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Cited by 414

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

The Multiple Phases and Faces of Wnt Signaling During Cardiac Differentiation and Development

Gessert, Susanne, Kühl, Michael·2010·Circulation Research

Abstract

Abstract : Understanding heart development on a molecular level is a prerequisite for uncovering the causes of congenital heart diseases. Therapeutic approaches that try to enhance cardiac regeneration or that involve the differentiation of resident cardiac progenitor cells or patient-specific induced pluripotent stem cells will also benefit tremendously from this knowledge. Wnt proteins have been shown to play multiple roles during cardiac differentiation and development. They are extracellular growth factors that activate different intracellular signaling branches. Here, we summarize our current understanding of how these factors affect different aspects of cardiogenesis, starting from early specification of cardiac progenitors and continuing on to later developmental steps, such as morphogenetic processes, valve formation, and establishment of the conduction system.

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Crossref · 10.1161/circresaha.110.221531

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Metadata

Authors
Gessert, S., & Kühl, M.
Venue
Circulation Research
Published
2010-07-23
Volume
107
Issue
2
Pages
186-199
ISSN
  • 0009-7330 (ISSN-L)
  • 1524-4571
OpenAlex
W2135767680
Cited by
414
References
3
FWCI
9.45
Type
journal article
Language
en
Open access
closed

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