Pressure Support Reduces Inspiratory Effort and Dyspnea during Exercise in Chronic Airflow Obstruction
Abstract
Exercise training has been of limited success in patients with severe chronic airflow obstruction (CAO), in part because of the reduced ventilatory capacity and excessive dyspnea experienced. Pressure support (PS) is a new form of mechanical ventilation which can effectively assist ventilation when applied noninvasively to patients in acute respiratory failure. It was hypothesized that PS might also be used to improve exercise performance, and ultimately physical conditioning, in ambulatory patients with CAO undergoing exercise training. To begin to address this concept, the objectives of the present study were (1) to examine the feasibility of providing PS to exercising patients with CAO and (2) to determine its effects on breathing pattern, inspiratory effort, and dyspnea. Flow and volume, mouth, esophageal, and gastric pressure were measured in seven patients with severe CAO (mean FEV1 = 0.75 +/- SEM 0.09 L) performing constant workload bicycle exercise (33 +/- 6 watts) during control conditions and with the application of PS (approximately 10 cm H2O). PS increased minute ventilation as a result of changes in both tidal volume and respiratory rate. This occurred despite marked reductions in inspiratory effort, as indicated by the pressure-time integrals of esophageal (68 +/- 5% control, p < 0.0005) and transdiaphragmatic pressure (52 +/- 8% control, p < 0.0005). Using a 5-point bidirectional scale to assess changes in dyspnea, breathlessness improved significantly with the addition of PS (2.3 +/- 0.6, p < 0.05) and worsened to a similar degree when it was removed (2.1 +/- 0.5, p < 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The effects of ventilatory support on dyspnea are probably mostly related to unloading of the inspiratory muscles during exercise.
“The effects of these interventions on dyspnea are probably mostly related to unloading of the inspiratory muscles during exercise.155,157–160”
From Pathogenesis of hyperinflation in chronic obstructive pulmonary disease (2014) · cites this paper as [159]
Cites
Still being checked.
Cited by
Sorted by citations
Spruit, M. A., Singh, S. J., Garvey, C., ZuWallack, R., Nici, L., Rochester, C., Hill, K., Holland, A. E., Lareau, S. C., Man, W. D.-C., et al. (2013) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201309-1634st · Cited by 3,938 · see citing works
Self-citationAmerican Thoracic Society/European Respiratory Society statement on pulmonary rehabilitation
Nici, L., Donner, C., Wouters, E., Zuwallack, R., Ambrosino, N., Bourbeau, J., Carone, M., Celli, B., Engelen, M., Fahy, B., et al. (2006) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200508-1211st · Cited by 1,966 · see citing works
Self-citationDyspnea Mechanisms, Assessment and Management: A Consensus Statement
Editorial, A. (2005) · PULMONOLOGIYA · doi:10.18093/0869-0189-2005-0-2-9-36 · Cited by 859 · see citing works
ERS statement on respiratory muscle testing at rest and during exercise
Laveneziana, P., Albuquerque, A., Aliverti, A., Babb, T., Barreiro, E., Dres, M., Dubé, B., Fauroux, B., Gea, J., Guenette, J., et al. (2019) · European Respiratory Journal · doi:10.1183/13993003.01214-2018 · Cited by 743 · see citing works
Pulmonary Rehabilitation in Chronic Obstructive Pulmonary Disease
Troosters, T., Casaburi, R. H., Gosselink, R., & Decramer, M. (2005) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200408-1109so · Cited by 644 · see citing works
Pathophysiology of dyspnea in chronic obstructive pulmonary disease: a roundtable.
