Cited by 2,977Cardiovascular Health and Disease PreventionCerebrovascular and Carotid Artery DiseasesDiabetes, Cardiovascular Risks, and Lipoproteins

The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.

Prediction of Clinical Cardiovascular Events With Carotid Intima-Media Thickness: A Systematic Review and Meta-Analysis

Lorenz, Matthias W., Markus, Hugh S., Bots, Michiel L., Rosvall, Maria, Sitzer, Matthias·2007·Circulation

DOI 10.1161/circulationaha.106.628875

Open this paper in CoChat — free account

Abstract

Background— Carotid intima-media thickness (IMT) is increasingly used as a surrogate marker for atherosclerosis. Its use relies on its ability to predict future clinical cardiovascular end points. We performed a systematic review and meta-analysis of data to examine this association. Methods and Results— Using a prespecified search strategy, we identified 8 relevant studies and compared study design, measurement protocols, and reported data. We identified sources of heterogeneity between studies. The assumption of a linear relationship between IMT and risk was challenged by use of a graphical technique. To obtain a pooled estimate of the relative risk per IMT difference, we performed a meta-analysis based on random effects models. The age- and sex-adjusted overall estimates of the relative risk of myocardial infarction were 1.26 (95% CI, 1.21 to 1.30) per 1–standard deviation common carotid artery IMT difference and 1.15 (95% CI, 1.12 to 1.17) per 0.10-mm common carotid artery IMT difference. The age- and sex-adjusted relative risks of stroke were 1.32 (95% CI, 1.27 to 1.38) per 1–standard deviation common carotid artery IMT difference and 1.18 (95% CI, 1.16 to 1.21) per 0.10-mm common carotid artery IMT difference. Major sources of heterogeneity were age distribution, carotid segment definition, and IMT measurement protocol. The relationship between IMT and risk was nonlinear, but the linear models fitted relatively well for moderate to high IMT values. Conclusions— Carotid IMT is a strong predictor of future vascular events. The relative risk per IMT difference is slightly higher for the end point stroke than for myocardial infarction. In future IMT studies, ultrasound protocols should be aligned with published studies. Data for younger individuals are limited and more studies are required.

Integrity signals

Registry

Crossref · 10.1161/circulationaha.106.628875

Cites

25 of 25 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Measuring inconsistency in meta-analyses
Higgins, J. P. T., Thompson, S. G., Deeks, J. J., & Altman, D. G. (2003) · BMJ · doi:10.1136/bmj.327.7414.557 · Cited by 63,139
Meta-analysis in clinical trials
DerSimonian, R., & Laird, N. (1986) · Controlled Clinical Trials · doi:10.1016/0197-2456(86)90046-2 · Cited by 39,552
Trim and Fill: A Simple Funnel‐Plot–Based Method of Testing and Adjusting for Publication Bias in Meta‐Analysis
Duval, S., & Tweedie, R. (2000) · Biometrics · doi:10.1111/j.0006-341x.2000.00455.x · Cited by 14,099
Carotid-Artery Intima and Media Thickness as a Risk Factor for Myocardial Infarction and Stroke in Older Adults
O'Leary, D. H., Polak, J. F., Kronmal, R. A., Manolio, T. A., Burke, G. L., & Wolfson, S. K. (1999) · New England Journal of Medicine · doi:10.1056/nejm199901073400103 · Cited by 4,685
The Cardiovascular Health Study: design and rationale.
Fried, L. P., Borhani, N. O., Enright, P., Furberg, C. D., Gardin, J. M., Kronmal, R. A., Kuller, L. H., Manolio, T. A., Mittelmark, M. B., Newman, A., et al. (1991) · Annals of Epidemiology · doi:10.1016/1047-2797(91)90005-w · Cited by 3,652
A Nonparametric “Trim and Fill” Method of Accounting for Publication Bias in Meta-Analysis
Duval, S., & Tweedie, R. (2000) · Journal of the American Statistical Association · doi:10.1080/01621459.2000.10473905 · Cited by 2,955
Intimal plus medial thickness of the arterial wall: a direct measurement with ultrasound imaging.
Pignoli, P., Tremoli, E., Poli, A., Oreste, P., & Paoletti, R. (1986) · Circulation · doi:10.1161/01.cir.74.6.1399 · Cited by 2,404
Common Carotid Intima-Media Thickness and Risk of Stroke and Myocardial Infarction
Bots, M. L., Hoes, A. W., Koudstaal, P. J., Albert Hofman, D., & Grobbee, D. E. (1997) · Circulation · doi:10.1161/01.cir.96.5.1432 · Cited by 2,333
Self-citation
Association of coronary heart disease incidence with carotid arterial wall thickness and major risk factors: the Atherosclerosis Risk in Communities (ARIC) Study, 1987–1993
Chambless, L. E., Heiss, G., Folsom, A. R., Rosamond, W., Szklo, M., Sharrett, A. R., & Clegg, L. X. (1997) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a009302 · Cited by 1,990
Mannheim Carotid Intima-Media Thickness Consensus (2004–2006)
Touboul, P., Hennerici, M. G., Meairs, S. P., Adams, H., Amarenco, P., Bornstein, N. M., Csiba, L., Desvarieux, M., Ebrahim, S. B. J., Fatar, M., et al. (2006) · Cerebrovascular Diseases · doi:10.1159/000097034 · Cited by 1,511
Self-citation

