The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.
Nutritional status and mortality in chronic obstructive pulmonary disease.
Abstract
The role of nutritional status in the prognosis of subjects with severe chronic obstructive pulmonary disease was studied in a cohort of Canadian men and women followed for 3 to 5 yr. A total of 348 subjects who were recruited for a study of negative pressure ventilation were evaluated for lung function and body weight, and a subset who entered hospital for the study (n=184) had baseline measures of diffusing capacity, maximal inspiratory and expiratory mouth pressure (PImax and PEmax), and blood gases. Predictors of survival were analyzed using Cox regression models. In the total cohort, low body mass index (BMI) and use of home oxygen were independently associated with reduced survival. In the hospitalized group, predictors of respiratory mortality were elevated PaCO2 and low BMI, PImax, and diffusing capacity. PaO2 (measured on oxygen therapy), FEV1, PEmax, age, smoking behavior, and gender were not associated with survival. The predictors of total mortality were similar, except that BMI was no longer significant. In conclusion, low body weight, a potentially modifiable factor, was associated with respiratory mortality, but whether it has a casual effect or is a marker of declining health can only be resolved through an intervention trial.
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Cites
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Effect of body weight and muscularity on human diaphragm muscle mass, thickness, and area
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Inspiratory Muscle Dysfunction and Chronic Hypercapnia in Chronic Obstructive Pulmonary Disease
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Cited by
Vestbo, J., Hurd, S. S., Agustí, A. G., Jones, P. W., Vogelmeier, C., Anzueto, A., Barnes, P. J., Fabbri, L. M., Martinez, F. J., Nishimura, M., et al. (2013) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201204-0596pp · Cited by 15,983
Weight Loss Is a Reversible Factor in the Prognosis of Chronic Obstructive Pulmonary Disease
SCHOLS, A. M. W. J., SLANGEN, J., VOLOVICS, L., & WOUTERS, E. F. M. (1998) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.157.6.9705017 · Cited by 1,085
International guidelines for the selection of lung transplant candidates
Maurer, J. R., Frost, A. E., Estenne, M., Higenbottam, T., & Glanville, A. R. (1998) · Transplantation · doi:10.1097/00007890-199810150-00033 · Cited by 562
International Guidelines for the Selection of Lung Transplant Candidates
(1998) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.158.1.15812 · Cited by 365
Orozco-Levi, M. (2003) · European Respiratory Journal · doi:10.1183/09031936.03.00004607 · Cited by 158
Metadata
- Authors
- Gray-Donald, K., Gibbons, L., Shapiro, S. H., Macklem, P. T., & Martin, J. G.
- Venue
- American Journal of Respiratory and Critical Care Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 1996-03
- Volume
- 153
- Issue
- 3
- Pages
- 961-966
- ISSN
- 1073-449X (ISSN-L)
- 1535-4970
- OpenAlex
- W2024879415
- Cited by
- 398
- References
- 18
- FWCI
- 11.35
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Nutritional status and mortality in chronic obstructive pulmonary disease. https://app.cochat.ai/papers/10.1164/ajrccm.153.3.8630580
- The paper
- Gray-Donald, K., Gibbons, L., Shapiro, S. H., Macklem, P. T., & Martin, J. G. (1996). Nutritional status and mortality in chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. https://doi.org/10.1164/ajrccm.153.3.8630580
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
