1 · Cited by 70
Metadata
- Authors
- Rolf, S., Kircher, S., Arya, A., Eitel, C., Sommer, P., Richter, S., Gaspar, T., Bollmann, A., Altmann, D., Piedra, C., Hindricks, G., & Piorkowski, C.
- Venue
- Circulation: Arrhythmia and Electrophysiology
- Published
- 2014-10
- Volume
- 7
- Issue
- 5
- Pages
- 825-833
- ISSN
- 1941-3084 (ISSN-L)
- 1941-3149
- OpenAlex
- W2136673459
- Cited by
- 561
- References
- 21
- FWCI
- 25.69
- Type
- journal article
- Language
- en
- Open access
- closed
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- Rolf, S., Kircher, S., Arya, A., Eitel, C., Sommer, P., Richter, S., Gaspar, T., Bollmann, A., Altmann, D., Piedra, C., Hindricks, G., & Piorkowski, C. (2014). Tailored Atrial Substrate Modification Based on Low-Voltage Areas in Catheter Ablation of Atrial Fibrillation. Circulation: Arrhythmia and Electrophysiology. https://doi.org/10.1161/circep.113.001251
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