Impact of early evidence of atherosclerotic changes on early treatment in children with familial hypercholesterolemia
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Carotid ultrasound evidence shows that increased CIMT in children with HeFH compared with unaffected siblings can be detected from age 6, and that progression of CIMT can be ameliorated with statin therapy and/or apheresis.
“There is evidence from carotid ultrasound measurements that increased CIMT in children with HeFH compared with siblings who have not inherited HeFH can be detected from the age of 6 years onwards, and that the progression of increasing CIMT can be ameliorated with statin therapy and/ or apheresis. 311”
From 2016 ESC/EAS Guidelines for the Management of Dyslipidaemias (2016) · cites this paper as [311]
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European Guidelines on cardiovascular disease prevention in clinical practice (version 2012)
Authors/Task Force Members:, Perk, J., De Backer, G., Gohlke, H., Graham, I., Reiner, Ž., Verschuren, M., Albus, C., Benlian, P., Boysen, G., et al. (2012) · European Heart Journal · doi:10.1093/eurheartj/ehs092 · Cited by 8,490 · see citing works
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Self-citationEfficacy and Safety of Statin Therapy in Children With Familial Hypercholesterolemia
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Early statin therapy restores endothelial function in children with familial hypercholesterolemia
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Self-citationStatin Treatment in Children With Familial Hypercholesterolemia
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Efficacy and Safety of Rosuvastatin Therapy for Children With Familial Hypercholesterolemia
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Self-citationReiner, Ž. (2013) · Nutrition, Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2013.05.002 · Cited by 147 · see citing works
Self-citationCarotid intima-media thickness in young patients with familial hypercholesterolaemia.
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Self-citationMutation detection in Croatian patients with Familial Hypercholesterolemia
Pećin, I., Whittall, R., Futema, M., Sertić, J., Reiner, Ž., Leigh, S. E. A., & Humphries, S. E. (2012) · Annals of Human Genetics · doi:10.1111/j.1469-1809.2012.00735.x · Cited by 15 · see citing works
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[Three-year-old boy--a homozygote for familiar hypercholesterolemia].
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Self-citationStatins for primary prevention: problems with cardiovascular-risk estimation?
Reiner, Ž. (2013) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2013.80-c2 · Cited by 4 · see citing works
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2016 ESC/EAS Guidelines for the Management of Dyslipidaemias
Catapano, A. L., Graham, I., De Backer, G., Wiklund, O., Chapman, M. J., Drexel, H., Hoes, A. W., Jennings, C. S., Landmesser, U., Pedersen, T. R., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehw272 · Cited by 3,162 · see citing works
Self-citation2016 ESC/EAS Guidelines for the Management of Dyslipidaemias
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Backer, G. D., Besseling, J., Chapman, J., Hovingh, G. K., Kastelein, J. J. P., Kotseva, K., Ray, K. K., Reiner, Ž., Wood, D., & Bacquer, D. D. (2015) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2015.04.809 · Cited by 151 · see citing works
Self-citationManagement of patients with familial hypercholesterolaemia
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Triglyceride-Rich Lipoproteins and Novel Targets for Anti-atherosclerotic Therapy
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Self-citationA comparison of European and US guidelines for familial hypercholesterolaemia
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Effect of Bariatric Surgery on Intima Media Thickness: A Systematic Review and Meta-Analysis
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Genetic Disorders of Lipoprotein Metabolism: Diagnosis and Management
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Beleslin, B., Deljanin, M., Kanjuh, V., Parapid, B. J., Giga, V. L., Prostran, M. S., Angelkov, L., Balinovac, J., Bikicki, M., Ambrosio, G., et al. (2013)
Genetic Disorders of Lipoprotein Metabolism: Diagnosis and Management
Cupido, A. J., Stoekenbroek, R. M., & Kastelein, J. J. P. (2020) · Springer eBooks · doi:10.1007/978-3-030-45457-9_23
- Authors
- Reiner, Ž.
- Affiliations
- University Hospital Centre Zagreb (HR)
- Corresponding author
- Reiner, Željko
- ORCID
- Reiner, Željko
- Venue
- Circulation Research
- Published
- 2014-01-17
- Volume
- 114
- Issue
- 2
- Pages
- 233-235
- ISSN
- 0009-7330 (ISSN-L)
- 1524-4571
- OpenAlex
- W2152386133
- Cited by
- 26
- References
- 25
- Citations by year
- 2022: 1 · 2021: 3 · 2020: 2 · 2019: 3 · 2018: 5 · 2017: 1 · 2016: 4 · 2015: 5 · 2014: 1 · 2013: 1
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Circulation Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Lipoproteins and Cardiovascular Health
- Life Sciences › Immunology and Microbiology › Immunology › Atherosclerosis and Cardiovascular Diseases
- Health Sciences › Medicine › Surgery › Cholesterol and Lipid Metabolism
- Keywords
- familial hypercholesterolemia, atherosclerosis, children, early treatment, lipid-lowering therapy, cardiovascular risk, pediatric cardiovascular disease
- MeSH terms
- Carotid Arteries, Carotid Artery Diseases, Female, Humans, Hyperlipoproteinemia Type II, Male, Carotid Intima-Media Thickness
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