Endothelial Function and Dysfunction: Testing and Clinical Relevance

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Missing Pieces in the NF-κB Puzzle

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Circulating endothelial progenitor cells, vascular function, and cardiovascular risk

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Cardiovascular effects of flavanol-rich chocolate in patients with heart failure

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Senescence-Induced Oxidative Stress Causes Endothelial Dysfunction

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An Anxious Heart: Anxiety and the Onset of Cardiovascular Diseases

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Cerebral small vessel disease alters neurovascular unit regulation of microcirculation integrity involved in vascular cognitive impairment

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Heat shock protein 70 is secreted from endothelial cells by a non-classical pathway involving exosomes

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Clinical evidence demonstrating the utility of inorganic nitrate in cardiovascular health

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Statins Control Oxidized LDL-Mediated Histone Modifications and Gene Expression in Cultured Human Endothelial Cells

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Impact of Telmisartan Versus Ramipril on Renal Endothelial Function in Patients With Hypertension and Type 2 Diabetes

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Effects of n–3 fatty acids on macro- and microvascular function in subjects with type 2 diabetes mellitus

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Protective Effect of Irisin on Atherosclerosis via Suppressing Oxidized Low Density Lipoprotein Induced Vascular Inflammation and Endothelial Dysfunction

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Role of hydrogen sulfide in endothelial dysfunction: Pathophysiology and therapeutic approaches

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Whey protein lowers blood pressure and improves endothelial function and lipid biomarkers in adults with prehypertension and mild hypertension: results from the chronic Whey2Go randomized controlled trial

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Endothelial Dysfunction in Covid-19 Infection

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Mechanosensitive microRNAs—role in endothelial responses to shear stress and redox state

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Hypertension and dyslipidaemia in obesity and insulin resistance: Pathophysiology, impact on atherosclerotic disease and pharmacotherapy

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Vascular Generation of Tumor Necrosis Factor-α Reduces Nitric Oxide Availability in Small Arteries From Visceral Fat of Obese Patients

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Type 2 diabetes mellitus worsens arterial stiffness in hypertensive patients through endothelial dysfunction

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Human endothelial dysfunction: EDRFs

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Retinal microvascular dysfunction in heart failure

Nägele, M. P., Barthelmes, J., Ludovici, V., Cantatore, S., von Eckardstein, A., Enseleit, F., Lüscher, T. F., Ruschitzka, F. T., Sudano, I., & Flammer, A. J. (2017) · European Heart Journal · doi:10.1093/eurheartj/ehx565 · Cited by 120

Testing Endothelial Function and its Clinical Relevance

Poredoš, P., & Jezovnik, M. K. (2012) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.14340 · Cited by 120

Noninvasive Visualization of Coronary Artery Endothelial Function in Healthy Subjects and in Patients With Coronary Artery Disease

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Trained Immunity and Reactivity of Macrophages and Endothelial Cells

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Endothelial Function as a Functional Expression of Cardiovascular Risk Factors

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Reference intervals for brachial artery flow-mediated dilation and the relation with cardiovascular risk factors

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Edward F. Adolph Distinguished Lecture: The remarkable anti-aging effects of aerobic exercise on systemic arteries

Seals, D. R. (2014) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00362.2014 · Cited by 118

Role of oxidative stress in carbon nanotube-generated health effects

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Activated Platelets Induce Endothelial Cell Activation via an Interleukin-1β Pathway in Systemic Lupus Erythematosus

Nhek, S., Clancy, R. M., Lee, K. A., Allen, N., Barrett, T. J., Marcantoni, E., Nwaukoni, J., Rasmussen, S. E., Rubin, M., Newman, J. D., et al. (2017) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.116.308126 · Cited by 123

Atherosclerosis and flow: roles of epigenetic modulation in vascular endothelium

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Endothelial dysfunction in conduit arteries and in microcirculation. Novel therapeutic approaches

Tousoulis, D., Simopoulou, C., Παπαγεωργίου, Ν., Oikonomou, E. K., Hatzis, G., Siasos, G., Tsiamis, E. G., & Stefanadis, C. (2014) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2014.06.003 · Cited by 120

High-risk periodontal pathogens contribute to the pathogenesis of atherosclerosis

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Metformin in cardiovascular diabetology: a focused review of its impact on endothelial function

Ding, Y., Zhou, Y., Ling, P., Feng, X., Luo, S., Zheng, X., Little, P. J., Xu, S., & Weng, J. (2021) · Theranostics · doi:10.7150/thno.64706 · Cited by 121

SIRT3 interactions with FOXO3 acetylation, phosphorylation and ubiquitinylation mediate endothelial cell responses to hypoxia

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Inorganic nitrate ingestion improves vascular compliance but does not alter flow-mediated dilatation in healthy volunteers

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Dihydromyricetin protects endothelial cells from hydrogen peroxide-induced oxidative stress damage by regulating mitochondrial pathways

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Activation of Endothelial and Coagulation Systems in Left Ventricular Assist Device Recipients

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Anti‐Atherosclerotic Effects of Vitamins D and E in Suppression of Atherogenesis

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Glaucoma Is Associated with Peripheral Vascular Endothelial Dysfunction

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Cardiovascular effects of glucagon-like peptide 1 receptor agonists: from mechanistic studies in humans to clinical outcomes

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Effect of induced hypoglycemia on inflammation and oxidative stress in type 2 diabetes and control subjects

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Endothelial dysfunction, endothelial nitric oxide bioavailability, tetrahydrobiopterin, and 5-methyltetrahydrofolate in cardiovascular disease. Where are we with therapy?

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Vitamin D in Vascular Calcification: A Double-Edged Sword?

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The effects of garlic extract upon endothelial function, vascular inflammation, oxidative stress and insulin resistance in adults with type 2 diabetes at high cardiovascular risk. A pilot double blind randomized placebo controlled trial

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Vildagliptin Improves Endothelium-Dependent Vasodilatation in Type 2 Diabetes

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Cocoa consumption dose-dependently improves flow-mediated dilation and arterial stiffness decreasing blood pressure in healthy individuals

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Effect of vitamin C and vitamin E supplementation on endothelial function: a systematic review and meta-analysis of randomised controlled trials

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Nitric Oxide, Oxidative Stress, and p66Shc Interplay in Diabetic Endothelial Dysfunction

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Endothelial dysfunction in patients with spontaneous venous thromboembolism

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Acute Effects of Coffee on Endothelial Function in Healthy Subjects

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Endothelial Dysfunction, Carotid Intima-Media Thickness, and Accelerated Atherosclerosis in Rheumatoid Arthritis

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Cocoa, Blood Pressure, and Vascular Function

Ludovici, V., Barthelmes, J., Nägele, M. P., Enseleit, F., Ferri, C., Flammer, A. J., Ruschitzka, F. T., & Sudano, I. (2017) · Frontiers in Nutrition · doi:10.3389/fnut.2017.00036 · Cited by 114

Significance of chitinase-3-like protein 1 in the pathogenesis of inflammatory diseases and cancer

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Postprandial lipaemia, oxidative stress and endothelial function: a review

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The Bilirubin-Increasing Drug Atazanavir Improves Endothelial Function in Patients With Type 2 Diabetes Mellitus

Dekker, D., Dorresteijn, M. J., Pijnenburg, M., Heemskerk, S., Rasing-Hoogveld, A., Burger, D. M., Wagener, F. A. D. T. G., & Smits, P. (2010) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.110.211789 · Cited by 109

High-density lipoproteins as modulators of endothelial cell functions: alterations in patients with coronary artery disease

Kratzer, A., Giral, H., & Landmesser, U. (2014) · Cardiovascular Research · doi:10.1093/cvr/cvu139 · Cited by 112

Contribution of redox-dependent activation of endothelial Nlrp3 inflammasomes to hyperglycemia-induced endothelial dysfunction

Chen, Y., Wang, L., Pitzer, A. L., Li, X., Li, P.-L., & Zhang, Y. (2016) · Journal of Molecular Medicine · doi:10.1007/s00109-016-1481-5 · Cited by 108

The implication of periodontitis in vascular endothelial dysfunction

Gurav, A. N. (2014) · European Journal of Clinical Investigation · doi:10.1111/eci.12322 · Cited by 111

Soccer improves fitness and attenuates cardiovascular risk factors in hypertensive men.

Krustrup, P., Randers, M., Andersen, L. J., Jackman, S., Bangsbo, J., & Hansen, P. (2013) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3182777051 · Cited by 118

Measurement of endothelial function and its clinical utility for cardiovascular risk

Al-Qaisi, M. (2008) · Vascular Health and Risk Management · doi:10.2147/vhrm.s2769 · Cited by 108

Hazard identification of particulate matter on vasomotor dysfunction and progression of atherosclerosis

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Berberine improves endothelial function by reducing endothelial microparticles-mediated oxidative stress in humans

Cheng, F., Wang, Y., Li, J., Su, C., Wu, F., Xia, W., Yang, Z., Yu, B., Qiu, Y., & Tao, J. (2012) · International Journal of Cardiology · doi:10.1016/j.ijcard.2012.03.090 · Cited by 108

Microalbuminuria: causes and implications

Singh, A. K., & Satchell, S. C. (2011) · Pediatric Nephrology · doi:10.1007/s00467-011-1777-1 · Cited by 109

Impact of Vitamin D Supplementation on Arterial Vasomotion, Stiffness and Endothelial Biomarkers in Chronic Kidney Disease Patients

Chitalia, N., Ismail, T. S. T., Tooth, L., Boa, F. G., Hampson, G., Goldsmith, D. J. A., Kaski, J. C., & Banerjee, D. (2014) · PLoS ONE · doi:10.1371/journal.pone.0091363 · Cited by 107

Is the ratio of flow-mediated dilation and shear rate a statistically sound approach to normalization in cross-sectional studies on endothelial function?

Atkinson, G., Batterham, A. M., Black, M. A., Cable, N. T., Hopkins, N. D., Dawson, E. A., Thijssen, D. H. J., Jones, H., Tinken, T. M., & GREEN, D. J. (2009) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00779.2009 · Cited by 107

TRPV1 agonism inhibits endothelial cell inflammation via activation of eNOS/NO pathway

Wang, Y., Cui, L., Xu, H., Liu, S., Zhu, F.-Y., Yan, F., Shen, S., & Zhu, M. (2017) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2017.03.016 · Cited by 107

Modest effect on plaque progression and vasodilatory function in atherosclerosis-prone mice exposed to nanosized TiO2

Mikkelsen, L., Sheykhzade, M., Jensen, K. A., Saber, A. T., Jacobsen, N. R., Vogel, U. B., Wallin, H., Loft, S. H., & Möller, P. (2011) · Particle and Fibre Toxicology · doi:10.1186/1743-8977-8-32 · Cited by 106

Immunomodulatory and antioxidant function of albumin stabilises the endothelium and improves survival in a rodent model of chronic liver failure

García‐Martínez, R., Andreola, F., Mehta, G., Poulton, K., Oria, M., Jover‐Cobos, M., Soeda, J., Macnaughtan, J., Chiara, F. D., Habtesion, A., et al. (2014) · Journal of Hepatology · doi:10.1016/j.jhep.2014.10.031 · Cited by 106

Microvascular endothelial dysfunction is associated with albuminuria and CKD in older adults

Seliger, S. L., Salimi, S., Pierre, V., Giffuni, J., Katzel, L. I., & Parsa, A. (2016) · BMC Nephrology · doi:10.1186/s12882-016-0303-x · Cited by 105

Impact of Increased Oxidative Stress on Cardiovascular Diseases in Women With Polycystic Ovary Syndrome

Duică, F., Dănilă, C. A., Boboc, A. E., Antoniadis, P., Condrat, C. E., Onciul, S., Suciu, N., Creţoiu, S. M., Varlas, V. N., & Crețoiu, D. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.614679 · Cited by 110

New Insights into Endothelial Dysfunction in Cardiometabolic Diseases: Potential Mechanisms and Clinical Implications

Gallo, G., & Savoia, C. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25052973 · Cited by 105

Low-Density Lipoprotein-Cholesterol-Induced Endothelial Dysfunction and Oxidative Stress: The Role of Statins

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Role of NADPH Oxidase in Endothelial Ischemia/Reperfusion Injury in Humans

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Reliable Endothelial Function Testing

Celermajer, D. S. (2008) · Circulation · doi:10.1161/circulationaha.108.775155 · Cited by 104

Assessment of Arterial Stiffness, A Translational Medicine Biomarker System for Evaluation of Vascular Risk

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Analysis of retinal arteriolar structure in never-treated patients with essential hypertension

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Advanced glycation end products upregulate lysyl oxidase and endothelin-1 in human aortic endothelial cells via parallel activation of ERK1/2–NF-κB and JNK–AP-1 signaling pathways

Adamopoulos, C., Piperi, C., Gargalionis, A. N., Dalagiorgou, G., Spilioti, E., Korkolopoulou, P. A., Diamanti‐Kandarakis, E., & Papavassiliou, A. G. (2015) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-015-2091-z · Cited by 101

VEGF promotes endothelial progenitor cell differentiation and vascular repair through connexin 43

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An Observational Cohort Study of the Kynurenine to Tryptophan Ratio in Sepsis: Association with Impaired Immune and Microvascular Function

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Tea, flavonoids, and cardiovascular health: endothelial protection

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