Contribution of redox-dependent activation of endothelial Nlrp3 inflammasomes to hyperglycemia-induced endothelial dysfunction

A role for mitochondria in nlrp3 inflammasome activation

Zhou, R., Yazdi, A. S., Menu, P., & Tschopp, J. (2011) · Nature · doi:10.1038/nature09663 · Cited by 5,602 · see citing works

The Inflammasomes

Schroder, K., & Tschopp, J. (2010) · Cell · doi:10.1016/j.cell.2010.01.040 · Cited by 5,475 · see citing works

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

Duewell, P., Kono, H., Rayner, K. J., Sirois, C. M., Vladimer, G., Bauernfeind, F. G., Abela, G. S., Franchi, L., Nuñez, G., Schnurr, M., et al. (2010) · Nature · doi:10.1038/nature08938 · Cited by 4,026 · see citing works

Activation and regulation of the inflammasomes

Latz, E., Xiao, T. S., & Stutz, A. (2013) · Nature Reviews Immunology · doi:10.1038/nri3452 · Cited by 2,884 · see citing works

Endothelial Function and Dysfunction: Testing and Clinical Relevance

Deanfield, J. E., Halcox, J. P., & Rabelink, T. J. (2007) · Circulation · doi:10.1161/circulationaha.106.652859 · Cited by 2,710 · see citing works

Role of Endothelial Dysfunction in Atherosclerosis

Davignon, J., & Ganz, P. (2004) · Circulation · doi:10.1161/01.cir.0000131515.03336.f8 · Cited by 2,513 · see citing works

Inflammasomes in health and disease

Strowig, T., Henao-Mejia, J., Elinav, E., & Flavell, R. (2012) · Nature · doi:10.1038/nature10759 · Cited by 2,230 · see citing works

Combination of high-fat diet-fed and low-dose streptozotocin-treated rat: A model for type 2 diabetes and pharmacological screening

Srinivasan, K. K., Viswanad, B., Asrat, L., Kaul, C. L., & Ramarao, P. (2005) · Pharmacological Research · doi:10.1016/j.phrs.2005.05.004 · Cited by 1,879 · see citing works

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

Franchi, L., Eigenbrod, T., Muñoz-Planillo, R., & Nuñez, G. (2009) · Nature Immunology · doi:10.1038/ni.1703 · Cited by 1,834 · see citing works

Signaling Mechanisms Regulating Endothelial Permeability

Mehta, D., & Malik, A. B. (2005) · Physiological Reviews · doi:10.1152/physrev.00012.2005 · Cited by 1,711 · see citing works

Endothelial Cell-to-Cell Junctions: Molecular Organization and Role in Vascular Homeostasis

Bazzoni, G., & Dejana, E. (2004) · Physiological Reviews · doi:10.1152/physrev.00035.2003 · Cited by 1,384 · see citing works

Diabetes-Related Microvascular and Macrovascular Diseases in the Physical Therapy Setting

Cade, W. T. (2008) · Physical Therapy · doi:10.2522/ptj.20080008 · Cited by 1,096 · see citing works

Activation of Protein Kinase C Isoforms and Its Impact on Diabetic Complications

Geraldes, P., & King, G. L. (2010) · Circulation Research · doi:10.1161/circresaha.110.217117 · Cited by 993 · see citing works

Redox Regulation of NLRP3 Inflammasomes: ROS as Trigger or Effector?

Abais, J. M., Xia, M., Zhang, Y., Boini, K. M., & Li, P. (2014) · Antioxidants and Redox Signaling · doi:10.1089/ars.2014.5994 · Cited by 936 · see citing works

Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome

Misawa, T., Takahama, M., Kozaki, T., Lee, H., Zou, J., Saitoh, T., & Akira, S. (2013) · Nature Immunology · doi:10.1038/ni.2550 · Cited by 863 · see citing works

VE-Cadherin and Endothelial Adherens Junctions: Active Guardians of Vascular Integrity

Giannotta, M., Trani, M., & Dejana, E. (2013) · Developmental Cell · doi:10.1016/j.devcel.2013.08.020 · Cited by 854 · see citing works

Active Caspase-1 Is a Regulator of Unconventional Protein Secretion

Keller, M., Rüegg, A., Werner, S., & Beer, H. (2008) · Cell · doi:10.1016/j.cell.2007.12.040 · Cited by 851 · see citing works

Endothelial dysfunction: cardiovascular risk factors, therapy, and outcome.

Hadi, H. A. R., Carr, C. S., & Suwaidi, J. M. S. A. (2005) · PubMed Central · Cited by 807 · see citing works

Novel role of PKR in inflammasome activation and HMGB1 release

Lü, B., Nakamura, T., Inouye, K., Li, J., Tang, Y., Lundbäck, P., Valdés‐Ferrer, S. I., Olofsson, P. S., Kalb, T. H., Roth, J., et al. (2012) · Nature · doi:10.1038/nature11290 · Cited by 772 · see citing works

Hyperglycemia-induced Oxidative Stress and its Role in Diabetes Mellitus Related Cardiovascular Diseases

Fiorentino, T. V., Prioletta, A., Zuo, P., & Folli, F. B. (2013) · Current Pharmaceutical Design · doi:10.2174/1381612811319320005 · Cited by 766 · see citing works

Cytokines and chemokines at the crossroads of neuroinflammation, neurodegeneration, and neuropathic pain

Ramesh, G., MacLean, A. G., & Philipp, M. T. (2013) · Mediators of Inflammation · doi:10.1155/2013/480739 · Cited by 639 · see citing works

Endothelial dysfunction in diabetes mellitus.

Hadi, H. A. R., & Suwaidi, J. M. S. A. (2007) · Europe PMC (PubMed Central) · Cited by 568 · see citing works

Shear Stress–Initiated Signaling and Its Regulation of Endothelial Function

Zhou, J., Li, Y.-S. J., & Chien, S. (2014) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.114.303422 · Cited by 564 · see citing works

Hyperglycemia-Induced Reactive Oxygen Species Increase Expression of the Receptor for Advanced Glycation End Products (RAGE) and RAGE Ligands

Yao, D., & Brownlee, M. (2009) · Diabetes · doi:10.2337/db09-0801 · Cited by 526 · see citing works

Endothelial adherens and tight junctions in vascular homeostasis, inflammation and angiogenesis

Wallez, Y., & Huber, P. (2007) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2007.09.003 · Cited by 472 · see citing works

A role for the NLRP3 inflammasome in metabolic diseases—did Warburg miss inflammation?

Wen, H., Ting, J. P. ‐., & O'Neill, L. A. J. (2012) · Nature Immunology · doi:10.1038/ni.2228 · Cited by 455 · see citing works

Avoiding Papillary Muscle Infarction With Myocardial Contrast Echocardiographic Guidance of Nonsurgical Septal Reduction Therapy for Hypertrophic Obstructive Cardiomyopathy

Nagueh, S. F., Lakkis, N. M., Middleton, K. J., Franklin, J. L., & Spencer, W. H. (2004) · Circulation · doi:10.1161/01.cir.0000115644.35804.8b · Cited by 425 · see citing works

Nlrp3-inflammasome activation in non-myeloid-derived cells aggravates diabetic nephropathy

Shahzad, K., Bock, F. M., Dong, W., Wang, H., Kopf, S., Kohli, S., Al‐Dabet, M. M., Ranjan, S., Wolter, J., Wacker, C., et al. (2014) · Kidney International · doi:10.1038/ki.2014.271 · Cited by 413 · see citing works

NLRP3 Gene Silencing Ameliorates Diabetic Cardiomyopathy in a Type 2 Diabetes Rat Model

Luo, B., Li, B., Wang, W., Liu, X., Xia, Y., Zhang, C., Zhang, M., Zhang, Y., & An, F. (2014) · PLoS ONE · doi:10.1371/journal.pone.0104771 · Cited by 408 · see citing works

Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase and PKB signaling

Schreibelt, G., Kooij, G., Reijerkerk, A., van Doorn, R., Gringhuis, S. I., van der Pol, S., Weksler, B. B., Romero, I. A., Couraud, P., Piontek, J., et al. (2007) · The FASEB Journal · doi:10.1096/fj.07-8329com · Cited by 347 · see citing works

The Caspase-1 Digestome Identifies the Glycolysis Pathway as a Target during Infection and Septic Shock

Shao, W., Yeretssian, G., Doiron, K., Hussain, S. N. A., & Saleh, M. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m708182200 · Cited by 321 · see citing works

HMGB1 B box increases the permeability of Caco-2 enterocytic monolayers and impairs intestinal barrier function in mice

Sappington, P. L., Yang, R., Yang, H., Tracey, K. J., Delude, R. L., & Fink, M. P. (2002) · Gastroenterology · doi:10.1053/gast.2002.35391 · Cited by 319 · see citing works

ATP release and purinergic signaling in NLRP3 inflammasome activation

Gombault, A., Baron, L., & Couillin, I. (2013) · Frontiers in Immunology · doi:10.3389/fimmu.2012.00414 · Cited by 308 · see citing works

High-Glucose Stimulation Increases Reactive Oxygen Species Production Through the Calcium and Mitogen-Activated Protein Kinase-Mediated Activation of Mitochondrial Fission

Yu, T., Jhun, B. S., & Yoon, Y. (2010) · Antioxidants and Redox Signaling · doi:10.1089/ars.2010.3284 · Cited by 286 · see citing works

Monounsaturated Fatty Acid–Enriched High-Fat Diets Impede Adipose NLRP3 Inflammasome–Mediated IL-1β Secretion and Insulin Resistance Despite Obesity

Finucane, O. M., Lyons, C. L., Murphy, A. M., Reynolds, C. M., Klinger, R. W., Healy, N. P., Cooke, A. A., Coll, R. C., McAllan, L., Nilaweera, K. N., et al. (2015) · Diabetes · doi:10.2337/db14-1098 · Cited by 281 · see citing works

Endothelial Dysfunction in Diabetes: From Mechanisms to Therapeutic Targets

Potenza, M., Gagliardi, S., Nacci, C., Carratu, M., & Montagnani, M. (2009) · Current Medicinal Chemistry · doi:10.2174/092986709787002853 · Cited by 280 · see citing works

Vimentin regulates activation of the NLRP3 inflammasome

dos Santos, G., Rogel, M. R., Baker, M. A., Troken, J. R., Urich, D., Morales‐Nebreda, L., Sennello, J. A., Kutuzov, M. A., Sitikov, A. S., Davis, J. M., et al. (2015) · Nature Communications · doi:10.1038/ncomms7574 · Cited by 269 · see citing works

Overexpression of the Sarcoplasmic Reticulum Ca2+-ATPase Improves Myocardial Contractility in Diabetic Cardiomyopathy

Trost, S. U., Belke, D. D., Bluhm, W. F., Meyer, M., Swanson, E., & DILLMANN, W. H. (2002) · Diabetes · doi:10.2337/diabetes.51.4.1166 · Cited by 262 · see citing works

HMGB1 induces human lung endothelial cell cytoskeletal rearrangement and barrier disruption

Wolfson, R. K., Chiang, E. T., & Garcia, J. G. N. (2010) · Microvascular Research · doi:10.1016/j.mvr.2010.11.010 · Cited by 194 · see citing works

Interleukin-1β (IL-1β) Processing Pathway

Weber, A., Wasiliew, P., & Kracht, M. (2010) · Science Signaling · doi:10.1126/scisignal.3105cm2 · Cited by 184 · see citing works

Hyperglycemia and Endothelial Dysfunction in Atherosclerosis: Lessons from Type 1 Diabetes

Funk, S. D., Yurdagul, A., & Orr, A. W. (2012) · International Journal of Vascular Medicine · doi:10.1155/2012/569654 · Cited by 176 · see citing works

How is inflammation initiated? Individual influences of IL-1, IL-18 and HMGB1

Keyel, P. A. (2014) · Cytokine · doi:10.1016/j.cyto.2014.03.007 · Cited by 175 · see citing works

Presenilin-1 Mutation Increases Neuronal Vulnerability to Focal IschemiaIn Vivoand to Hypoxia and Glucose Deprivation in Cell Culture: Involvement of Perturbed Calcium Homeostasis

Mattson, M. P., Zhu, H., Yu, J., & Kindy, M. S. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-04-01358.2000 · Cited by 172 · see citing works

Inflammasomes: sensors of metabolic stresses for vascular inflammation

Yang, X.-F. (2013) · Frontiers in Bioscience · doi:10.2741/4127 · Cited by 134 · see citing works

Inhibition of autophagy induces IL-1β release from ARPE-19 cells via ROS mediated NLRP3 inflammasome activation under high glucose stress

Shi, H., Zhang, Z., Wang, X., Li, R., Hou, W., Bi, W., & Zhang, X. (2015) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2015.06.060 · Cited by 132 · see citing works

Production of Reactive Oxygen Species in the Diabetic Heart

Teshima, Y., Takahashi, N., Nishio, S., Saito, S., Kondo, H., Fukui, A., Aoki, K., Yufu, K., Nakagawa, M., & Saikawa, T. (2013) · Circulation Journal · doi:10.1253/circj.cj-13-1187 · Cited by 130 · see citing works

High Glucose and Lipopolysaccharide Prime NLRP3 Inflammasome via ROS/TXNIP Pathway in Mesangial Cells

Feng, H., Gu, J., Gou, F., Huang, W. G., Gao, C., Chen, G., Long, Y., Zhou, X., Yang, M., Liu, S., et al. (2016) · Journal of Diabetes Research · doi:10.1155/2016/6973175 · Cited by 128 · see citing works

Enhancement of Autophagy by Simvastatin through Inhibition of Rac1-mTOR Signaling Pathway in Coronary Arterial Myocytes

Wei, Y.-M., Li, X., Xu, M., Abais, J. M., Chen, Y., Riebling, C. R., Boini, K. M., Li, P., & Zhang, Y. (2013) · Cellular Physiology and Biochemistry · doi:10.1159/000350111 · Cited by 126 · see citing works

Activation of Nlrp3 Inflammasomes Enhances Macrophage Lipid-Deposition and Migration: Implication of a Novel Role of Inflammasome in Atherogenesis

Li, X., Zhang, Y., Xia, M., Gulbins, E., Boini, K. M., & Li, P. (2014) · PLoS ONE · doi:10.1371/journal.pone.0087552 · Cited by 116 · see citing works

Acid Sphingomyelinase and Its Redox Amplification in Formation of Lipid Raft Redox Signaling Platforms in Endothelial Cells

Zhang, A. Y., Yi, F., Jin, S., Xia, M., Chen, Q., Gulbins, E., & Li, P. (2007) · Antioxidants and Redox Signaling · doi:10.1089/ars.2007.1509 · Cited by 116 · see citing works

Endothelial NLRP3 Inflammasome Activation and Enhanced Neointima Formation in Mice by Adipokine Visfatin

Xia, M., Boini, K. M., Abais, J. M., Xu, M., Zhang, Y., & Li, P.-L. (2014) · The American Journal of Pathology · doi:10.1016/j.ajpath.2014.01.032 · Cited by 106 · see citing works

Endothelial Nlrp3 inflammasome activation associated with lysosomal destabilization during coronary arteritis

Chen, Y., Li, X., Boini, K. M., Pitzer, A. L., Gulbins, E., Zhang, Y., & Li, P. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2014.11.012 · Cited by 105 · see citing works

Coronary Endothelial Dysfunction Induced by Nucleotide Oligomerization Domain-Like Receptor Protein with Pyrin Domain Containing 3 Inflammasome Activation During Hypercholesterolemia: Beyond Inflammation

Zhang, Y., Li, X., Pitzer, A. L., Chen, Y., Wang, L., & Li, P. (2015) · Antioxidants and Redox Signaling · doi:10.1089/ars.2014.5978 · Cited by 90 · see citing works

HMGB1 Increases Permeability of the Endothelial Cell Monolayer via RAGE and Src Family Tyrosine Kinase Pathways

Huang, W., Liu, Y., Li, L., Zhang, R., Liu, W., Wu, J., Mao, E., & Tang, Y.-Q. (2011) · Inflammation · doi:10.1007/s10753-011-9325-5 · Cited by 83 · see citing works

Regulation of <scp>NOD</scp>‐like receptors and inflammasome activation in cerebral endothelial cells

Nagyőszi, P., Nyúl‐Tóth, Á., Fazakas, C., Wilhelm, I., Kozma, M., Molnár, J., Haskó, J., & Krizbai, I. A. (2015) · Journal of Neurochemistry · doi:10.1111/jnc.13197 · Cited by 82 · see citing works

Defective autophagosome trafficking contributes to impaired autophagic flux in coronary arterial myocytes lacking CD38 gene

Zhang, Y., Xu, M., Xia, M., Li, X., Boini, K. M., Wang, M., Gulbins, E., Ratz, P. H., & Li, P. (2014) · Cardiovascular Research · doi:10.1093/cvr/cvu011 · Cited by 49 · see citing works

Molecular and clinical aspects of endothelial dysfunction in diabetes

Nacci, C., Tarquinio, M., & Montagnani, M. (2009) · Internal and Emergency Medicine · doi:10.1007/s11739-009-0234-7 · Cited by 36 · see citing works

Albumin impairs renal tubular tight junctions via targeting the NLRP3 inflammasome.

Zhuang, Y.-B., Hu, C., Ding, G., Zhang, Y., Huang, S., Jia, Z., & Zhang, A.-H. (2015) · AJP - Renal Physiology · doi:10.1152/ajprenal.00509.2014 · Cited by 35 · see citing works

The mitochondrial Na(+)/Ca(2+) exchanger may reduce high glucose-induced oxidative stress and nucleotide-binding oligomerization domain receptor 3 inflammasome activation in endothelial cells.

Zu, Y., Wan, L.-J., Cui, S., Gong, Y., & Li, C. (2015) · Europe PMC (PubMed Central) · doi:10.11909/j.issn.1671-5411.2015.03.003 · Cited by 21 · see citing works

Trimethylamine‐N‐Oxide Induces Vascular Inflammation by Activating the NLRP3 Inflammasome Through the SIRT3‐SOD2‐mtROS Signaling Pathway

Chen, M., Zhu, X., Ran, L., Lang, H., Yi, L., & Mi, M. (2017) · Journal of the American Heart Association · doi:10.1161/jaha.117.006347 · Cited by 600 · see citing works

NLRP3 inflammasome in endothelial dysfunction

Bai, B., Yang, Y., Wang, Q., Li, M., Tian, C., Liu, Y., Aung, L. H. H., Li, P., Yu, T., & Chu, X. (2020) · Cell Death and Disease · doi:10.1038/s41419-020-02985-x · Cited by 492 · see citing works

Role of inflammation, immunity, and oxidative stress in hypertension: New insights and potential therapeutic targets

Zhang, Z., Zhao, L. Q., Zhou, X., Meng, X., & Zhou, X. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1098725 · Cited by 387 · see citing works

Trimethylamine-N-Oxide Instigates NLRP3 Inflammasome Activation and Endothelial Dysfunction

Boini, K. M., Hussain, T., Li, P.-L., & Koka, S. S. (2017) · Cellular Physiology and Biochemistry · doi:10.1159/000484623 · Cited by 302 · see citing works

NLRP3 inflammasome pathways in atherosclerosis

Baldrighi, M., Mallat, Z., & Li, X. (2017) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2017.10.027 · Cited by 202 · see citing works

The role of inflammasomes in vascular cognitive impairment

Poh, L., Sim, W. L., Jo, D., Dinh, Q. N., Drummond, G. R., Sobey, C. G., Chen, C., Lai, M. K. P., Fann, D. Y., & Arumugam, T. V. (2022) · Molecular Neurodegeneration · doi:10.1186/s13024-021-00506-8 · Cited by 167 · see citing works

NLRP3 Inflammasome at the Interface of Inflammation, Endothelial Dysfunction, and Type 2 Diabetes

Góra, I. M., Ciechanowska, A., & Ładyżyński, P. (2021) · Cells · doi:10.3390/cells10020314 · Cited by 150 · see citing works

The mechanisms of NLRP3 inflammasome/pyroptosis activation and their role in diabetic retinopathy

Zheng, X., Wan, J., & Tan, G. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1151185 · Cited by 146 · see citing works

Induction of NLRP3 Inflammasome Activation by Heme in Human Endothelial Cells

Erdei, J., Tóth, A., Balogh, E., Nyakundi, B. B., Bányai, E., Ryffel, B., Paragh, G., Cordero, M. D., & Jeney, V. (2018) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2018/4310816 · Cited by 120 · see citing works

Mitochondria, the NLRP3 Inflammasome, and Sirtuins in Type 2 Diabetes: New Therapeutic TargetsReviewing Editors: Markus Bachschmid, Dylan Burger, Vittorio Calabrese, Amadou Camara, Lukas Kubala, Giuseppe Poli, and Chandan K. Sen

Rovira‐Llopis, S., Apostolova, N., Bañuls, C., Muntané, J., Rocha, M., & Víctor, V. M. (2017) · Antioxidants and Redox Signaling · doi:10.1089/ars.2017.7313 · Cited by 120 · see citing works

Cardiovascular protection by SGLT2 inhibitors – Do anti-inflammatory mechanisms play a role?

Elrakaybi, A., Laubner, K., Zhou, Q., Hug, M. J., & Seufert, J. (2022) · Molecular Metabolism · doi:10.1016/j.molmet.2022.101549 · Cited by 114 · see citing works

Inflammation in Metabolic Cardiomyopathy

Wenzl, F. A., Ambrosini, S., Mohammed, S. A., Kraler, S. C., Lüscher, T. F., Costantino, S., & Paneni, F. (2021) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.742178 · Cited by 109 · see citing works

Aspirin alleviates endothelial gap junction dysfunction through inhibition of NLRP3 inflammasome activation in LPS-induced vascular injury

Zhou, X., Wu, Y., Ye, L., Wang, Y., Zhang, K., Wang, L., Huang, Y., Wang, L., Xian, S., Zhang, Y., et al. (2019) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2019.02.008 · Cited by 107 · see citing works

High Mobility Group Box 1 Mediates TMAO-Induced Endothelial Dysfunction

Singh, G. B., Zhang, Y., Boini, K. M., & Koka, S. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20143570 · Cited by 102 · see citing works

Role of Inflammasomes in Kidney Diseases via Both Canonical and Non-canonical Pathways

Xiang, H., Zhu, F., Xu, Z., & Xiong, J. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00106 · Cited by 94 · see citing works

Puerarin inhibits hyperglycemia-induced inter-endothelial junction through suppressing endothelial Nlrp3 inflammasome activation via ROS-dependent oxidative pathway

Lian, D., Yuan, H., Yin, X.-Z., Wu, Y., He, R., Huang, Y., & Chen, Y. (2018) · Phytomedicine · doi:10.1016/j.phymed.2018.10.013 · Cited by 92 · see citing works

Knockdown of NLRP3 alleviates high glucose or TGFB1-induced EMT in human renal tubular cells

Song, S., Qiu, D., Luo, F., Wei, J., Wu, M. T., Wu, H., Du, C., Du, Y., Ren, Y., Chen, N., et al. (2018) · Journal of Molecular Endocrinology · doi:10.1530/jme-18-0069 · Cited by 89 · see citing works

Mitochondrial Oxidative Stress in Brain Microvascular Endothelial Cells: Triggering Blood-Brain Barrier Disruption.

Wang, Y., Wu, J., Wang, J.-X., He, L.-X., Lai, H., Zhang, T., Wang, X., & Li, W. (2023) · Mitochondrion (Amsterdam. Print) · doi:10.1016/j.mito.2023.01.007 · Cited by 80 · see citing works

Periodontal ligament fibroblasts migration injury via ROS/TXNIP/Nlrp3 inflammasome pathway with Porphyromonas gingivalis lipopolysaccharide

Lian, D., Dai, L., Xie, Z., Zhou, X., Liu, X., Zhang, Y., Huang, Y., & Chen, Y. (2018) · Molecular Immunology · doi:10.1016/j.molimm.2018.10.001 · Cited by 82 · see citing works

Downregulation of hsa_circ_0068087 ameliorates TLR4/NF-κB/NLRP3 inflammasome-mediated inflammation and endothelial cell dysfunction in high glucose conditioned by sponging miR-197

Cheng, J., Liu, Q., Hu, N., Zheng, F., Zhang, X., Ni, Y., & Liu, J. (2019) · Gene · doi:10.1016/j.gene.2019.05.012 · Cited by 79 · see citing works

NLRP3 Activation and Its Relationship to Endothelial Dysfunction and Oxidative Stress: Implications for Preeclampsia and Pharmacological Interventions

Nunes, P. R., Viana-Mattioli, S., & Sandrim, V. C. (2021) · Cells · doi:10.3390/cells10112828 · Cited by 73 · see citing works

Melatonin attenuates smoking-induced atherosclerosis by activating the Nrf2 pathway via NLRP3 inflammasomes in endothelial cells

Zhao, Z., Wang, X., Zhang, R., Ma, B., Niu, S., Di, X., Ni, L., & Liu, C. (2021) · Aging · doi:10.18632/aging.202829 · Cited by 68 · see citing works

Cardiovascular diseases, NLRP3 inflammasome, and western dietary patterns

Pavillard, L. E., Marín‐Aguilar, F., Bullón, P., & Cordero, M. D. (2018) · Pharmacological Research · doi:10.1016/j.phrs.2018.03.018 · Cited by 66 · see citing works

Contribution of cathepsin B-dependent Nlrp3 inflammasome activation to nicotine-induced endothelial barrier dysfunction

Zhang, Y., Chen, Y., Zhang, Y., Li, P., & Li, X. (2019) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2019.172795 · Cited by 66 · see citing works

Cellular Stress and General Pathological Processes

Gusev, E. Y., & Zotova, N. V. (2019) · Current Pharmaceutical Design · doi:10.2174/1381612825666190319114641 · Cited by 58 · see citing works

NLRP3 Inflammasome Formation and Activation in Nonalcoholic Steatohepatitis: Therapeutic Target for Antimetabolic Syndrome Remedy FTZ

Chen, Y., He, X., Yuan, X., Hong, J., Bhat, O. M., Li, G., Li, P., & Guo, J. (2018) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2018/2901871 · Cited by 56 · see citing works

Neutrophil microparticle production and inflammasome activation by hyperglycemia due to cytoskeletal instability

Thom, S. R., Bhopale, V. M., Yu, K., Huang, W., Kane, M. A., & Margolis, D. J. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.m117.802629 · Cited by 55 · see citing works

Diabetes Induces Abnormal Ovarian Function via Triggering Apoptosis of Granulosa Cells and Suppressing Ovarian Angiogenesis

Wu, Y., Li, Y., Liao, X., Wang, Z., Li, R., Zou, S., Jiang, T., Zheng, B., Duan, P., & Xiao, J. (2017) · International Journal of Biological Sciences · doi:10.7150/ijbs.21172 · Cited by 55 · see citing works

Rosmarinic acid inhibits oxLDL-induced inflammasome activation under high-glucose conditions through downregulating the p38-FOXO1-TXNIP pathway

Nyandwi, J. B., Ko, G. H., Jin, H., Yun, S. P., Park, S. W., & Kim, H. J. (2020) · Biochemical Pharmacology · doi:10.1016/j.bcp.2020.114246 · Cited by 54 · see citing works

Caspase-1 has a critical role in blood-brain barrier injury and its inhibition contributes to multifaceted repair

Israelov, H., Ravid, O., Atrakchi, D., Rand, D., Goldman, S. E., Bresler, Y., Twitto‐Greenberg, R., Omesi, L., Zaltsman, S. L., Gosselet, F., et al. (2020) · Journal of Neuroinflammation · doi:10.1186/s12974-020-01927-w · Cited by 53 · see citing works

Dysregulation of the NLRP3 Inflammasome in Diabetic Retinopathy and Potential Therapeutic Targets

Raman, K. S., & Matsubara, J. A. (2020) · Ocular Immunology and Inflammation · doi:10.1080/09273948.2020.1811350 · Cited by 52 · see citing works

Protective effects of acarbose against vascular endothelial dysfunction through inhibiting Nox4/NLRP3 inflammasome pathway in diabetic rats

Li, X.-X., Ling, S., Hu, M., Ma, Y., Li, Y., & Huang, P. (2019) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2019.09.015 · Cited by 51 · see citing works

Advances in treatment strategies based on scavenging reactive oxygen species of nanoparticles for atherosclerosis

Wu, C., Mao, J., Wang, X., Yang, R., Wang, C., Li, C., & Zhou, X. (2023) · Journal of Nanobiotechnology · doi:10.1186/s12951-023-02058-z · Cited by 44 · see citing works

Hepatic small extracellular vesicles promote microvascular endothelial hyperpermeability during NAFLD via novel-miRNA-7

Zuo, R. M., Ye, L.-F., Huang, Y., Song, Z., Wang, L., Zhi, H., Zhang, M., Li, J.-Y., Zhu, L., Xiao, W., et al. (2021) · Journal of Nanobiotechnology · doi:10.1186/s12951-021-01137-3 · Cited by 44 · see citing works

Extracellular Histones Activate Endothelial NLRP3 Inflammasome and are Associated with a Severe Sepsis Phenotype

Beltrán-García, J., Osca-Verdegal, R., Pérez‐Cremades, D., Novella, S., Hermenegildo, C., Pallardó, F. V., & García‐Giménez, J. L. (2022) · Journal of Inflammation Research · doi:10.2147/jir.s363693 · Cited by 44 · see citing works

Pyroptosis and Its Regulation in Diabetic Cardiomyopathy

Lu, Y., Lu, Y., Meng, J., & Wang, Z. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2021.791848 · Cited by 43 · see citing works

The Role of NLRP3 Inflammasome in Diabetic Cardiomyopathy and Its Therapeutic Implications

Ding, K., Song, C., Hu, H.-J., Yin, K., Huang, H., & Tang, H. (2022) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2022/3790721 · Cited by 40 · see citing works

HMGB1 signaling pathway in diabetes-related dementia: Blood-brain barrier breakdown, brain insulin resistance, and Aβ accumulation

Jeong, J., Lee, D. H., & Song, J. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.112933 · Cited by 39 · see citing works

The IL-1 family of cytokines. Do they have a role in scleroderma fibrosis?

Artlett, C. M. (2017) · Immunology Letters · doi:10.1016/j.imlet.2017.11.012 · Cited by 39 · see citing works

HMGB1 plays an important role in pyroptosis induced blood brain barrier breakdown in diabetes-associated cognitive decline

Liu, L., Wang, N., Kalionis, B., Xia, S., & He, Q. (2021) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2021.577763 · Cited by 38 · see citing works

Regulation of Staphylococcus aureus Infection of Macrophages by CD44, Reactive Oxygen Species, and Acid Sphingomyelinase

Li, C., Wu, Y., Riehle, A., Orian‐Rousseau, V., Zhang, Y., Gulbins, E., & Grassmé, H. (2017) · Antioxidants and Redox Signaling · doi:10.1089/ars.2017.6994 · Cited by 39 · see citing works

Protection by simvastatin on hyperglycemia-induced endothelial dysfunction through inhibiting NLRP3 inflammasomes

Lv, Z.-H., Phuong, T. A., Jin, S., Li, X.-X., & Xu, M. (2017) · Oncotarget · doi:10.18632/oncotarget.20443 · Cited by 36 · see citing works

Cathepsin B-Mediated NLRP3 Inflammasome Formation and Activation in Angiotensin II -Induced Hypertensive Mice: Role of Macrophage Digestion Dysfunction

Lian, D., Lai, J., Wu, Y., Wang, L., Chen, Y., Zhang, Y., Boini, K. M., Huang, Y., & Chen, Y. (2018) · Cellular Physiology and Biochemistry · doi:10.1159/000494656 · Cited by 36 · see citing works

Involvement of Nucleotide-Binding Oligomerization Domain-Like Receptor Family Pyrin Domain Containing 3 Inflammasome in the Pathogenesis of Liver Diseases

Shi, C., Yang, H., & Zhang, Z. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00139 · Cited by 34 · see citing works

Aloe emodin relieves Ang II-induced endothelial junction dysfunction via promoting ubiquitination mediated NLRP3 inflammasome inactivation

Zhang, Y., Song, Z., Huang, S., Zhu, L., Liu, T., Shu, H., Wang, L., Huang, Y., & Chen, Y. (2020) · Journal of Leukocyte Biology · doi:10.1002/jlb.3ma0520-582r · Cited by 34 · see citing works

Crosstalk Between Acid Sphingomyelinase and Inflammasome Signaling and Their Emerging Roles in Tissue Injury and Fibrosis

Li, C., Guo, S., Pang, W., & Zhao, Z. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2019.00378 · Cited by 33 · see citing works

The Role of NLRP3 Inflammasome in Radiation-Induced Cardiovascular Injury

Huang, S., Che, J., Chu, Q., & Zhang, P. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00140 · Cited by 33 · see citing works

Unravelling myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): Gender‐specific changes in the microRNA expression profiling in ME/CFS

Cheema, A. K., Sarría, L., Bekheit, M., Collado, F., Almenar‐Pérez, E., Martín‐Martínez, E., Alegre, J., Castro‐Marrero, J., FLETCHER, M. A., Klimas, N. G., et al. (2020) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.15260 · Cited by 31 · see citing works

Skeletal Muscle Microvascular Dysfunction in Obesity-Related Insulin Resistance: Pathophysiological Mechanisms and Therapeutic Perspectives

Ugwoke, C. K., Cvetko, E., & Umek, N. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23020847 · Cited by 35 · see citing works

Expression and Contribution of NLRP3 Inflammasome During the Follicular Development Induced by PMSG

Zhang, Z., Wang, F., & Zhang, Y. (2019) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2019.00256 · Cited by 30 · see citing works

Exosomes: Biomarkers and Therapeutic Targets of Diabetic Vascular Complications

Chen, A., Wang, H., Su, Y., Zhang, C., Qiu, Y., Zhou, Y., Wan, Y., Hu, B., & Li, Y. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.720466 · Cited by 31 · see citing works

AdipoRon Alleviates Free Fatty Acid-Induced Myocardial Cell Injury Via Suppressing Nlrp3 Inflammasome Activation

Zhang, Y., Zhang, Y.-L., Huang, Q., Huang, C., Jiang, Z., Cai, F., & Shen, J. (2019) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s221841 · Cited by 28 · see citing works

Lysosomal destabilization activates the NLRP3 inflammasome in human umbilical vein endothelial cells (HUVECs)

Kinnunen, K., Piippo, N., Loukovaara, S., Hytti, M., Kaarniranta, K., & Kauppinen, A. (2017) · Journal of Cell Communication and Signaling · doi:10.1007/s12079-017-0396-4 · Cited by 27 · see citing works

Endothelial acid ceramidase in exosome-mediated release of NLRP3 inflammasome products during hyperglycemia: Evidence from endothelium-specific deletion of Asah1 gene

Yuan, X., Bhat, O. M., Lohner, H., Zhang, Y., & Li, P. (2019) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2019.158532 · Cited by 27 · see citing works

The protective effects of orexin a against high glucose-induced activation of NLRP3 inflammasome in human vascular endothelial cells

Zhang, C., Abdukerim, M., Abilailieti, M., Tang, L., Ling, Y., & Pan, S. (2019) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2019.07.017 · Cited by 26 · see citing works

Simvastatin improves lysosome function via enhancing lysosome biogenesis in endothelial cells

Li, X. (2019) · Frontiers in bioscience · doi:10.2741/4807 · Cited by 26 · see citing works

Dihydromyricetin protects against high glucose-induced endothelial dysfunction: Role of HIF-1α/ROR2/NF-κB

Awad, E. M., Ahmed, A. F., El‐Daly, M., Amin, A. H., El‐Tahawy, N. F. G., Wagdy, A., Hollenberg, M. D., & Taye, A. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.113308 · Cited by 26 · see citing works

The Interaction of Gut Microbiota and Heart Failure with Preserved Ejection Fraction: From Mechanism to Potential Therapies

Yu, W., Jiang, Y., Xu, H., & Zhou, Y. (2023) · Biomedicines · doi:10.3390/biomedicines11020442 · Cited by 26 · see citing works

Recent Advances in Microbiota-Associated Metabolites in Heart Failure

Masenga, S., Povia, J. P., Lwiindi, P., & Kirabo, A. (2023) · Biomedicines · doi:10.3390/biomedicines11082313 · Cited by 28 · see citing works

Soluble uric acid induces inflammation via TLR4/NLRP3 pathway in intestinal epithelial cells.

Ma, C., Yang, X., Lv, Q., Yan, Z., Chen, Z., Xu, D., Liu, X., Yang, W. Q., & Xing, S. (2020) · PubMed Central · doi:10.22038/ijbms.2020.44948.10482 · Cited by 23 · see citing works

Ambroxol for the treatment of fibromyalgia: science or fiction?

Kern, K., & Schwickert, M. (2017) · Journal of Pain Research · doi:10.2147/jpr.s139223 · Cited by 21 · see citing works

Neutrophils Kill Reactive Oxygen Species-Resistant Pseudomonas aeruginosa by Sphingosine

Becker, K. A., Li, X., Seitz, A. P., Steinmann, J., Koch, A., Schuchman, E. H., Kamler, M., Edwards, M. J., Caldwell, C. C., & Gulbins, E. (2017) · Cellular Physiology and Biochemistry · doi:10.1159/000482024 · Cited by 19 · see citing works

Canagliflozin inhibits inflammasome activation in diabetic endothelial cells – Revealing a novel calcium-dependent anti-inflammatory effect of canagliflozin on human diabetic endothelial cells

Li, X., Kerindongo, R. P., Preckel, B., Kalina, J.-O., Hollmann, M. W., Zuurbier, C. J., & Weber, N. C. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.114228 · Cited by 17 · see citing works

What type of cell death occurs in chronic cerebral hypoperfusion? A review focusing on pyroptosis and its potential therapeutic implications

He, Y., Chen, X., Wu, M., Hou, X., & Zhou, Z. (2023) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2023.1073511 · Cited by 18 · see citing works

Endothelial Dysfunction in Type 2 Diabetes: Targeting Inflammation

Sena, C. M., Carrilho, F., & Seiça, R. M. F. (2018) · InTech eBooks · doi:10.5772/intechopen.76994 · Cited by 17 · see citing works

Downregulation of Lysosomal Acid Ceramidase Mediates HMGB1-Induced Migration and Proliferation of Mouse Coronary Arterial Myocytes

Yuan, X., Bhat, O. M., Lohner, H., Zhang, Y., & Li, P. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00111 · Cited by 17 · see citing works

Pelargonic acid vanillylamide and rosuvastatin protect against oxidized low-density lipoprotein-induced endothelial dysfunction by inhibiting the NF-κB/NLRP3 pathway and improving cell-cell junctions

Sivasinprasasn, S., Wikan, N., Tocharus, J., Chaichompoo, W., Suksamrarn, A., & Tocharus, C. (2021) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2021.109572 · Cited by 17 · see citing works

Tricyclic antidepressant amitriptyline inhibits autophagic flux and prevents tube formation in vascular endothelial cells

Guan, Y., Li, X., Umetani, M., Boini, K. M., Li, P., & Zhang, Y. (2018) · Basic & Clinical Pharmacology & Toxicology · doi:10.1111/bcpt.13146 · Cited by 16 · see citing works

The involvement of autophagy in the maintenance of endothelial homeostasis: The role of mitochondria

Dymkowska, D. (2021) · Mitochondrion · doi:10.1016/j.mito.2020.12.013 · Cited by 15 · see citing works

The Application of Functional Magnetic Resonance Imaging in Type 2 Diabetes Rats With Contrast-Induced Acute Kidney Injury and the Associated Innate Immune Response

Li, Y., Shi, D., Zhang, H., Yao, X., Wang, S., Wang, R., & Ren, K. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.669581 · Cited by 16 · see citing works

Role of Trimethylamine N-Oxide in Heart Failure

Jing, L., Zhang, H., Xiang, Q., Hu, H., Zhai, C., Xu, S., & Tian, H. (2024) · Reviews in Cardiovascular Medicine · doi:10.31083/j.rcm2507240 · Cited by 15 · see citing works

The effect of A1 adenosine receptor in diabetic megalin loss with caspase-1/IL18 signaling

Tian, D., Shi, X., Zhao, Y., Peng, X., Zou, L., Xu, L., Ma, Y., Wen, Y., Faulhaber‐Walter, R., & Chen, L. (2019) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s215531 · Cited by 14 · see citing works

Role of Fluid Milk in Attenuating Postprandial Hyperglycemia and Hypertriglyceridemia

Leary, M. P., & Tanaka, H. (2020) · Nutrients · doi:10.3390/nu12123806 · Cited by 14 · see citing works

Kakonein restores diabetes‐induced endothelial junction dysfunction via promoting autophagy‐mediated NLRP 3 inflammasome degradation

Lian, D., Liu, J., Han, R., Jin, J., Zhu, L., Zhang, Y., Huang, Y., Wang, X., Xian, S., & Chen, Y. (2021) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.16747 · Cited by 13 · see citing works

Expression and diagnostic value of lncRNA MALAT1 and NLRP3 in lower limb atherosclerosis in diabetes

Li, J., Wang, C., Shao, C., & Xu, J. (2024) · BMC Endocrine Disorders · doi:10.1186/s12902-024-01557-w · Cited by 12 · see citing works

Coronary Microvascular Dysfunction Is Associated With Augmented Lysosomal Signaling in Hypercholesterolemic Mice

Wang, Y., Moura, A. K., Zuo, R. M., Zhou, W., Wang, Z., Roudbari, K., Hu, J. Z., Li, P., Zhang, Y., & Li, X. (2024) · Journal of the American Heart Association · doi:10.1161/jaha.124.037460 · Cited by 12 · see citing works

The synergistic effect of 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-glucoside combined with Adriamycin on MCF-7 breast cancer cells

Shen, J., Zhang, Y., Shen, H., Pan, H., Xu, L., Yuan, L., & Ding, Z. (2018) · Drug Design Development and Therapy · doi:10.2147/dddt.s186028 · Cited by 10 · see citing works

The Protective Role of Interleukin-37 in Cardiovascular Diseases through Ferroptosis Modulation

Cruz‐Gregorio, A., Amezcua-Guerra, L. M., Fisher-Bautista, B., Romero-Beltrán, A., & Fonseca‐Camarillo, G. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25189758 · Cited by 9 · see citing works

Gut Microbiota and Short-Chain Fatty Acids in Cardiometabolic HFpEF: Mechanistic Pathways and Nutritional Therapeutic Perspectives

Vacca, A., Brosolo, G., Marcante, S., Mora, S. D., Bulfone, L., Porto, A. D., Pagano, C., Catena, C., & Sechi, L. A. (2026) · Nutrients · doi:10.3390/nu18020321 · Cited by 11 · see citing works

Gallic acid rescues uranyl acetate induced-hepatic dysfunction in rats by its antioxidant and cytoprotective potentials

Elmileegy, I. M. H., Waly, H. S. A., Alghriany, A. A. I., Khalil, N. S. A., Mahmoud, S. M. M., & Negm, E. (2023) · BMC Complementary Medicine and Therapies · doi:10.1186/s12906-023-04250-y · Cited by 9 · see citing works

The study of the mechanism of non-coding RNA regulation of programmed cell death in diabetic cardiomyopathy

Zhang, B., Wu, H., Zhang, J., Cong, C., & Zhang, L. (2024) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-023-04909-7 · Cited by 9 · see citing works

NLRP3 sparks the Greek fire in the war against lipid‐related diseases

Jiang, S., Xiao, H., Wu, Z. B., Yang, Z. P., Ding, B., Jin, Z., & Yang, Y. (2020) · Obesity Reviews · doi:10.1111/obr.13045 · Cited by 9 · see citing works

Imbalance in thioredoxin system activates NLRP3 inflammasome pathway in epicardial adipose tissue of patients with coronary artery disease

Shateri, H., Manafi, B., Tayebinia, H., Karimi, J., & Khodadadi, I. (2021) · Molecular Biology Reports · doi:10.1007/s11033-021-06208-0 · Cited by 9 · see citing works

Unveiling the role of PD-L1 in vascular endothelial dysfunction: Insights into the mtros/NLRP3/caspase-1 mediated pyroptotic pathway

Tao, T., Zhu, Y., Shi, Y., Sun, B., Gu, Y. B., & Xu, S. (2024) · Experimental Cell Research · doi:10.1016/j.yexcr.2024.114047 · Cited by 8 · see citing works

Histomorphological, VEGF and TGF-β immunoexpression changes in the diabetic rats’ ovary and the potential amelioration following treatment with metformin and insulin

Ali, E., Abdallah, H. I., & El-Sayed, S. (2020) · Journal of Molecular Histology · doi:10.1007/s10735-020-09880-x · Cited by 8 · see citing works

Kakonein restores hyperglycemia-induced macrophage digestion dysfunction through regulation of cathepsin B-dependent NLRP3 inflammasome activation

Lian, D., Zhu, L., Yu, Y., Zhang, X., Lin, Y.-K., Liu, J., Han, R., Guo, Y., Cai, D., Xiao, W., et al. (2022) · Journal of Leukocyte Biology · doi:10.1002/jlb.3ma0821-418r · Cited by 7 · see citing works

Vitamin C and the management of diabetic foot ulcers: a literature review

Tong, K. P. S., Intine, R. V. A., & Wu, S. (2022) · Journal of Wound Care · doi:10.12968/jowc.2022.31.sup9.s33 · Cited by 7 · see citing works

miR-138-5p ameliorates intestinal barrier disruption caused by acute superior mesenteric vein thrombosis injury by inhibiting the NLRP3/HMGB1 axis

