The DOI matches its Crossref record; 114 of the 114 references it cites were found in a registry or an index.
Research Priorities for Heart Failure With Preserved Ejection Fraction: National Heart, Lung, and Blood Institute Working Group Summary
Open accessAbstract
Heart failure with preserved ejection fraction (HFpEF), a major public health problem that is rising in prevalence, is associated with high morbidity and mortality and is considered to be the greatest unmet need in cardiovascular medicine today because of a general lack of effective treatments. To address this challenging syndrome, the National Heart, Lung, and Blood Institute convened a working group made up of experts in HFpEF and novel research methodologies to discuss research gaps and to prioritize research directions over the next decade. Here, we summarize the discussion of the working group, followed by key recommendations for future research priorities. There was uniform recognition that HFpEF is a highly integrated, multiorgan, systemic disorder requiring a multipronged investigative approach in both humans and animal models to improve understanding of mechanisms and treatment of HFpEF. It was recognized that advances in the understanding of basic mechanisms and the roles of inflammation, macrovascular and microvascular dysfunction, fibrosis, and tissue remodeling are needed and ideally would be obtained from (1) improved animal models, including large animal models, which incorporate the effects of aging and associated comorbid conditions; (2) repositories of deeply phenotyped physiological data and human tissue, made accessible to researchers to enhance collaboration and research advances; and (3) novel research methods that take advantage of computational advances and multiscale modeling for the analysis of complex, high-density data across multiple domains. The working group emphasized the need for interactions among basic, translational, clinical, and epidemiological scientists and across organ systems and cell types, leveraging different areas or research focus, and between research centers. A network of collaborative centers to accelerate basic, translational, and clinical research of pathobiological mechanisms and treatment strategies in HFpEF was discussed as an example of a strategy to advance research progress. This resource would facilitate comprehensive, deep phenotyping of a multicenter HFpEF patient cohort with standardized protocols and a robust biorepository. The research priorities outlined in this document are meant to stimulate scientific advances in HFpEF by providing a road map for future collaborative investigations among a diverse group of scientists across multiple domains.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Obesity and diabetes create a pro-inflammatory state and promote endothelial and coronary microvascular dysfunction. 1,7,8”
From Semaglutide versus placebo in people with obesity-related heart failure with preserved ejection fraction: a pooled analysis of the STEP-HFpEF and STEP-HFpEF DM randomised trials (2024) · cites this paper as [1]
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“Obesity is a major risk factor for heart failure (HF) with preserved ejection fraction (HFpEF). 1,2”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
A Novel Paradigm for Heart Failure With Preserved Ejection Fraction
Paulus, W. J., & Tschöpe, C. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.02.092 · Cited by 3,564
Deo, R. C. (2015) · Circulation · doi:10.1161/circulationaha.115.001593 · Cited by 3,466
