Cited by 509Respiratory Support and MechanismsNeonatal Respiratory Health ResearchNosocomial Infections in ICU

The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.

Tidal Volume Reduction in Patients with Acute Lung Injury When Plateau Pressures Are Not High

Open access

Hager, David N., Krishnan, Jerry A., Hayden, Douglas L., Brower, Roy G.·2005·American Journal of Respiratory and Critical Care Medicine

DOI 10.1164/rccm.200501-048cpPMC PMC2718413

Open this paper in CoChat — free account

Abstract

Use of a volume- and pressure-limited mechanical ventilation strategy improves clinical outcomes of patients with acute lung injury and acute respiratory distress syndrome (ALI/ARDS). However, the extent to which tidal volumes and inspiratory airway pressures should be reduced to optimize clinical outcomes is a controversial topic. This article addresses the question, “Is there a safe upper limit to inspiratory plateau pressure in patients with ALI/ARDS?” We reviewed data from animal models with and without preexisting lung injury, studies of normal human respiratory system mechanics, and the results of five clinical trials of lung-protective mechanical ventilation strategies. We also present an original analysis of data from the largest of the five clinical trials. The available data from each of these assessments do not support the commonly held view that inspiratory plateau pressures of 30 to 35 cm H2O are safe. We could not identify a safe upper limit for plateau pressures in patients with ALI/ARDS.

Integrity signals

Registry

Crossref · 10.1164/rccm.200501-048cp

Cites

45 of 45 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Ventilation with Lower Tidal Volumes as Compared with Traditional Tidal Volumes for Acute Lung Injury and the Acute Respiratory Distress Syndrome
(2000) · New England Journal of Medicine · doi:10.1056/nejm200005043421801 · Cited by 12,941
Robust Locally Weighted Regression and Smoothing Scatterplots
Cleveland, W. S. (1979) · Journal of the American Statistical Association · doi:10.1080/01621459.1979.10481038 · Cited by 11,594
Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome.
Amato, M. B. P., Barbas, C. S. V., Medeiros, D. M., Magaldi, R. B., Schettino, G. P., Lorenzi-Filho, G., Kairalla, R. A., Deheinzelin, D., Munoz, C., Oliveira, R., et al. (1998) · New England Journal of Medicine · doi:10.1056/nejm199802053380602 · Cited by 3,654
The APACHE III Prognostic System
Knaus, W. A., Wagner, D. P., Draper, E. A., Zimmerman, J. E., Bergner, M., BASTOS, P. G., Sirio, C., Murphy, D. J., Lotring, T., Damiano, A., et al. (1991) · CHEST Journal · doi:10.1378/chest.100.6.1619 · Cited by 3,539
The APACHE III Prognostic System
Teres, D., & Lemeshow, S. A. (1992) · CHEST Journal · doi:10.1378/chest.102.6.1919b · Cited by 2,896
Ventilator-induced Lung Injury: Lessons from Experimental Studies
Dreyfuss, D., & Saumon, G. (1998) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.157.1.9604014 · Cited by 2,262
High Inflation Pressure Pulmonary Edema: Respective Effects of High Airway Pressure, High Tidal Volume, and Positive End-expiratory Pressure
Dreyfuss, D., Soler, P., Basset, G., & Saumon, G. (1988) · American Review of Respiratory Disease · doi:10.1164/ajrccm/137.5.1159 · Cited by 1,714
Experimental pulmonary edema due to intermittent positive pressure ventilation with high inflation pressures. Protection by positive end-expiratory pressure.
Hh, W., & Tierney, D. F. (1974) · PubMed · doi:10.1164/arrd.1974.110.5.556 · Cited by 944
Low mortality associated with low volume pressure limited ventilation with permissive hypercapnia in severe adult respiratory distress syndrome
Hickling, K. G., Henderson, S. J., & Jackson, R. (1990) · Intensive Care Medicine · doi:10.1007/bf01735174 · Cited by 923
Evaluation of a Ventilation Strategy to Prevent Barotrauma in Patients at High Risk for Acute Respiratory Distress Syndrome
Stewart, T. E., Meade, M. O., Cook, D. J., Granton, J. T., Hodder, R. V., Lapinsky, S. E., Mazer, C. D., McLean, R. F., Rogovein, T. S., Schouten, B. D., et al. (1998) · New England Journal of Medicine · doi:10.1056/nejm199802053380603 · Cited by 873