Flagged first, then by citations

Show all 25 references

Research works printed but not linked: 2

10.1161/circ.96.5.1432 · DOI
10.1161/str.22.9.1926258 · DOI

Sorted by citations

Items 401–500 of 1,003

Long‐term health outcomes in young women with polycystic ovary syndrome: A narrative review
Allen, L. A., Shrikrishnapalasuriyar, N., & Rees, A. (2021) · Clinical Endocrinology · doi:10.1111/cen.14609 · Cited by 75
Kawasaki Disease: Pathology, Risks, and Management
Seki, M., & Minami, T. (2022) · Vascular Health and Risk Management · doi:10.2147/vhrm.s291762 · Cited by 63
Lessons From the Past and Promises for the Future for Carotid Intima-Media Thickness
Bots, M. L., & Sutton-Tyrrell, K. (2012) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2011.12.061 · Cited by 63
Self-citation
Effects of Fenofibric Acid on Carotid Intima-Media Thickness in Patients With Mixed Dyslipidemia on Atorvastatin Therapy
Davidson, M. H., Rosenson, R. S., Maki, K. C., Nicholls, S. J., Ballantyne, C. M., Mazzone, T., Carlson, D. M., Williams, L. A., Kelly, M. T., Camp, H. S., et al. (2014) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.113.302926 · Cited by 63
Impact of Bed Rest on Conduit Artery Remodeling
van Duijnhoven, N. T. L., GREEN, D. J., Felsenberg, D., Belavý, D. L., Hopman, M. T. E., & Thijssen, D. H. J. (2010) · Hypertension · doi:10.1161/hypertensionaha.110.152868 · Cited by 63
Individuals with Metabolically Healthy Overweight/Obesity Have Higher Fat Utilization than Metabolically Unhealthy Individuals
Pujia, A., Gazzaruso, C., Ferro, Y., Mazza, E., Maurotti, S., Russo, C., Lazzaro, V., Romeo, S., & Montalcini, T. (2016) · Nutrients · doi:10.3390/nu8010002 · Cited by 63
Subclinical Atherosclerosis and Markers of Immune Activation in HIV-Infected Children and Adolescents
Sainz, T., Álvarez-Fuente, M., Navarro, M. L., Díaz, L., Rojo, P., Blázquez‐Gamero, D., de José, M. I., Ramos, J. T., Villar, S. S., Martínez, J., et al. (2013) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0b013e3182a9466a · Cited by 63
The relationship of erectile dysfunction and subclinical cardiovascular disease: A systematic review and meta-analysis
Osondu, C. U., Vo, B., Oni, E., Blaha, M. J., Veledar, E., Feldman, T., Agatston, A. S., Nasir, K., & Aneni, E. C. (2017) · Vascular Medicine · doi:10.1177/1358863x17725809 · Cited by 62
Non-HDL Cholesterol Levels in Childhood and Carotid Intima-Media Thickness in Adulthood
Juonala, M., Wu, F., Sinaiko, A. R., Woo, J. G., Urbina, E. M., Jacobs, D. R., Steinberger, J., Prineas, R. J., Koskinen, J. M., Sabin, M. A., et al. (2020) · PEDIATRICS · doi:10.1542/peds.2019-2114 · Cited by 63
Small-Molecule Inhibitors of Signal Transducer and Activator of Transcription 3 Protect Against Angiotensin II–Induced Vascular Dysfunction and Hypertension
Johnson, A. W., Kinzenbaw, D. A., Modrick, M. L., & Faraci, F. M. (2013) · Hypertension · doi:10.1161/hypertensionaha.111.00299 · Cited by 63
“In vivo” imaging of atherosclerosis
Gallino, A., Stuber, M., Crea, F., Falk, E., Corti, R., Lekakis, J. P., Schwitter, J., Camici, P. G., Gaemperli, O., Valentino, M. D., et al. (2012) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2012.04.007 · Cited by 67
Prognostic impact of carotid intima-media thickness and carotid plaques on the development of micro- and macrovascular complications in individuals with type 2 diabetes: the Rio de Janeiro type 2 diabetes cohort study
Cardoso, C. R. L., Salles, G. C., Leite, N. C., & Salles, G. F. (2019) · Cardiovascular Diabetology · doi:10.1186/s12933-019-0809-1 · Cited by 62
Impaired Fetal Growth and Arterial Wall Thickening: A Randomized Trial of Omega-3 Supplementation
Skilton, M. R., Ayer, J. G., Harmer, J. A., Webb, K., Leeder, S., Marks, G. B., & Celermajer, D. S. (2012) · PEDIATRICS · doi:10.1542/peds.2011-2472 · Cited by 62
Increased levels of platelet activation markers are positively associated with carotid wall thickness and other atherosclerotic risk factors in obese patients
Nagy, B., Fülöp, T., Varga, Z., Karányi, Z., Magyar, M. T., Oláh, L., Papp, M., Facskó, A., Kappelmayer, J., Paragh, G., et al. (2011) · Thrombosis and Haemostasis · doi:10.1160/th11-01-0030 · Cited by 62
Is there a correlation between OSAS duration/severity and carotid intima-media thickness?
Ciccone, M. M., Scicchitano, P., Mitacchione, G., Zito, A., Gesualdo, M., Caputo, P., Damiani, M. F., Sassara, M., Favale, S., Resta, O., et al. (2012) · Respiratory Medicine · doi:10.1016/j.rmed.2011.12.016 · Cited by 62
Carotid intima–media thickness and the prediction of vascular events
Robertson, C. M., Gerry, F., Fowkes, R., & Price, J. F. (2012) · Vascular Medicine · doi:10.1177/1358863x12445103 · Cited by 62
Conduit Diameter and Wall Remodeling in Elite Athletes and Spinal Cord Injury
Rowley, N., Dawson, E. A., Hopman, M. T. E., George, K., Whyte, G. P., Thijssen, D. H. J., & GREEN, D. J. (2011) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e31823f6887 · Cited by 62