Antlanger, M., Aschauer, S., Kopecky, C., Hecking, M., Kovarik, J. J., Werzowa, J. M., Mascherbauer, J., Genser, B., Säemann, M. D., & Bonderman, D. (2017) · Kidney & Blood Pressure Research · doi:10.1159/000473868 · Cited by 2,808
Angiotensin–Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction
Solomon, S. D., McMurray, J. J. V., Anand, I. S., Ge, J., Lam, C. S. P., Maggioni, A. P., Martinez, F., Packer, M., Pfeffer, M. A., Pieske, B., et al. (2019) · New England Journal of Medicine · doi:10.1056/nejmoa1908655 · Cited by 2,430
Self-citationPieske, B. M., Tschöpe, C., de Boer, R. A., Fraser, A. G., Anker, S. D., Donal, E., Edelmann, F., Fu, M. L. X., Guazzi, M., Lam, C. S. P., et al. (2019) · European Heart Journal · doi:10.1093/eurheartj/ehz641 · Cited by 1,961
Reddy, Y. N. V., Carter, R. E., Obokata, M., Redfield, M. M., & Borlaug, B. A. (2018) · Circulation · doi:10.1161/circulationaha.118.034646 · Cited by 1,294
Obokata, M., Reddy, Y. N. V., Pislaru, S. V., Melenovsky, V., & Borlaug, B. A. (2017) · Circulation · doi:10.1161/circulationaha.116.026807 · Cited by 1,179
Wild-type transthyretin amyloidosis as a cause of heart failure with preserved ejection fraction
González-López, E., Gallego‐Delgado, M., Guzzo-Merello, G., Moral, F. J. D. H.-D., Marcos, M. C., Robles, C., Bornstein, B., Salas, C., Lara‐Pezzi, E., Alonso‐Pulpón, L., et al. (2015) · European Heart Journal · doi:10.1093/eurheartj/ehv338 · Cited by 1,176
Redfield, M. M., Chen, H. H., Borlaug, B. A., Semigran, M. J., Lee, K. L., Lewis, G. D., LeWinter, M. M., Rouleau, J. L., Bull, D. A., Mann, D. L., et al. (2013) · JAMA · doi:10.1001/jama.2013.2024 · Cited by 1,164
Phenomapping for Novel Classification of Heart Failure With Preserved Ejection Fraction
Shah, S. J., Katz, D. H., Selvaraj, S., Burke, M. A., Yancy, C. W., Gheorghiade, M., Bonow, R. O., Huang, C.-C., & Deo, R. C. (2015) · Circulation · doi:10.1161/circulationaha.114.010637 · Cited by 1,157
Flagged first, then by citations
Cited by
Sorted by citations
Items 201–300 of 436
Palazzuoli, A., Buono, M. G. D., Ruocco, G. M., Caravita, S., Abbate, A., & Lavie, C. J. (2022) · Current Problems in Cardiology · doi:10.1016/j.cpcardiol.2022.101433 · Cited by 9
Lin, M., Qin, Y., Ding, X., Zhang, M., Zhu, W., Wang, J., Leng, C., Lu, X., & Cai, Q. (2022) · The International Journal of Cardiovascular Imaging · doi:10.1007/s10554-022-02731-8 · Cited by 9
Fisher, S. M., Murally, A. R., Rajabally, Z., Almas, T., Azhar, M., Cheema, F. H., Malone, A. J., Hasan, B. S., Aslam, N., Saidi, J., et al. (2023) · Heart Failure Reviews · doi:10.1007/s10741-023-10371-w · Cited by 9
Pandey, A., Gilbert, O. N., & Kitzman, D. W. (2021) · Journal of the American Geriatrics Society · doi:10.1111/jgs.17306 · Cited by 9
Shah, R. V., Hwang, S., Murthy, V. L., Zhao, S., Tanrıverdi, K., Gajjar, P., Duarte, K., Schoenike, M., Farrell, R., Brooks, L. C., et al. (2023) · Journal of the American Heart Association · doi:10.1161/jaha.122.029980 · Cited by 11
Meyer, M., Núñez, J. E., Goyal, P., Silverman, D. N., van Berlo, J. H., & Maharaj, V. (2024) · The Journal of Cardiovascular Aging · doi:10.20517/jca.2024.22 · Cited by 8
Tang, X., Alloosh, M., Ou, Q., Luo, L., Agrawal, D. K., Kalra, D. K., Sturek, M. S., & Bolli, R. (2025) · Basic Research in Cardiology · doi:10.1007/s00395-025-01112-1 · Cited by 8
Hegyi, B., Bailey, L. R. J., Hernández, J. M., Ko, C. Y., Shen, E. Y., Bossuyt, J., Davis, J., & Bers, D. M. (2025) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00227.2025 · Cited by 10