Li, Y., Ling, P., Li, Y., Wang, Y., Li, G., Qiu, C., Wang, J., & Gong, K. (2024) · PeerJ · doi:10.7717/peerj.16692 · Cited by 6 · see citing works

Exosomal novel-miRNA-126 mediates vascular endothelial dysfunction by targeting AhR-NLRP3 pathway in nonalcoholic steatohepatitis

Chen, Q., Ye, L., Huang, L., You, H., Yu, X., Wang, K., Xiong, S., Liao, W., Wang, X., Li, H., et al. (2025) · Scientific Reports · doi:10.1038/s41598-025-94917-y · Cited by 5 · see citing works

Impairment of Ceramide-Mediated Endothelial Instant Membrane Resealing During Diabetes Mellitus

Chen, Y., Li, G., Bhat, O. M., Li, X., Zhang, Y., & Li, P. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.910339 · Cited by 5 · see citing works

Contribution of NLRP3-GSDMD axis to PDGF-BB-induced vascular smooth muscle cell phenotypic transition

Wang, Y., Moura, A. K., Zuo, R. M., Guan, Y., Lee, E. A., Hu, J. Z., Roudbari, K., Wang, Z., Wang, M., Li, P., et al. (2025) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00226.2025 · Cited by 4 · see citing works

NLRP3 targets HMGB1 to exacerbate the pyroptosis of canine corneal epithelial cells infected with Staphylococcus pseudintermedius

Wang, Z., Guo, L., Zhu, C., Li, J., Guo, J., Zhu, X., Li, J., Cui, L., Dong, J., Liu, K., et al. (2024) · Experimental Eye Research · doi:10.1016/j.exer.2024.110096 · Cited by 4 · see citing works

Rickettsia disrupts and reduces endothelial tight junction protein zonula occludens-1 in association with inflammasome activation

Velatooru, L. R., Arroyave, E., Rippee‐Brooks, M. D., Burch, M., Yang, E., Zhu, B. D., Walker, D. H., Zhang, Y., & Fang, R. (2024) · Infection and Immunity · doi:10.1128/iai.00468-24 · Cited by 3 · see citing works

Novel Optical Imaging Probe for the Targeted Visualization of NLRP3 Inflammasomes in Living Retina

Uddin, M. I., Dieckmann, B. W., & Soliman, S. (2025) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.5c00999 · Cited by 3 · see citing works

RAGE Axis in the Pathogenesis and Treatment of CNS Neurodegeneration in Long-Term Hyperglycemia

Wasilewska, B., Mazur, U., Kordas, B., Mizia, P., & Juranek, J. K. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27041881 · Cited by 2 · see citing works

Innate Immunity and Inflammation: The Molecular Mechanisms Governing the Cross-Talk Between Innate Immune and Endothelial Cells

Boff, D., Fagundes, C. T., Russo, R. C., & Amaral, F. A. (2018) · Springer eBooks · doi:10.1007/978-3-319-77658-3_2 · Cited by 2 · see citing works

Circulating HMGB2 Is Associated With Angiographic Coronary Collateralization in Diabetic Patients With Chronic Total Occlusion and Impairs Vessel Growth via NLRP3

Wu, Z. M., Chen, S., Dai, Y., Huang, K. Q., Wang, X. Q., Mao, L. S., Yang, C. D., Li, F. F., Li, L. Y., Liu, J. M., et al. (2025) · Circulation Journal · doi:10.1253/circj.cj-24-0878 · Cited by 1 · see citing works

Association between serum uric acid to high-density lipoprotein ratio and all-cause in hypertensive patients: Mediating role of neutrophils

Yan, C., Zhou, Y., Wang, H., Fu, J., & Xu, Q. (2025) · PLoS ONE · doi:10.1371/journal.pone.0325620 · Cited by 1 · see citing works

Human umbilical cord mesenchymal stem cells secretome and nanoemulsion propolis combination ameliorate osteoclastogenesis in lipopolysaccharide-induced osteolysis in hyperglycemia rats

Nugraha, A. P., Yang, K., Pramusita, A., Putranti, N. A. R., Luthfi, M., Ramadhani, N. F., Sitalaksmi, R. M., Situmorang, P. C., Artasasta, M. A., Alhasyimi, A. A., et al. (2025) · Journal of Dental Sciences · doi:10.1016/j.jds.2025.07.003 · Cited by 2 · see citing works

Endothelial Dysfunction in Vascular Inflammation: The Role of NLRP3, NLRP10, AIM2, TLR9, and PANoptosis

Silva‐Velasco, D. L., dos Passos, R. R., Moraes, R. A., Gonçalves, T. T., Wilczynski, S., Zhang, T., Randar, S., Tobin, J. K., Uline, M. J., Priviero, F. B. M., et al. (2026) · Handbook of experimental pharmacology · doi:10.1007/164_2026_802 · Cited by 1 · see citing works

NLRP3 Inflammasome at the Interface of Inflammation, Endothelial Dysfunction, and Type 2 Diabetes

Góra, I. M., Ciechanowska, A., & Ładyżyński, P. (2021) · Cells · doi:10.3390/cells10020314 · Cited by 150 · see citing works

Mitochondrial DNA Promotes NLRP3 Inflammasome Activation and Contributes to Endothelial Dysfunction and Inflammation in Type 1 Diabetes

Pereira, C. A., Carlos, D., Ferreira, N. S., da Silva, J. F., Zanotto, C. Z., Zamboni, D. S., Garcia, V. D., Ventura, D. F., Silva, J. S., & Tostes, R. C. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2019.01557 · Cited by 86 · see citing works

NLRP3 inflammasome promotes diabetes-induced endothelial inflammation and atherosclerosis

Wan, Z., Yang, F., Liu, X., Xue, J., Zhou, H., Zhu, C., & Wang, X. (2019) · DOAJ (DOAJ: Directory of Open Access Journals) · Cited by 10 · see citing works

Abstract 031: Novel Role of Nlrp3 Inflammasome Activation beyond Canonical Inflammation: Coronary Endothelial Injury and Repair

Zhang, Y., Xia, M., Chen, Y., Pitzer, A. L., Li, X., Boini, K. M., & Li, P. (2014) · Hypertension · doi:10.1161/hyp.64.suppl_1.031

A novel mechanism of diabetic vascular endothelial dysfunction: Hypoadiponectinemia-induced NLRP3 inflammasome activation

Zhang, J., Xia, L., Zhang, F., Zhu, D., Xin, C., Wang, H., Zhang, F., Guo, X., Lee, Y., Zhang, L., et al. (2017) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2017.02.012 · Cited by 64 · see citing works