The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Passage of Intratracheally Instilled Ultrafine Particles from the Lung into the Systemic Circulation in Hamster
Abstract
The mechanisms of particulate pollution-related cardiovascular morbidity and mortality are not well understood. We studied the passage of radioactively labeled ultrafine particles after their intratracheal instillation. Hamsters received a single intratracheal instillation of 100 microg albumin nanocolloid particles (nominal diameter < or = 80 nm) labeled with 100 microCi technetium-99m and were killed after 5, 15, 30, and 60 min. In blood, radioactivity, expressed as percentage of total body radioactivity per gram blood, amounted to 2.88 +/- 0.80%, 1.30 +/- 0.17%, 1.52 +/- 0.46%, and 0.21 +/- 0.06% at 5, 15, 30, and 60 min, respectively. Thin-layer chromatography showed only one peak of radioactivity corresponding to unaltered (99m)Tc-albumin nanocolloid. In the liver, radioactivity, expressed as percentage of total radioactivity per organ, amounted to 0.10 +/- 0.07%, 0.23 +/- 0.06%, 1.24 +/- 0.27%, and 0.06 +/- 0.02% at 5, 15, 30, and 60 min, respectively. Lower values were observed in the heart, spleen, kidneys, and brain. Dose dependence was assessed at 30 min following instillation of 10 microg and 1 microg (99m)Tc-albumin per animal (n = 3 at each dose), and values of the same relative magnitudes as after instillation of 100 microg were obtained. We conclude that a significant fraction of (99m)Tc-albumin, taken as a model of ultrafine particles, rapidly diffuses from the lungs into the systemic circulation.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
An association between air pollution and mortality in six U.S. cities
Dockery, D. W., Pope, C. A., Xu, X., Spengler, J. D., Ware, J. H., Fay, M. E., Ferris, B. G., & Speizer, F. E. (1993) · New England Journal of Medicine · doi:10.1056/nejm199312093292401 · Cited by 8,018
Increased plasma viscosity during an air pollution episode: a link to mortality?
Peters, A., Döring, A., Wichmann, H.-E., & Koenig, W. (1997) · The Lancet · doi:10.1016/s0140-6736(97)01211-7 · Cited by 706
Air pollution and incidence of cardiac arrhythmia
Peters, A., Liu, E., Verrier, R. L., Schwartz, J., Gold, D. R., Mittleman, M., Baliff, J., Oh, J. A., Allen, G., Monahan, K., et al. (2000) · Epidemiology · doi:10.1097/00001648-200001000-00005 · Cited by 651
Heart rate variability associated with particulate air pollution
Pope, C. A., Verrier, R. L., Lovett, E. G., Larson, A. C., Raizenne, M. E., Kanner, R. E., Schwartz, J., Villegas, G. M., Gold, D. R., & Dockery, D. W. (1999) · American Heart Journal · doi:10.1016/s0002-8703(99)70014-1 · Cited by 595
Driscoll, K. E. (2000) · Toxicological Sciences · doi:10.1093/toxsci/55.1.24 · Cited by 578
Cited by
Nanomaterials and nanoparticles: Sources and toxicity
Buzea, C., Pacheco, I. I., & Robbie, K. (2007) · Biointerphases · doi:10.1116/1.2815690 · Cited by 3,789
Passage of inhaled particles into the blood circulation in humans
Nemmar, A., Hoet, P. H. M., Vanquickenborne, B., Dinsdale, D., Thomeer, M., Hoylaerts, M. F., Vanbilloen, H., Mortelmans, L., & Nemery, B. (2002) · Circulation · doi:10.1161/hc0402.104118 · Cited by 1,719
Self-citationDonaldson, K., Aitken, R., Tran, L., Stone, V., Duffin, R., Forrest, G., & Alexander, A. (2006) · Toxicological Sciences · doi:10.1093/toxsci/kfj130 · Cited by 1,167
Air Pollution and Dementia: A Systematic Review
Peters, R., Ee, N., Peters, J., Booth, A., Mudway, I., & Anstey, K. J. (2019) · Journal of Alzheimer’s Disease · doi:10.3233/jad-180631 · Cited by 548
Nanomaterials Versus Ambient Ultrafine Particles: An Opportunity to Exchange Toxicology Knowledge
Stone, V., Miller, M. R., Clift, M. J. D., Elder, A., Mills, N. L., Møller, P., Schins, R. P. F., Vogel, U., Kreyling, W. G., Alstrup Jensen, K., et al. (2017) · Environmental Health Perspectives · doi:10.1289/ehp424 · Cited by 370
Self-citationSemmler, M., Seitz, J., Erbe, F., Mayer, P., Heyder, J., Oberdörster, G., & Kreyling, W. G. (2004) · Inhalation Toxicology · doi:10.1080/08958370490439650 · Cited by 340
Brown, D. M., Kinloch, I. A., Bangert, U., Windle, A. H., Walter, D. M., Walker, G. S., Scotchford, C. A., Donaldson, K., & Stone, V. (2007) · Carbon · doi:10.1016/j.carbon.2007.05.011 · Cited by 271
Dailey, L. A., Jekel, N., Fink, L., Gessler, T., Schmehl, T., Wittmar, M., Kissel, T., & Seeger, W. (2006) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2006.01.016 · Cited by 220
Gómez-Roig, M. D., Pascal, R., Cahuana, M. J., García-Algar, O., Sebastiani, G., Andreu-Fernández, V., Martínez, L., Rodríguez, G., Iglesia, I., Ortiz-Arrabal, O., et al. (2021) · Fetal Diagnosis and Therapy · doi:10.1159/000514884 · Cited by 207
Inflammatory markers and particulate air pollution: characterizing the pathway to disease
Zeka, A., Sullivan, J. R., Vokonas, P. S., Sparrow, D., & Schwartz, J. (2006) · International Journal of Epidemiology · doi:10.1093/ije/dyl132 · Cited by 205
A review of epidemiological studies on neuropsychological effects of air pollution
Guxens, M., & Sunyer, J. (2012) · Swiss Medical Weekly · doi:10.57187/smw.2012.13322 · Cited by 172
Kinetics of gold nanoparticles in the human placenta
Myllynen, P. K., Loughran, M. J., Howard, C. V., Sormunen, R., Walsh, A. A., & Vähäkangas, K. H. (2008) · Reproductive Toxicology · doi:10.1016/j.reprotox.2008.06.008 · Cited by 158
Air Pollution and Alzheimer’s Disease: A Systematic Review and Meta-Analysis
Fu, P., & Yung, K. K. L. (2020) · Journal of Alzheimer's Disease · doi:10.3233/jad-200483 · Cited by 146
Chen, J., Tan, M., Nemmar, A., Song, W., Dong, M., Zhang, G., & Li, Y. (2006) · Toxicology · doi:10.1016/j.tox.2006.02.016 · Cited by 132
Self-citationWang, B., Feng, W., Zhu, M., Wang, Y., Wang, M., Gu, Y., Ouyang, H., Wang, H., Li, M., Zhao, Y., et al. (2009) · Journal of Nanoparticle Research · doi:10.1007/s11051-008-9452-6 · Cited by 119
Nakane, H. (2012) · Environmental Health and Preventive Medicine · doi:10.1007/s12199-011-0252-8 · Cited by 101
Is air pollution associated with increased risk of cognitive decline? A systematic review
Peters, R., Peters, J., Booth, A., & Mudway, I. (2015) · Age and Ageing · doi:10.1093/ageing/afv087 · Cited by 65
MOSTOFI, R., WANG, B., HAGHIGHAT, F., BAHLOUL, A., & JAIME, L. (2010) · Industrial Health · doi:10.2486/indhealth.48.296 · Cited by 58
Kulas, J. A., Hettwer, J. V., Sohrabi, M., Melvin, J. E., Manocha, G. D., Puig, K. L., Gorr, M. W., Tanwar, V., McDonald, M. P., Wold, L. E., et al. (2018) · Environmental Pollution · doi:10.1016/j.envpol.2018.05.047 · Cited by 50
Zanini, M. J., Domínguez, C., Fernández-Oliva, T., Sánchez, O., Toda, M. T., Foraster, M., Dadvand, P., & Llurba, E. (2020) · Current Hypertension Reports · doi:10.1007/s11906-020-01088-4 · Cited by 29
Liu, Y., Li, Y., Xu, H., Zhao, X., Zhu, Y., Zhao, B., Yao, Q., Duan, H., Guo, C., & Li, Y. (2023) · Environmental Research · doi:10.1016/j.envres.2023.115373 · Cited by 21
Metadata
- Authors
- NEMMAR, A., VANBILLOEN, H., HOYLAERTS, M. F., HOET, P. H. M., VERBRUGGEN, A., & NEMERY, B.
- Venue
- American Journal of Respiratory and Critical Care Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 2001-11-01
- Volume
- 164
- Issue
- 9
- Pages
- 1665-1668
- ISSN
- 1073-449X (ISSN-L)
- 1535-4970
- OpenAlex
- W2152148584
- Cited by
- 643
- References
- 5
- FWCI
- 10.64
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