Noninvasive cardiovascular imaging for evaluating subclinical target organ damage in hypertensive patients
Filardi, P. P., Coca, A., Galderisi, M., Paolillo, S., Alpendurada, F., SIMONE, G. D., Donal, E., Kahan, T., Mancia, G., Redón, J., et al. (2017) · Journal of Hypertension · doi:10.1097/hjh.0000000000001396 · Cited by 66
Evaluation of body fat distribution in pcos and its association with carotid atherosclerosis and insulin resistance
Karabulut, A., Yaylali, G. F., Demirlenk, S., Sevket, O., & Acun, A. (2012) · Gynecological Endocrinology · doi:10.3109/09513590.2011.589929 · Cited by 61
A Voxel-Based Fully Convolution Network and Continuous Max-Flow for Carotid Vessel-Wall-Volume Segmentation From 3D Ultrasound Images
Zhou, R., Guo, F., Azarpazhooh, M. R., Spence, J. D., Ukwatta, E., Ding, M., & Fenster, A. (2020) · IEEE Transactions on Medical Imaging · doi:10.1109/tmi.2020.2975231 · Cited by 61
Mediterranean Diet and Endothelial Function: A Review of its Effects at Different Vascular Bed Levels
Torres-Peña, J. D., Rangel-Zúñiga, O. A., Alcala-Diaz, J. F., López‐Miranda, J., & Delgado‐Lista, J. (2020) · Nutrients · doi:10.3390/nu12082212 · Cited by 67
Immune checkpoint inhibitor treatment and atherosclerotic cardiovascular disease: an emerging clinical problem
Poels, K., Neppelenbroek, S. I. M., Kersten, M. J., Antoni, M. L., Lutgens, E., & Seijkens, T. T. P. (2021) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2021-002916 · Cited by 64
Normal‐weight central obesity and risk of cardiovascular and microvascular events in adults with prediabetes or diabetes: Chinese and British cohorts
Zhong, P., Tan, S., Zhu, Z., Zhu, Z., Liang, Y., Huang, W., & Wang, W. (2023) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.3707 · Cited by 65
New and Emerging Risk Factors for Coronary Heart Disease
Akhabue, E., Thiboutot, J. P., Cheng, J.-W., Lerakis, S., Vittorio, T. J., Christodoulidis, G., Grady, K. M., & Kosmas, C. E. (2013) · The American Journal of the Medical Sciences · doi:10.1097/maj.0b013e31828aab45 · Cited by 64
Conventional and Mendelian randomization analyses suggest no association between lipoprotein(a) and early atherosclerosis: the Young Finns Study
Mika Kivimaki, B., Magnussen, C. G., Juonala, M., Kähönen, M. A. P., Kettunen, J., Loo, B.-M., Lehtimäki, T. J., Viikari, J. S. A., & Raitakari, O. T. (2010) · International Journal of Epidemiology · doi:10.1093/ije/dyq205 · Cited by 61
Recurrence and long-term maternal health risks of hypertensive disorders of pregnancy: a population-based study
Andersgaard, A. B., Acharya, G., Mathiesen, E. B., Johnsen, S. H., Straume, B., & Øian, P. (2011) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2011.09.032 · Cited by 61
Anti-Atherosclerotic Effects of a Phytoestrogen-Rich Herbal Preparation in Postmenopausal Women
Myasoedova, V. A., Kirichenko, T. V., Melnichenko, A. А., Orekhova, V. A., Ravani, A. L., Poggio, P., Sobenin, I. A., Bobryshev, Y. V., & Orekhov, A. N. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17081318 · Cited by 65
Carotid Bifurcation Geometry and Atherosclerosis
Spanos, K. T., Petrocheilou, G. M., Karathanos, C., Labropoulos, N., Mikhailidis, D. P., & Giannoukas, A. D. (2016) · Angiology · doi:10.1177/0003319716678741 · Cited by 61
The role of noninvasive cardiovascular testing, applied clinical nutrition and nutritional supplements in the prevention and treatment of coronary heart disease
Houston, M. C. (2018) · Therapeutic Advances in Cardiovascular Disease · doi:10.1177/1753944717743920 · Cited by 62
Artificial intelligence framework for predictive cardiovascular and stroke risk assessment models: A narrative review of integrated approaches using carotid ultrasound
Jamthikar, A. D., Gupta, D., Saba, L., Khanna, N. N., Višković, K., Mavrogeni, S. I., Laird, J. R., Sattar, N. A., Johri, A. M., Pareek, G., et al. (2020) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2020.104043 · Cited by 64
Maximum carotid intima-media thickness improves the prediction ability of coronary artery stenosis in type 2 diabetic patients without history of coronary artery disease
Irie, Y., Katakami, N., Kaneto, H., Kasami, R., Sumitsuji, S., Yamasaki, K., Tachibana, K., Kuroda, T., Sakamoto, K., Umayahara, Y., et al. (2012) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2012.01.022 · Cited by 60
Measures of cardiovascular risk and subclinical atherosclerosis in a cohort of women with a remote history of preeclampsia
McDonald, S. D., Ray, J. G., Teo, K. K., Jung, H., Salehian, O., Yusuf, S., & Lonn, E. (2013) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2013.04.020 · Cited by 60
Cardiovascular Disease Risk in the Offspring of Diabetic Women: The Impact of the Intrauterine Environment
