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Mitochondria and Endothelial Function
Open accessAbstract
In contrast to their role in cell types with higher energy demands, mitochondria in endothelial cells primarily function in signaling cellular responses to environmental cues. This article provides an overview of key aspects of mitochondrial biology in endothelial cells, including subcellular location, biogenesis, dynamics, autophagy, reactive oxygen species production and signaling, calcium homeostasis, regulated cell death, and heme biosynthesis. In each section, we introduce key concepts and then review studies showing the importance of that mechanism to endothelial control of vasomotor tone, angiogenesis, and/or inflammatory activation. We particularly highlight the small number of clinical and translational studies that have investigated each mechanism in human subjects. Finally, we review interventions that target different aspects of mitochondrial function and their effects on endothelial function. The ultimate goal of such research is the identification of new approaches for therapy. The reviewed studies make it clear that mitochondria are important in endothelial physiology and pathophysiology. A great deal of work will be needed, however, before mitochondria-directed therapies are available for the prevention and treatment of cardiovascular disease.
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“Accumulating evidence implicates mitochondrial dysregulation in impaired arterial function both in animal models of cardiovascular disease (94, 161, 182)”
From Inorganic nitrite supplementation for healthy arterial aging (2014) · cites this paper as [94]
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“If metformin can offset the decline in mitochondrial function, as some studies suggest, then this effect could contribute to enhancing both healthspan and lifespan (138, 149, 150).”
From A Critical Review of the Evidence That Metformin Is a Putative Anti-Aging Drug That Enhances Healthspan and Extends Lifespan (2021) · cites this paper as [149]
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“AMPK has also been implicated in the regulation of mitochondrial biogenesis, thus providing another link between metformin, AMPK, and improved mitochondrial function (149, 150).”
From A Critical Review of the Evidence That Metformin Is a Putative Anti-Aging Drug That Enhances Healthspan and Extends Lifespan (2021) · cites this paper as [149]
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Cites
Apoptosis: A Review of Programmed Cell Death
Elmore, S. (2007) · Toxicologic Pathology · doi:10.1080/01926230701320337 · Cited by 13,853
Mootha, V. K., Lindgren, C. M., Eriksson, K.-F., Subramanian, A., Sihag, S., Lehar, J., Puigserver, P., Carlsson, E., Ridderstråle, M., Laurila, E., et al. (2003) · Nature Genetics · doi:10.1038/ng1180 · Cited by 10,197
Biochemistry and molecular cell biology of diabetic complications
Brownlee, M. (2001) · Nature · doi:10.1038/414813a · Cited by 9,107
How mitochondria produce reactive oxygen species
Murphy, M. P. (2009) · Biochemical Journal · doi:10.1042/bj20081386 · Cited by 8,207
Hydroperoxide metabolism in mammalian organs.
Chance, B., Sies, H., & Boveris, A. (1979) · Physiological Reviews · doi:10.1152/physrev.1979.59.3.527 · Cited by 5,827
The BCL-2 protein family: opposing activities that mediate cell death
Youle, R. J., & Strasser, A. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2308 · Cited by 4,806
Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
Nishikawa, T., Edelstein, D., Du, X. L., Yamagishi, S.-I., Matsumura, T., Kaneda, Y., Yorek, M. A., Beebe, D., Oates, P. J., Hammes, H.-P., et al. (2000) · Nature · doi:10.1038/35008121 · Cited by 4,277
Therapeutic potential of resveratrol: the in vivo evidence
Baur, J. A., & Sinclair, D. A. (2006) · Nature Reviews Drug Discovery · doi:10.1038/nrd2060 · Cited by 3,958
Youle, R. J., & Narendra, D. P. (2011) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3028 · Cited by 3,273
Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1
Rodgers, J. T., Lerin, C., Haas, W., Gygi, S. P., Spiegelman, B. M., & Puigserver, P. (2005) · Nature · doi:10.1038/nature03354 · Cited by 3,160
Research works printed but not linked: 1
- 10.1161/circ.126.suppl_21.A16000 · DOI
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Farhid, F., Heydari, F., Hamblin, M. R., Masoudifar, S., Sahebkar, A., & Naghinezhad, J. (2026) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2026.06.032 · Cited by 3
Widlansky, M. E., & Malik, M. A. (2014) · Springer eBooks · doi:10.1007/978-3-642-37393-0_8-1 · Cited by 3
Mitochondria, a Therapeutic Target of Aerobic Exercise for the Vascular Homeostasis
Lee, H., Kim, K., Lee, M. C., Byun, K., & Kim, J. (2018) · Exercise Science · doi:10.15857/ksep.2018.27.3.177 · Cited by 2
Salmina, A. B., Комлева, Ю. К., Малиновская, Н. А., Morgun, A. V., Тепляшина, Е. А., Lopatina, O. L., Gorina, Y. V., Kharitonova, E. V., Хилажева, Е. Д., & Shuvaev, А. N. (2021) · Biochemistry (Moscow) · doi:10.31857/s0320972521060130 · Cited by 3
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de Boer, L., de Vries, M. C., Smeitink, J. A. M., & Koopman, W. J. H. (2022) · Springer eBooks · doi:10.1007/978-3-030-67727-5_46 · Cited by 3
Bhullar, K. S., Ashkar, F., & Wu, J. (2021) · Food Chemistry Molecular Sciences · doi:10.1016/j.fochms.2021.100069 · Cited by 3
The Translational Proteome Modulated by 20(S)-Protopanaxadiol in Endothelial Cells.