O'Donnell, D., Banzett, R., Carrieri-Kohlman, V., Casaburi, R., Davenport, P., Gandevia, S., Gelb, A., Mahler, D., & Webb, K. (2007) · Proceedings of the American Thoracic Society · doi:10.1513/pats.200611-159cc · Cited by 389 · see citing works
Common Mechanisms of Dyspnea in Chronic Interstitial and Obstructive Lung Disorders
Faisal, A., Alghamdi, B. J., Ciavaglia, C. E., Elbehairy, A. F., Webb, K. A., Ora, J., Neder, J. A., & O’Donnell, D. E. (2015) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201504-0841oc · Cited by 268 · see citing works
Rennard, S. I., Anderson, W. H., ZuWallack, R., Broughton, J. O., Bailey, W. C., Friedman, M. B., Wisniewski, M., & RICKARD, K. A. (2001) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.163.5.9903053 · Cited by 259 · see citing works
Mechanisms of activity-related dyspnea in pulmonary diseases
O’Donnell, D. E., Ora, J., Webb, K. A., Laveneziana, P., & Jensen, D. (2009) · Respiratory Physiology & Neurobiology · doi:10.1016/j.resp.2009.01.010 · Cited by 235 · see citing works
Pathogenesis of hyperinflation in chronic obstructive pulmonary disease
Saey, Gagnon, P., Guenette, J., Langer, D., Laviolette, L., Mainguy, V., Maltais, F., & Ribeiro, F. (2014) · International Journal of Chronic Obstructive Pulmonary Disease · doi:10.2147/copd.s38934 · Cited by 180 · see citing works
Self-citationHawkins, P. (2002) · Thorax · doi:10.1136/thorax.57.10.853 · Cited by 157 · see citing works
Mechanisms, assessment and therapeutic implications of lung hyperinflation in COPD
Rossi, A., Айсанов, З. Р., Avdeev, S. N., Maria, G. D., Donner, C. F., Alonso, J. L. I., Roche, N., Similowski, T., Watz, H., Worth, H., et al. (2015) · Respiratory Medicine · doi:10.1016/j.rmed.2015.03.010 · Cited by 151 · see citing works
Pulmonary hyperinflation a clinical overview
Gibson, G. J. (1996) · European Respiratory Journal · doi:10.1183/09031936.96.09122640 · Cited by 138 · see citing works
Kyroussis, D., Polkey, M. I., Hamnegard, C., MILLS, G. H., Green, M., & Moxham, J. (2000) · European Respiratory Journal · doi:10.1034/j.1399-3003.2000.15d05.x · Cited by 128 · see citing works
Training with inspiratory pressure support in patients with severe COPD
Hul, A. J. V. ‘., Gosselink, R., Hollander, P., Postmus, P. E., & Kwakkel, G. (2005) · European Respiratory Journal · doi:10.1183/09031936.06.00036505 · Cited by 126 · see citing works
Bianchi, L. N. C., Foglio, K., Pagani, M., Vitacca, M., Rossi, A., & Ambrosino, N. (1998) · European Respiratory Journal · doi:10.1183/09031936.98.11020422 · Cited by 117 · see citing works
Bianchi, L. N. C., Foglio, K., Porta, R., Baiardi, P., Vitacca, M., & Ambrosino, N. (2002) · Respiratory Medicine · doi:10.1053/rmed.2001.1287 · Cited by 112 · see citing works
Noninvasive ventilation during walking in patients with severe COPD: a randomised cross-over trial
Dreher, M., Storre, J. H., & Windisch, W. (2007) · European Respiratory Journal · doi:10.1183/09031936.00075806 · Cited by 112 · see citing works
New strategies to improve exercise tolerance in chronic obstructive pulmonary disease
Ambrosino, N., & Strambi, S. (2004) · European Respiratory Journal · doi:10.1183/09031936.04.00002904 · Cited by 164 · see citing works
Johnson, J. E., Gavin, D. J., & Adams-Dramiga, S. (2002) · CHEST Journal · doi:10.1378/chest.122.2.464 · Cited by 108 · see citing works
van ???t Hul, A., Kwakkel, G., & Gosselink, R. (2002) · Journal of Cardiopulmonary Rehabilitation · doi:10.1097/00008483-200207000-00013 · Cited by 88 · see citing works
Langer, D., Ciavaglia, C. E., Neder, J., Webb, K., & O'Donnell, D. (2014) · Expert Review of Respiratory Medicine · doi:10.1586/17476348.2014.949676 · Cited by 80 · see citing works
Acute effects of inspiratory pressure support during exercise in patients with COPD
van 't Hul, A., Gosselink, R., Hollander, P., Postmus, P., & Kwakkel, G. (2004) · European Respiratory Journal · doi:10.1183/09031936.03.00016903 · Cited by 79 · see citing works