Marco, L. J., McCloskey, K., Vuillermin, P., Burgner, D. P., Said, J. M., & Ponsonby, A. (2012) · Experimental Diabetes Research · doi:10.1155/2012/565160 · Cited by 63
Effectiveness of lifestyle intervention in overweight children
Reinehr, T. (2011) · Proceedings of The Nutrition Society · doi:10.1017/s0029665111000577 · Cited by 60
Dietary supplementation with n-3 polyunsaturated fatty acids in early childhood: effects on blood pressure and arterial structure and function at age 8 y
Ayer, J. G., Harmer, J. A., Wei, X., Toelle, B. G., Webb, K., Almqvist, C., Marks, G. B., & Celermajer, D. S. (2009) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2009.27811 · Cited by 62
Ultrasound Detection of Increased Carotid Intima-Media Thickness and Carotid Plaque in an Office Practice Setting: Does It Affect Physician Behavior or Patient Motivation?
Korcarz, C. E., DeCara, J. M., Hirsch, A. T., Mohler, E. R., Pogue, B. W., Postley, J. E., Tzou, W. S., & Stein, J. H. (2008) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2008.05.001 · Cited by 60
Association between atherosclerosis and Alzheimer's disease: A systematic review and meta‐analysis
Xie, B., Shi, X., Xing, Y., & Tang, Y. (2020) · Brain and Behavior · doi:10.1002/brb3.1601 · Cited by 62
Role of klotho and fibroblast growth factor 23 in arterial calcification, thickness, and stiffness: a meta-analysis of observational studies
Wungu, C. D. K., Susilo, H., Alsagaff, M. Y., Witarto, B. S., Witarto, A. P., Pakpahan, C., & Gusnanto, A. (2024) · Scientific Reports · doi:10.1038/s41598-024-56377-8 · Cited by 59
Carotid atherosclerosis severity in relation to glycemic status: A cross-sectional population study
Mostaza, J. M., Lahoz, C., Salinero-Fort, M. Á., de Burgos‐Lunar, C., Laguna, F., Estirado, E., García-Iglesias, F., González-Alegre, T., Cornejo, V., Sabín, C., et al. (2015) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2015.07.028 · Cited by 60
Lone atrial fibrillation: what is known and what is to come
Potpara, T., & Lip, G. Y. H. (2011) · International Journal of Clinical Practice · doi:10.1111/j.1742-1241.2010.02618.x · Cited by 59
Carotid Intima-Media Thickness and Long-Term Exposure to Traffic-Related Air Pollution in Middle-Aged Residents of Taiwan: A Cross-Sectional Study
Su, T., Hwang, J., Shen, Y., & Chan, C. (2015) · Environmental Health Perspectives · doi:10.1289/ehp.1408553 · Cited by 59
Assessment and Relevance of Carotid Intima-Media Thickness (C-IMT) in Primary and Secondary Cardiovascular Prevention
Ravani, A. L., Werba, J. P., Frigerio, B., Sansaro, D., Amato, M., Tremoli, E., & Baldassarre, D. (2014) · Current Pharmaceutical Design · doi:10.2174/1381612820666141013121545 · Cited by 58
Low-dose atorvastatin improves dyslipidemia and vascular function in patients with primary biliary cirrhosis after one year of treatment
Stojaković, T., Claudel, T., Putz‐Bankuti, C., Fauler, G., Scharnagl, H., Wagner, M., Sourij, H., Stauber, R. E., Winkler, K., März, W., et al. (2009) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2009.08.052 · Cited by 59
Vascular Biomarkers in the Prediction of Clinical Cardiovascular Disease
Roman, M. J., Kizer, J. R., Best, L. G., Lee, E. T., Howard, B. V., Shara, N. M., & Devereux, R. B. (2011) · Hypertension · doi:10.1161/hypertensionaha.111.181925 · Cited by 59
Effects of 24-week treatment with acarbose on glucagon-like peptide 1 in newly diagnosed type 2 diabetic patients: a preliminary report
Zheng, M., Yang, J., Shan, C., Zhou, H.-T., Xu, Y., Wang, Y., Ren, H., Chang, B., & Chen, L. (2013) · Cardiovascular Diabetology · doi:10.1186/1475-2840-12-73 · Cited by 58
Relationship of lipid oxidation with subclinical atherosclerosis and 10-year coronary events in general population
Gómez, M., Vila, J., Elosúa, R., Balaguer, L. M., Bruguera, J., Sala, J., Masià, R., Covas, M. I., Marrugat, J., & Fitó, M. (2013) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2013.10.026 · Cited by 59
Continuous and Dichotomous Metabolic Syndrome Definitions in Youth Predict Adult Type 2 Diabetes and Carotid Artery Intima Media Thickness: The Cardiovascular Risk in Young Finns Study
Magnussen, C. G., Cheriyan, S. S., Sabin, M. A., Juonala, M., Koskinen, J. M., Thomson, R. J., Skilton, M. R., Kähönen, M. A. P., Laitinen, T. P., Taittonen, L. M., et al. (2015) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2015.10.093 · Cited by 59
Carotid intima-media thickness is an independent predictor of all-cause mortality and cardiovascular morbidity in patients with diabetes mellitus type 2 and chronic kidney disease
Roumeliotis, A. K., Roumeliotis, S. K., Panagoutsos, S. A., Theodoridis, M., Argyriou, C., Tavridou, A., & Georgiadis, G. S. (2019) · Renal Failure · doi:10.1080/0886022x.2019.1585372 · Cited by 59
Methods to evaluate vascular function: a crucial approach towards predictive, preventive, and personalised medicine