Kelly, S. C., Rau, C. D., Ouyang, A., Thorne, P. K., Olver, T. D., Edwards, J. C., Domeier, T. L., Padilla, J., Grisanti, L. A., Fleenor, B. S., et al. (2021) · Physiological Genomics · doi:10.1152/physiolgenomics.00093.2020 · Cited by 8
Hortegal, R. A., de Freitas, R. V., Grizante, M., Cancellier, R., Uemoto, V. R., Gun, C., Assef, J. E., Moriya, H. T., Meneghelo, R. S., Feres, F., et al. (2023) · International Journal of Cardiology · doi:10.1016/j.ijcard.2023.03.042 · Cited by 7
Oesterle, A., Bůžková, P., Pellegrini, C. N., Hirsch, C. H., Tracy, R. P., Siscovick, D. S., Djoussé, L., Mukamal, K. J., & Kizer, J. R. (2022) · The Journals of Gerontology Series A · doi:10.1093/gerona/glac229 · Cited by 8
Haddad, F., Ataam, J. A., Amsallem, M., Cauwenberghs, N., Kuznetsova, T., Rosenberg‐Hasson, Y., Zamanian, R. T., Karakikes, I., Horne, B. D., Muhlestein, J. B., et al. (2021) · Journal of Cardiac Failure · doi:10.1016/j.cardfail.2021.12.012 · Cited by 8
From Gut to Heart: Role of Indole-3-Propionic Acid in HFpEF
Vacca, A., & Schiattarella, G. G. (2024) · Circulation Research · doi:10.1161/circresaha.123.323947 · Cited by 8
Emerging trends in sacubitril/valsartan research: A bibliometric analysis of the years 1995–2021
Lai, P., Xue, J., Xie, M.-J., Ye, J.-H., Tian, K.-J., Ling, J., Zhong, W.-T., Chen, D., Zhong, Y.-M., & Liao, Y.-L. (2022) · Medicine · doi:10.1097/md.0000000000029398 · Cited by 7
Tune, J. D., Goodwill, A. G., Baker, H. E., Dick, G. M., Warne, C. M., Tucker, S. M., Essajee, S. I., Bailey, C. A., Klasing, J. A., Russell, J. J., et al. (2022) · Basic Research in Cardiology · doi:10.1007/s00395-022-00958-z · Cited by 7
Adverse cardiovascular and metabolic perturbations among older women: ‘fat-craving’ hearts
Ho, J. S., Wong, J. J., Gao, F., Wee, H. N., Teo, L. L., Ewe, S. H., Tan, R., Ching, J., Chua, K. V., Lee, L. S., et al. (2023) · Clinical Research in Cardiology · doi:10.1007/s00392-023-02156-w · Cited by 7
Plasma extracellular vesicle transcriptome as a dynamic liquid biopsy in acute heart failurePreprint
Gokulnath, P., Spanos, M., Lehmann, H. I., Sheng, Q., Rodosthenous, R. S., Chaffin, M. D., Varrias, D., Chatterjee, E., Hutchins, E. D., Li, G., et al. (2023) · medRxiv · doi:10.1101/2023.02.17.23285936 · Cited by 7
Salman, O., Zhao, L., Cohen, J. B., Dib, M., Azzo, J. D., Gan, S., Richards, M., Pourmussa, B., Doughty, R. N., Javaheri, A., et al. (2024) · Journal of the American Heart Association · doi:10.1161/jaha.123.033660 · Cited by 6
Ono, R., & Falcão, L. M. (2025) · Revista Portuguesa de Cardiologia · doi:10.1016/j.repc.2025.02.007 · Cited by 6
Magaye, R., Wang, B. H., Liu, H. R., Bailey, S., Nuon, R., Sutano, S., Nyugen, M., Kiriazis, H., Grigolon, K., Shan, L., et al. (2025) · Scientific Reports · doi:10.1038/s41598-025-08248-z · Cited by 7
Borlaug, B. A., Chirinos, J. A., Lewis, G. D., Redfield, M. M., Bertoni, A. G., Cadeiras, M., Chiamvimonvat, N., Desai, A. S., Givertz, M. M., Kass, D. A., et al. (2025) · JACC Heart Failure · doi:10.1016/j.jchf.2025.102714 · Cited by 6
Integrated left ventricular multi-omics landscape of human cardiometabolic HFpEF
Capone, F., Rommel, K., Forbes, M., Fahjen, P., Strocchi, S., Rosch, S., Wang, R., Bode, D., Nambiar, N., Eroğlu, T., et al. (2026) · Cardiovascular Research · doi:10.1093/cvr/cvag084 · Cited by 8
Chade, A., Tharp, D. L., Sitz, R., McCarthy, E. A., Shivam, K., Kazeminia, S., & Eirin, A. (2025) · American Journal of Nephrology · doi:10.1159/000543327 · Cited by 6
Peters, A. E., Ogunniyi, M. O., Hegde, S. M., Bianco, C. M., Ghafghazi, S., Hernandez, A. F., & DeVore, A. D. (2022) · Contemporary Clinical Trials · doi:10.1016/j.cct.2022.106924 · Cited by 6
Kerstens, T. P., Weerts, J., van Dijk, A. P. J., Weijers, G., Knackstedt, C., Eijsvogels, T. M. H., Oxborough, D., van Empel, V. P. M., & Thijssen, D. H. J. (2023) · European Heart Journal - Cardiovascular Imaging · doi:10.1093/ehjci/jead117 · Cited by 6
Heart Failure Medical Management in 2020
Denny, R. M., & Hummel, S. L. (2020) · Circulation Heart Failure · doi:10.1161/circheartfailure.120.007779 · Cited by 6
Guazzi, M. (2020) · Circulation Cardiovascular Imaging · doi:10.1161/circimaging.120.012001 · Cited by 6
Why We Should Care About Who Cares for Patients With Heart Failure With Preserved Ejection Fraction
Shah, S. J. (2022) · Circulation Heart Failure · doi:10.1161/circheartfailure.122.009867 · Cited by 6
Cardiac Rehabilitation and Heart Failure With Preserved Ejection Fraction
Hirashiki, A., & Shimizu, A. (2025) · Circulation Reports · doi:10.1253/circrep.cr-25-0130 · Cited by 5
Li, Y., Wang, C., Hung, C., Wu, Y., Hsu, C., Tsou, Y., Wang, C., Wu, C., Lin, P., Chang, H., et al. (2024) · PubMed Central · doi:10.6515/acs.202403_40(2).20240206a · Cited by 5
Microvascular Rarefaction in the Sinoatrial Node
Manning, D., Rivera, E. J., Rhana, P., Matsumoto, C., Fong, Z., Thai, P. N., Muñoz, M. F., Contreras, J. E., Kim, S., Grainger, N., et al. (2025) · JACC. Clinical electrophysiology · doi:10.1016/j.jacep.2025.06.007 · Cited by 5
Rane, A., Nechi, R. N., Imam, M., Zoni, R., Ndikumukiza, C., Karaye, I. M., Yunusa, I. U., & Alanzi, A. (2023) · Journal of Managed Care & Specialty Pharmacy · doi:10.18553/jmcp.2023.29.9.1045 · Cited by 5
Heart failure with preserved ejection fraction: implications for anaesthesia
Shah, A. M., Sabharwal, N. K., & Day, J. R. (2024) · BJA Education · doi:10.1016/j.bjae.2024.02.003 · Cited by 5
Schick, B. M., Dlugas, H., Czeiszperger, T. L., Matus, A. R., Bukowski, M. J., & Chung, C. S. (2021) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2021.108909 · Cited by 5
Measured Versus Estimated Resting Metabolic Rate in Heart Failure With Preserved Ejection Fraction
Anderson, T., CASCINO, T. M., Koelling, T. M., Perry, D., Grafton, G. F., Houston, D. K., Upadhya, B., Kitzman, D. W., & Hummel, S. L. (2021) · Circulation Heart Failure · doi:10.1161/circheartfailure.120.007962 · Cited by 5
Disparity and Multimorbidity in Heart Failure Patients Over the Age of 80
Błach, A., Pangle, A. K., Azhar, G., & Wei, J. Y. (2022) · Gerontology and Geriatric Medicine · doi:10.1177/23337214221098901 · Cited by 5
Takeuchi, S., Kohno, T., Goda, A., Shiraishi, Y., Saji, M., Nagatomo, Y., Tanaka, T. D., Takei, M., Nakano, S., Soejima, K., et al. (2022) · International Journal of Cardiology · doi:10.1016/j.ijcard.2022.10.024 · Cited by 5
Lo, S., Mbanze, I., Orr, J. E., DeYoung, P. N., Checkoway, H., Govo, V., Jessen, N., Damasceno, A., & Malhotra, A. (2023) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.10510 · Cited by 7
Elgebaly, S. A., Buren, C. T. V., Todd, R., Poston, R. S., Arafa, R. K., El-Khazragy, N. N., Kreutzer, D. L., Rabie, M. A., Mohamed, A. F., Ahmed, L. A., et al. (2023) · Pharmaceuticals · doi:10.3390/ph16030453 · Cited by 5
Comprehensive Investigation of Latent Pulmonary Vascular Disease
Oakland, H. T., & Shah, S. J. (2023) · JACC Heart Failure · doi:10.1016/j.jchf.2023.05.032 · Cited by 5
Dattani, A., Yeo, J. L., Brady, E. M., Cowley, A., Marsh, A.-M., Sian, M., Bilak, J. M., Graham-Brown, M. P. M., Singh, A., Arnold, J. R., et al. (2024) · Journal of Cardiovascular Magnetic Resonance · doi:10.1016/j.jocmr.2024.101120 · Cited by 5