Ying-Hua, S., Chen, C. C., Li, F., Cheng, J. K., Lin, M. C., & Huang, B. (2014) · PubMed Central · Cited by 3
Belyaeva, V. S., Stepenko, Y. V., Lyubimov, I. I., Kulikov, A. L., Tietze, A. A., Kochkarova, I. S., Martynova, O. V., Pokopeyko, O. N., Крупенькина, Л. А., Nagikh, A. S., et al. (2020) · Research Results in Pharmacology · doi:10.3897/rrpharmacology.6.58891 · Cited by 4
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Tang, K., Huang, C., Huang, Z., Lin, Z., Wang, Z., & Tan, N. (2025) · Journal of Ginseng Research · doi:10.1016/j.jgr.2025.05.006 · Cited by 3
Chuang, C.-C., Chen, Y.-H., Chu, F., Yang, C.-P., Ho, H., Chang, F., Lo, Y., Chen, C., & Chang, Y.-H. (2025) · International Journal of Medical Sciences · doi:10.7150/ijms.104128 · Cited by 2
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Bai, W., Yin, D.-P., Chen, G., Lu, Y., Jiang, Q., Li, K., Yao, J., & Cao, C. (2025) · Nature Communications · doi:10.1038/s41467-025-66212-x · Cited by 2
Kim, M., Kim, H. J., Lee, Y., Lee, S., Lim, D., Park, H. D., & Shin, D. W. (2025) · Molecules · doi:10.3390/molecules31010123 · Cited by 2
Shin, J. U., Jo, Y. H., Jeong, S. A., Jeong, Y. H., Son, M. G., Jeong, Y. J., Lim, B. O., & Shin, D. W. (2026) · Current Issues in Molecular Biology · doi:10.3390/cimb48020224 · Cited by 2
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Хара, М. Р., Korda, I. V., & Podilska, T. I. (2023) · Pathologia · doi:10.14739/2310-1237.2023.2.282626 · Cited by 3
Idrees, I., Taqa, G. A., & ALtaaye, S. (2022) · Egyptian Journal of Veterinary Science · doi:10.21608/ejvs.2022.156115.1381 · Cited by 2
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Aldosari, S., Awad, M. A., Gao, M. Z., McCormack, I. G., Sellke, F. W., & Abid, M. R. (2019) · Springer eBooks · doi:10.1007/978-981-13-8946-7_2 · Cited by 2
Iskra, B. S., Davis, L., Miller, H. E., Chiu, Y., Bishop, A. J. R., Chen, Y., & Aune, G. J. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.03.04.975177 · Cited by 2
Gonzalez-Ibañez, A. M., Ruíz, L. M., Jensen, E. L., Echeverría, C., Romero, V., Stiles, L., Shirihai, O. S., & Elorza, Á. A. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.07.31.230961 · Cited by 2
Xiao, W., Wang, F., Wang, X., & Wang, X. (2025) · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy · doi:10.1016/j.saa.2025.125725 · Cited by 1
Невойт, Г. В., Potyazhenko, M., Mintser, O. P., Jaruševičius, G., & Vainoras, A. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262110497 · Cited by 3
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Sato, T., Isagawa, T., Sugiura, Y., Sawaki, D., Nakagama, Y., Kuchimaru, T., Minatsuki, S., Sato, S., Ono, K., Chuluun-Erdene, A., et al. (2026) · Journal of Pharmacological Sciences · doi:10.1016/j.jphs.2026.01.008 · Cited by 2
Yuan, K., Zhao, Y., Zhang, H., Wang, K., Zhou, Y., Chen, Y., Chen, X., Zhao, Y., & Hao, Q. (2026) · Chinese Neurosurgical Journal · doi:10.1186/s41016-026-00427-9 · Cited by 1
Gajwani, P., Wang, L. X., Debnath, K., Danos-Diaz, P., Kim, Y.-M., Srivastava, S., Ye, Z., Krantz, S., Wang, D.-M., Tiruppathì, C., et al. (2026) · eLife · doi:10.7554/elife.82205 · Cited by 1
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Bowen, T. S., & Egginton, S. (2019) · Vascular Biology · doi:10.1530/vb-19-0018 · Cited by 1
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Ravi, R., & Rajesh, B. S. (2022) · Biochemistry · doi:10.5772/intechopen.106018 · Cited by 2
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Liu, J., Zhang, Y., Liu, X., Zhang, H., Liu, Y., Chen, K., Tang, M., & Sun, L. (2022) · Fishes · doi:10.3390/fishes7060315 · Cited by 1
