The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
Long-Term Weight Loss From Lifestyle Intervention Benefits Blood Pressure?: A Systematic Review
Abstract
Weight gain may increase blood pressure. Weight loss may reduce this. Reviews have considered the long-term effects of weight loss but are related mainly to more obese participants often on obesity medication and/or undergoing obesity surgery. This systematic review, based on lifestyle interventions for adults (18 to 65 years) with mean baseline BMI of <35 kg/m 2 , links weight change to blood pressure difference. A systematic review of studies reporting weight differences and blood pressure outcomes, published between 1990 and 2008 with follow-up of ≥2 years identified 8 clinical trials or controlled before and after studies (represented by 9 articles) and 8 cohort studies. Differences ranged from −11 to +4kg for weight, −7 to +2.2 mm Hg for diastolic blood pressure and −13 to +6.1 mm Hg for systolic blood pressure. For this population group, no quantifiable relationship between weight and diastolic blood pressure difference was found, possibly because of small weight losses, differing weight status responses, or because pharmacologically controlled hypertension masked weight loss influences. Systolic differences were in line with previous reviews of 1 kg:1 mm Hg relationship, but only for follow-up periods of 2 to 3 years, possibly reflecting the fact that regardless of maintained weight loss, blood pressure often reverts back to higher levels. Lifestyle interventions for weight and blood pressure are limited in this target group, and there has been no exploration of successful intervention components. An individual patient data analysis may uncover baseline and medication effects, explore differences between weight groups, and may identify successful components. Such an analysis would enable effective development of preventative interventions for both hypertension and obesity.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Systematic reviews consistently report a decrease in SBP of about 1 mm Hg per kg of weight loss with follow-up of 2 to 3 years.[111][112][113][114]”
From Obesity‐Related Hypertension: Pathogenesis, Cardiovascular Risk, and Treatment: A Position Paper of The Obesity Society and the American Society of Hypertension (2013) · cites this paper as [113]
Citations
Cites
Influence of Weight Reduction on Blood Pressure: A Meta-Analysis of Randomized Controlled Trials
Neter, J. E., Stam, B. E., Kok, F. J., Grobbee, D. E., & Geleijnse, J. M. (2003) · Hypertension · doi:10.1161/01.hyp.0000094221.86888.ae · Cited by 1,391
Eriksson, K. F., & Lindg�rde, F. (1991) · Diabetologia · doi:10.1007/bf00400196 · Cited by 1,092
Avenell, A., Broom, J., Brown, T., Poobalan, A., Aucott, L., Stearns, S., Smith, W., Jung, R., Campbell, M., & Grant, A. (2004) · Health Technology Assessment · doi:10.3310/hta8210 · Cited by 1,041 · cited 2×
“Welty(26)** Medical center Participants with 1 cardio risk factor or CHD (31) 79 7.”
BackgroundSelf-citationHaskell, W. L., Alderman, E. L., Fair, J. M., Maron, D. J., Mackey, S. F., Superko, H. R., Williams, P. T., Johnstone, I. M., Champagne, M. A., & Krauss, R. M. (1994) · Circulation · doi:10.1161/01.cir.89.3.975 · Cited by 884
Mean body weight, height, and body mass index, United States 1960-2002.
Ogden, C. L., Fryar, C. D., Carroll, M. D., & Flegal, K. M. (2004) · PubMed · Cited by 717
Sjöström, C. D., Lissner, L., Wedel, H., & Sjöström, L. (1999) · Obesity Research · doi:10.1002/j.1550-8528.1999.tb00436.x · Cited by 685
Introduction to Probability and Mathematical Statistics.