Menadue, C., Piper, A. J., Hul, A. J. V. ‘., & WONG, K. K. H. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007714.pub2 · Cited by 75 · see citing works
Diaphragm Performance During Maximal Voluntary Ventilation in Chronic Obstructive Pulmonary Disease
Polkey, M. I., Kyroussis, D., Hamnegärd, C. H., MILLS, G. H., Hughes, P. D., Green, M., & Moxham, J. (1997) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.155.2.9032207 · Cited by 73 · see citing works
Hyperinflation and its management in COPD
Puente-Maestu, L., & Stringer, W. (2006) · International Journal of COPD · doi:10.2147/copd.2006.1.4.381 · Cited by 81 · see citing works
Exercise Training Improves Outcomes of a Dyspnea Self-management Program
Stulbarg, M. S., Carrieri‐Kohlman, V., Demir‐Deviren, S., Nguyen, H. Q., Adams, L., Tsang, A. H., Duda, J., Gold, W. M., & Paul, S. M. (2002) · Journal of Cardiopulmonary Rehabilitation · doi:10.1097/00008483-200203000-00010 · Cited by 69 · see citing works
Navalesi, P., Hernandez, P., Wongsa, A., Laporta, D., Goldberg, P., & Gottfried, S. B. (1996) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.154.5.8912744 · Cited by 73 · see citing works
Self-citationCharususin, N., Dacha, S., Gosselink, R., Decramer, M., von Leupoldt, A., Reijnders, T., Louvaris, Z., & Langer, D. (2017) · Expert Review of Respiratory Medicine · doi:10.1080/17476348.2018.1398084 · Cited by 73 · see citing works
Polkey, M. I., Kyroussis, D., Mills, G. H., Hamnegard, C. H., Keilty, S. E., Green, M., & Moxham, J. (1996) · American journal of respiratory and critical care medicine · doi:10.1164/ajrccm.154.4.8887619 · Cited by 71 · see citing works
Proportional Assist Ventilation and Exercise Tolerance in Subjects With COPD
Dolmage, T. E., & Goldstein, R. S. (1997) · CHEST Journal · doi:10.1378/chest.111.4.948 · Cited by 71 · see citing works
Hernandez, P., Maltais, F., Gursahaney, A., Leblanc, P., & Gottfried, S. B. (2001) · Journal of Cardiopulmonary Rehabilitation · doi:10.1097/00008483-200105000-00003 · Cited by 63 · see citing works
Self-citationRehabilitation and acute exacerbations
Burtin, C., Decramer, M., Gosselink, R., Janssens, W., & Troosters, T. (2011) · European Respiratory Journal · doi:10.1183/09031936.00079111 · Cited by 63 · see citing works
Exercise and muscle dysfunction in COPD: implications for pulmonary rehabilitation.
Man, W., Kemp, P. R., Moxham, J., & Polkey, M. (2009) · Clinical science · doi:10.1042/cs20080660 · Cited by 62 · see citing works
Strategies of muscle training in very severe COPD patients: Figure 1–
Vogiatzis, I. (2011) · European Respiratory Journal · doi:10.1183/09031936.00075011 · Cited by 52 · see citing works
Adjuncts to Physical Training of Patients With Severe COPD: Oxygen or Noninvasive Ventilation?
Borghi‐Silva, A., Mendes, R. G., Toledo, A., Sampaio, L. M. M., da Silva, T. P., Kunikoshita, L. N., de Souza, H. C. D., Salvini, T. F., & Costa, D. (2010) · Respiratory Care · doi:10.4187/respcare.10550885 · Cited by 50 · see citing works
Marco, F. D., Sotgiu, G., Santus, P., O’Donnell, D. E., Beeh, K. M., Dore, S., Roggi, M. A., Giuliani, L., Blasi, F., & Centanni, S. (2018) · Respiratory Research · doi:10.1186/s12931-018-0721-3 · Cited by 48 · see citing works
Dreher, M., Doncheva, E., Schwoerer, A., Walterspacher, S., Sonntag, F., Kabitz, H., & Windisch, W. (2008) · Respiration · doi:10.1159/000187717 · Cited by 47 · see citing works
Aboussouan, L. S. (2009) · Chronic Respiratory Disease · doi:10.1177/1479972309345927 · Cited by 46 · see citing works
Functional differences in bi-level pressure preset ventilators
Highcock, M., Shneerson, J. M., & Smith, I. E. (2001) · European Respiratory Journal · doi:10.1183/09031936.01.17202680 · Cited by 44 · see citing works
Physiologic effects of an ambulatory ventilation system in chronic obstructive pulmonary disease.
Porszasz, J., Cao, R., Morishige, R., van Eykern, L. V., Stenzler, A., & Casaburi, R. (2013) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201210-1773oc · Cited by 40 · see citing works
Response of the respiratory muscles to rehabilitation in COPD.
Decramer, M. (2009) · Journal of applied physiology · doi:10.1152/japplphysiol.91459.2008 · Cited by 52 · see citing works
Increased respiratory neural drive and work of breathing in exercise-induced laryngeal obstruction
Walsted, E. S., Faisal, A., Jolley, C. J., Swanton, L. L., Pavitt, M. J., Luo, Y., Backer, V., Polkey, M. I., & Hull, J. H. (2017) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00691.2017 · Cited by 42 · see citing works
Revill, S. M., Singh, S. J., & Morgan, M. D. L. (2000) · Respiratory Medicine · doi:10.1053/rmed.2000.0824 · Cited by 42 · see citing works
Pulmonary rehabilitation in chronic obstructive pulmonary disease
Derom, E., Marchand, É., & Troosters, T. (2007) · Annales de Réadaptation et de Médecine Physique · doi:10.1016/j.annrmp.2007.04.022 · Cited by 40 · see citing works
Grazzini, M., Stendardi, L., Gigliotti, F., & Scano, G. (2005) · Respiratory Medicine · doi:10.1016/j.rmed.2005.03.005 · Cited by 39 · see citing works
Ventilatory Support During Exercise in Patients With Pulmonary Tuberculosis Sequelae
Tsuboi, T., Ohi, M., Chin, K., Hirata, H., Otsuka, N., Kita, H., & Kuno, K. (1997) · CHEST Journal · doi:10.1378/chest.112.4.1000 · Cited by 37 · see citing works
Respiratory muscle energetics during exercise in healthy subjects and patients with COPD
Scano, G., Grazzini, M., Stendardi, L., & Gigliotti, F. (2006) · Respiratory Medicine · doi:10.1016/j.rmed.2006.02.030 · Cited by 36 · see citing works
Vivodtzev, I., Tamisier, R., Croteau, M., Borel, J., Grangier, A., Wuyam, B., Levy, P. A., Minville, C., Sériès, F., Maltais, F., et al. (2018) · Thorax · doi:10.1136/thoraxjnl-2017-211152 · Cited by 33 · see citing works
Self-citationNon invasive ventilation as an additional tool for exercise training
Ambrosino, N., & Cigni, P. (2015) · Multidisciplinary Respiratory Medicine · doi:10.1186/s40248-015-0008-1 · Cited by 29 · see citing works
Menadue, C., Alison, J. A., Piper, A. J., Flunt, D., & Ellis, E. R. (2008) · Respirology · doi:10.1111/j.1440-1843.2008.01449.x · Cited by 29 · see citing works
Potential Role of Patent Foramen Ovale in Exacerbating Hypoxemia in Chronic Pulmonary Disease
Layoun, M. E., Aboulhosn, J., & Tobis, J. M. (2017) · Texas Heart Institute Journal · doi:10.14503/thij-16-6027 · Cited by 29 · see citing works
Developing concepts in the pulmonary rehabilitation of COPD
Ambrosino, N., Casaburi, R. H., Ford, G. T., Goldstein, R. S., Morgan, M. D. L., Rudolf, M., Singh, S. J., & Wijkstra, P. J. (2008) · Respiratory Medicine · doi:10.1016/s0954-6111(08)70004-0 · Cited by 27 · see citing works
Exercise dyspnea in patients with COPD.
Stendardi, L., Binazzi, B., & Scano, G. (2007) · PubMed Central · Cited by 26 · see citing works
Oliveira, C. C., Carrascosa, C. R., Borghi‐Silva, A., Berton, D. C., Queiroga, F., Ferreira, E. V. M., Nery, L. E., & Neder, J. A. (2010) · European Journal of Applied Physiology · doi:10.1007/s00421-010-1408-8 · Cited by 26 · see citing works
Nicolini, A., Merliak, F., & BARLASCINI, C. O. (2013) · Multidisciplinary Respiratory Medicine · doi:10.1186/2049-6958-8-19 · Cited by 26 · see citing works
The Use of Non-invasive Ventilation during Exercise Training in COPD Patients
Ambrosino, N., & Xie, L. (2017) · COPD Journal of Chronic Obstructive Pulmonary Disease · doi:10.1080/15412555.2017.1298582 · Cited by 26 · see citing works
Increased ventilation with NiIPPV does not necessarily improve exercise capacity in COPD
Highcock, M., Shneerson, J. M., & Smith, I. E. (2003) · European Respiratory Journal · doi:10.1183/09031936.03.00292203 · Cited by 26 · see citing works
Vrijsen, B., Chatwin, M., Contal, O., Derom, E., Janssens, J.-P., Kampelmacher, M. J., Muir, J., Pinto, S., Rabec, C. A., Ramsay, M., et al. (2015) · Respiratory Care · doi:10.4187/respcare.03796 · Cited by 24 · see citing works
Dubé, B., Vermeulen, F., & Laveneziana, P. (2016) · Archivos de Bronconeumología · doi:10.1016/j.arbres.2016.09.005 · Cited by 24 · see citing works
Pathophysiology of Dyspnea in Chronic Obstructive Pulmonary Disease
O’Donnell, D. E., Banzett, R. B., Carrieri‐Kohlman, V., Casaburi, R. H., Davenport, P. W., Gandevia, S. C., Gelb, A. F., Mahler, D. A., & Webb, K. A. (2012) · Proceedings of the American Thoracic Society · Cited by 24 · see citing works
Mechanisms of non-pharmacologic adjunct therapies used during exercise in COPD
Moga, A. M., de Marchie, M., Saey, D., & Spahija, J. (2012) · Respiratory Medicine · doi:10.1016/j.rmed.2012.01.006 · Cited by 23 · see citing works
Vitacca, M., Bianchi, L. N. C., Sarva, M. C., Paneroni, M., & Balbi, B. (2006) · Intensive Care Medicine · doi:10.1007/s00134-006-0216-4 · Cited by 23 · see citing works
Poggi, R., Appendini, L., Polese, G., Colombo, R., Donner, C. F., & Rossi, A. (2005) · Respiratory Medicine · doi:10.1016/j.rmed.2005.10.007 · Cited by 23 · see citing works
GIGLIOTTI, F., ROMAGNOLI, I., & SCANO, G. (2003) · Respiratory Medicine · doi:10.1053/rmed.2003.1434 · Cited by 33 · see citing works
Contrasting pressure-support ventilation and helium–oxygen during exercise in severe COPD
Hussain, O., Collins, E. G., Adiguzel, N., Langbein, W. E., Tobin, M. J., & Laghi, F. (2011) · Respiratory Medicine · doi:10.1016/j.rmed.2010.08.008 · Cited by 22 · see citing works
Dennis, C. J., Menadue, C., Schneeberger, T., Leitl, D., Schoenheit‐Kenn, U., Hoyos, C. M., Harmer, A. R., Barnes, D. J., Koczulla, A. R., Kenn, K., et al. (2021) · CHEST Journal · doi:10.1016/j.chest.2021.06.050 · Cited by 21 · see citing works
Shaikh, Z. F., Kelly, J. L., Shrikrishna, D., Villa, M. D., Mullen, M. J., Hopkinson, N. S., Morrell, M. J., & Polkey, M. I. (2014) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201309-1618oc · Cited by 21 · see citing works
Measurement of diaphragm loading during pressure support ventilation
Fauroux, B., Hart, N., Luo, Y. M., MacNeill, S., Moxham, J., Lofaso, F., & Polkey, M. I. (2003) · Intensive Care Medicine · doi:10.1007/s00134-003-1941-6 · Cited by 21 · see citing works
Non-invasive ventilation (NIV) as an aid to rehabilitation in acute respiratory disease
Dyer, F., Flude, L., Bazari, F., Jolley, C. J., Englebretsen, C., Lai, D., Polkey, M. I., & Hopkinson, N. S. (2011) · BMC Pulmonary Medicine · doi:10.1186/1471-2466-11-58 · Cited by 20 · see citing works
Hoo, G. W. S. (2003) · The Journal of Rehabilitation Research and Development · doi:10.1682/jrrd.2003.10.0081 · Cited by 21 · see citing works
Bilevel ventilation during exercise in acute on chronic respiratory failure: A preliminary study
Menadue, C., Alison, J. A., Piper, A. J., Flunt, D., & Ellis, E. R. (2009) · Respiratory Medicine · doi:10.1016/j.rmed.2009.08.015 · Cited by 19 · see citing works
Highcock, M., Smith, I. E., & Shneerson, J. M. (2002) · CHEST Journal · doi:10.1378/chest.121.5.1555 · Cited by 19 · see citing works
Strategies to Enhance the Benefits of Exercise Training in the Respiratory Patient
Hill, K., & Holland, A. E. (2014) · Clinics in Chest Medicine · doi:10.1016/j.ccm.2014.02.003 · Cited by 16 · see citing works
Jensen, D., Schaeffer, M. R., & Guenette, J. A. (2018) · Current Opinion in Supportive and Palliative Care · doi:10.1097/spc.0000000000000377 · Cited by 16 · see citing works
Exertional Dyspnoea in Chronic Respiratory Diseases: From Physiology to Clinical Application
Dubé, B., Vermeulen, F., & Laveneziana, P. (2016) · Archivos de Bronconeumología · doi:10.1016/j.arbr.2016.11.003 · Cited by 16 · see citing works
Allan, P., Thomas, K. V., Ward, M. R., Harris, A., Naworol, G. A., & Ward, J. (2009) · Respiratory care · doi:10.4187/respcare.09541175 · Cited by 15 · see citing works
New Approaches in Pulmonary Rehabilitation
Ambrosino, N., Palmiero, G., & Strambi, S.-K. (2007) · Clinics in Chest Medicine · doi:10.1016/j.ccm.2007.06.001 · Cited by 14 · see citing works
High- and low-level pressure support during walking in people with severe kyphoscoliosis
Menadue, C., Alison, J. A., Piper, A. J., WONG, K. K. H., Hollier, C. A., & Ellis, E. R. (2010) · European Respiratory Journal · doi:10.1183/09031936.00115009 · Cited by 14 · see citing works
Noninvasive Ventilation in Chronic Obstructive Pulmonary Disease
Hill, N. S. (2000) · Clinics in Chest Medicine · doi:10.1016/s0272-5231(05)70184-2 · Cited by 14 · see citing works
Update: Non-Invasive Positive Pressure Ventilation in Chronic Respiratory Failure Due to COPD
Altıntaş, N. (2015) · COPD Journal of Chronic Obstructive Pulmonary Disease · doi:10.3109/15412555.2015.1043520 · Cited by 13 · see citing works
Pessoa, I. M. B. S., Costa, D., Velloso, M., Mancuzo, E. V., Reis, M. A. S., & Parreira, V. F. (2012) · Brazilian Journal of Physical Therapy · doi:10.1590/s1413-35552012005000007 · Cited by 13 · see citing works
Bittencourt, H. S., da Cruz, C. G., David, B. C., Rodrigues, E. D. S., Abade, C. M., Aras, R., Carvalho, V. O., dos Reis, F. J. F. B., & Neto, M. G. (2017) · Clinical Rehabilitation · doi:10.1177/0269215517704269 · Cited by 13 · see citing works
Jensen, D., Pattinson, K. T. S., & Jolley, C. J. (2016) · European Respiratory Society eBooks · doi:10.1183/2312508x.10011715 · Cited by 11 · see citing works
NIV Is not Adequate for High Intensity Endurance Exercise in COPD
Bonnevie, T., Gravier, F., Fresnel, E., Kerfourn, A., Médrinal, C., Prieur, G., Combret, Y., Muir, J., Cuvelier, A., Debeaumont, D., et al. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9041054 · Cited by 11 · see citing works
Wang, K., Liang, Z., Wang, X., Li, Y., Lu, Y.-R., Liu, J., Li, J., Xu, L., Chen, G., Chang, P., et al. (2020) · Journal of Thoracic Disease · doi:10.21037/jtd.2019.12.120 · Cited by 10 · see citing works
Hamnegard, C., Polkey, M. I., Kyroussis, D., MILLS, G. H., Green, M., Bake, B., & Moxham, J. (1998) · European Respiratory Journal · doi:10.1183/09031936.98.12030693 · Cited by 10 · see citing works