Landsteiner, I., Stolze, L. K., Peterson, T. E., Perry, A., Lin, P., Sheng, Q., Zhao, S., Amancherla, K. V., Mi, M., Ikoma, T., et al. (2026) · Circulation · doi:10.1161/circulationaha.125.077579 · Cited by 4
Adropin protects against cardiac remodeling and metabolic dysfunction in a male mouse HFpEF model
Mushala, B. A. S., Stoner, M. W., Sharifi‐Sanjani, M., Manning, J. R., Bugga, P., Bhattarai, N., McMahon, B., Vandevender, A. M., Mullett, S. J., Kaufman, B. A., et al. (2026) · Clinical Science · doi:10.1042/cs20261501 · Cited by 4
Chang, J. W.-H., Chen, S., Hamilton, C., Shanks, J. A., Pachen, M., Pauža, A. G., George, B., & Ramchandra, R. (2024) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00548.2024 · Cited by 5
Suthahar, N., Tschöpe, C., & de Boer, R. A. (2020) · Clinical Chemistry · doi:10.1093/clinchem/hvaa255 · Cited by 4
Cine MRI characterizes HFpEF and HFrEF in post-capillary pulmonary hypertension
Lin, K., Sarnari, R., Pathrose, A., Gordon, D. Z., Blaisdell, J. A., Markl, M., & Carr, J. (2021) · European Journal of Radiology · doi:10.1016/j.ejrad.2021.109679 · Cited by 4
Chai, K., Luo, Y., Zhang, M., Liu, Y., Li, Y., Cheng, Y., Zhu, W., Chen, M., Yang, J., & Wang, H. (2023) · BMJ Open · doi:10.1136/bmjopen-2022-070766 · Cited by 4
A murine model of hypertensive heart disease in older women
Morin-Grandmont, A., Walsh‐Wilkinson, É., Thibodeau, S.-È., Boudreau, D. K., Arsenault, M., Bossé, Y., & Couët, J. (2024) · PeerJ · doi:10.7717/peerj.17434 · Cited by 4
The role of echocardiography in the diagnosis of heart failure with preserved ejection fraction
Upadhya, B., Rose, G. A., Stacey, R. B., Palma, R. A., Ryan, T., Pendyal, A., & Kelsey, A. M. (2025) · Heart Failure Reviews · doi:10.1007/s10741-025-10516-z · Cited by 5
Lang, Z., Girerd, N., Zhang, H., Xu, H., Qiu, L., Zhao, L., Hou, S., Jin, M., & Lin, H. (2025) · International Journal of Cardiology · doi:10.1016/j.ijcard.2025.133479 · Cited by 4
Tavazzi, L., Maggioni, A. P., Rapezzi, C., & Ferrari, R. (2022) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2022.02.021 · Cited by 4
Reshaping Treatment of Heart Failure with Preserved Ejection Fraction
Karamichalakis, N., Xanthopoulos, A. V., Triposkiadis, F. K., PARASKEVAIDIS, I. A., & Tsougos, E. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11133706 · Cited by 4
Weissmann, J., Charles, C. J., Richards, M., Yap, C. H., & Marom, G. (2022) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2022.1032034 · Cited by 4
Impaired Extracellular Proteostasis in Patients with Heart Failure
Gouveia, M., Teixeira, M., Schmidt, C., Lopes, M., Trindade, D., Magalhães, S., Henriques, A. G., Nunes, A., Santos, M., Vieira, S. I., et al. (2023) · Archives of Medical Research · doi:10.1016/j.arcmed.2023.02.001 · Cited by 4
Ge, R., Mao, Y., Zhao, Y., Fan, Y., Zhang, Y., Tao, X., & Yang, J. (2023) · Journal of Functional Foods · doi:10.1016/j.jff.2023.105570 · Cited by 4
Doiron, J. E., Elbatreek, M. H., Xia, H., Yu, X., Gehred, N. D., Gromova, T., Chen, J., Driver, I. H., Muraoka, N., Jensen, M., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.09.16.613349 · Cited by 4
Meyer, P., Rocca, A., Banús, J., Ogier, A. C. C., Georgantas, C., Calarnou, P., Fatima, A., Vallée, J., Deux, J., Thomas, A., et al. (2025) · Journal of the American Heart Association · doi:10.1161/jaha.125.043541 · Cited by 5
Hamilton, S., Terentyeva, R., Veress, R., Perger, F., Loyo, V., Gorr, M. W., Owusu-Sarfo, J., Quiggle, S., Györke, S., Scherr, D., et al. (2026) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2026.05.004 · Cited by 3
Pandey, A., & Butler, J. (2021) · European Journal of Heart Failure · doi:10.1002/ejhf.2313 · Cited by 3