Franck, W. E., Bain, L. J., & Engelhardt, M. (1988) · Journal of the American Statistical Association · doi:10.2307/2288954 · Cited by 479
Metabolic and weight-loss effects of a long-term dietary intervention in obese patients
Ditschuneit, H. H. M., Flechtner‐Mors, M., Johnson, T. D., & Adler, G. (1999) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/69.2.198 · Cited by 304
Flechtner‐Mors, M., Ditschuneit, H. H. M., Johnson, T. D., Suchard, M. A., & Adler, G. (2000) · Obesity Research · doi:10.1038/oby.2000.48 · Cited by 285
Cited by
Sorted by citations
Whelton, P. K., Carey, R. M., Aronow, W. S., Casey, D. E., Collins, K. J., Dennison Himmelfarb, C., DePalma, S. M., Gidding, S., Jamerson, K. A., Jones, D. W., et al. (2018) · Hypertension · doi:10.1161/hyp.0000000000000065 · Cited by 7,391
Whelton, P. K., Carey, R. M., Aronow, W. S., Casey, D. E., Collins, K. J., Dennison Himmelfarb, C., DePalma, S. M., Gidding, S., Jamerson, K. A., Jones, D. W., et al. (2018) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.11.006 · Cited by 6,616
Whelton, P. K., Carey, R. M., Aronow, W. S., Casey, D. E., Collins, K. J., Dennison Himmelfarb, C., DePalma, S. M., Gidding, S., Jamerson, K. A., Jones, D. W., et al. (2018) · Circulation · doi:10.1161/cir.0000000000000596 · Cited by 1,127
Landsberg, L., Aronne, L. J., Beilin, L. J., Burke, V., Igel, L. I., Lloyd‐Jones, D., & Sowers, J. (2013) · The Journal of Clinical Hypertension · doi:10.1111/jch.12049 · Cited by 528
Leggio, M., Lombardi, M., Caldarone, E., Severi, P., D’Emidio, S., Armeni, M., Bravi, V., Bendini, M. G., & Mazza, A. (2017) · Hypertension Research · doi:10.1038/hr.2017.75 · Cited by 319
Landsberg, L., Aronne, L. J., Beilin, L. J., Burke, V., Igel, L. I., Lloyd‐Jones, D. M., & Sowers, J. R. (2012) · Obesity · doi:10.1002/oby.20181 · Cited by 296
Warren-Findlow, J., Seymour, R. B., & Brunner Huber, L. R. (2012) · Journal of Community Health · doi:10.1007/s10900-011-9410-6 · Cited by 239
“African Americans may not realize how their weight status influences their blood pressure, and that losing or maintaining their weight as part of a comprehensive chronic disease management strategy can have a positive effect on high blood pressure [46].”
BackgroundExpert panel report: Guidelines (2013) for the management of overweight and obesity in adults
(2014) · Obesity · doi:10.1002/oby.20660 · Cited by 257
Hendricks, E. J., Greenway, F. L., Westman, E. C., & Gupta, A. K. (2011) · Obesity · doi:10.1038/oby.2011.94 · Cited by 97
“Multiple studies have shown that weight loss induced by caloric restriction and behavior change without antiobesity pharmacotherapy is associated with decreased blood pressure (15).”
BackgroundBadrov, M. B., Horton, S., Millar, P., & McGowan, C. (2013) · Psychophysiology · doi:10.1111/psyp.12031 · Cited by 93
Lifestyle health promotion interventions for the nursing workforce: a systematic review.
Chan, C., & Perry, L. (2012) · Journal of Clinical Nursing · doi:10.1111/j.1365-2702.2012.04213.x · Cited by 104
Weight maintenance: challenges, tools and strategies for primary care physicians
Soleymani, T., Daniel, S., & Garvey, W. T. (2015) · Obesity Reviews · doi:10.1111/obr.12322 · Cited by 98
“Sustained weight loss (3 kg lost over 2–3 years) leads to reductions in blood pressure (32,33).”
BackgroundHealth Benefits of Long-Term Weight-Loss Maintenance
Rueda‐Clausen, C. F., Ogunleye, A. A., & Sharma, A. M. (2015) · Annual Review of Nutrition · doi:10.1146/annurev-nutr-071714-034434 · Cited by 93
Gamage, D. G., Riddell, M. A., Joshi, R., Thankappan, K. R., Chow, C. K., Oldenburg, B. F., Evans, R. G., Mahal, A. S., Kalyanram, K., Kartik, K., et al. (2020) · PLoS Medicine · doi:10.1371/journal.pmed.1002997 · Cited by 85
Safety of Aesthetic Surgery in the Overweight Patient: Analysis of 127,961 Patients
Gupta, V., Winocour, J. S., Rodriguez-Feo, C. L., Bamba, R., Shack, R. B., Grotting, J. C., & Higdon, K. K. “. (2016) · Aesthetic Surgery Journal · doi:10.1093/asj/sjv268 · Cited by 80
Genetic Predisposition to Higher Blood Pressure Increases Coronary Artery Disease Risk
Lieb, W., Jansen, H., Loley, C., Pencina, M. J., Nelson, C. P., Newton‐Cheh, C., Kathiresan, S., Reilly, M. P., Assimes, T. L., Boerwinkle, E., et al. (2013) · Hypertension · doi:10.1161/hypertensionaha.111.00275 · Cited by 77
Predictors of Hypertension Remission and Recurrence After Bariatric Surgery
Benaiges, D., Sagué, M., Roux, J. A. F., Pedro‐Botet, J., Ramón, J. M., Villatoro, M., Chillarón, J. J., Pera, M., Más, A., Grande, L., et al. (2015) · American Journal of Hypertension · doi:10.1093/ajh/hpv153 · Cited by 77
Exercise in Aging: Its Important Role in Mortality, Obesity and Insulin Resistance
Ryan, A. S. (2010) · Aging Health · doi:10.2217/ahe.10.46 · Cited by 78
“Readers are encouraged to look elsewhere for additional reviews on exercise and hypertension and dyslipidemia [30-33].”