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Busija, D. W., Rutkai, I., & Katakam, P. V. G. (2016) · Springer eBooks · doi:10.1007/978-3-319-29635-7_3 · Cited by 1
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Gajwani, P., Wang, L., Srivastava, S., Ye, Z., Kim, Y.-M., Krantz, S., Wang, D., Tiruppathì, C., Tóth, P. T., & Rehman, J. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.08.07.503084 · Cited by 1
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Li, C., Tang, X., Wang, J., Duan, H.-J., Xia, M., Guo, C., Chen, Y.-J., Wang, B., Chen, Y., Yi, Y., et al. (2023) · Research Square · doi:10.21203/rs.3.rs-709689/v2
Yamamoto, K., Maeno, R., Kawabe, K., Shimogonya, Y., & Ando, J. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.04.20.537745
Kupper, N., Pritz, E., Siwetz, M., Guettler, J., & Huppertz, B. (2023) · doi:10.3791/65919-v
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Kaczara, P., Czyżyńska-Cichoń, I., Kuś, E., Kurpińska, A., Olkowicz, M., Wojnar‐Lason, K., Pacia, M. Z., Lytvynenko, O., Baes, M. I., & Chłopicki, S. (2024) · Figshare · doi:10.6084/m9.figshare.25792787
Wang, R., Wang, J., Zhang, Z., Ma, B., Sun, S., Gao, L., & Gao, G. (2024) · Figshare · doi:10.6084/m9.figshare.26649426
Wang, R., Wang, J., Zhang, Z., Ma, B., Sun, S., Gao, L., & Gao, G. (2024) · Figshare · doi:10.6084/m9.figshare.26649429
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Wang, R., Wang, J., Zhang, Z., Ma, B., Sun, S., Gao, L., & Gao, G. (2024) · Figshare · doi:10.6084/m9.figshare.26649432
Becerra-Dominguez, L., Yu, L., Rivas, C. H., Aguirre, S., Edwards, D., Hu, I., Wu, L., Lee, T. D., Hao, X., Liu, F., et al. (2026) · Research Square · doi:10.21203/rs.3.rs-8595402/v1
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Nguyen, P. M. C. (2015) · theses.fr (ABES) · doi:10.70675/f5d28b69zead0z45d6z8d1cz92ab36aab66c
Chatterjee, S. (2020) · theses.fr (ABES) · doi:10.70675/5d269afcz42aez4bd5zaf6cz373fc60b5595
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Metadata
- Authors
- Kluge, M. A., Fetterman, J. L., & Vita, J. A.
- Affiliations
- Boston University (US)
- Venue
- Circulation Research
- Published
- 2013-04-12
- Volume
- 112
- Issue
- 8
- Pages
- 1171-1188
- ISSN
- 0009-7330 (ISSN-L)
- 1524-4571
- PMC
- PMC3700369
- OpenAlex
- W2171435588
- Cited by
- 508
- References
- 213
- Citations by year
- 2026: 25 · 2025: 44 · 2024: 49 · 2023: 34 · 2022: 60 · 2021: 52 · 2020: 49 · 2019: 33 · 2018: 37 · 2017: 37 · 2016: 25 · 2015: 25 · 2014: 34 · 2013: 4
- FWCI
- 2.76
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Circulation Research (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Heart, Lung, and Blood Institute (P01HL060886, R01HL102299, HL081587, P50HL083801, K12HL083781, P01HL081587, R01HL075795, T32HL007224, HL083781, R01HL083269, HL083801, HL102299, R01HL115391)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Mitochondrial Function and Pathology
- Health Sciences › Medicine › Physiology (medical) › Nitric Oxide and Endothelin Effects
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Autophagy in Disease and Therapy
- Keywords
- mitochondria, endothelial cells, endothelial function, mitochondrial biogenesis, mitochondrial dynamics, mitophagy, reactive oxygen species, calcium homeostasis, regulated cell death, heme biosynthesis, vascular tone, angiogenesis, inflammation, mitochondrial-targeted therapy, cardiovascular disease
- MeSH terms
- Animals, Autophagy, Endothelium, Vascular, Homeostasis, Humans, Mitochondria, Signal Transduction, Reactive Oxygen Species, Endothelial Cells
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