Sena, C. M., Gonçalves, L. M. M., & Seiça, R. M. F. (2022) · The EPMA Journal · doi:10.1007/s13167-022-00280-7 · Cited by 60
[Usefulness of imaging techniques and novel biomarkers in the prediction of cardiovascular risk in patients with chronic kidney disease in Spain: the NEFRONA project].
Junyent, M., Martínez‐Alonso, M., Borràs, M., Bertriu, A., Coll, B., Craver, L., Marco, M. P., Sarró, F., Valdivielso, J. M., & Fernández, E. (2010) · PubMed · doi:10.3265/nefrologia.pre2010.jan.10216 · Cited by 58
Interleukin-10 protects against aging-induced endothelial dysfunction
Kinzenbaw, D. A., Chu, Y., Silva, R. A. P., Didion, S. P., & Faraci, F. M. (2013) · Physiological Reports · doi:10.1002/phy2.149 · Cited by 58
Basilar Artery Diameter Is an Independent Predictor of Incident Cardiovascular Events
Tanaka, M. R., Sakaguchi, M., Miwa, K., Okazaki, S., Furukado, S., Yagita, Y., Mochizuki, H., & Kitagawa, K. (2013) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.113.301467 · Cited by 58
The Association Between Endocan Levels and Subclinical Atherosclerosis in Patients With Type 2 Diabetes Mellitus
Lv, Y., Zhang, Y., Shi, W., Liu, J., Li, Y., Zhou, Z., He, Q., Wei, S., Liu, J., & Quan, J. (2017) · The American Journal of the Medical Sciences · doi:10.1016/j.amjms.2017.02.004 · Cited by 58
Carotid Ultrasound Phenotypes Are Biologically Distinct
Spence, J. D. (2015) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.115.306209 · Cited by 58
Body Mass Index From Early to Late Childhood and Cardiometabolic Measurements at 11 to 12 Years
Lycett, K., Juonala, M., Magnussen, C. G., Norrish, D., Mensah, F. K., Liu, R., Clifford, S. A., Carlin, J. B., Olds, T., Saffery, R., et al. (2020) · PEDIATRICS · doi:10.1542/peds.2019-3666 · Cited by 56
Association of Fitness With Vascular Intima-Media Thickness and Elasticity in Adolescence
Pahkala, K., Laitinen, T. T., Heinonen, O. J., Viikari, J. S. A., Rönnemaa, T., Niinikoski, H., Helajärvi, H., Juonala, M., Simell, O., & Raitakari, O. T. (2013) · PEDIATRICS · doi:10.1542/peds.2013-0041 · Cited by 58
Reduced Atherosclerotic Burden in Subjects With Genetically Determined Low Oxidative Stress
Violi, F., Pignatelli, P., Pignata, C., Plebani, A., Rossi, P., Sanguigni, V., Carnevale, R., Soresina, A., Finocchi, A., Cirillo, E., et al. (2013) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.112.300438 · Cited by 57
Coronary Artery Calcium and Carotid Artery Intima Media Thickness and Plaque: Clinical Use in Need of Clarification
Zaid, M., Fujiyoshi, A., Kadota, A., Abbott, R. D., & Miura, K. (2016) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.rv16005 · Cited by 56
Lipopolysaccharide-binding protein is associated with arterial stiffness in patients with type 2 diabetes: a cross-sectional study
Sakura, T., Morioka, T., Shioi, A., Kakutani, Y., Miki, Y., Yamazaki, Y., Motoyama, K., Mori, K., Fukumoto, S., Shoji, T., et al. (2017) · Cardiovascular Diabetology · doi:10.1186/s12933-017-0545-3 · Cited by 57
Thyrotropin aggravates atherosclerosis by promoting macrophage inflammation in plaques
Yang, C., Lu, M. H., Chen, W., He, Z., Hou, X. H., Feng, M., Zhang, H., Bo, T., Zhou, X., Yu, Y., et al. (2019) · The Journal of Experimental Medicine · doi:10.1084/jem.20181473 · Cited by 56
Varying Definitions of Carotid Intima‐Media Thickness and Future Cardiovascular Disease: A Systematic Review and Meta‐Analysis
Ling, Y., Wan, Y., Barinas‐Mitchell, E., Fujiyoshi, A., Cui, H., Maimaiti, A., Xu, R., Li, J., Suo, C., & Zaid, M. (2023) · Journal of the American Heart Association · doi:10.1161/jaha.123.031217 · Cited by 59
Effect of folic acid supplementation on the progression of carotid intima-media thickness: A meta-analysis of randomized controlled trials
Qin, X., Xu, M., Zhang, Y., Li, J., Xu, X. P., Wang, X., Xu, X., & Huo, Y. (2011) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2011.12.007 · Cited by 56
Carotid intima–media and adventitial thickening: Comparison of new and established ultrasound and magnetic resonance imaging techniques
Skilton, M. R., Boussel, L., Bonnet, F., Bernard, S., Douek, P., Moulin, P., & Sérusclat, A. (2011) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2010.12.036 · Cited by 56
Association of Natural Intake of Dietary Plant Sterols with Carotid Intima–Media Thickness and Blood Lipids in Chinese Adults: A Cross-Section Study
Wang, P., Chen, Y., Li-ping, H., Chen, C., Zhang, B., Xue, W., & Su, Y. (2012) · PLoS ONE · doi:10.1371/journal.pone.0032736 · Cited by 56
Maternal cigarette smoking is associated with reduced high-density lipoprotein cholesterol in healthy 8-year-old children
Ayer, J. G., Belousova, E., Harmer, J. A., David, C., Marks, G. B., & Celermajer, D. S. (2011) · European Heart Journal · doi:10.1093/eurheartj/ehr174 · Cited by 57
Associations between objectively measured physical activity intensity in childhood and measures of subclinical cardiovascular disease in adolescence: prospective observations from the European Youth Heart Study