Flagged first, then by citations

Show all 45 references

Research works printed but not linked: 46

1993, Chest, 1833
2005, Crit Care Med, 925
1998, N Engl J Med, 347
2000, N Engl J Med, 1301
1990, Intensive Care Med, 372
2002, Am J Respir Crit Care Med, 242
2001, Crit Care Med, 392
2003, Am J Respir Crit Care Med, 933
2005, Crit Care Med, 1141
2003, Eur Respir J Suppl, 15s
2002, Am J Respir Crit Care Med, 1510
2000, N Engl J Med, 1360
2003, Am J Respir Crit Care Med, 1297
2002, Am J Respir Crit Care Med, 1510
2002, Am J Respir Crit Care Med, 933
2002, Intensive Care Med, 230
2002, Am J Respir Crit Care Med, 1515
2004, Chest, 592
1998, Am J Respir Crit Care Med, 294
1993, Crit Care Med, 131
1946, Am J Physiol, 161
1998, N Engl J Med, 355
1999, Crit Care Med, 1492
1998, Am J Respir Crit Care Med, 1831
2003, Am J Respir Crit Care Med, A616
1993, J Pediatr Surg, 488
1988, Am Rev Respir Dis, 1159
1974, Am Rev Respir Dis, 556
1993, J Appl Physiol, 3068
1988, Intensive Care Med, 8
1990, J Appl Physiol, 956
1984, J Appl Physiol, 1809
1990, Am Rev Respir Dis, 321
1990, J Appl Physiol, 577
2004, JAMA, 1603
1993, New Horiz, 489
2005, Ann Intern Med, 283
2002, Crit Care Clin, 1
2003, Am J Respir Crit Care Med, 612
1990, Crit Care Med, 103
1991, Chest, 1619
2000, Am J Respir Crit Care Med, 209
1994, Am J Respir Crit Care Med, 1722
1971, J Appl Physiol, 909
2005, Crit Care Med, 1143
1979, J Am Stat Assoc, 829

Sorted by citations

Items 401–500 of 504

Intraoperative Ventilation Strategies for Thoracic Surgery
Macpherson, J. A. (2019) · Springer eBooks · doi:10.1007/978-3-030-00859-8_22 · Cited by 1
ECMO After EOLIA: The Evolving Role of Extracorporeal Support in ARDS
Salna, M. P., Abrams, D. C., & Brodie, D. (2019) · Annual update in intensive care and emergency medicine · doi:10.1007/978-3-030-06067-1_7 · Cited by 1
Extracorporeal CO2 removal in a case of respiratory distress syndrome by sepsis
Hernández, R. M., Rueda, F. R., & Roca, A. P. (2019) · Revista Española de Anestesiología y Reanimación (English Edition) · doi:10.1016/j.redare.2019.08.001 · Cited by 1
Extracorporeal Life Support in the Adult
Abbasi, A. A., & Ventetuolo, C. E. (2020) · Springer eBooks · doi:10.1007/978-3-030-24174-2_68 · Cited by 1
Brain–Lung Cross Talk: From Pathophysiology to Clinical Applications
Iachi, A., Robba, C., & Pelosi, P. P. (2020) · Physiology in clinical neurosciences · doi:10.1007/978-981-15-2345-8_3 · Cited by 1
Ventilators for Nonintensivists: Troubleshooting Elevations in Plateau Pressure
Acho, M., Lee, A. C., & Lee, B. W. (2020) · ATS Scholar · doi:10.34197/ats-scholar.2020-0070vo · Cited by 1
Aneurysmal Subarachnoid Hemorrhage
Bershad, E. M., & Suárez, J. I. (2021) · Elsevier eBooks · doi:10.1016/b978-0-323-69424-7.00029-6 · Cited by 1
Mechanical Ventilation
Kornecki, A., & Wheeler, D. S. (2014) · Springer eBooks · doi:10.1007/978-1-4471-6356-5_8 · Cited by 1
ARDS
Marik, P. E. (2014) · Springer eBooks · doi:10.1007/978-3-319-11020-2_23 · Cited by 1
Management of Acute Respiratory Distress Syndrome
Hyzy, R. C. (2020) · Springer eBooks · doi:10.1007/978-3-030-26710-0_21 · Cited by 1
Clinical Year in Review III: Critical Care, Mechanical Ventilation, Sleep Medicine, and Lung Cancer
Moss, M. (2006) · Proceedings of the American Thoracic Society · doi:10.1513/pats.200607-148tt · Cited by 1
Ventilation in Acute Respiratory Distress Syndrome
Fan, E., Brodie, D., & Slutsky, A. S. (2014) · Critical Care Medicine · doi:10.1097/ccm.0000000000000351 · Cited by 1
Modelling and prediction of physiological behaviour in critically ill patients
Langdon, R. (2017) · UC Research Repository (University of Canterbury) · doi:10.26021/3237 · Cited by 1
Protektive Beatmungstherapie: Auch für den OP relevant?
David, M., Bodenstein, M., & Markstaller, K. (2010) · Der Anaesthesist · Cited by 1
Know the facts of mechanical ventilation
Lian, J. X. (2008) · Men in Nursing · doi:10.1097/01.min.0000342524.33332.68 · Cited by 1
Is It Time to Put Low-Flow Extracorporeal Carbon Dioxide Removal to REST?*
Worku, E. T., Schmidt, M., & Shekar, K. (2023) · Critical Care Medicine · doi:10.1097/ccm.0000000000005889 · Cited by 1
Post‐Transplant Phase: Issues in the Early Postoperative Period
Mackintosh, J. A., & Hopkins, P. M.-A. (2023) · Wiley eBooks · doi:10.1002/9781119633884.ch89 · Cited by 1
The Lung in Multiorgan Failure
Boots, R. J. (2011) · Springer eBooks · doi:10.1007/978-3-642-03519-7_9
Take a Deep Breath—or Not*
MacIntyre, N. R. (2015) · Critical Care Medicine · doi:10.1097/ccm.0000000000001123
Efeitos fisiológicos da ventilação de alta frequência usando ventilador convencional em um modelo experimental de insuficiência respiratória grave
Cordioli, R. L. (2012) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.5.2012.tde-10102012-111936
Assessing Lung Physiology
Grinnan, D., & Truwit, J. D. (2011) · Wiley eBooks · doi:10.1002/9780470976609.ch13
Manobra de recrutamento alveolar na lesão pulmonar aguda
Steffens, J. T. C., & Campos, R. (2013) · Saúde e meio ambiente revista interdisciplinar · doi:10.24302/sma.v1i2.326
Avaliação da mecânica do sistema respiratório através da obtenção de curva PV em pacientes com pneumonia intersticial idiopática
Ferreira, J. C. (2008) · doi:10.11606/t.5.2008.tde-14042008-105330
Syndrome de détresse respiratoire aiguë : quelles sont les études à mettre en œuvre et de quel type ?
Brochard, L. J. (2006) · Réanimation · doi:10.1016/j.reaurg.2005.12.001
There is a Role for Nonbronchoscopic Lavage for Investigating Alveolar Inflammation in Acute Respiratory Distress Syndrome
Perkins, G. D., Gao, F., & THICKETT, D. R. (2006) · Critical Care Medicine · doi:10.1097/01.ccm.0000216124.28529.39
Lung Hyperinflation despite Lung-protective Ventilation
Galiatsou, E., Kostanti, E., Koulouras, V. P., & Nakos, G. (2007) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.176.5.520
Plumbing the limits of low tidal volumes for acute lung injury*
Rosenberg, A. L., & Tremper, K. K. (2007) · Critical Care Medicine · doi:10.1097/01.ccm.0000284739.63782.52
Editorial [Exogenous Surfactant for Pediatric Acute Lung Injury: Who, when and how?]
Acosta, P., & Varón, J. (2009) · Current Respiratory Medicine Reviews · doi:10.2174/157339809788922351
Clinically Relevant Assessment of the Variability of Glycemic Response and Its Affect on Surgical Site Infection Rates?
Mahmood, A., El‐Badawi, K. I., Asgeirsson, T., Gajula, V., & Senagore, A. J. (2014) · Surgical Science · doi:10.4236/ss.2014.53017
Functional residual capacity Development of new monitoring techniques for critically ill patients
Olegård, C. (2010) · Gothenburg University Publications Electronic Archive (Gothenburg University)
Imagem e mecânica pulmonar regional em duas estratégias protetoras de ventilação mecânica (ARDSNet versus PEEP ajustada pela tomografia de impedância elétrica): um estudo de longo prazo em modelo experimental
Timenetsky, K. T. (2012) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.5.2012.tde-21062012-152646
Intra-operative management
Alvarez, A., Brodsky, J. B., Lemmens, H. J. M., & Morton, J. M. (2010) · Cambridge University Press eBooks · doi:10.1017/cbo9780511676307.011
Critical assessment of the evidence
Oliveros, H., Ríos, F., & Ruiz, A. (2015) · Colombian Journal of Anesthesiology · doi:10.1016/j.rcae.2015.02.002
Comment ventiler un patient sous ECMO ou ECCO2R ?
Schmidt, M., & Combes, A. (2015) · Réanimation · doi:10.1007/s13546-015-1020-8
Review 2006: Critical Care Medicine
Koh, Y. S. (2006) · Tuberculosis & respiratory diseases · doi:10.4046/trd.2006.61.4.327
Evaluation of Respiratory Parameters in Patients with Acute Lung Injury Receiving Adaptive Support Ventilation
Lee, K. S., Chung, W. Y., Jung, Y. J., Park, J. H., Sheen, S. S., Hwang, S. C., & Park, K. J. (2011) · Tuberculosis & respiratory diseases · doi:10.4046/trd.2011.70.1.36
Respiratory Care Controversies II
Branson, R. D. (2010) · Respiratory Care · doi:10.4187/respcare.10550217
One more brick in the wall of protective ventilation in surgical patients.
Filho, R. R., & Neto, A. S. (2015) · PubMed Central · doi:10.3978/j.issn.2305-5839.2015.12.07
Two cases of acute respiratory distress syndrome associated with Legionella pneumonia successfully treated with permissive hypoxemia
Minami, E., Ishikawa, T., Mieda, H., Kawanoue, N., Iwasaki, E., Kobayashi, H., Mikane, T., & Tokioka, H. (2016) · Journal of the Japanese Society of Intensive Care Medicine · doi:10.3918/jsicm.23.158
PUESTA AL DÍA EN MEDICINA INTENSIVA: VENTILACIÓN MECÁNICA EN DIFERENTES ENTIDADES Monitorización de la mecánica respiratoria en el paciente ventilado
García-Prieto, E., & Amado‐Rodríguez, L. (2016)
Sepsis Resuscitation
Montanaro, N. J. (2015) · Critical Care Nursing Quarterly · doi:10.1097/cnq.0000000000000098
The acute respiratory distress syndrome (ARDS)
Bersten, A. D. (2009) · Elsevier eBooks · doi:10.1016/b978-0-7020-3096-3.00029-4
Acute Right Heart Failure
Krüger, W. A. (2017) · Springer eBooks · doi:10.1007/978-3-319-54973-6_4
Does High-Frequency Ventilation Have Still a Role Among the Current Ventilatory Strategies?
Mussi, R. D., & Grasso, S. (2016) · Springer eBooks · doi:10.1007/978-3-319-31398-6_4
Mechanical Ventilation in Acute Respiratory Distress Syndrome
Gattinoni, L., Carlesso, E., & Caironi, P. (2008) · Elsevier eBooks · doi:10.1016/b978-032304841-5.50013-3
Akuter Lungenschaden und akutes Atemnotsyndrom (ARDS)
Lorenz, J. (2011) · Springer eBooks · doi:10.1007/978-3-642-16970-0_31
SUNKAUS SEPSIO IR SEPTINIO ŠOKO SUKELTOS ORGANŲ SISTEMŲ DISFUNKCIJOS PREVENCIJA IR GYDYMAS
Gaižauskas, E., Judickas, Š., Balčiūnas, L., Ščupakova, N., Mockutė, L., Šerpytis, M., & Šipylaitė, J. (2016) · Medicinos teorija ir praktika · doi:10.15591/mtp.2016.011
Beatmung beim akuten Lungenversagen
Mitte, K. B., & Joannidis, M. (2012)
24for Patients with End-Stage Lung Disease
Ma, M., & Slinger, P. (2011)
43Management: Extracorporeal Ventilatory Therapy
von Dossow‐Hanfstingl, V., Deja, M., Zwißler, B., & Spies, C. (2011)
CLINICAL EXPERIENCE WITH THE ILA MEMBRANE VENTILATOR IN INTENSIVE CARE UNIT TIMISOARA
Gîndac, C., Dragulescu, D. M., Neamţu, C., Păpurică, M., Bedreag, O. H., & Săndesc, D. (2015)
Erişkin Akut Solunum Sıkıntısı Sendromu Olan Hastalarda Ekstrakorporeal Yaşam Desteği: Derleme
Ayazoğlu, T. A., & Önk, D. (2015) · Türk yoğun bakım derneği dergisi/Türk yoğun bakım dergisi · doi:10.4274/tybdd.35220
Comparative analysis of parameters of oxygenation, ventilation and acid-base status during intraoperative application of conventional and protective lung ventilation
Videnović, N., Trpkovic, S., Mladenović, J., Pavlovic, A. P., Filipovic, M., Videnovic, V., & Zdravković, R. (2015) · Praxis medica · doi:10.5937/pramed1503023v
Acute respiratory failure: From intubation to ECMO
Hassan, I. F. (2017) · Qatar medical journal · doi:10.5339/qmj.2017.swacelso.13
Ventilation Strategies: High-Frequency Oscillatory Ventilation
Mentzelopoulos, S. D., Karlis, G., Pantazopoulos, I. N., & Vrettou, C. S. (2017) · Springer eBooks · doi:10.1007/978-3-319-41852-0_4
Management of Acute Respiratory Distress Syndrome
Hyzy, R. C. (2017) · Springer eBooks · doi:10.1007/978-3-319-43341-7_21
Perioperative Lung Protection Strategies in One-lung and Two-lung Ventilation
Slinger, P. (2015) · ASA Refresher Courses in Anesthesiology · doi:10.1097/asa.0000000000000024
Ventilatory Management of ARDS Before and During ECMO
Bellani, G., Grasselli, G., & Pesenti, A. M. (2014) · Springer eBooks · doi:10.1007/978-88-470-5427-1_20
Special Considerations for the Septic Patient Going to the Operating Room
Derouen, J. (2018) · Critical Care Nursing Clinics of North America · doi:10.1016/j.cnc.2018.05.008
¿QUÉ HEMOS APRENDIDO DE FALLA RESPIRATORIA CATASTRÓFICA?
Moralesa, D., Tapía, P., Mercado, P., & Ortiz, C. (2019) · Revista Médica Clínica Las Condes · doi:10.1016/j.rmclc.2019.02.001
Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome: The Doctors are In, but the Jury is Still Out
Wacker, D. A. (2019) · Clinical Pulmonary Medicine · doi:10.1097/cpm.0000000000000298
Understanding the Current Role and Future Application of Extracorporeal Life Support in Acute Respiratory Distress Syndrome
Rudym, D., Melville, K. E., Cummings, M. J., & Abrams, D. C. (2019) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201904-0814rr
Eliminación extracorpórea de CO2 en un caso de síndrome de distrés respiratorio por sepsis
Hernández, R. M., Rueda, F. R., & Roca, A. P. (2019) · Revista Española de Anestesiología y Reanimación · doi:10.1016/j.redar.2019.08.004
Noninvasive and Mechanical Ventilation
Gaillard, J. P., & Schinlever, M. (2020) · Springer eBooks · doi:10.1007/978-3-030-28794-8_4
ERKRANKUNGEN DER ATMUNGSORGANE
Jung, N., Mayet, W.-J., Mertens, P. R., (federführend), J. M., Müller, O.-A., Pfeifer, R., Schellinger, P. D., Weiss, N., & Wendtner, C. (2020) · Elsevier eBooks · doi:10.1016/b978-3-437-06282-7.50010-3
Postoperative Complications and Management
Pasero, D., Lees, N. J., Costamagna, A., Ellena, M., Montrucchio, G. G., & Brazzi, L. (2020) · Springer eBooks · doi:10.1007/978-3-030-40679-0_81
Fokus Beatmung, Sauerstofftherapie und Weaning
Fiedler, M. O., Reuß, C. J., Bernhard, M. H., Beynon, C., Hecker, A., Jungk, C., Nußhag, C., Michalski, D., Brenner, T., Weigand, M. A., et al. (2020) · Der Anaesthesist · doi:10.1007/s00101-020-00859-7
“Established” Respiratory Treatment in Acute Respiratory Distress Syndrome: Scientific Rigor or a Square Peg in a Round Hole?
Camporota, L., Gattinoni, L., & Marini, J. J. (2020) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.202011-4163le
Modes and Strategies of Mechanical Ventilation in ARDS
Sun, Q., Xie, J., & Qiu, H. (2020) · Springer eBooks · doi:10.1007/978-981-15-7056-8_8
Revista Colombiana de Anestesiología
Oliveros, H., Ríos, F., & Ruiz, A. N. (2012)
Fokus Beatmung, Sauerstofftherapie und Weaning 2021/2022
Fiedler, M. O., Dietrich, M., Reuß, C. J., Bernhard, M. H., Beynon, C., Hecker, A., Jungk, C., Nußhag, C., Michalski, D., Weigand, M. A., et al. (2023) · Die Anaesthesiologie · doi:10.1007/s00101-023-01250-y
Fokus Beatmung, Sauerstofftherapie und Weaning
Fiedler, M. O., Reuß, C. J., Bernhard, M. H., Beynon, C., Hecker, A., Jungk, C., Nußhag, C., Michalski, D., Brenner, T., Weigand, M. A., et al. (2021) · Der Anaesthesist · doi:10.1007/s00101-021-00979-8
Mechanical Ventilation – Part II: Monitoring of Respiratory Mechanics During Mechanical Ventilation and Ventilator Strategies
Marchetti, N. T., Remakus, C. B., Martin, U. J., & Criner, G. J. (2010) · Springer eBooks · doi:10.1007/978-0-387-77452-7_45
Mechanical Ventilation
Krüger, W. A., & Ludman, A. J. (2014) · Springer eBooks · doi:10.1007/978-3-642-54971-7_1
Ards
Marik, P. E. (2010) · Springer eBooks · doi:10.1007/978-1-4419-5923-2_19
The “open lung” compromise
Marini, J. J. (2012) · Springer eBooks · doi:10.1007/978-3-642-28233-1_49
Mechanical Ventilation
MacIntyre, N. R. (2011) · Elsevier eBooks · doi:10.1016/b978-1-4377-1367-1.00048-3
Potential Mechanisms by which Statins Modulate the Development of Acute Lung Injury
Craig, T. R., O’Kane, C. M., & McAuley, D. F. (2007) · Springer eBooks · doi:10.1007/978-0-387-49518-7_25
Plateau Pressures in the ARDSnet Protocol: Cause of Injury or Indication of Disease?
Ranieri, V. M., Gattinoni, L., & Slutsky, A. S. (2007) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.176.1.100
Respiratory System Mechanics and Energetics
Ayas, N., Zakynthinos, S. G., Roussos, C., & Paré, P. A. (2010) · Elsevier eBooks · doi:10.1016/b978-1-4160-4710-0.00005-5
High-Frequency Oscillation and Prone Position
Papazian, L. (2006) · Critical Care Medicine · doi:10.1097/01.ccm.0000216700.97489.f9
Faculty Opinions recommendation of The future of mechanical ventilation: lessons from the present and the past.
Truwit, J. D. (2018) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.727804624.793549471
Faculty Opinions recommendation of Guidelines on the management of acute respiratory distress syndrome.
Hibbert, K. A. (2019) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.736017663.793567298
What Are the Benefits of Different Ventilatory Techniques?
Cereda, M. F., & Gold, A. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-77846-6.00028-8
Lung Rescue and ECMO
Sobieszczyk, M. J., Biscotti, M., & Cannon, J. W. (2022) · Springer eBooks · doi:10.1007/978-3-031-06959-8_24
Mechanical Ventilation in COVID-19 Acute Respiratory Distress Syndrome Phenotypes
Kömürcü, Ö., Küllaç, S., Yılmaz, A., & Ülger, F. (2022) · Türk yoğun bakım derneği dergisi/Türk yoğun bakım dergisi · doi:10.4274/tybd.galenos.2022.30301
What Are the Benefits of Different Ventilatory Techniques?
Cereda, M. F. (2013) · Elsevier eBooks · doi:10.1016/b978-1-4557-2768-1.00021-x
Tidal volume in mechanically ventilated patients: Searching for Cinderella’s shoe rather than 6 mL/kg for all
Mounier, R., Diop, S., Kallel, H., Constantin, J.-M., & Roujansky, A. (2024) · Anaesthesia Critical Care & Pain Medicine · doi:10.1016/j.accpm.2024.101356
Ventilatory load reduction by combined mild hypothermia and ultraprotective mechanical ventilation strategy in severe COVID-19-related acute respiratory distress syndrome: A physiological study
Pablo Cruces, R., Moreno, D., Reveco, S., Ramírez, Y., & Díaz, F. (2024) · Turkish Journal of Emergency Medicine · doi:10.4103/tjem.tjem_339_22
Острый респираторный дистресс-синдром: пути оптимизации респираторной поддержки в зависимости от паттерна и механики дыхания
Росстальная, А. Л., & Махсудов, Д. Р. (2024) · The Bulletin of Emergency Medicine · doi:10.54185/tbem/vol16_iss4/a17
Extracorporeal Support for Acute Respiratory Distress Syndrome
Greendyk, R. A., Abrams, D. C., Agerstrand, C. L., Parekh, M. J., & Brodie, D. (2024) · Clinics in Chest Medicine · doi:10.1016/j.ccm.2024.08.012
Acute respiratory distress syndrome
Bersten, A. D., & Bihari, S. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-11611-7.00037-2
Additional file 1 of The use of extracorporeal CO2 removal in acute respiratory failure
Giraud, R., Banfı, C., Assouline, B., Charrière, A. D., Cecconi, M., & Bendjelid, K. (2021) · Figshare · doi:10.6084/m9.figshare.14431970
Additional file 2 of The use of extracorporeal CO2 removal in acute respiratory failure
Giraud, R., Banfı, C., Assouline, B., Charrière, A. D., Cecconi, M., & Bendjelid, K. (2021) · Figshare · doi:10.6084/m9.figshare.14431973
Additional file of The use of extracorporeal CO2 removal in acute respiratory failure
Giraud, R., Banfı, C., Assouline, B., Charrière, A. D., Cecconi, M., & Bendjelid, K. (2021) · Figshare · doi:10.6084/m9.figshare.14431976
Additional file 1 of Practical assessment of risk of VILI from ventilating power: a conceptual model
Marini, J. J., Thornton, L. T., Rocco, P. R., Gattinoni, L., & Crooke, P. S. (2024) · Figshare · doi:10.6084/m9.figshare.26583936
Saudi Guideline for Mechanical Ventilation in Adults
Arabi, Y. M., Aseri, Z. A. A., Gabriel Rada, G., Abdulmomen, A., Alenezi, F. Z., bshabshe, A. A. A. A., Aldekhyl, S., Algahtani, A. I., Algethamy, H. M., Al-Hameed, F. M., et al. (2026) · Saudi Journal of Medicine and Medical Sciences · doi:10.4103/sjmms.sjmms_327_25
Waveform data capture substantial variation in tidal volume and other respiratory parameters
Moin, E. E., Bennett, R. M., Moffett, A. T., Schmid, B. E., Long, K., Seewald, N. J., Reilly, J. P., & Weissman, G. E. (2026) · Annals of the American Thoracic Society · doi:10.1093/annalsats/aaoag024
Étude des lésions pulmonaires associées à la ventilation mécanique par imagerie synchrotron
Broche, L. (2015) · doi:10.70675/ec046374z9fd9z4428zb742zf17ac1f53c39
Apport de la tomographie par impédance électrique pour personnaliser la ventilation mécanique au cours du syndrome de détresse respiratoire aigu réfractaire traité par ECMO veino-veineuse
Franchineau, G. (2021) · theses.fr (ABES) · doi:10.70675/f17008c3z3a3dz4cd8zbeefzc2f4bcdca047

Authors: Hager, D. N., Krishnan, J. A., Hayden, D. L., & Brower, R. G.
Affiliations: Johns Hopkins University (US)
ORCID: Hager, David N.
Krishnan, Jerry A.
Venue: American Journal of Respiratory and Critical Care Medicine
Publisher: Oxford University Press (OUP)
Published: 2005-11
Volume: 172
Issue: 10
Pages: 1241-1245
ISSN: 1073-449X (ISSN-L)
1535-4970
DOI: 10.1164/rccm.200501-048cp
PMC: PMC2718413
OpenAlex: W2168829312
Cited by: 509
References: 45
Citations by year: 2026: 5 · 2025: 5 · 2024: 12 · 2023: 7 · 2022: 17 · 2021: 28 · 2020: 29 · 2019: 25 · 2018: 16 · 2017: 34 · 2016: 28 · 2015: 34 · 2014: 34 · 2013: 29 · 2012: 30
FWCI: 4.59
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: academic.oup.com/pages/standard-publication-reuse-rights (vor)
Locations: American Journal of Respiratory and Critical Care Medicine (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (n01hr046063-006, n01hr046064-009)
National Heart, Lung, and Blood Institute (K23HL067850, N01-HR-46063, K23-HL67850, P50HL073944, N01-HR46064, F32HL078132)
Topics: Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Respiratory Support and Mechanisms
Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Neonatal Respiratory Health Research
Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Nosocomial Infections in ICU
Keywords: acute lung injury, acute respiratory distress syndrome, tidal volume reduction, plateau pressure, lung-protective ventilation, pressure-limited ventilation, ventilator-induced lung injury, respiratory mechanics, animal models of lung injury
MeSH terms: Animals, Humans, Respiration, Artificial, Respiratory Distress Syndrome, Tidal Volume, Logistic Models, Models, Animal

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Tidal Volume Reduction in Patients with Acute Lung Injury When Plateau Pressures Are Not High

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks