The DOI matches its Crossref record; 90 of the 90 references it cites were found in a registry or an index.
Developmental and Early Life Origins of Cardiometabolic Risk Factors: Novel Findings and Implications
Open accessAbstract
The intent of this review is to critically consider the data that support the concept of programming and its implications. Birth weight and growth trajectories during childhood are associated with cardiometabolic disease in adult life. Both extremes, low and high birth weight coupled with postnatal growth increase the early presence of cardiometabolic risk factors and vascular imprinting, crucial elements of this framework. Data coming from epigenetics, proteomics, metabolomics, and microbiota added relevant information and contribute to better understanding of mechanisms as well as development of biomarkers helping to move forward to take actions. Research has reached a stage in which sufficiently robust data calls for new initiatives focused on early life. Prevention starting early in life is likely to have a very large impact on reducing disease incidence and its associated effects at the personal, economic, and social levels.
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In the citing paper
“Obesity, affected by both low and high birth weights, is a significant contributor to insulin resistance, dyslipidemia, and hyperinsulinemia, all of which are elements of metabolic syndrome.”
In the citing paper
“These factors substantially increase the risk of cardiovascular illnesses and lead to systemic metabolic disturbances [92].”
Citations
Cites
International Diabetes Federation 2017
Carracher, A. M., Marathe, P. H., & Close, K. L. (2018) · Journal of Diabetes · doi:10.1111/1753-0407.12644 · Cited by 13,379
Effect of In Utero and Early-Life Conditions on Adult Health and Disease
Gluckman, P. D., Hanson, M. A., Cooper, C., & Thornburg, K. L. (2008) · New England Journal of Medicine · doi:10.1056/nejmra0708473 · Cited by 3,898
WEIGHT IN INFANCY AND DEATH FROM ISCHAEMIC HEART DISEASE
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Barker, D. J., Osmond, C., Golding, J., Kuh, D., & Wadsworth, M. E. (1989) · BMJ · doi:10.1136/bmj.298.6673.564 · Cited by 2,415
Trajectories of growth among children who have coronary events as adults
Barker, D. J. P., Osmond, C., Forsén, T. J., Kajantie, E., & Eriksson, J. G. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa044160 · Cited by 1,517
Lurbe, E., Agabiti-Rosei, E., Cruickshank, J. K., Dominiczak, A., Erdine, S., Hirth, A., Invitti, C., Litwin, M., Mancia, G., Pall, D., et al. (2016) · Journal of Hypertension · doi:10.1097/hjh.0000000000001039 · Cited by 1,379
Self-citationGene Body Methylation Can Alter Gene Expression and Is a Therapeutic Target in Cancer
Yang, X., Han, H., De Carvalho, D. D., Lay, F. D., Jones, P. A., & Liang, G. (2014) · Cancer Cell · doi:10.1016/j.ccr.2014.07.028 · Cited by 1,199
Influence of Maternal Obesity on the Long-Term Health of Offspring
Godfrey, K. M., Reynolds, R. M., Prescott, S. L., Nyirenda, M., Jaddoe, V. W. V., Eriksson, J. G., & Broekman, B. F. P. (2017) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(16)30107-3 · Cited by 1,059
Human metabolic phenotype diversity and its association with diet and blood pressure
Holmes, E., Loo, R. L., Stamler, J., Bictash, M., Yap, I. K. S., Chan, Q., Ebbels, T., De Iorio, M., Brown, I. J., Veselkov, K. A., et al. (2008) · Nature · doi:10.1038/nature06882 · Cited by 1,054
Birth Weight and Risk of Type 2 Diabetes
Whincup, P. H., Kaye, S. J., Owen, C. G., Huxley, R., Cook, D. G., Anazawa, S., Barrett-Connor, E. L., Bhargava, S. K., Birgisdóttir, B. E., Carlsson, S., et al. (2008) · JAMA · doi:10.1001/jama.2008.886 · Cited by 949
Cited by
Sorted by citations
Obesity and Cardiometabolic Risk Factors: From Childhood to Adulthood
Drożdż, D., Pitti, J. Á., Wójcik, M., Borghi, C., Gabbianelli, R., Mazur, A., Herceg-Čavrak, V., López‐Valcárcel, B. G., Brzeziński, M., Lurbe, E., et al. (2021) · Nutrients · doi:10.3390/nu13114176 · Cited by 441
Self-citationSocial Determinants of Health and Disparities in Hypertension and Cardiovascular Diseases
Chaturvedi, A., Zhu, A., Gadela, N. V., Prabhakaran, D., & Jafar, T. H. (2023) · Hypertension · doi:10.1161/hypertensionaha.123.21354 · Cited by 258
Schutte, A. E., Jafar, T. H., Poulter, N. R., Damasceno, A., Khan, N. A., Nilsson, P. M., Alsaid, J., Neupane, D., Kario, K., Beheiry, H., et al. (2022) · Cardiovascular Research · doi:10.1093/cvr/cvac130 · Cited by 173
Polyploidy as a Fundamental Phenomenon in Evolution, Development, Adaptation and Diseases
Anatskaya, O. V., & Vinogradov, A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23073542 · Cited by 61
Alba‐Linares, J. J., Pérez, R. F., Tejedor, J. R., Bastante-Rodríguez, D., Ponce, F., Carbonell, N. G., Zafra, R. G., Fernández, A. F., Fraga, M. F., & Lurbe, E. (2023) · Cardiovascular Diabetology · doi:10.1186/s12933-023-01774-y · Cited by 67
Self-citation
Metadata
- Authors
- Lurbe, E., & Ingelfinger, J.
- Affiliations
- Universitat de València (ES)
- Harvard University (US)
- Venue
- Hypertension
- Published
- 2021-02
- Volume
- 77
- Issue
- 2
- Pages
- 308-318
- ISSN
- 0194-911X (ISSN-L)
- 1524-4563
- OpenAlex
- W3120874154
- Cited by
- 106
- References
- 90
- Citations by year
- 2026: 18 · 2025: 26 · 2024: 19 · 2023: 26 · 2022: 13 · 2021: 4
- FWCI
- 4.00
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- cc-by-nc
- Locations
- Hypertension (publishedVersion)
- PubMed (publishedVersion)
- Repository of Digital Objects for Teaching Research and Culture (University of Valencia) (submittedVersion, cc-by-nc)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Birth, Development, and Health
- Health Sciences › Medicine › Obstetrics and Gynecology › Pregnancy and preeclampsia studies
- Health Sciences › Medicine › Obstetrics and Gynecology › Gestational Diabetes Research and Management
- Keywords
- developmental origins of health and disease, cardiometabolic risk factors, birth weight, epigenetics, microbiota, metabolomics, proteomics, biomarkers
- MeSH terms
- Adverse Childhood Experiences, Adolescent, Adult, Aging, Birth Weight, Cardiovascular Diseases, Cardiovascular System, Child, Child, Preschool, Female, Forecasting, Gestational Age, Humans, Infant, Infant, Low Birth Weight, Infant, Newborn, Infant, Premature, Male, Metabolic Diseases, Middle Aged, Pregnancy, Prenatal Exposure Delayed Effects, Risk Factors, Proteomics, Epigenesis, Genetic, Metabolomics, Precision Medicine, Epigenomics, Microbiota
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