Ried‐Larsen, M., Grøntved, A., Møller, N. C., Larsen, K. T., Froberg, K., & Andersen, L. B. (2013) · British Journal of Sports Medicine · doi:10.1136/bjsports-2012-091958 · Cited by 56
Adherence to a Dietary Approaches to Stop Hypertension (DASH)-type diet over the life course and associated vascular function: a study based on the MRC 1946 British birth cohort
Maddock, J., Ziauddeen, N., Ambrosini, G. L., Wong, A., Hardy, R., & Ray, S. (2018) · British Journal Of Nutrition · doi:10.1017/s0007114517003877 · Cited by 58
White blood cell count is associated with carotid and femoral atherosclerosis
Ortega, E., Gilabert, R., Núñez, I., Cofán, M., Sala‐Vila, A., de Groot, E., & Ros, E. (2012) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2011.12.038 · Cited by 56
Effect of magnesium supplementation on endothelial function: A systematic review and meta-analysis of randomized controlled trials
Mofrad, M. D., Djafarian, K., Mozaffari, H., & Shab‐Bidar, S. (2018) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2018.04.020 · Cited by 56
Cardiovascular Health Effects of Shift Work with Long Working Hours and Night Shifts: Study Protocol for a Three-Year Prospective Follow-Up Study on Industrial Workers
Lunde, L.-K., Skare, Ø., Mamen, A., Sirnes, P. A., Aass, H. C. D., Øvstebø, R., Goffeng, E. M., Matre, D., Nielsen, P., Heglum, H. S. A., et al. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17020589 · Cited by 63
Ultrasonographic measurements of subclinical carotid atherosclerosis in prediction of ischemic stroke
Mathiesen, E. B., & Johnsen, S. H. (2009) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.2009.01210.x · Cited by 55
Usefulness of lipoprotein ratios in assessing carotid atherosclerosis in Japanese type 2 diabetic patients.
Katakami, N., Kaneto, H., Osonoi, T., Saitou, M., Takahara, M., Sakamoto, F., Yamamoto, K., Yasuda, T., Matsuoka, T., Matsuhisa, M., et al. (2011) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2010.10.035 · Cited by 51
Carotid Artery Wall Thickness and Risk of Stroke Subtypes
Ohira, T., Shahar, E., Iso, H., Chambless, L. E., Rosamond, W. D., Sharrett, A. R., & Folsom, A. R. (2010) · Stroke · doi:10.1161/strokeaha.110.592261 · Cited by 55
Utility of Different Blood Pressure Measurement Components in Childhood to Predict Adult Carotid Intima-Media Thickness
Koskinen, J. M., Juonala, M., Dwyer, T., Venn, A., Petkevičienė, J., Čeponienė, I., Bazzano, L., Chen, W., Sabin, M. A., Burns, T. L., et al. (2018) · Hypertension · doi:10.1161/hypertensionaha.118.12225 · Cited by 55
Childhood origins of arterial disease
Charakida, M., Deanfield, J. E., & Halcox, J. (2007) · Current Opinion in Pediatrics · doi:10.1097/mop.0b013e3282eff585 · Cited by 55
Early Life Family Conflict, Social Interactions, and Carotid Artery Intima-Media Thickness in Adulthood
John‐Henderson, N. A., Kamarck, T. W., Muldoon, M. F., & Manuck, S. B. (2015) · Psychosomatic Medicine · doi:10.1097/psy.0000000000000259 · Cited by 54
Coronary Artery Calcium Improves Risk Assessment in Adults With a Family History of Premature Coronary Heart Disease
Patel, J., Rifai, M. A., Blaha, M. J., Budoff, M. J., Post, W. S., Polak, J. F., Bluemke, D. A., Scheuner, M. T., Kronmal, R. A., Blumenthal, R. S., et al. (2015) · Circulation Cardiovascular Imaging · doi:10.1161/circimaging.115.003186 · Cited by 54
Long‐term effects of weight loss after bariatric surgery on functional and structural markers of atherosclerosis
Tschoner, A., Sturm, W., Gelsinger, C., Ress, C., Laimer, M. W., Engl, J., Laimer, E., Mühlmann, G., Mittermair, R. P., Kaser, S., et al. (2013) · Obesity · doi:10.1002/oby.20357 · Cited by 54
Carotid, aortic arch and coronary calcification are related to history of stroke: The Rotterdam Study
Elias‐Smale, S. E., Odink, A. E., Wieberdink, R. G., Albert Hofman, D., Hunink, M. G. M., Krestin, G. P., Koudstaal, P. J., Breteler, M. M. B., van der Lugt, A., & Witteman, J. C. M. (2010) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2010.06.037 · Cited by 54
Differences between daytime and nighttime blood pressure variability regarding systemic atherosclerotic change and renal function
Kawai, T., Ohishi, M., Kamide, K., Nakama, C., Onishi, M., Ito, N., Takami, Y., Takeya, Y., & Rakugi, H. (2012) · Hypertension Research · doi:10.1038/hr.2012.162 · Cited by 54
Current diagnostic concepts to detect coronary artery disease in women
Stangl, V., Witzel, V., Baumann, G., & Stangl, K. (2008) · European Heart Journal · doi:10.1093/eurheartj/ehn047 · Cited by 54
The association of thyroid function with carotid artery plaque burden and strokes in a population-based sample from a previously iodine-deficient area
Dörr, M., Empen, K., Robinson, D. M., Wallaschofski, H., Felix, S. B., & Völzke, H. (2008) · European Journal of Endocrinology · doi:10.1530/eje-08-0140 · Cited by 54
Do low testosterone levels contribute to ill-health during male ageing?
Yeap, B. B., de Araújo, A. B., & Wittert, G. (2012) · Critical Reviews in Clinical Laboratory Sciences · doi:10.3109/10408363.2012.725461 · Cited by 53
Heart Failure in Acute Ischemic Stroke
Cuadrado‐Godia, E., Ois, Á., & Roquer, J. (2010) · Current Cardiology Reviews · doi:10.2174/157340310791658776 · Cited by 56
Comprehensive assessment of vascular health in patients; towards endothelium-guided therapy
Frołow, M., Dróżdż, A., Kowalewska, A., Niżankowski, R., & Chłopicki, S. (2015) · Pharmacological Reports · doi:10.1016/j.pharep.2015.05.010 · Cited by 54
The evaluation of carotid intima-media thickness in children with familial Mediterranean fever
Peru, H., Altun, B., Doğan, M., Kara, F., Elmacı, A. M., & Oran, B. (2007) · Clinical Rheumatology · doi:10.1007/s10067-007-0764-1 · Cited by 54
Early Atherosclerosis Relates to Urinary Albumin Excretion and Cardiovascular Risk Factors in Adolescents With Type 1 Diabetes: Adolescent Type 1 Diabetes cardio-renal Intervention Trial (AdDIT)
Maftei, O., Peña, A. S., Sullivan, T., Jones, T. W., Donaghue, K. C., Cameron, F. J., Davis, E. A., Cotterill, A. M., Craig, M. E., Gent, R. J., et al. (2014) · Diabetes Care · doi:10.2337/dc14-0700 · Cited by 53
Trends and Challenges of Wearable Multimodal Technologies for Stroke Risk Prediction
Chen, Y.-H., & Sawan, M. (2021) · Sensors · doi:10.3390/s21020460 · Cited by 55
BRAP Activates Inflammatory Cascades and Increases the Risk for Carotid Atherosclerosis
Liao, Y., Wang, Y., Guo, Y.-C., Ozaki, K., Tanaka, T., Lin, H., Chang, M.-H., Chen, K., Yu, M., Sheu, S., et al. (2011) · Molecular Medicine · doi:10.2119/molmed.2011.00043 · Cited by 53
Incidence of Ischemic Stroke in Relation to Asymptomatic Carotid Artery Atherosclerosis in Subjects with Normal Blood Pressure
Li, C., Engström, G., Berglund, G. L., Janzon, L., & Hedblad, B. (2008) · Cerebrovascular Diseases · doi:10.1159/000149577 · Cited by 53
Protocol for Measuring Carotid Intima-Media Thickness That Best Correlates With Cardiovascular Risk and Target Organ Damage
Gómez-Marcos, M. Á., Recio-Rodriguez, J. I., Patino-Alonso, M. C., Agudo‐Conde, C., Gómez‐Sánchez, L., Gómez‐Sánchez, M., Rodríguez‐Sánchez, E., & García‐Ortiz, L. (2012) · American Journal of Hypertension · doi:10.1038/ajh.2012.72 · Cited by 53
Carotid Intima-Media Thickness Among Human Immunodeficiency Virus–Infected Patients Without Coronary Calcium
Hsue, P. Y., Ordovas, K. G., Lee, T. T. H., Reddy, G. P., Gotway, M. B., Schnell, A., Ho, J. E., Selby, V. N., Madden, E., Martin, J. N., et al. (2011) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2011.10.036 · Cited by 53
HDL-C, triglycerides and carotid IMT: A meta-analysis of 21,000 patients with automated edge detection IMT measurement
Touboul, P., Labreuche, J., Bruckert, É., Schargrodsky, H., Prati, P., Tosetto, A., Hernández-Hernández, R., Woo, K.-S., Silva, H., Vicaut, É., et al. (2013) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2013.10.011 · Cited by 52
Pulse Wave Velocity, Intima Media Thickness, and Flow-mediated Dilatation in Patients with Normotensive Normoglycemic Inflammatory Bowel Disease
Öztürk, K., Guler, A. K., Cakir, M., Özen, A., Demirci, H., Türker, T., Demirbaş, Ş., Uygun, A., Gülşen, M., & Bağcı, S. (2015) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000355 · Cited by 53
Impact of Cardiovascular Risk Factors on Carotid Intima-Media Thickness and Degree of Severity: A Cross-Sectional Study
Ren, L., Cai, J., Liang, J., Li, W., & Sun, Z. (2015) · PLoS ONE · doi:10.1371/journal.pone.0144182 · Cited by 53
Glucose variability for cardiovascular risk factors in type 2 diabetes: a meta-analysis
Liang, S., Yin, H., Wei, C., Xie, L., He, H., & Liu, X. (2017) · Journal of Diabetes & Metabolic Disorders · doi:10.1186/s40200-017-0323-5 · Cited by 54
Retinal Vessel Diameters and Blood Pressure Progression in Children
Lona, G., Endes, K., Köchli, S., Infanger, D., Zahner, L., & Hanssen, H. (2020) · Hypertension · doi:10.1161/hypertensionaha.120.14695 · Cited by 53
Alcohol Consumption and Ankle-to-Brachial Index: Results from the Cardiovascular Risk Survey
Xie, X., Ma, Y.-T., Yang, Y., Li, X., Liu, F., Huang, D., Fu, Z.-Y., Ma, X., Chen, B., & Huang, Y. (2010) · PLoS ONE · doi:10.1371/journal.pone.0015181 · Cited by 52
Surrogate markers in clinical trials—Challenges and opportunities
Duivenvoorden, R., de Groot, E., Stroes, E. S. G., & Kastelein, J. J. P. (2008) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2008.12.009 · Cited by 52
Effect of vascular risk factors on increase in carotid and femoral intima-media thickness. Identification of a risk scale
Berni, A., Giuliani, A., Tartaglia, F., Tromba, L., Sgueglia, M., Blasi, S., & Russo, G. (2011) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2011.01.034 · Cited by 52

Authors: Lorenz, M. W., Markus, H. S., Bots, M. L., Rosvall, M., & Sitzer, M.
Affiliations: Goethe University Frankfurt (DE)
ORCID: Lorenz, Matthias W.
Markus, Hugh S.
Bots, Michiel L.
Rosvall, Maria
Venue: Circulation
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2007-01-30
Volume: 115
Issue: 4
Pages: 459-467
ISSN: 0009-7322 (ISSN-L)
1524-4539
DOI: 10.1161/circulationaha.106.628875
OpenAlex: W2072751592
Cited by: 2,977
References: 25
Citations by year: 2026: 87 · 2025: 74 · 2024: 88 · 2023: 120 · 2022: 121 · 2021: 134 · 2020: 159 · 2019: 137 · 2018: 163 · 2017: 156 · 2016: 185 · 2015: 210 · 2014: 212 · 2013: 242 · 2012: 204
FWCI: 107.90
Type: journal article
Language: en
Open access: closed
Locations: Circulation (publishedVersion)
PubMed (publishedVersion)
Lund University Publications (Lund University) (submittedVersion)
Funders: University of Washington
University of Oxford
University of North Carolina at Chapel Hill
National Heart, Lung, and Blood Institute
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cerebrovascular and Carotid Artery Diseases
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Keywords: carotid intima-media thickness, cardiovascular risk prediction, myocardial infarction, stroke, atherosclerosis, common carotid artery, surrogate markers
MeSH terms: Carotid Arteries, Carotid Artery Diseases, Humans, Myocardial Infarction, Predictive Value of Tests, Risk Factors, Tunica Intima, Tunica Media, Stroke

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Prediction of Clinical Cardiovascular Events With Carotid Intima-Media Thickness: A Systematic Review and Meta-Analysis

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks