The DOI matches its Crossref record; 179 of the 179 references it cites were found in a registry or an index.
Pathophysiology of Hypertension: The Mosaic Theory and Beyond
Open accessAbstract
Dr Irvine Page proposed the Mosaic Theory of Hypertension in the 1940s advocating that hypertension is the result of many factors that interact to raise blood pressure and cause end-organ damage. Over the years, Dr Page modified his paradigm, and new concepts regarding oxidative stress, inflammation, genetics, sodium homeostasis, and the microbiome have arisen that allow further refinements of the Mosaic Theory. A constant feature of this approach to understanding hypertension is that the various nodes are interdependent and that these almost certainly vary between experimental models and between individuals with hypertension. This review discusses these new concepts and provides an introduction to other reviews in this compendium of Circulation Research .
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Cites
Structure, function and diversity of the healthy human microbiome
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Diet rapidly and reproducibly alters the human gut microbiome
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From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites
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Cited by
Mancia, G., Kreutz, R., Brunström, M., Burnier, M., Grassi, G., Januszewicz, A., Muiesan, M. L., Tsioufis, K., Agabiti-Rosei, E., Algharably, E. A. E., et al. (2023) · Journal of Hypertension · doi:10.1097/hjh.0000000000003480 · Cited by 3,473
Metadata
- Authors
- Harrison, D. G., Coffman, T. M., & Wilcox, C. S.
- Venue
- Circulation Research
- Published
- 2021-04-02
- Volume
- 128
- Issue
- 7
- Pages
- 847-863
- ISSN
- 0009-7330 (ISSN-L)
- 1524-4571
- OpenAlex
- W3152101335
- Cited by
- 365
- References
- 179
- FWCI
- 29.94
- Type
- journal article
- Language
- en
- Open access
- green
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- Harrison, D. G., Coffman, T. M., & Wilcox, C. S. (2021). Pathophysiology of Hypertension: The Mosaic Theory and Beyond. Circulation Research. https://doi.org/10.1161/circresaha.121.318082
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.