Lyapina, I. N., Teplova, Y. E., & Martynyuk, T. V. (2023) · Russian Journal of Cardiology · doi:10.15829/1560-4071-2023-5115 · Cited by 3
Gan, S., Zhao, L., Salman, O., Wang, Z., Ebert, C., Azzo, J. D., Dib, M., Zamani, P. L., Cohen, J. B., Kammerhoff, K., et al. (2023) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2023.08.146 · Cited by 3
Levitskaya, E. S., Batyushin, М. М., Zakusilov, D. I., & Batiushina, A. M. (2024) · CARDIOVASCULAR THERAPY AND PREVENTION · doi:10.15829/1728-8800-2024-4063 · Cited by 3
Ilonze, O. J., & Mazimba, S. (2024) · Current Cardiovascular Risk Reports · doi:10.1007/s12170-024-00755-4 · Cited by 3
Ahmad, M. I., Chevli, P. A., Mirzai, S., Rikhi, R. R., Pagidipati, N. J., Slipczuk, L. N., Szklo, M., & Shapiro, M. D. (2025) · American Journal of Preventive Cardiology · doi:10.1016/j.ajpc.2025.101310 · Cited by 3
Ventricular–arterial coupling: the pressure–volume plane
Chirinos, J. A. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-91391-1.00015-7 · Cited by 3
A Computationally Efficient Approach to Simulate Heart Rate Effects Using a Whole Human Heart Model
Jiang, Y. D., Chen, S., & Guccione, J. M. (2022) · Bioengineering · doi:10.3390/bioengineering9080334 · Cited by 3
New concepts in heart failure with preserved ejection fraction and hypertension
Joury, A., Gupta, T., & Krim, S. R. (2022) · Current Opinion in Cardiology · doi:10.1097/hco.0000000000000981 · Cited by 3
Metabolomic Profiling of Cardiac Fibrosis and Steatosis in Women With or at Risk for HIV
Shitole, S. G., Naveed, M., Wang, Z., Wang, T., Kato, Y., Ambale‐Venkatesh, B., Kaplan, R. C., Tien, P. C., Anastos, K., Lazar, J., et al. (2022) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000003118 · Cited by 3
Gao, H., Patel, S., Fohtung, R. B., Cawthon, P. M., Newman, A. B., Cauley, J. A., Carbone, L. D., Chaves, P. H. M., Stein, P. K., Civitelli, R., et al. (2022) · Journal of the American Geriatrics Society · doi:10.1111/jgs.18121 · Cited by 3
Ostrominski, J. W., Claggett, B. L., Packer, M., Pfeffer, M. A., Lam, C. S. P., Zile, M. R., Desai, A. S., Jhund, P. S., Lefkowitz, M. P., McMurray, J. J. V., et al. (2023) · Journal of Cardiac Failure · doi:10.1016/j.cardfail.2023.05.003 · Cited by 3
Pepe, G., Cotugno, M., Marracino, F., Capocci, L., Pizzati, L., Forte, M., Stanzione, R., Scarselli, P., Pardo, A. D., Sciarretta, S., et al. (2023) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2023.159411 · Cited by 3
Hulot, J., Janiak, P., Boutinaud, P., Boutouyrie, P., Chézalviel-Guilbert, F., Christophe, J.-J., Cohen, A. A., Damy, T., Djadi‐Prat, J., Firat, H., et al. (2024) · Archives of cardiovascular diseases · doi:10.1016/j.acvd.2024.02.011 · Cited by 3
Comparative analysis of ventricular stiffness across species
Usui, Y., Hanashima, A., Hashimoto, K., Kimoto, M., Ohira, M., & Mohri, S. (2024) · Physiological Reports · doi:10.14814/phy2.16013 · Cited by 2
Peters, A. E., Clare, R. M., Chiswell, K., Harrington, J., Kelsey, A. M., Hernandez, A. F., Felker, G. M., Mentz, R. J., & DeVore, A. D. (2024) · ESC Heart Failure · doi:10.1002/ehf2.14777 · Cited by 3
Yang, X., Li, Z., Lei, L., Shi, X., Zhang, D., Zhou, F., Li, W., Xu, T., Liu, X., Wang, S., et al. (2025) · Journal of Medical Internet Research · doi:10.2196/67256 · Cited by 3
Sindone, A. P., Abhayaratna, W. P., Chan, A., Leung, M., Hopper, I., Amerena, J. V., Pasquale, C. G. D., Burdeniuk, C., Coats, A. J. S., & Atherton, J. J. (2025) · Heart Lung and Circulation · doi:10.1016/j.hlc.2025.08.010 · Cited by 3
