Missing Pieces in the NF-κB Puzzle

A Toll-like receptor recognizes bacterial DNA

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Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3

Alexopoulou, L., Holt, A. C., Medzhitov, R., & Flavell, R. A. (2001) · Nature · doi:10.1038/35099560 · Cited by 6,129 · see citing works

NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses

Ghosh, S., May, M. J., & Kopp, E. B. (1998) · Annual Review of Immunology · doi:10.1146/annurev.immunol.16.1.225 · Cited by 5,182 · see citing works

Phosphorylation meets ubiquitination: the control of NF-κB activity

Karin, M., & Ben-Neriah, Y. (2000) · Annual Review of Immunology · doi:10.1146/annurev.immunol.18.1.621 · Cited by 4,766 · see citing works

NF-κB at the crossroads of life and death

Karin, M., & Lin, A. (2002) · Nature Immunology · doi:10.1038/ni0302-221 · Cited by 2,709 · see citing works

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

Wang, C., Deng, L., Hong, M., Akkaraju, G. R., Inoue, J.-I., & Chen, Z. J. (2001) · Nature · doi:10.1038/35085597 · Cited by 2,125 · see citing works

A cytokine-responsive IκB kinase that activates the transcription factor NF-κB

DiDonato, J. A., Hayakawa, M., Rothwarf, D. M., Zandi, E., & Karin, M. (1997) · Nature · doi:10.1038/41493 · Cited by 2,125 · see citing works

IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation

Mercurio, F., Zhu, H., Murray, B. W., Shevchenko, A., Bennett, B. L., Li, J. W., Young, D. B., Barbosa, M. S., Mann, M., Manning, A. M., et al. (1997) · Science · doi:10.1126/science.278.5339.860 · Cited by 2,042 · see citing works

Activation of the IκB Kinase Complex by TRAF6 Requires a Dimeric Ubiquitin-Conjugating Enzyme Complex and a Unique Polyubiquitin Chain

Deng, L., Wang, C., Spencer, E., Yang, L., Braun, A., You, J., Slaughter, C., Pickart, C., & Chen, Z. J. (2000) · Cell · doi:10.1016/s0092-8674(00)00126-4 · Cited by 1,872 · see citing works

Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand.

Kong, Y.-Y., Feige, U., Sarosi, I., Bolon, B., Tafuri, A., Morony, S., Capparelli, C., Li, J., Elliott, R., McCabe, S., et al. (1999) · Nature · doi:10.1038/46303 · Cited by 1,856 · see citing works

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

Beg, A. A., Sha, W. C., Bronson, R. T., Ghosh, S., & Baltimore, D. (1995) · Nature · doi:10.1038/376167a0 · Cited by 1,828 · see citing works

The IκB Kinase Complex (IKK) Contains Two Kinase Subunits, IKKα and IKKβ, Necessary for IκB Phosphorylation and NF-κB Activation

Zandi, E., Rothwarf, D. M., Delhase, M., Hayakawa, M., & Karin, M. (1997) · Cell · doi:10.1016/s0092-8674(00)80406-7 · Cited by 1,814 · see citing works

Requirement for glycogen synthase kinase-3β in cell survival and NF-κB activation

Hoeflich, K. P., Luo, J., Rubie, E. A., Tsao, M., Jin, O., & Woodgett, J. R. (2000) · Nature · doi:10.1038/35017574 · Cited by 1,394 · see citing works

Activation by IKKα of a Second, Evolutionary Conserved, NF-κB Signaling Pathway

Senftleben, U., Cao, Y., Xiao, G., Greten, F. R., Krähn, G. M., Bonizzi, G., Chen, Y., Hu, Y., Fong, A., Sun, S., et al. (2001) · Science · doi:10.1126/science.1062677 · Cited by 1,361 · see citing works

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

Fitzgerald, K. A., Pålsson‐McDermott, E. M., Bowie, A., Jefferies, C. A., Mansell, A. S., Brady, G., Brint, E. K., Dunne, A., Gray, P., Harte, M. T., et al. (2001) · Nature · doi:10.1038/35092578 · Cited by 1,258 · see citing works

Duration of Nuclear NF-κB Action Regulated by Reversible Acetylation

Chen, L., Fischle, W., Verdin, E. M., & Greene, W. C. (2001) · Science · doi:10.1126/science.1062374 · Cited by 1,231 · see citing works

