Nicotinamide Riboside Preserves Cardiac Function in a Mouse Model of Dilated Cardiomyopathy

Diguet, Nicolas, Trammell, Samuel A.J., Tannous, Cynthia, Deloux, Robin, Piquereau, Jérôme, Mougenot, Nathalie, Gouge, Anne, Gressette, Mélanie +11 more·2018·Circulation

DOI 10.1161/circulationaha.116.026099

Cited by (370)

Items 101–200 of 370

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Baeki E. Kang, Jun‐Yong Choi, Sokrates Stein, Dongryeol Ryu · 2020 · European Journal of Clinical Investigation
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NAD+ and Vascular Dysfunction: From Mechanisms to Therapeutic Opportunities
Mahmoud Abdellatif, Heiko Bugger, Guido Kroemer, Simon Sedej · 2022 · Journal of Lipid and Atherosclerosis
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Marie Breton, Jean-François Costemale-Lacoste, Zhenlin Li, Carmelo Lafuente‐Lafuente, Joël Belmin, Mathias Mericskay · 2020 · Experimental Gerontology
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Faisal Hayat, Manoj Sonavane, Mikhail V. Makarov, Samuel A.J. Trammell, Pamela McPherson, Natalie R. Gassman, Marie E. Migaud · 2021 · International Journal of Molecular Sciences
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Hyoung Kyu Kim, Min Gyu Kim, Jubert C. Marquez, Seung Hun Jeong, Tae Hee Ko, Yeon Hee Noh, Pham Trong Kha, Ha Min Choi, Dong‐Hyun Kim, Jong‐Tae Kim et al. · 2022 · JACC Basic to Translational Science
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Robin Deloux, Cynthia Tannous, Arnaud Ferry, Zhenlin Li, Mathias Mericskay · 2018 · Frontiers in Physiology
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Khanh V. Doan, Timothy S. Luongo, Thato T Ts'olo, Won Dong Lee, David W. Frederick, Sarmistha Mukherjee, Gabriel Komla Adzika, Caroline E Perry, Ryan B. Gaspar, Nicole M. Walker et al. · 2024 · Nature Cardiovascular Research
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Nicotinamide riboside has minimal impact on energy metabolism in mouse models of mild obesity
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Tachycardiomyopathy entails a dysfunctional pattern of interrelated mitochondrial functions
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Duo Feng, Dongzhu Xu, Nobuyuki Murakoshi, Kazuko Tajiri, Rujie Qin, Saori Yonebayashi, Yuta Okabe, Siqi Li, Zixun Yuan, Kazutaka Aonuma et al. · 2020 · International Journal of Molecular Sciences
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Zhang, Xiao, Tian, Bing, Deng, Qin, Cao, Jian, Ding, Xionghui, Liu, Qingshuang, Zhang, Yunfei, Ye, Cuilian, Deng, Chun, Qiu, Lin et al. · 2022 · Free Radical Biology and Medicine
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Giorgia Del Favero, Alois Bonifacio, Teisha J. Rowland, Shanshan Gao, Kunhua Song, Valter Sergo, ERIC D. ADLER, Luisa Mestroni, Orfeo Sbaizero, Matthew R.G. Taylor · 2020 · Journal of Clinical Medicine
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Bacterial PncA improves diet-induced NAFLD in mice by enabling the transition from nicotinamide to nicotinic acid
Feng, Shengyu, Guo, Liuling, Wang, Hao, Yang, Shanshan, Liu, Hailiang · 2023 · Communications Biology
NAD + -A Hub of Energy Metabolism in Heart Failure
Yaoxin Wu, Zuowei Pei, Peng Qu · 2023 · International Journal of Medical Sciences
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Abdalla Ahmed, Jibran Syed, Lijun Chi, Yaxu Wang, Carmina Angelica Perez-Romero, Dorothy Lee, Etri Kocaqi, Amalia Caballero, Jielin Yang, Quetzalcóatl Escalante‐Covarrubias et al. · 2023 · Nature Cardiovascular Research
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Janne Purhonen, Jayasimman Rajendran, Saara Tegelberg, Olli‐Pekka Smolander, Eija Pirinen, Jukka Kallijärvi, Vineta Fellman · 2018 · The FASEB Journal
Scalable syntheses of traceable ribosylated NAD + precursors
Mikhail V. Makarov, Nekoda W. Harris, Mara da Silva Rodrigues, Marie E. Migaud · 2019 · Organic & Biomolecular Chemistry
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Matthew George, Qiming Duan, Abigail Nagle, Irfan S. Kathiriya, Yu Huang, Kavitha S. Rao, Saptarsi M. Haldar, Benoit G. Bruneau · 2019 · Development
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Yang Yuan, Bing Liang, Xinlin Liu, Wenjing Liu, Binghuan Huang, Shanbo Yang, Yuan-Zhen Gao, Jingsen Meng, Mengjiao Li, Ting Ye et al. · 2022 · Cell Death Discovery
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Minkeun Song, Saro H. Armenian, Rusha Bhandari, Kyuwan Lee, Kirsten K. Ness, Mary Putt, Lanie Lindenfeld, Saro B. Manoukian, Kristin Wade, Anna Dedio et al. · 2022 · BMC Cancer
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Won-Suk Song, Xiyu Shen, Kang Du, Cuauhtemoc B. Ramirez, Sang Hee Park, Yang Cao, Johnny Le, Hosung Bae, Joo‐Hwan Kim, Yujin Chun et al. · 2025 · Cell Metabolism
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SIRT1-dependent restoration of NAD+ homeostasis after increased extracellular NAD+ exposure
Daniela Buonvicino, Giuseppe Ranieri, Maria Gloria Pittelli, Andrea Lapucci, Stefania Bragliola, Alberto Chiarugi · 2021 · Journal of Biological Chemistry
Efficient Assay and Marker Significance of NAD+ in Human Blood
Natalia V. Balashova, Lev G. Zavileyskiy, Artem V. Artiukhov, Leonid A. Shaposhnikov, Sidorova Op, Vladimir I. Tishkov, Angela Tramonti, ANASTASIA A. POMETUN, Victoria I. Bunik · 2022 · Frontiers in Medicine
Emerging interactions between mitochondria and NAD+ metabolism in cardiometabolic diseases
Azadeh Nasuhidehnavi, Weronika Zarzycka, Ignacy Gorecki, Ying Ann Chiao, Chi Fung Lee · 2024 · Trends in Endocrinology and Metabolism
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Johannes Burtscher, Vanna Denti, Johanna Maria Gostner, Alexander KH Weiss, Barbara Strasser, Katharina Hüfner, Martin Burtscher, Giuseppe Paglia, Martin Kopp, Tobias Dünnwald · 2024 · Ageing Research Reviews
Therapeutic Significance of microRNA-Mediated Regulation of PARP-1 in SARS-CoV-2 Infection
Sabyasachi Dash, Chandravanu Dash, Jui Pandhare · 2021 · Non-Coding RNA
NMR-Based Metabolomic Analysis of Sera in Mouse Models of CVB3-Induced Viral Myocarditis and Dilated Cardiomyopathy
Qing Kong, Jinping Gu, Ruohan Lu, Caihua Huang, Xiaomin Hu, Weifeng Wu, Donghai Lin · 2022 · Biomolecules
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Takaso, Yuji, Noda, Masao, Hattori, Tsuyoshi, Roboon, Jureepon, Hatano, Miyako, Sugimoto, Hisashi, Brenner, Charles, Yamamoto, Yasuhiko, Okamoto, Hiroshi, Higashida, Haruhiro et al. · 2020 · Scientific Reports
Mechano-energetic uncoupling in hypertrophic cardiomyopathy: Pathophysiological mechanisms and therapeutic opportunities
Vasco Sequeira, Mark T. Waddingham, Hirotsugu Tsuchimochi, Christoph Maack, James T. Pearson · 2023 · Journal of Molecular and Cellular Cardiology Plus
Atrial fibrillation
Bianca J.J.M. Brundel, Ai, Xun, Hills, Mellanie True, Myrthe F. Kuipers, Gregory Y.H. Lip, Natasja M. S. de Groot · 2016 · Nature Reviews Disease Primers
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Marine De Loof, Edith Renguet, Audrey Ginion, Caroline Bouzin, Sandrine Horman, Christophe Beauloye, Luc Bertrand, Laurent Bultot · 2023 · American Journal of Physiology-Heart and Circulatory Physiology
Mitochondrial NAD + -mediated mitophagy alleviates type I interferon response to the cytosolic mitochondrial DNA
Tian Lan, Dantong Shang, Lan Lin, Haoyu Wang, Juan Zou, Mengxin Hu, Hanhua Cheng, Rongjia Zhou · 2025 · Autophagy
Nicotinamide riboside kinases regulate skeletal muscle fiber-type specification and are rate-limiting for metabolic adaptations during regeneration
Tanja Sonntag, Sara Ancel, Sonia Karaz, Paulina Cichosz, Guillaume E. Jacot, Maria Pilar Giner, José Luis Sanchez-Garcia, Alice Pannérec, Sofia Moco, Vincenzo Sorrentino et al. · 2022 · Frontiers in Cell and Developmental Biology
Deficiency of nuclear receptor interaction protein leads to cardiomyopathy by disrupting sarcomere structure and mitochondrial respiration
Kai‐Chien Yang, Kai‐Wen Chuang, Won-Shin Yen, Ssu-Yu Lin, Hsin‐Hsiung Chen, Szu‐Wei Chang, Yu-Shan Lin, Wan‐Lin Wu, Yeou‐Ping Tsao, Wen‐Pin Chen et al. · 2019 · Journal of Molecular and Cellular Cardiology
Targeting mitochondria in hypertrophic cardiomyopathy
Vasco Sequeira, Angelika Batzner, Christoph Maack · 2023 · European Heart Journal
Research progress of AMP-activated protein kinase and cardiac aging
Zhengqi Qiu, Yufei Li, Yancheng Fu, Yanru Yang · 2023 · Open Life Sciences
Alterations in tryptophan metabolism and de novo NAD+ biosynthesis within the microbiota-gut-brain axis in chronic intestinal inflammation
Jeannie Devereaux, Ainsley M. Robinson, Rhian G Stavely, Majid Davidson, Narges Dargahi, Ramya Ephraim, Dimitros Kiatos, Vasso Apostolopoulos, Kulmira Nurgali · 2024 · Frontiers in Medicine
Myocardial infarction and oxidative damage in animal models: objective and expectations from the application of cysteine derivatives
Marija Angelovski, Nikola Hadzi‐Petrushev, Vadim M. Mitrokhin, Andre G. Kamkin, Mitko I. Mladenov · 2022 · Toxicology Mechanisms and Methods
Nicotinamide Riboside for the Prevention and Treatment of Doxorubicin Cardiomyopathy. Opportunities and Prospects
Ekaterina Podyacheva, Yana G. Toropova · 2021 · Nutrients
Heart failure in the elderly: epidemiology, mechanisms, and management
Rudolf A. de Boer, Mahmoud Abdellatif, Johann K Bauersachs, Veronique Lee Roger · 2026 · European Heart Journal
Sirtuin1 in vascular endothelial function, an overview
Jitendra Kumar, Santosh Kumar · 2021 · Epigenetics
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Ana Carolina Mieko Omoto, Jussara Marcia do Carmo, Benjamin J. Nelson, Nikaela M. Aitken, Xuemei Dai, Sydney P. Moak, Elizabeth Flynn, Zhen Wang, Alan J. Mouton, Xuan Li et al. · 2022 · Journal of the American Heart Association