Old Drug, New Trick? Oral Milrinone for Heart Failure With Preserved Ejection Fraction
Silverman, D. N., Houston, B. A., & Tedford, R. J. (2020) · Journal of the American Heart Association · doi:10.1161/jaha.120.017170 · Cited by 3
Epicardial adipose tissue and exercise intolerance in HFpEF
Lobeek, M., Gorter, T. M., & Rienstra, M. (2024) · IJC Heart & Vasculature · doi:10.1016/j.ijcha.2024.101485 · Cited by 3
Gibb, A., LaPenna, K. B., Gaspar, R. B., Latchman, N. R., Tan, Y. F., Choya-Foces, C., Doiron, J. E., Li, Z., Xia, H., Lazaropoulos, M. P., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.10.25.619450 · Cited by 3
Meyer, P., Rocca, A., Banús, J., Ogier, A. C. C., Georgantas, C., Calarnou, P., Fatima, A., Vallée, J., Deux, J., Thomas, A., et al. (2025) · medRxiv · doi:10.1101/2025.04.10.25325567 · Cited by 3
Adropin protects against cardiac remodeling and metabolic dysfunction in a mouse model of HFpEFPreprint
Mushala, B. A. S., Stoner, M. W., Sharifi‐Sanjani, M., Manning, J. R., Bugga, P., Bhattarai, N., McMahon, B., Vandevender, A. M., Mullett, S. J., Kaufman, B. A., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.05.03.652038 · Cited by 3
Advances in extracardiac mechanisms for heart failure with preserved ejection fraction.
Wang, S., & Xiao, Y. (2022) · PubMed Central · doi:10.11817/j.issn.1672-7347.2022.220310 · Cited by 2
Jo, Y. Y., Kim, S. M., Park, C., Kim, J. W., & Kwak, H. J. (2024) · Journal of Personalized Medicine · doi:10.3390/jpm14040405 · Cited by 2
McDonough, D. J. (2025) · Physiologia · doi:10.3390/physiologia5010010 · Cited by 2
Sexual dimorphism in animal models of heart failure with preserved ejection fraction
Bauer, M., Gadkari, M., Yus, M. M., Santhanam, L., & Steppan, J. (2025) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00595.2024 · Cited by 2
Alonso, W., Bills, S. E., Lundgren, S. W., Keteyian, S. J., NORMAN, J. F., Fisher, A. L., Zheng, C., Kupzyk, K. A., Wilson, F. A., Dudley, T. J., et al. (2025) · ESC Heart Failure · doi:10.1002/ehf2.15341 · Cited by 2
S100A9 inhibition ameliorates HFpEF by modulating mitochondrial fission and oxidative stress
Wang, M., Ren, B., Wu, X., Guo, J., Cao, Y., Men, L., Shi, W., Zhang, C., Lin, L., Lv, J., et al. (2025) · International Immunopharmacology · doi:10.1016/j.intimp.2025.115280 · Cited by 5
Recent Advances in Novel Modulators for Cardiac Myosin Disorders
Wang, H., Wang, M., Han, B. R., Chen, Q., & Zhang, Q. (2025) · Pharmaceutical Fronts · doi:10.1055/a-2646-1097 · Cited by 2
Liu, C., Yuan, J., Cheng, P., Yang, T., Liu, Q., Li, T., Li, C., Qu, H., & Zhou, H. (2025) · Pharmaceuticals · doi:10.3390/ph18091317 · Cited by 3
Phenotypes of Chronic Heart Failure in Patients with Preserved Ejection Fraction
Plotnikova, M. R., Аликовна, М. И., Shchekin, V. S., Khabarova, N. V., Belenkov, Y. N., & Zagidullin, N. S. (2025) · Kardiologiia · doi:10.18087/cardio.2025.10.n3021 · Cited by 2
Nebivolol in the therapeutic landscape of heart failure: Mechanisms and clinical outcomes
Ginghina, E. R., Biondi‐Zoccai, G., Vitali, A., Napoli, L. F. D., & Frati, G. (2025) · Vascular Pharmacology · doi:10.1016/j.vph.2025.107562 · Cited by 2
Rui, X., Wu, L., Ren, H., Jia, S., Dou, J., & Zhang, X. (2026) · Frontiers in Microbiology · doi:10.3389/fmicb.2026.1831648 · Cited by 2
Katogiannis, K., Efird, J. T., Dziewierz, A., Epelde, F., & Ikonomidis, I. (2026) · Medicina · doi:10.3390/medicina62061035 · Cited by 2
Levinson, R. T., Vaitinadin, N. S., Farber‐Eger, E. H., Roden, D. M., Lasko, T. A., Wells, Q. S., & Mosley, J. D. (2021) · Scientific Reports · doi:10.1038/s41598-021-97831-1 · Cited by 3
