The DOI matches its Crossref record.
Small-Animal X-ray Dose from Micro-CT
Open accessAbstract
The use of micro-CT in small animals has increased in recent years. Although the radiation levels used for micro-CT are generally not lethal to the animal, they are high enough where changes in the immune response and other biological pathways may alter the experimental outcomes. Therefore, it is important to understand what the doses are for a specific imaging procedure. Monte Carlo simulation was used to evaluate the radiation dose to small animals (5–40 mm in diameter) as a result of X-ray exposure. Both monoenergetic (6–100 keV) and polyenergetic (15–100 kVp) X-ray sources were simulated under typical mouse imaging geometries. X-ray spectral measurements were performed on a mouse imaging X-ray system using a commercially available X-ray spectrometer, and spectra from high-energy systems were used as well. For a typical X-ray system with 1.0 mm of added Al at 40 kVp, the dose coefficients (dose to mouse per air kerma at isocenter) were 0.80, 0.63, 0.52, and 0.44 mGy/mGy for mouse diameters of 10, 20, 30, and 40 mm, respectively. A number of tables and figures are provided for dose estimation over a range of mouse imaging geometries.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Guidelines for the welfare and use of animals in cancer research
An ad hoc committee of the National Cancer Research Institute, Workman, P., Aboagye, E. O., Balkwill, F., Balmain, A., Bruder, G., Chaplin, D. J., Double, J. A., Everitt, J., Farningham, D. A. H., et al. (2010) · British Journal of Cancer · doi:10.1038/sj.bjc.6605642 · Cited by 1,442
Boone, J. M. (2007) · Medical Physics · doi:10.1118/1.2713240 · Cited by 417
Self-citationIn Vivo mouse imaging and spectroscopy in drug discovery
Beckmann, N., Kneuer, R., Gremlich, H., Karmouty‐Quintana, H., Blé, F., & Müller, M. (2007) · NMR in Biomedicine · doi:10.1002/nbm.1153 · Cited by 118
Microcomputed tomography colonography for polyp detection in an in vivo mouse tumor model
Pickhardt, P. J., Halberg, R. B., Taylor, A. J., Durkee, B. Y., Fine, J., Lee, F. T., & Weichert, J. P. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0409915102 · Cited by 43
Quantitative increase in T regulatory cells enhances bone remodeling in osteogenesis imperfecta
Kang, I.-H., Baliga, U. K., Chatterjee, S., Chakraborty, P., Choi, S., Buchweitz, N., Li, H., Wu, Y., Yao, H., Mehrotra, S., et al. (2022) · iScience · doi:10.1016/j.isci.2022.104818 · Cited by 28
Metadata
- Authors
- Boone, J. M., Velazquez, O., & Cherry, S. R.
- Venue
- Molecular Imaging
- Publisher
- SAGE Publications
- Published
- 2004-07-01
- Volume
- 3
- Issue
- 3
- Pages
- 149-158
- ISSN
- 1535-3508 (ISSN-L)
- 1536-0121
- OpenAlex
- W2121526802
- Cited by
- 201
- References
- 0
- FWCI
- 6.95
- Type
- journal article
- Language
- en
- Open access
- gold
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Small-Animal X-ray Dose from Micro-CT. https://app.cochat.ai/papers/10.1162/15353500200404118
- The paper
- Boone, J. M., Velazquez, O., & Cherry, S. R. (2004). Small-Animal X-ray Dose from Micro-CT. Molecular Imaging. https://doi.org/10.1162/15353500200404118
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
