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Percutaneous Pulmonary Valve Implantation: Impact of Evolving Technology and Learning Curve on Clinical Outcome
Open accessAbstract
Background— Percutaneous pulmonary valve implantation was introduced in the year 2000 as a nonsurgical treatment for patients with right ventricular outflow tract dysfunction. Methods and Results— Between September 2000 and February 2007, 155 patients with stenosis and/or regurgitation underwent percutaneous pulmonary valve implantation. This led to significant reduction in right ventricular systolic pressure (from 63±18 to 45±13 mm Hg, P <0.001) and right ventricular outflow tract gradient (from 37±20 to 17±10 mm Hg, P <0.001). Follow-up ranged from 0 to 83.7 months (median 28.4 months). Freedom from reoperation was 93% (±2%), 86% (±3%), 84% (±4%), and 70% (±13%) at 10, 30, 50, and 70 months, respectively. Freedom from transcatheter reintervention was 95% (±2%), 87% (±3%), 73% (±6%), and 73% (±6%) at 10, 30, 50, and 70 months, respectively. Survival at 83 months was 96.9%. On time-dependent analysis, the first series of 50 patients (log-rank test P <0.001) and patients with a residual gradient >25 mm Hg (log-rank test P =0.01) were associated with a higher risk of reoperations. Conclusions— Percutaneous pulmonary valve implantation resulted in the ability to avoid surgical right ventricular outflow tract revision in the majority of cases. This procedure might reduce the number of operations needed over the total lifetime of patients with right ventricle–to–pulmonary artery conduits.
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Percutaneous Pulmonary Valve Implantation in Humans: Results in 59 Consecutive Patients
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ESC Guidelines for the management of grown-up congenital heart disease (new version 2010)
Endorsed by the Association for European Paediatric Cardiology (AEPC), Authors/Task Force Members, Baumgartner, H., Bonhoeffer, P., De Groot, N. M. S., de Haan, F., Deanfield, J. E., Galie, N., Gatzoulis, M. A., Gohlke-Baerwolf, C., et al. (2010) · European Heart Journal · doi:10.1093/eurheartj/ehq249 · Cited by 2,331
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Bailliard, F., & Anderson, R. H. (2009) · Orphanet Journal of Rare Diseases · doi:10.1186/1750-1172-4-2 · Cited by 345
Valente, A. M., Cook, S., Festa, P., Ko, H. H., Krishnamurthy, R., Taylor, A. M., Warnes, C. A., Kreutzer, J., & Geva, T. (2014) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2013.11.009 · Cited by 317
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Metadata
- Authors
- Lurz, P., Coats, L., Khambadkone, S., Nordmeyer, J., Boudjemline, Y., Schievano, S., Muthurangu, V., Lee, T. Y., Parenzan, G., Derrick, G., Cullen, S., Walker, F., Tsang, V., Deanfield, J., Taylor, A. M., & Bonhoeffer, P.
- Venue
- Circulation
- Published
- 2008-04-15
- Volume
- 117
- Issue
- 15
- Pages
- 1964-1972
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2011009799
- Cited by
- 481
- References
- 20
- FWCI
- 29.78
- Type
- journal article
- Language
- en
- Open access
- green
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- Lurz, P., Coats, L., Khambadkone, S., Nordmeyer, J., Boudjemline, Y., Schievano, S., Muthurangu, V., Lee, T. Y., Parenzan, G., Derrick, G., Cullen, S., Walker, F., Tsang, V., Deanfield, J., Taylor, A. M., & Bonhoeffer, P. (2008). Percutaneous Pulmonary Valve Implantation: Impact of Evolving Technology and Learning Curve on Clinical Outcome. Circulation. https://doi.org/10.1161/circulationaha.107.735779
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