Menadue, C., Piper, A. J., Hul, A. J. V. ‘., & WONG, K. K. H. (2009) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007714 · Cited by 9 · see citing works
Ou, Y., Lin, Z., Wu, W., Luo, Q., & Chen, R. (2016) · Respiratory Medicine · doi:10.1016/j.rmed.2016.11.006 · Cited by 8 · see citing works
Chen, Y.-H., Lin, H., Hsiao, H.-F., Huang, C.-T., Kao, K., Li, L., Huang, C.-C., & Tsai, Y. (2014) · Journal of the Formosan Medical Association · doi:10.1016/j.jfma.2014.09.002 · Cited by 8 · see citing works
Effects of negative pressure assisted ventilation on dyspnoeic sensation and breathing pattern
Nishino, T., Isono, S., & Ide, T. (1998) · European Respiratory Journal · doi:10.1183/09031936.98.12061278 · Cited by 8 · see citing works
Moga, A. M., de Marchie, M., Saey, D., & Spahija, J. (2014) · COPD Journal of Chronic Obstructive Pulmonary Disease · doi:10.3109/15412555.2014.908830 · Cited by 7 · see citing works
Labeix, P., Berger, M., Court‐Fortune, I., Féasson, L., Vergès, S., & Costes, F. (2019) · International Journal of COPD · doi:10.2147/copd.s216347 · Cited by 6 · see citing works
Nicolini, A., Merliak, F., & BARLASCINI, C. O. (2013) · Multidisciplinary Respiratory Medicine · doi:10.4081/mrm.2013.493 · Cited by 6 · see citing works
Exercise Prescription for Patients With Chronic Lung Disease
Fierro-Carrion, G. A., & Mahler, D. A. (2002) · Clinical Pulmonary Medicine · doi:10.1097/00045413-200201000-00001 · Cited by 6 · see citing works
van der Vaart, van der Vaart, Grevink, Roemer, ten Hacken, N. H. T., & Postma, D. S. (2011) · International Journal of COPD · doi:10.2147/copd.s17482 · Cited by 5 · see citing works
Non invasive ventilation as an additional tool for exercise training
Ambrosino, N., & Cigni, P. (2015) · Multidisciplinary Respiratory Medicine · doi:10.4081/mrm.2015.286 · Cited by 4 · see citing works
ZuWallack, R. (2007) · doi:10.1002/9780470755976.ch50 · Cited by 4 · see citing works
Nici, L. L., Donner, C. F., Wouters, E. F. �., ZuWallack, R., Ambrosino, N., Bourbeau, J., Carone, M., Celli, B. R., ENGELEN, M. P. K. J., Fahy, B. F., et al. (2006) · Cited by 3 · see citing works
Self-citationEffects of Pressure Support Ventilation May Be Lost at High Exercise Intensities in People with COPD
Anekwe, D. E., de Marchie, M., & Spahija, J. (2017) · COPD Journal of Chronic Obstructive Pulmonary Disease · doi:10.1080/15412555.2017.1304533 · Cited by 3 · see citing works
- Authors
- Maltais, F., Reissmann, H., & Gottfried, S. B.
- Affiliations
- Montreal General Hospital (CA)
- ORCID
- Maltais, François
- Venue
- American Journal of Respiratory and Critical Care Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 1995-04-01
- Volume
- 151
- Issue
- 4
- Pages
- 1027-1033
- ISSN
- 1073-449X (ISSN-L)
- 1535-4970
- OpenAlex
- W2059358834
- Cited by
- 132
- References
- 0
- Citations by year
- 2024: 2 · 2022: 1 · 2021: 3 · 2020: 5 · 2019: 3 · 2018: 3 · 2017: 6 · 2016: 5 · 2015: 9 · 2014: 8 · 2013: 6 · 2012: 5
- FWCI
- 3.95
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Respiratory and Critical Care Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Respiratory Support and Mechanisms
- Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Keywords
- pressure support ventilation, chronic airflow obstruction, exercise training, inspiratory effort, dyspnea, esophageal pressure, transdiaphragmatic pressure, minute ventilation, breathing pattern, exercise performance, non-invasive ventilation
- MeSH terms
- Adult, Aged, Dyspnea, Female, Humans, Lung Diseases, Obstructive, Male, Middle Aged, Respiration, Artificial, Respiratory Muscles, Exercise, Respiratory Mechanics
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
