The DOI matches its Crossref record; 33 of the 34 references it cites were found in a registry or an index.
Prevalence and Factors Associated With Circadian Blood Pressure Patterns in Hypertensive Patients
Open accessAbstract
Ambulatory blood pressure (BP) monitoring has become useful in the diagnosis and management of hypertensive individuals. In addition to 24-hour values, the circadian variation of BP adds prognostic significance in predicting cardiovascular outcome. However, the magnitude of circadian BP patterns in large studies has hardly been noticed. Our aims were to determine the prevalence of circadian BP patterns and to assess clinical conditions associated with the nondipping status in groups of both treated and untreated hypertensive subjects, studied separately. Clinical data and 24-hour ambulatory BP monitoring were obtained from 42 947 hypertensive patients included in the Spanish Society of Hypertension Ambulatory Blood Pressure Monitoring Registry. They were 8384 previously untreated and 34 563 treated hypertensives. Twenty-four-hour ambulatory BP monitoring was performed with an oscillometric device (SpaceLabs 90207). A nondipping pattern was defined when nocturnal systolic BP dip was <10% of daytime systolic BP. The prevalence of nondipping was 41% in the untreated group and 53% in treated patients. In both groups, advanced age, obesity, diabetes mellitus, and overt cardiovascular or renal disease were associated with a blunted nocturnal BP decline ( P <0.001). In treated patients, nondipping was associated with the use of a higher number of antihypertensive drugs but not with the time of the day at which antihypertensive drugs were administered. In conclusion, a blunted nocturnal BP dip (the nondipping pattern) is common in hypertensive patients. A clinical pattern of high cardiovascular risk is associated with nondipping, suggesting that the blunted nocturnal BP dip may be merely a marker of high cardiovascular risk.
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“Furthermore, variation in the day–night blood pressure pattern appears to be an important predictor of both target organ damage and cardiovascular events 68.”
From The Circadian Syndrome: is the Metabolic Syndrome and much more! (2019) · cites this paper as [68]
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2013 ESH/ESC Guidelines for the management of arterial hypertension
Authors Task Force Members, Mancia, G., Fagard, R., Narkiewicz, K., Redon, J., Zanchetti, A., Böhm, M., Christiaens, T., Cífková, R., Backer, G. D., et al. (2013) · European Heart Journal · doi:10.1093/eurheartj/eht151 · Cited by 13,739
Self-citationGuidelines Committee (2003) · Journal of Hypertension · doi:10.1097/00004872-200306000-00001 · Cited by 3,015
Mancia, G., Rosei, E. A., Cífková, R., DeBacker, G., Erdine, S. E., Fagard, R., Farsang, C., Heagerty, A. M., Kawecka-Jaszcs, K., Kiowski, W., et al. (2003) · Lirias (KU Leuven) · doi:10.1097/01.hjh.0000059051.65882.32 · Cited by 2,601
Self-citationAmbulatory blood pressure. An independent predictor of prognosis in essential hypertension.
Verdecchia, P., Porcellati, C., Schillaci, G., Borgioni, C., Ciucci, A., Battistelli, M., Guerrieri, M., Gatteschi, C., Zampi, I., Santucci, A., et al. (1994) · Hypertension · doi:10.1161/01.hyp.24.6.793 · Cited by 1,671
O'Brien, E., Asmar, R., Beilin, L., Imai, Y., Mallion, J.-M., Mancia, G., Mengden, T., Myers, M., Padfield, P., Palatini, P., et al. (2003) · Journal of Hypertension · doi:10.1097/00004872-200305000-00001 · Cited by 1,655
Self-citationStaessen, J. A. (1999) · JAMA · doi:10.1001/jama.282.6.539 · Cited by 1,592
Dolan, E., Stanton, A., Thijs, L., Hinedi, K., Atkins, N., McClory, S., Hond, E. D., McCormack, P., Staessen, J. A., & O’Brien, E. (2005) · Hypertension · doi:10.1161/01.hyp.0000170138.56903.7a · Cited by 1,227
Prognostic Value of Ambulatory Blood-Pressure Recordings in Patients with Treated Hypertension
Clement, D. L., De Buyzere, M. L., De Bacquer, D. A., de Leeuw, P. W., Duprez, D. A., Fagard, R. H., Gheeraert, P. J., Missault, L. H., Braun, J. J., Six, R. O., et al. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa022273 · Cited by 1,085
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Measurement of Blood Pressure in Humans: A Scientific Statement From the American Heart Association
Muntner, P., Shimbo, D., Carey, R. M., Charleston, J. B., Gaillard, T., Misra, S., Myers, M. G., Ogedegbe, G., Schwartz, J. E., Townsend, R. R., et al. (2019) · Hypertension · doi:10.1161/hyp.0000000000000087 · Cited by 1,512
de la Sierra, A., Segura, J., Banegas, J. R., Gorostidi, M., de la Cruz, J. J., Armario, P., Oliveras, A., & Ruilope, L. M. (2011) · Hypertension · doi:10.1161/hypertensionaha.110.168948 · Cited by 809
Self-citationHermida, R. C., Ayala, D. E., Mojón, A., & Fernández, J. R. (2010) · Chronobiology International · doi:10.3109/07420528.2010.510230 · Cited by 608
“Despite these documented advantages of bedtime hypertension chronotherapy, most clinicians and pharmacists continue to advise patients, including those requiring combination therapies, to ingest their once-a-day BP-lowering medications in the morning (de la Sierra et al., 2009; Salles et al., 2008).”