BackgroundWeight Loss Medications in the Treatment of Obesity and Hypertension
Cohen, J. B., & Gadde, K. M. (2019) · Current Hypertension Reports · doi:10.1007/s11906-019-0915-1 · Cited by 81
Impact of sodium–glucose cotransporter 2 inhibitors on blood pressure
Reed, J. W. (2016) · Vascular Health and Risk Management · doi:10.2147/vhrm.s111991 · Cited by 67
Exenatide therapy in insulin-treated type 2 diabetes and obesity
Nayak, U. A., Govindan, J. P., Baskar, V., Kalupahana, D., & Singh, B. M. (2010) · QJM · doi:10.1093/qjmed/hcq112 · Cited by 62
Chacón, F., Mora, F., Gervás-Ríos, A., & Gilaberte, I. (2011) · Annals of General Psychiatry · doi:10.1186/1744-859x-10-22 · Cited by 61
“A review of lifestyle interventions with intentional weight loss showed that those lifestyle interventions were effective in reducing systolic blood pressure, although the evidence for diastolic blood pressure was less convincing [80].”
BackgroundHui, F., Zhang, Y., Ren, T., Li, X., Zhao, M., & Zhao, Q. (2018) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-018-2593-3 · Cited by 55
Sarvottam, K., & Yadav, R. K. (2014) · Europe PMC (PubMed Central) · Cited by 51
The effects of lifestyle interventions in dynapenic-obese postmenopausal women
Sénéchal, M., Bouchard, D. R., Dionne, I. J., & Brochu, M. (2012) · Menopause · doi:10.1097/gme.0b013e318248f50f · Cited by 48
Impact of Adiposity on Incident Hypertension Is Modified by Insulin Resistance in Adults
Zhang, T., Zhang, H., Li, S., Li, Y., Liu, Y., Fernandez, C., Harville, E. W., Bazzano, L., He, J., & Chen, W. (2015) · Hypertension · doi:10.1161/hypertensionaha.115.06509 · Cited by 43
“56 The association between adiposity and hypertension has been well established in observational studies, and intervention studies have also showed that weight loss can lower blood pressure (BP) in obese hypertensives.(4) In United States, the prevalence of hypertension in obese adults is 40.”
BackgroundMetformin-based treatment for obesity-related hypertension
He, H., Zhao, Z., Chen, J., Ni, Y., Zhong, J., Yan, Z., Li, Y., Liu, D., Pletcher, M. J., & Zhu, Z. (2012) · Journal of Hypertension · doi:10.1097/hjh.0b013e328353e249 · Cited by 40
“Although lifestyle modification is the preferred intervention, a recent systematic review raised doubts about the benefits of long-term weight loss from lifestyle interventions on blood pressure [8], and the European Society of Hypertension Working Group also found an inconsistent blood pressure response to surgical a…”
Modern Obesity Pharmacotherapy: Weighing Cardiovascular Risk and Benefit
Cunningham, J. W., & Wiviott, S. D. (2014) · Clinical Cardiology · doi:10.1002/clc.22304 · Cited by 35
Ziv, A., Vogel, O. G., Keret, D., Pintov, S., Bodenstein, E., Wolkomir, K., Doenyas‐Barak, K., Mirovski, Y., & Efrati, S. (2013) · Journal of Human Hypertension · doi:10.1038/jhh.2013.29 · Cited by 37
Tsujimoto, T., Sairenchi, T., Iso, H., Irie, F., Yamagishi, K., Tanaka, K., Muto, T., & Ota, H. (2012) · Journal of Hypertension · doi:10.1097/hjh.0b013e328352b879 · Cited by 34
Totsikas, C., Röhm, J., Kantartzis, K., Thamer, C., Rittig, K., Machann, J., Schick, F., Hansel, J., Niess, A. M., Fritsche, A., et al. (2011) · Journal of Hypertension · doi:10.1097/hjh.0b013e3283469910 · Cited by 29
Reynolds, K., Barton, L. J., Basu, A., Fischer, H. J., Arterburn, D. E., Barthold, D., Courcoulas, A. P., Crawford, C. L., Kim, B. B., Fedorka, P. N., et al. (2021) · Hypertension · doi:10.1161/hypertensionaha.120.16934 · Cited by 29
Very low-calorie ketogenic diet (VLCKD): an antihypertensive nutritional approach
Barrea, L., Verde, L., Santangeli, P., Lucà, S., Docimo, A., Savastano, S., Colao, A., & Muscogiuri, G. (2023) · Journal of Translational Medicine · doi:10.1186/s12967-023-03956-4 · Cited by 29
Obesity-related Kidney Disease
Snyder, S., Turner, G. A., & Turner, A. (2014) · Primary Care Clinics in Office Practice · doi:10.1016/j.pop.2014.08.008 · Cited by 27
“On average, for each kilogram of weight loss, an individual’s blood pressure was reduced by approximately 1 mm Hg.(38) More than 85% of patients with CKD have hypertension.”
BackgroundSarzani, R., Bordicchia, M., Spannella, F., Dessı̀-Fulgheri, P., & Fedecostante, M. (2014) · High Blood Pressure & Cardiovascular Prevention · doi:10.1007/s40292-014-0054-3 · Cited by 30
Hu, J., Chu, G.-P., Huang, F., Zhou, Y., Teng, C.-G., Yang, H., & Shen, H. (2016) · International Journal of Cardiology · doi:10.1016/j.ijcard.2016.07.217 · Cited by 27
“28) for DBPwhen expressed per kilogram of weight loss [23]; another review based on lifestyle interventions for adults (18 to 65 years) indicated that a 3-kg weight loss may reduce BP and an individual with a 5 kg weight loss may expect on average a”
BackgroundSahebkar, A., Simental‐Mendía, L. E., Kovanen, P. T., Pedone, C., Simental-Mendía, M. A., & Cicero, A. F. G. (2017) · Journal of the American Society of Hypertension · doi:10.1016/j.jash.2017.12.002 · Cited by 27
Mackey, R. H., Belle, S. H., Courcoulas, A. P., Dakin, G. F., Deveney, C. W., Flum, D. R., Garcia, L., King, W. C., Kuller, L. H., Mitchell, J. E., et al. (2012) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2012.05.054 · Cited by 25
Xie, Z., He, Z., Ye, Y., & Mao, Y. (2022) · Nutrition · doi:10.1016/j.nut.2022.111764 · Cited by 24
Lih, A., Pereira, L., Bishay, R. H., Zang, J., Omari, A., Atlantis, E. E., & Kormas, N. (2015) · Journal of Diabetes Research · doi:10.1155/2015/729567 · Cited by 24
Gaining pounds by losing pounds: preferences for lifestyle interventions to reduce obesity
Ryan, M., Yi, D., Avenell, A., Douglas, F., Aucott, L. S., van Teijlingen, E., & Vale, L. D. (2014) · Health Economics Policy and Law · doi:10.1017/s1744133114000413 · Cited by 23
Self-citationAdvances in Nutrition Science and Integrative Physiology: Insights From Controlled Feeding Studies
Davy, K. P., & Davy, B. M. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.01341 · Cited by 25
“The latter was critical to the success of the study given the well-documented impact of weight loss on BP (Aucott et al., 2009).”
BackgroundLemp, J. M., Nuthanapati, M. P., Bärnighausen, T., Vollmer, S., Geldsetzer, P., & Jani, A. R. (2022) · Journal of the Royal Society of Medicine · doi:10.1177/01410768221077381 · Cited by 22
Ittermann, T., Werner, N., Lieb, W., Merz, B., Nöthlings, U., Kluttig, A., Tiller, D., Greiser, K. H., Vogt, S., Thorand, B., et al. (2018) · International Journal of Cardiology · doi:10.1016/j.ijcard.2018.09.035 · Cited by 20
“Most of the previous studies on the association between changes in body weight and changes in arterial blood pressure did not consider other markers such as waist circumference, FM, or FFM [11, 12, 23-25].”
BackgroundResultInfluentialSahli, J., Maatoug, J., Harrabi, I., Fredj, S. B., Dendana, E., & Ghannem, H. (2016) · Global Heart · doi:10.1016/j.gheart.2016.01.001 · Cited by 17
“The relationship between obesity and hypertension was well established [20], and weight-loss can lower blood pressure [21].”
BackgroundZhao, Y. K., Liu, Y., Sun, H., Sun, X., Yin, Z., Li, H., Ren, Y., Wang, B., Zhang, D., Liu, X., et al. (2018) · Nutrition · doi:10.1016/j.nut.2018.02.020 · Cited by 20
Genetic Susceptibility, Dietary Protein Intake, and Changes of Blood Pressure
Sun, D., Zhou, T., Li, X., Heianza, Y., Liang, Z., Bray, G. A., Sacks, F. M., & Qi, L. (2019) · Hypertension · doi:10.1161/hypertensionaha.119.13510 · Cited by 21
Longitudinal Changes in Physical Capacity Over 20 Years in Athletes With Spinal Cord Injury
Shiba, S., Okawa, H., Uenishi, H., Koike, Y., Yamauchi, K., Asayama, K., Nakamura, T., & Tajima, F. (2010) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2010.04.024 · Cited by 18
Espeland, M. A., Probstfield, J., Hire, D., Redmon, J. B., Evans, G. W., Coday, M., Lewis, C. E., Johnson, K., Wilmoth, S. K., Bahnson, J. L., et al. (2015) · American Journal of Hypertension · doi:10.1093/ajh/hpu292 · Cited by 18
Mbuthia, G. W., Mwangi, J., Magutah, K., Oguta, J. O., Ngure, K., & McGarvey, S. T. (2024) · PLoS ONE · doi:10.1371/journal.pone.0293791 · Cited by 20
“This study is registered in the Pan African Clinical Trial Registry database, registration number PACTR202309530525257.”
Does Hypertension Impact 24-Hour Urine Parameters in Patients With Nephrolithiasis?
Hartman, C., Friedlander, J. I., Moreira, D. M., Leavitt, D., Hoenig, D. M., Smith, A. D., & Okeke, Z. (2015) · Urology · doi:10.1016/j.urology.2014.12.013 · Cited by 17
Lifestyle Intervention Strategies for the Prevention and Treatment of Hypertension: A Review
Brill, J. B. (2011) · American Journal of Lifestyle Medicine · doi:10.1177/1559827610392873 · Cited by 21
“Two meta-analyses of clinical trials on the effects of weight reduction on lowering BP support the efficacy of weight loss intervention for both the prevention and treatment of HTN, particularly in the short term.(25,26) The Aucott et al(25) analysis reviewed 8 clinical trials and 8 cohort studies to determine the imp…”
BackgroundAndrade, F. C. D., Vazquez‐Vidal, I., Flood, T. L., Aradillas-García, C., Morales, J. M. V., Medina-Cerda, E., & Terán-Garcı́a, M. (2012) · Public Health · doi:10.1016/j.puhe.2012.02.005 · Cited by 17
Liu, L., Guo, J., Jiao, X., & You, L. (2024) · Hypertension Research · doi:10.1038/s41440-024-01892-4 · Cited by 21
Intra-abdominal fat accumulation is a hypertension risk factor in young adulthood
Takeoka, A., Tayama, J., Yamasaki, H., Kobayashi, M., Ogawa, S., Saigo, T., Kawano, H., Abiru, N., Hayashida, M., Maeda, T., et al. (2016) · Medicine · doi:10.1097/md.0000000000005361 · Cited by 17
“A systematic review evaluated the relationship between weight change and BP difference in adults.([36]) The relationship found between weight and SBP difference was 1kg:1mmHg.”
Long-term changes in body weight are associated with changes in blood pressure levels
Markus, M. R. P., Ittermann, T., Baumeister, S., Troitzsch, P., Schipf, S., Lorbeer, R., Aumannn, N., Wallaschofski, H., Dörr, M., Rettig, R., et al. (2014) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2014.10.011 · Cited by 16
Beaulac, J., & Sandre, D. (2016) · Perspectives in Public Health · doi:10.1177/1757913916653425 · Cited by 18
Jafari, F., Shahriari, M., Sabouhi, F., Khosravi, A., & Eghbali‐Babadi, M. (2016) · PubMed Central · Cited by 15
Seven, E., Husemoen, L. L. N., Wachtell, K., Ibsen, H., Linneberg, A. R., & Jeppesen, J. (2014) · Journal of Hypertension · doi:10.1097/hjh.0000000000000317 · Cited by 15
“A short-term effect of 1mmHg drop per 1 kg weight loss have been reported [27], but reports indicate that the effect diminishes with time and concomitant difficulties in weight loss maintenance results in less-pronounced long-term reductions [28,29].”
BackgroundWeight Loss Therapies and Hypertension Benefits
Katsi, V. K., Manta, E., Fragoulis, C., & Tsioufis, K. P. (2024) · Biomedicines · doi:10.3390/biomedicines12102293 · Cited by 16
“…these two variables is linear, as it has been shown that a 1 kg reduction in body weight through lifestyle interventions can lead to a 1 mmHg reduction in systolic blood pressure levels [19,20 The underlying pathophysiological mechanisms for this association are likely based on adipose tissue.”
BackgroundLong-Term Effectiveness of Non-Drug Recommendations to Treat Hypertension in a Clinical Setting
Riegel, G. R. C., Moreira, L. B., Fuchs, S. C., Gus, M., Nunes, G., Correa, V. A., Wiehe, M., Goncalves, C. C., Fernandes, F. S., & Fuchs, F. D. (2012) · American Journal of Hypertension · doi:10.1038/ajh.2012.103 · Cited by 14
Brissette, C., Jenkins, A. L., Choleva, L., & Vuksan, V. V. V. (2013) · Canadian Journal of Diabetes · doi:10.1016/j.jcjd.2013.08.183 · Cited by 17
Darviri, C., Artemiadis, A., Protogerou, A. D., Soldatos, P., Kranioutou, C., Vasdekis, S. N., Varvogli, L., Nasothimiou, E., Vasilopoulou, E., Karantzi, E., et al. (2015) · Journal of Human Hypertension · doi:10.1038/jhh.2015.99 · Cited by 13
Sympathetic Activation in Resistant Hypertension: Theory and Therapy
Oliva, R., & Bakris, G. L. (2014) · Seminars in Nephrology · doi:10.1016/j.semnephrol.2014.08.009 · Cited by 13
Bishay, R. H., Omari, A., Zang, J., Lih, A., & Kormas, N. (2013) · Clinical Diabetes · doi:10.2337/diaclin.31.1.14 · Cited by 12
Marin‐Couture, É., Moulin, J.-A., Thibault, A.-S., Poirier, P., Després, J., Gallant, A., Lamarre, V., Alméras, N., Lemieux, I., Chabot, C., et al. (2024) · American Journal of Lifestyle Medicine · doi:10.1177/15598276241242013 · Cited by 12
“The current literature demonstrates the bene fi cial relationship between weight loss and BP lowering, 48,49 indicating that a weight loss of ∼ 8 kg is associated with a clinically signi fi cant reduction in both SBP and DBP of 7-10 mm Hg and of 6-7 mm Hg, respectively.”
Weight Loss and Reduction of Blood Pressure and Hypertension
Kuller, L. H. (2009) · Hypertension · doi:10.1161/hypertensionaha.109.138891 · Cited by 10
Partnering with Patients to Improve Therapeutic Outcomes: Incretin-Based Therapy for Type 2 Diabetes
Nadeau, D. A. (2010) · Postgraduate Medicine · doi:10.3810/pgm.2010.05.2137 · Cited by 9
Sosner, P., Bosquet, L., Herpin, D., Guilbeault, V., Latour, É., Paquette-Tannir, L., Juneau, M., Nigam, A., & Gayda, M. (2016) · Journal of Clinical Hypertension · doi:10.1111/jch.12829 · Cited by 10
“While meta-analysis suggested that, for 1 kg of weight loss, 1 mm Hg reduction should be possible for both SBP/DBP,(19) linkage of weight to BP changes have been far from obvious in reviews focusing on long-term programs.(20) Some heterogeneity between the different studies and less responsive changes were reported in…”
BackgroundLee, E.-W., Kim, H.-S., Yoo, B., Lee, E., & Park, J. H. (2022) · Iranian Journal of Public Health · doi:10.18502/ijph.v51i3.8939 · Cited by 8
“compliance (34-36), the latter of reported to be higher when health literacy and self-efficacy are high (37).”
BackgroundHonda, T., Ishida, Y., Oda, M., Noguchi, K., Chen, S., Sakata, S., Oishi, E., Furuta, Y., Yoshida, D., Hirakawa, Y., et al. (2021) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.59394 · Cited by 8
Ghammam, R., Maatoug, J., Harrabi, I., Fredj, S. B., Zammit, N., Laatikainen, T. K., Vartiainen, E. A., Neupane, D., & Ghannem, H. (2022) · Journal of Human Hypertension · doi:10.1038/s41371-022-00672-2 · Cited by 7
“What is known about topic Health education intervention at the community level was found to be effective in reducing blood pressure in a LMIC.”
BackgroundDiet to Stop Hypertension: Should Fats be Included?
Nestel, P. J., & Mori, T. A. (2024) · Current Hypertension Reports · doi:10.1007/s11906-024-01310-7 · Cited by 7
“Conversely weight loss results in BP reduction although the relationship is not linear and weight regain is common [7, 8].”
BackgroundGepner, Y., Goldstein, N., Shelef, I., Schwarzfuchs, D., Zelicha, H., Meir, A. Y., Tsaban, G., & Grossman, E. (2021) · Journal of General Internal Medicine · doi:10.1007/s11606-021-06655-2 · Cited by 9
Clinical Practice Guideline for the Management of Overweight and Obesity in Adults in Saudi Arabia
Alshaikh, A., Al-Jedai, A. H., Alfadda, A. A., Al-Robayan, A. A., Bawahab, A., Abo’ouf, S., Sultan, A., Alhozali, A. M., Bawazeer, M. A., Sheshah, E., et al. (2022) · International Journal of Clinical Medicine · doi:10.4236/ijcm.2022.1312045 · Cited by 8
Evaluation of pharmacy-led weight management service to minimise the risk of cardiovascular disease
Peletidi, A., & Kayyali, R. (2021) · Journal of Pharmaceutical Policy and Practice · doi:10.1186/s40545-021-00338-3 · Cited by 8
Recomendaciones preventivas vasculares. Actualización PAPPS 2024
Orozco‐Beltrán, D., Brotons-Cuixart, C., Banegas, J. R., Gil-Guillén, V. F., Cuenca, A. M. C., Martín-Rioboó, E., Jordá-Baldó, A., Vicuña, J., & Navarro-Pérez, J. (2024) · Atención Primaria · doi:10.1016/j.aprim.2024.103123 · Cited by 9
Ganho de peso na vida adulta: preditor da hipertensão arterial?
Peixoto, M. D. R. G., Cordeiro, M. D. M., Ferreira, V. R., Cardoso, C. K. D. S., & Crispim, P. A. A. (2017) · Cadernos Saúde Coletiva · doi:10.1590/1414-462x201700010023 · Cited by 6
Jafari, F., Shahriari, M., Sabouhi, F., Khosravi, A., & Eghbali‐Babadi, M. (2020) · PubMed Central · doi:10.22122/arya.v16i1.1502 · Cited by 6
Phentermine therapy for obesity does not elevate blood pressure
Hendricks, E. J., & Rothman, R. B. (2011) · Diabetes Obesity and Metabolism · doi:10.1111/j.1463-1326.2011.01435.x · Cited by 6
“Average blood pressures are known to decline when obese patients lose weight without pharmacotherapy [2].”
BackgroundEffects of long- and short-term body mass index changes on incident hypertension are different
Xu, J., Guo, R., Xie, Y., Zheng, J., Wang, Y., Dai, Y., Sun, Z., Xing, L., Zhang, X., Sun, Y., et al. (2020) · Nutrition · doi:10.1016/j.nut.2020.110755 · Cited by 5
Benaiges, D., Bisbe, M., Pedro‐Botet, J., de Vargas‐Machuca, A., Ramón, J. M., Pera, M., Villatoro, M., Fontané, L., Julià, H., Climent, E., et al. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9103193 · Cited by 5
“These results are in line with epidemiological studies that had reported a close relationship between weight loss and blood pressure reduction [23,24].”
ResultJiang, J., Wufuer, M., Simayi, A., Nijiati, M., Fan, M., Zhu, P., Chen, F., Shan, G., Xue, F., Tian, X., et al. (2013) · BMJ Open · doi:10.1136/bmjopen-2012-002279 · Cited by 5
Shrewsbury, V. A., Burrows, T. L., Ho, M. M., Jensen, M. E., Garnett, S. P., Stewart, L., Gow, M. L., Ells, L. J., Chai, L. K., Ashton, L., et al. (2018) · The JBI Database of Systematic Reviews and Implementation Reports · doi:10.11124/jbisrir-2017-003603 · Cited by 5
Filling the treatment gap in the weight management of overweight and obese patients
Gesundheit, N. (2012) · International Journal of Obesity Supplements · doi:10.1038/ijosup.2012.10 · Cited by 5
DeClercq, V., Defries, D. M., Hunt, R., Taylor, C. G., & Zahradka, P. C. (2011) · Wiley eBooks · doi:10.1002/9780470910016.ch4 · Cited by 5
Kwiringira, A., Migisha, R., Bulage, L., Kwesiga, B., Kadobera, D., Upenytho, G., Mbaka, P., Harris, J. R., Hayes, D., & Ario, A. R. (2024) · BMC Family Practice · doi:10.1186/s12875-024-02444-y · Cited by 4
“In addition, the program included several evidence-based components for improving blood pressure control, such as medication adherence [27], regular blood pressure monitoring [26], and encouraging lifestyle changes such as increased physical activity [28].”