Phosphorylation of NF-κB p65 by PKA Stimulates Transcriptional Activity by Promoting a Novel Bivalent Interaction with the Coactivator CBP/p300

Zhong, H., Voll, R. E., & Ghosh, S. (1998) · Molecular Cell · doi:10.1016/s1097-2765(00)80066-0 · Cited by 1,210 · see citing works

IκB Kinase-β: NF-κB Activation and Complex Formation with IκB Kinase-α and NIK

Woronicz, J. D., Gao, X., Cao, Z., Rothe, M., & Goeddel, D. V. (1997) · Science · doi:10.1126/science.278.5339.866 · Cited by 1,183 · see citing works

Identification and Characterization of an IκB Kinase

Régnier, C. H., Song, H. Y., Gao, X., Goeddel, D. V., Cao, Z., & Rothe, M. (1997) · Cell · doi:10.1016/s0092-8674(00)80344-x · Cited by 1,176 · see citing works

Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor

Baeuerle, P. A., & Baltimore, D. (1988) · Cell · doi:10.1016/0092-8674(88)90382-0 · Cited by 1,166 · see citing works

Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune responses

Sha, W. C., Liou, H.-C., TUOMANEN, E. I., & Baltimore, D. (1995) · Cell · doi:10.1016/0092-8674(95)90415-8 · Cited by 1,158 · see citing works

NF-κB Controls Expression of Inhibitor IκBα: Evidence for an Inducible Autoregulatory Pathway

Sun, S., Ganchi, P. A., Ballard, D. W., & Greene, W. C. (1993) · Science · doi:10.1126/science.8096091 · Cited by 1,108 · see citing works

The Death Domain Kinase RIP Mediates the TNF-Induced NF-κB Signal

Kelliher, M. A., Grimm, S., Ishida, Y., Kuo, F., Stanger, B. Z., & Leder, P. (1998) · Immunity · doi:10.1016/s1074-7613(00)80535-x · Cited by 1,102 · see citing works

Complementation Cloning of NEMO, a Component of the IκB Kinase Complex Essential for NF-κB Activation

Yamaoka, S., Courtois, G., Chable-Bessia, C., Whiteside, S. T., Weil, R., Agou, F., Kirk, H., Kay, R. J., & Israël, A. (1998) · Cell · doi:10.1016/s0092-8674(00)81466-x · Cited by 1,077 · see citing works

An Essential Role for BAFF in the Normal Development of B Cells Through a BCMA-Independent Pathway

Schiemann, B. J., Gommerman, J. L., Vora, K. A., Cachero, T. G., Shulga‐Morskaya, S., Dobles, M., Frew, E. M., & Scott, M. L. (2001) · Science · doi:10.1126/science.1061964 · Cited by 1,070 · see citing works

Series Introduction: The transcription factor NF-κB and human disease

Baldwin, A. S. (2001) · Journal of Clinical Investigation · doi:10.1172/jci11891 · Cited by 990 · see citing works

Identification of paracaspases and metacaspases: two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma

Uren (2000) · Molecular Cell · Cited by 971 · see citing works

TIRAP: an adapter molecule in the Toll signaling pathway

Horng, T., Barton, G. M., & Medzhitov, R. M. (2001) · Nature Immunology · doi:10.1038/ni0901-835 · Cited by 970 · see citing works

Modulation of Akt kinase activity by binding to Hsp90

Sato, S., Fujita, N., & Tsuruo, T. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.170276797 · Cited by 967 · see citing works

Severe Liver Degeneration in Mice Lacking the IκB Kinase 2 Gene

Li, Q., Antwerp, D. V., Mercurio, F., Lee, K., & Verma, I. M. (1999) · Science · doi:10.1126/science.284.5412.321 · Cited by 963 · see citing works

The Phosphorylation Status of Nuclear NF-ΚB Determines Its Association with CBP/p300 or HDAC-1

Zhong, H., May, M. J., Jimi, E., & Ghosh, S. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00477-x · Cited by 930 · see citing works

The IKKβ Subunit of IκB Kinase (IKK) is Essential for Nuclear Factor κB Activation and Prevention of Apoptosis