BackgroundResultEmpagliflozin Reduces Blood Pressure in Patients With Type 2 Diabetes and Hypertension
Tikkanen, I., Narko, K., Zeller, C., Green, A., Salsali, A., Broedl, U. C., & Woerle, H. J. (2015) · Diabetes Care · doi:10.2337/dc14-1096 · Cited by 468
“nocturnal BP decline in patients with hypertension is more frequent in patients with obesity, diabetes, and overt cardiovascular or renal disease and associated with a higher cardiovascular risk (27).”
BackgroundThe Circadian Syndrome: is the Metabolic Syndrome and much more!
Zimmet, P., Alberti, K. G. M. M., Stern, N., Bilu, C., El‐Osta, A., Einat, H., & Kronfeld‐Schor, N. (2019) · Journal of Internal Medicine · doi:10.1111/joim.12924 · Cited by 387
Metadata
- Authors
- de la Sierra, A., Redon, J., Banegas, J. R., Segura, J., Parati, G., Gorostidi, M., de la Cruz, J. J., Sobrino, J., Llisterri, J. L., Alonso, J., Vinyoles, E., Pallarés, V., Sarría, A., Aranda, P., & Ruilope, L. M.
- Affiliations
- From the Hypertension Unit (A.d.l.S.), Hospital Clínic, University of Barcelona, Barcelona, Spain; Hypertension Unit, Hospital Clínico (J.R.), University of Valencia and Centro de Investigación Biomédica au Red (CIBER) of Obesity and Nutritional Disorders, Valencia, Spain; Department of Preventive Medicine and Public Health (J.R.B., J.J.d.l.C.), Autonomous University and CIBER of Epidemiology and Public Health, Madrid, Spain; Hypertension Unit (J.Segura, L.M.R.), Hospital 12 de Octubre, Madrid,...
- Universidad Complutense de Madrid (ES)
- Universitat Autònoma de Barcelona (ES)
- ORCID
- Venue
- Hypertension
- Published
- 2009-03
- Volume
- 53
- Issue
- 3
- Pages
- 466-472
- ISSN
- 0194-911X (ISSN-L)
- 1524-4563
- OpenAlex
- W2137218363
- Semantic Scholar
- 1acddbb4ed2a4020230b89f1921ced018ea70f76
- Cited by
- 379
- References
- 34
- Citations by year
- 2026: 14 · 2025: 17 · 2024: 24 · 2023: 19 · 2022: 11 · 2021: 17 · 2020: 22 · 2019: 22 · 2018: 22 · 2017: 19 · 2016: 17 · 2015: 28 · 2014: 28 · 2013: 23 · 2012: 31
- FWCI
- 20.70
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Hypertension (publishedVersion)
- PubMed (publishedVersion)
- BOA (University of Milano-Bicocca) (submittedVersion)
- RISalud Institutional Health Repository of Andalucía (submittedVersion, other-oa)
- Zenodo (CERN European Organization for Nuclear Research) (submittedVersion, cc-by)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
- Health Sciences › Nursing › Nutrition and Dietetics › Sodium Intake and Health
- Keywords
- circadian blood pressure rhythm, non-dipping blood pressure, ambulatory blood pressure monitoring, nocturnal blood pressure dipping, cardiovascular risk, antihypertensive drugs, obesity, diabetes mellitus, kidney disease, untreated hypertension
- MeSH terms
- Adult, Aged, Antihypertensive Agents, Blood Pressure, Circadian Rhythm, Female, Humans, Hypertension, Male, Middle Aged, Registries, Spain, Cohort Studies, Prevalence, Linear Models, Blood Pressure Monitoring, Ambulatory
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