Up next: The dawn of systems biology in HFpEF research
Bode, D., Sotomayor-Flores, C., & Schiattarella, G. G. (2022) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2022.04.016 · Cited by 2
Lyapina, I. N., Teplova, Y. E., & Martynyuk, T. V. (2023) · Complex Issues of Cardiovascular Diseases · doi:10.17802/2306-1278-2022-11-4-118-129 · Cited by 2
Current Knowledge of Heart Failure with Preserved Ejection Fraction
Gherasim, L. (2023) · MAEDICA – a Journal of Clinical Medicine · doi:10.26574/maedica.2023.18.2.323 · Cited by 2
Hortegal, R. A. (2023) · ARQUIVOS BRASILEIROS DE CARDIOLOGIA - IMAGEM CARDIOVASCULAR · doi:10.36660/abcimg.20230074i · Cited by 3
Clinical differences between transthyretin cardiac amyloidosis and hypertensive heart disease
Fernández, I. G., Aguilera, J. L., Manzanares, R. G., Pericet-Rodríguez, C., Carmona-Rico, M. J., Armijo, J. P., Castillo-Dominguez, J. C., & Anguita-Sánchez, M. P. (2024) · Medicina Clínica (English Edition) · doi:10.1016/j.medcle.2023.10.011 · Cited by 2
Ma, X.-B., Liu, Y., Lv, Y.-L., & Lin, Q. (2024) · 老年心脏病学杂志：英文版 · doi:10.26599/1671-5411.2024.01.006 · Cited by 2
Metadata
- Authors
- Shah, S. J., Borlaug, B. A., Kitzman, D. W., McCulloch, A. D., Blaxall, B. C., Agarwal, R., Chirinos, J. A., Collins, S., Deo, R. C., Gladwin, M. T., Granzier, H., Hummel, S. L., Kass, D. A., Redfield, M. M., Sam, F., Wang, T. J., Desvigne-Nickens, P., & Adhikari, B. B.
- Affiliations
- Northwestern University (US)
- Mayo Clinic (US)
- Wake Forest University Health Sciences (US)
- University of California San Diego (US)
- Christ Hospital (US)
- Indiana University Indianapolis (US)
- University of Pennsylvania (US)
- Vanderbilt University (US)
- Brigham and Women's Hospital (US)
- University of Pittsburgh (US)
- University of Arizona (US)
- University of Michigan (US)
- Johns Hopkins University (US)
- Boston University (US)
- National Institutes of Health (US)
- ORCID
- Venue
- Circulation
- Published
- 2020-03-24
- Volume
- 141
- Issue
- 12
- Pages
- 1001-1026
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- PMC
- PMC7101072
- OpenAlex
- W3012616651
- Cited by
- 436
- References
- 114
- Citations by year
- 2026: 53 · 2025: 74 · 2024: 74 · 2023: 67 · 2022: 99 · 2021: 49 · 2020: 19
- FWCI
- 9.93
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Circulation (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute on Aging (R01AG018915, R01AG045551, R01AG058969, P30AG021332, U24AG059624)
- National Heart, Lung, and Blood Institute (R01HL128526, R61HL146390, R01HL118524, U01HL125175, R01HL127028, R01HL144657, R01HL104106, R01HL126638, U10HL110262, R01HL149423, DP2HL123228, R35HL135827, P01HL103455, R01HL117153, R01HL140731, P01HL094307, R01HL132551, U01HL125205, R01HL133695, R01HL121510, R01HL107577, R56HL136730, R01HL134321, R01HL125886, R01HL098032, T32HL110849)
- National Cancer Institute (K12CA090625)
- National Institute of Diabetes and Digestive and Kidney Diseases (R01DK103056, P50DK096418)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Failure Treatment and Management
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Fibrosis and Remodeling
- Keywords
- heart failure with preserved ejection fraction, research priorities, research gaps, animal models, inflammation, microvascular dysfunction, macrovascular dysfunction, fibrosis, tissue remodeling, biorepository, multiscale modeling, translational research
- MeSH terms
- Heart Failure, Humans, Research, Stroke Volume, United States, National Heart, Lung, and Blood Institute (U.S.)
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