Li, Z., Chu, W., Hu, Y., Delhase, M., Deerinck, T. J., Ellisman, M. H., Johnson, R. S., & Karin, M. (1999) · The Journal of Experimental Medicine · doi:10.1084/jem.189.11.1839 · Cited by 927 · see citing works

NF-κB signaling pathways in mammalian and insect innate immunityPreprint

Silverman, N. S., & Maniatis, T. (2001) · Genes & Development · doi:10.1101/gad.909001 · Cited by 904 · see citing works

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

Sun, Z., Arendt, C., Ellmeier, W., Schaeffer, E. M., Sunshine, M. J., Gandhi, L., Annes, J. P., Petrzilka, D., Kupfer, A., Schwartzberg, P. L., et al. (2000) · Nature · doi:10.1038/35006090 · Cited by 894 · see citing works

BAFF-R, a Newly Identified TNF Receptor That Specifically Interacts with BAFF

Thompson, J. S., Bixler, S. A., Qian, F., Vora, K. A., Scott, M. L., Cachero, T. G., Hession, C. A., Schneider, P., Sizing, I., Mullen, C., et al. (2001) · Science · doi:10.1126/science.1061965 · Cited by 890 · see citing works

Positive and Negative Regulation of IκB Kinase Activity Through IKKβ Subunit Phosphorylation

Delhase, M., Hayakawa, M., Chen, Y., & Karin, M. (1999) · Science · doi:10.1126/science.284.5412.309 · Cited by 852 · see citing works

Toll-like receptor-mediated NF-kappaB activation: a phylogenetically conserved paradigm in innate immunity.

Zhang, G.-L., & Ghosh, S. (2001) · Journal of Clinical Investigation · doi:10.1172/jci11837 · Cited by 842 · see citing works

NF-κB-Inducing Kinase Regulates the Processing of NF-κB2 p100

Xiao, G., Harhaj, E. W., & Sun, S. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00187-3 · Cited by 836 · see citing works

The Transcriptional Activity of NF-κB Is Regulated by the IκB-Associated PKAc Subunit through a Cyclic AMP–Independent Mechanism

Zhong, H., Suyang, H., Erdjument‐Bromage, H., Tempst, P., & Ghosh, S. (1997) · Cell · doi:10.1016/s0092-8674(00)80222-6 · Cited by 828 · see citing works

Abnormal Morphogenesis But Intact IKK Activation in Mice Lacking the IKKα Subunit of IκB Kinase

Hu, Y., Baud, V., Delhase, M., Zhang, P., Deerinck, T. J., Ellisman, M. H., Johnson, R. S., & Karin, M. (1999) · Science · doi:10.1126/science.284.5412.316 · Cited by 822 · see citing works

Structure of an IκBα/NF-κB Complex

Jacobs, M. D., & Harrison, S. C. (1998) · Cell · doi:10.1016/s0092-8674(00)81698-0 · Cited by 822 · see citing works

CREB-binding protein/p300 are transcriptional coactivators of p65

Gerritsen, M. E., Williams, A. J., Neish, A. S., Moore, S., Shi, Y., & Collins, T. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.7.2927 · Cited by 811 · see citing works

TNF-α Induction by LPS Is Regulated Posttranscriptionally via a Tpl2/ERK-Dependent Pathway

Dumitru, C. D., Ceci, J. D., Tsatsanis, C., Kontoyiannis, D. L., Stamatakis, K., Lin, J., Patriotis, C., Jenkins, N. A., Copeland, N. G., Kollias, G. A., et al. (2000) · Cell · doi:10.1016/s0092-8674(00)00210-5 · Cited by 801 · see citing works

Akt Stimulates the Transactivation Potential of the RelA/p65 Subunit of NF-κB through Utilization of the IκB Kinase and Activation of the Mitogen-activated Protein Kinase p38

Madrid, L. V., Mayo, M. W., Reuther, J. Y., & Baldwin, A. S. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m101103200 · Cited by 777 · see citing works

The Toll-receptor family and control of innate immunity.