BackgroundThe Effect of Behavioral Changes on the Treatment of Hypertension
Salman, L. A., & Cohen, D. L. (2021) · Current Hypertension Reports · doi:10.1007/s11906-021-01164-3 · Cited by 4
Chen, B., Hong, S., Wang, Y., Hu, Q., & Ma, D. (2024) · Nutrients · doi:10.3390/nu16193284 · Cited by 4
“Aucott et al. concluded in their systematic review that weight loss did not improve hypertension [42], and Gepner et al. found no alteration in blood pressure after an 18-month randomized controlled trial [43].”
BackgroundDelgado‐Floody, P., Navarrete, F. C., Poblete, A. O., & Jerez‐Mayorga, D. (2016) · Nutrición Hospitalaria · doi:10.20960/nh.16 · Cited by 4
Norfazilah, A., Julaina, M., & Nawi, A. M. (2015) · South African Family Practice · doi:10.1080/20786190.2015.1016719 · Cited by 4
Lifestyle behaviors and psychosocial outcomes among cancer survivors
Philip, E. J., Salamanca‐Balen, N., Lewis, B., & Merluzzi, T. V. (2018) · Psycho-Oncology · doi:10.1002/pon.4885 · Cited by 4
Weight loss and blood pressure normalization: the relevance of early interventions in hypertension
Cicero, A. F. G. (2010) · Hypertension Research · doi:10.1038/hr.2009.227 · Cited by 4
“Moreover, this relationship is not clear with respect to diastolic blood pressure”
BackgroundWITHDRAWN: The contemporary impact of body mass index on open aortic aneurysm repair
Bellamkonda, K. S., Scali, S. T., D’Oria, M., Columbo, J. A., Stableford, J. A., Goodney, P. P., Powell, R. J., Suckow, B. D., Jacobs, B. N., Cooper, M. A., et al. (2023) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2023.01.019 · Cited by 4
RetractedBattista, E. M. D., Bracken, R. M., Stephens, J. W., Rice, S., Thomas, M. C., Williams, S. P., Mellalieu, S. D., & the Prosiect Sir Gâr Group (2017) · Nutrition Bulletin · doi:10.1111/nbu.12292 · Cited by 5
Lu, X., Wang, J., Chen, S., Lv, L., & Yu, J.-M. (2025) · International Journal of Hypertension · doi:10.1155/ijhy/1165809 · Cited by 3
Multi-omic modelling of body mass index response to a dietary weight loss intervention
Yeo, E. N., Scadden, A. W., Caterer, Z., Sutton, K. J., Konigsberg, I. R., Cole, J. B., LITKOWSKI, E. M., Pan, Z., Lozupone, C., Ostendorf, D. M., et al. (2026) · Gut Microbes · doi:10.1080/19490976.2026.2696645 · Cited by 2
O’Brien, T., Rose, K. M., Focht, B. C., Kahlout, N. A., Jensen, T., Heareth, K., Nori, U. S., & Daloul, R. (2023) · Pilot and Feasibility Studies · doi:10.1186/s40814-023-01417-9 · Cited by 4
“Therefore, our study may have clinically meaningful results, as previous studies have found that a 3 kg (6.6 pounds) weight loss reduces BP [4, 43].”
ResultInfluentialAchieving control of resistant hypertension: Not just the number of blood pressure medications
Schmidt, K. M., Kelley, W., Tringali, S., & Huang, J. (2019) · World Journal of Hypertension · doi:10.5494/wjh.v9.i1.1 · Cited by 1
Metadata
- Authors
- Aucott, L., Rothnie, H., McIntyre, L., Thapa, M., Waweru, C., & Gray, D.
- Affiliations
- University of Aberdeen (GB)
- Venue
- Hypertension
- Published
- 2009-10
- Volume
- 54
- Issue
- 4
- Pages
- 756-762
- ISSN
- 0194-911X (ISSN-L)
- 1524-4563
- OpenAlex
- W2115856029
- Cited by
- 124
- References
- 31
- Citations by year
- 2026: 3 · 2025: 3 · 2024: 9 · 2023: 5 · 2022: 7 · 2021: 5 · 2020: 6 · 2019: 5 · 2018: 8 · 2017: 8 · 2016: 9 · 2015: 13 · 2014: 9 · 2013: 7 · 2012: 10
- FWCI
- 5.82
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Hypertension (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Health Sciences › Nursing › Nutrition and Dietetics › Sodium Intake and Health
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
- Keywords
- weight loss, lifestyle intervention, blood pressure, obesity, long-term weight change, systolic blood pressure, diastolic blood pressure, weight gain, hypertension prevention, obesity prevention
- MeSH terms
- Adolescent, Adult, Aged, Blood Pressure, Humans, Hypertension, Life Style, Middle Aged, Regression Analysis, Time Factors, Weight Loss, Body Mass Index, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
