The DOI matches its Crossref record; 191 of the 191 references it cites were found in a registry or an index.
Targeting Age-Related Pathways in Heart Failure
Open accessAbstract
During aging, deterioration in cardiac structure and function leads to increased susceptibility to heart failure. The need for interventions to combat this age-related cardiac decline is becoming increasingly urgent as the elderly population continues to grow. Our understanding of cardiac aging, and aging in general, is limited. However, recent studies of age-related decline and its prevention through interventions like exercise have revealed novel pathological and cardioprotective pathways. In this review, we summarize recent findings concerning the molecular mechanisms of age-related heart failure and highlight exercise as a valuable experimental platform for the discovery of much-needed novel therapeutic targets in this chronic disease.
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2 retracted
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Single-nucleus transcriptomics reveals a gatekeeper role for FOXP1 in primate cardiac aging
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Metadata
- Authors
- Li, H., Hastings, M. H., Rhee, J., Trager, L. E., Roh, J. D., & Rosenzweig, A.
- Venue
- Circulation Research
- Published
- 2020-02-14
- Volume
- 126
- Issue
- 4
- Pages
- 533-551
- ISSN
- 0009-7330 (ISSN-L)
- 1524-4571
- OpenAlex
- W3006673240
- Cited by
- 266
- References
- 191
- FWCI
- 15.92
- Type
- journal article
- Language
- en
- Open access
- green
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- Li, H., Hastings, M. H., Rhee, J., Trager, L. E., Roh, J. D., & Rosenzweig, A. (2020). Targeting Age-Related Pathways in Heart Failure. Circulation Research. https://doi.org/10.1161/circresaha.119.315889
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
