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Cited by 299

The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.

Prediction of Cardiovascular Events and All-Cause Mortality With Erectile Dysfunction: A Systematic Review and Meta-Analysis of Cohort Studies

Open access
Vlachopoulos, Charalambos V., Terentes-Printzios, Dimitrios G., Ioakeimidis, Nikolaos K., Aznaouridis, Konstantinos A., Stefanadis, Christodoulos I.·2013·Circulation: Cardiovascular Quality and Outcomes

Abstract

Background—: Erectile dysfunction (ED) carries an independent risk for cardiovascular (CV) events. We conducted a meta-analysis of all longitudinal studies for determining the ability of ED to predict risk of clinical events and to dissect factors influencing this ability. Methods and Results—: We conducted a comprehensive search of electronic databases through July 2012. Longitudinal studies that reported relative risk (RR) estimates with 95% confidence intervals (CIs) were included. Of the 14 studies included (92 757 participants; mean follow-up, 6.1 years; 16 articles), 13 (14 articles) reported results on total CV events (91 831 individuals), 4 on CV mortality (34 761 individuals), 4 on myocardial infarction (35 523 individuals), 6 on cerebrovascular events (27 689 individuals), and 5 on all-cause mortality (17 869 individuals). The pooled RRs for the above-mentioned end points were 1.44 (95% CI, 1.27–1.63), 1.19 (95% CI, 0.97–1.46), 1.62 (95% CI, 1.34–1.96), 1.39 (95% CI, 1.23–1.57), and 1.25 (95% CI, 1.12–1.39), respectively, for men with versus without ED. The RR was higher in intermediate- compared with high- or low-CV-risk populations and with younger age. The RR for studies that diagnosed ED with the use of a questionnaire compared with a single question was higher (RR, 1.61; 95% CI, 1.38–1.86 versus RR, 1.27; 95% CI, 1.18–1.37, respectively; P =0.006). Conclusions—: ED is associated with increased risk of CV events and all-cause mortality. RR is higher at younger ages, in intermediate-risk groups, and when a questionnaire is used instead of a single question.

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Metadata

Authors
Vlachopoulos, C. V., Terentes-Printzios, D. G., Ioakeimidis, N. K., Aznaouridis, K. A., & Stefanadis, C. I.
Venue
Circulation: Cardiovascular Quality and Outcomes
Published
2013-01
Volume
6
Issue
1
Pages
99-109
ISSN
  • 1941-7705 (ISSN-L)
  • 1941-7713
OpenAlex
W2144807876
Cited by
299
References
45
FWCI
25.31
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Prediction of Cardiovascular Events and All-Cause Mortality With Erectile Dysfunction: A Systematic Review and Meta-Analysis of Cohort Studies. https://app.cochat.ai/papers/10.1161/circoutcomes.112.966903
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Vlachopoulos, C. V., Terentes-Printzios, D. G., Ioakeimidis, N. K., Aznaouridis, K. A., & Stefanadis, C. I. (2013). Prediction of Cardiovascular Events and All-Cause Mortality With Erectile Dysfunction: A Systematic Review and Meta-Analysis of Cohort Studies. Circulation: Cardiovascular Quality and Outcomes. https://doi.org/10.1161/circoutcomes.112.966903

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