Kopp, E., & Medzhitov, R. (1999) · Current Opinion in Immunology · doi:10.1016/s0952-7915(99)80003-x · Cited by 734 · see citing works

The Lymphotoxin β Receptor Controls Organogenesis and Affinity Maturation in Peripheral Lymphoid Tissues

Fütterer, A., Mink, K., Luz, A., Kosco‐Vilbois, M. H., & Pfeffer, K. (1998) · Immunity · doi:10.1016/s1074-7613(00)80588-9 · Cited by 732 · see citing works

The p65 (RelA) Subunit of NF-κB Interacts with the Histone Deacetylase (HDAC) Corepressors HDAC1 and HDAC2 To Negatively Regulate Gene Expression

Ashburner, B. P., Westerheide, S. D., & Baldwin, A. S. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.20.7065-7077.2001 · Cited by 732 · see citing works

Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression.Preprint

Köntgen, F., Grumont, R. J., Strasser, A., Metcalf, D., Li, R., Tarlinton, D. M., & Gerondakis, S. (1995) · Genes & Development · doi:10.1101/gad.9.16.1965 · Cited by 727 · see citing works

Evidence for a Role of CRM1 in Signal-Mediated Nuclear Protein Export

Ossareh‐Nazari, B., Bachelerie, F., & Dargemont, C. (1997) · Science · doi:10.1126/science.278.5335.141 · Cited by 723 · see citing works

Glucocorticoid Receptor Recruitment of Histone Deacetylase 2 Inhibits Interleukin-1β-Induced Histone H4 Acetylation on Lysines 8 and 12

Ito, K., Barnes, P. J., & Adcock, I. M. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.18.6891-6903.2000 · Cited by 723 · see citing works

Regulation of NF-κB by Cyclin-Dependent Kinases Associated with the p300 Coactivator

Perkins, N. D., Felzien, L. K., Betts, J. C., Leung, K., Beach, D., & Nabel, G. J. (1997) · Science · doi:10.1126/science.275.5299.523 · Cited by 722 · see citing works

Selective Inhibition of NF-κB Activation by a Peptide That Blocks the Interaction of NEMO with the IκB Kinase Complex

May, M. J., D’Acquisto, F., Madge, L. A., Glöckner, J., Pober, J. S., & Ghosh, S. (2000) · Science · doi:10.1126/science.289.5484.1550 · Cited by 678 · see citing works

Akt Suppresses Apoptosis by Stimulating the Transactivation Potential of the RelA/p65 Subunit of NF-κB

Madrid, L. V., Wang, C.-Y., D, D. C. G., Schottelius, A. J. G., Baldwin, A. S., & Mayo, M. W. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.5.1626-1638.2000 · Cited by 634 · see citing works

An exceptionally well-preserved theropod dinosaur from the Yixian Formation of China

Chen, P., Dong, Z.-M., & Zhen, S. (1998) · Nature · doi:10.1038/34356 · Cited by 623 · see citing works

Mutual regulation of the transcriptional activator NF-kappa B and its inhibitor, I kappa B-alpha.

Brown, K., Park, S., KANNO, T., Franzoso, G., & Siebenlist, U. K. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.6.2532 · Cited by 621 · see citing works

Crystal structure of p50/p65 heterodimer of transcription factor NF-κB bound to DNA

Chen, F. E., Huang, D.-B., Chen, Y., & Ghosh, G. (1998) · Nature · doi:10.1038/34956 · Cited by 612 · see citing works

Limb and Skin Abnormalities in Mice Lacking IKKα

Takeda, K., Takeuchi, O., Tsujimura, T., Itami, S., Adachi, O., Kawai, T., Sanjo, H., Yoshikawa, K., Terada, N., & Akira, S. (1999) · Science · doi:10.1126/science.284.5412.313 · Cited by 609 · see citing works

The Crystal Structure of the IκBα/NF-κB Complex Reveals Mechanisms of NF-κB Inactivation

Huxford, T., Huang, D.-B., Malek, S., & Ghosh, G. (1998) · Cell · doi:10.1016/s0092-8674(00)81699-2 · Cited by 581 · see citing works

Structure of NF-κB p50 homodimer bound to a κB site

Ghosh, G., Duyne, G. D. V., Ghosh, S., & Sigler, P. B. (1995) · Nature · doi:10.1038/373303a0 · Cited by 570 · see citing works

Embryonic Lethality, Liver Degeneration, and Impaired NF-κB Activation in IKK-β-Deficient Mice

Tanaka, M., Fuentes, M. E., Yamaguchi, T., Durnin, M., Dalrymple, S. A., Hardy, K. L., & Goeddel, D. V. (1999) · Immunity · doi:10.1016/s1074-7613(00)80042-4 · Cited by 569 · see citing works

The NF-κB Activation Pathway: A Paradigm in Information Transfer from Membrane to Nucleus

Rothwarf, D., & Karin, M. (1999) · Science's STKE · doi:10.1126/stke.1999.5.re1 · Cited by 553 · see citing works

Lymphotoxin α/β and Tumor Necrosis Factor Are Required for Stromal Cell Expression of Homing Chemokines in B and T Cell Areas of the Spleen

Ngo, V. N., Körner, H., Gunn, M. D., Schmidt, K. N., Riminton, S., Cooper, M. D., Browning, J. L., Sedgwick, J. D., & Cyster, J. G. (1999) · The Journal of Experimental Medicine · doi:10.1084/jem.189.2.403 · Cited by 552 · see citing works

Bcl10 Is a Positive Regulator of Antigen Receptor–Induced Activation of NF-κ B and Neural Tube Closure

Ruland, J., Duncan, G. S., Elia, A., Barrantes, I. D. B., Nguyen, L. T., Plyte, S., Millar, D. G., Bouchard, D., Wakeham, A. C., Ohashi, P. S., et al. (2001) · Cell · doi:10.1016/s0092-8674(01)00189-1 · Cited by 545 · see citing works

Structure of the NF-κB p50 homodimer bound to DNA

Müller, C. W., Rey, F. A., Sodeoka, M., Verdine, G. L., & Harrison, S. C. (1995) · Nature · doi:10.1038/373311a0 · Cited by 536 · see citing works

Transcriptional Regulation of the Intercellular Adhesion Molecule-1 Gene by Inflammatory Cytokines in Human Endothelial Cells

Ledebur, H. C., & Parks, T. P. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.2.933 · Cited by 536 · see citing works

NF-κB-inducing kinase activates IKK-α by phosphorylation of Ser-176

Lei, L., Cao, Z., & Goeddel, D. V. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.7.3792 · Cited by 536 · see citing works

Severe liver degeneration and lack of NF-kappaB activation in NEMO/IKKgamma-deficient mice.

Rudolph, D., Yeh, W., Wakeham, A. C., Rudolph, B., Nallainathan, D., Potter, J., Elia, A., & Mak, T. W. (2000) · PubMed Central · Cited by 518 · see citing works

IKKα Provides an Essential Link between RANK Signaling and Cyclin D1 Expression during Mammary Gland Development

Cao, Y., Bonizzi, G., Seagroves, T. N., Greten, F. R., Johnson, R. S., Schmidt, E. V., & Karin, M. (2001) · Cell · doi:10.1016/s0092-8674(01)00599-2 · Cited by 479 · see citing works

Severe liver degeneration and lack of <i>NF</i>-κ<i>B</i> activation in <i>NEMO/IKKγ</i>-deficient mice

Rudolph, D., Yeh, W.-C., Wakeham, A., Rudolph, B., Nallainathan, D., Potter, J., Elia, A. J., & Mak, T. W. (2000) · Genes &amp; Development · doi:10.1101/gad.14.7.854 · Cited by 479 · see citing works

IKK1-deficient mice exhibit abnormal development of skin and skeletonPreprint

Li, Q., Lu, Q., Hwang, J. Y., Büscher, D., Lee, K., Izpisúa‐Belmonte, J. C., & Verma, I. M. (1999) · Genes & Development · doi:10.1101/gad.13.10.1322 · Cited by 470 · see citing works

Recruitment of the IKK Signalosome to the p55 TNF Receptor

Zhang, S. Q., Kovalenko, A., Cantarella, G., & Wallach, D. (2000) · Immunity · doi:10.1016/s1074-7613(00)80183-1 · Cited by 456 · see citing works

Tumor Necrosis Factor α-induced Phosphorylation of RelA/p65 on Ser529 Is Controlled by Casein Kinase II

Wang, D., Westerheide, S. D., Ostrander, J. H., & Baldwin, A. S. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m001358200 · Cited by 454 · see citing works

Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-κb-inducing kinase

Shinkura, R., Kitada, K., Matsuda, F., Tashiro, K., Ikuta, K., Suzuki, M., Kogishi, K., Serikawa, T., & Honjo, T. (1999) · Nature Genetics · doi:10.1038/8780 · Cited by 451 · see citing works

Direct Phosphorylation of IκB by IKKα and IKKβ: Discrimination Between Free and NF-κB-Bound Substrate

Zandi, E., Chen, Y., & Karin, M. (1998) · Science · doi:10.1126/science.281.5381.1360 · Cited by 446 · see citing works

NEMO/IKKγ-Deficient Mice Model Incontinentia Pigmenti

Schmidt‐Supprian, M., Bloch, W., Courtois, G., Addicks, K., Israël, A., Rajewsky, K., & Pasparakis, M. (2000) · Molecular Cell · doi:10.1016/s1097-2765(00)80263-4 · Cited by 437 · see citing works

Recruitment of CBP/p300 by the IFNβ Enhanceosome Is Required for Synergistic Activation of Transcription

Merika, M., Williams, A. J., Chen, G., Collins, T., & Thanos, D. (1998) · Molecular Cell · doi:10.1016/s1097-2765(00)80028-3 · Cited by 435 · see citing works

Autoregulation of I kappa B alpha activity.

Chiao, P. J., Miyamoto, S., & Verma, I. M. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.1.28 · Cited by 434 · see citing works

The Distinct Roles of TRAF2 and RIP in IKK Activation by TNF-R1

Devin, A., Cook, A., Lin, Y., Rodriguez, Y., Kelliher, M. A., & Liu, Z.-G. (2000) · Immunity · doi:10.1016/s1074-7613(00)80194-6 · Cited by 433 · see citing works

Inducible Nuclear Expression of Newly Synthesized IκBα Negatively Regulates DNA-Binding and Transcriptional Activities of NF-κB

Arenzana‐Seisdedos, F., Thompson, J., Rodríguez, M. S., Bachelerie, F., Thomas, D., & Hay, R. T. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.5.2689 · Cited by 433 · see citing works

Transcriptional Activation by NF-κB Requires Multiple Coactivators

Sheppard, K.-A., Rose, D. W., Haque, Z. K., Kurokawa, R., McInerney, E. M., Westin, S. K., Thanos, D., Rosenfeld, M. G., Glass, C. K., & Collins, T. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.9.6367 · Cited by 430 · see citing works

Mice Deficient in Nuclear Factor (NF)-κB/p52 Present with Defects in Humoral Responses, Germinal Center Reactions, and Splenic Microarchitecture

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Bcl10 and MALT1, Independent Targets of Chromosomal Translocation in MALT Lymphoma, Cooperate in a Novel NF-κB Signaling Pathway

Lucas, P. C., Yonezumi, M., Inohara, N., McAllister‐Lucas, L. M., Abazeed, M. E., Chen, F. F., Yamaoka, S., Seto, M., & Núñez, G. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m009984200 · Cited by 417 · see citing works

Defective Lymphotoxin-β Receptor-Induced NF-κB Transcriptional Activity in NIK-Deficient Mice

Li, Y., Wu, L., Wesche, H., Arthur, C. D., White, J. M., Goeddel, D. V., & Schreiber, R. D. (2001) · Science · doi:10.1126/science.1058453 · Cited by 408 · see citing works

Regulatory functions of ubiquitination in the immune system

Ben‐Neriah, Y. (2002) · Nature Immunology · doi:10.1038/ni0102-20 · Cited by 403 · see citing works

TNF-Induced Recruitment and Activation of the IKK Complex Require Cdc37 and Hsp90

Chen, G., Cao, P., & Goeddel, D. V. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00450-1 · Cited by 399 · see citing works

Nuclear localization of IκBα promotes active transport of NF-κB from the nucleus to the cytoplasm

Arenzana‐Seisdedos, F., Turpin, P., Rodríguez, M. S., Thomas, D., Hay, R. T., Virelizier, J., & Dargemont, C. (1997) · Journal of Cell Science · doi:10.1242/jcs.110.3.369 · Cited by 399 · see citing works

The essential role of MEKK3 in TNF-induced NF-κB activation

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