Xinyang tablet alleviated cardiac dysfunction in a cardiac pressure overload model by regulating the receptor-interacting serum/three-protein kinase 3/FUN14 domain containing 1-mediated mitochondrial unfolded protein response and mitophagy
Xin Dong, Hao-wen Zhuang, Ruijia Wen, Yu‐Sheng Huang, Bingxue Liang, Huan Li, Shaoxiang Xian, Chun Li, Junyan Wang, Junyan Wang · 2024 · Journal of Ethnopharmacology
Nicotinamide Riboside Supplementation Benefits in Patients With Werner Syndrome: A Double‐Blind Randomized Crossover Placebo‐Controlled Trial
Mayumi Shoji, Hisaya Kato, Masaya Koshizaka, Hiyori Kaneko, Yusuke Baba, Takahiro Ishikawa, Naoya Teramoto, Daisuke Kinoshita, Ayano Yamaguchi, Yukari Maeda et al. · 2025 · Aging Cell
Nicotinamide improves NAD + levels to protect against acetaminophen-induced acute liver injury in mice
J Xu, L Zhang, R. Jiang, Kai Hu, D Hu, C Liao, Shao‐Liang Jiang, Yongqiang Yang, Jiayi Huang, Li Ping Tang et al. · 2021 · Human & Experimental Toxicology
Co-Polarized [1-13C]Pyruvate and [1,3-13C2]Acetoacetate Provide a Simultaneous View of Cytosolic and Mitochondrial Redox in a Single Experiment
Gaurav Sharma, Xiaodong Wen, Nesmine R. Maptue, Thomas Hever, Craig R. Malloy, A. Dean Sherry, Chalermchai Khemtong · 2021 · ACS Sensors
Impact of circadian time of dosing on cardiomyocyte-autonomous effects of glucocorticoids
Michelle Wintzinger, Manoj Panta, Karen Miz, Ashok Daniel Prabakaran, Hima Bindu Durumutla, Michelle A. Sargent, Clara Bien Peek, Joseph T. Bass, Jeffery D. Molkentin, Mattia Quattrocelli · 2022 · Molecular Metabolism
The use of Nicotinamide and Nicotinamide riboside as an adjunct therapy in the treatment of glaucoma
Samuel Goulart Nacácio e Silva, Marcelo Luís Occhiutto, Vital Paulino Costa · 2023 · European Journal of Ophthalmology
Cardioprotective effects of α‐cardiac actin on oxidative stress in a dilated cardiomyopathy mouse model
Aude Angelini, Mark-Alexander Gorey, Florent Dumont, Nathalie Mougenot, Maria Chatzifrangkeskou, Antoine Muchir, Zhenlin Li, Mathias Mericskay, Jean‐François Decaux · 2019 · The FASEB Journal
Nicotinamide Riboside Improves Cardiac Function and Prolongs Survival After Disruption of the Cardiomyocyte Clock
Pieterjan Dierickx, Bryce J. Carpenter, Isaac J. Celwyn, Daniel P. Kelly, Joseph A. Baur, Mitchell A. Lazar · 2022 · Frontiers in Molecular Medicine
BNC1 deficiency induces mitochondrial dysfunction-triggered spermatogonia apoptosis through the CREB/SIRT1/FOXO3 pathway: the therapeutic potential of nicotinamide riboside and metformin
Fei-Da Ni, Feixia Wang, Jingyi Li, Yifeng Liu, Xiao Sun, Jianpeng Chen, Jiaqun Li, Yanye Zhang, Jiani Jin, Xiaohang Ye et al. · 2023 · Biology of Reproduction
Global gene expression profiling of perirenal brown adipose tissue whitening in goat kids reveals novel genes linked to adipose remodeling
Le Zhao, Haili Yang, Minhao Li, Xiao Min, Xingchun Li, Lei Cheng, Wenqiang Cheng, Meixi Chen, Yongju Zhao · 2024 · Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology
Mitochondrial cardiomyopathies: pathogenesis, diagnosis, and treatment
Christoph Maack, Jan Dudek, Edoardo Bertero, Emmanouil Tampakakis, Hilary J. Vernon · 2025 · European Heart Journal
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